Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Healthy & Lite Shake Vanilla Ingredients & Drug Interactions

by Spectra Wellness Solutions

Healthy & Lite Shake Vanilla label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Healthy & Lite Shake Vanilla against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Healthy & Lite Shake Vanilla is a dietary supplement by Spectra Wellness Solutions with 6 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,035 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Sodium, Rice Protein. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Healthy & Lite Shake Vanilla by Spectra Wellness Solutions

Ask about any prescription or over-the-counter medication and we check it for interactions with Healthy & Lite Shake Vanilla by Spectra Wellness Solutions — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Healthy & Lite Shake Vanilla by Spectra Wellness Solutions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 4 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (28 Gram(s)) without saying how much of each component you get.

This shake powder contains three active ingredients. Sodium is included in the formula — a mineral your body needs in small amounts, though the amount in this product isn't specified on the label.

Rice protein and pea protein isolate are the two protein sources, which help provide protein content for the shake. The product also contains inactive ingredients (flavors, stevia extract, and silicon dioxide) that add taste and texture.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: weight loss and wellness meal replacement shake.
  • We looked for evidence on: Obesity, Constipation, Diarrhea, Hyperlipidemia, Diabetes, Exercise-induced muscle damage — and 4 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Black Psyllium is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Diarrhea, Obesity.
  • Also on file: Pea Protein is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Exercise-induced muscle soreness, Hyperlipidemia.

The evidence on what this shake can do varies by ingredient. Sodium is likely effective for cystic fibrosis and possibly effective for reducing kidney damage from the drug amphotericin B, but we don't have reliable evidence it helps with bipolar disorder or congestive heart failure.

Rice protein is possibly effective for food allergies, though evidence for exercise soreness and muscle strength is insufficient. Pea protein isolate has insufficient evidence for the conditions we hold data on — diabetes, exercise soreness, high cholesterol, high blood pressure, and irritable bowel syndrome — so we can't say whether it helps with those.

The evidence, ingredient by ingredient Black Psyllium Sodium Rice Protein Pea Protein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sodium is well tolerated in normal dietary amounts, but too much is linked to high blood pressure and heart disease. The facts caution against sodium supplements or very high intake without talking to your doctor first — usual food sodium is fine.

Rice protein is generally well tolerated as a food, though allergies to rice have been reported rarely; enterocolitis (intestinal inflammation) has been reported in young children. Pea protein may trigger allergic reactions in people sensitive to other legumes — a small number of cases describe anaphylaxis, angioedema, hives, and asthma in children with food allergies.

For pregnancy and breastfeeding: sodium safety data shows conflicting ratings (likely safe in one entry, possibly unsafe in another), so talk with your doctor. Rice protein and pea protein as concentrated supplements have not been well studied in pregnancy or breastfeeding — check with your healthcare provider for personalized advice.

Side effects, ingredient by ingredient Black Psyllium Sodium Rice Protein Pea Protein

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Black Psyllium, Sodium, Rice Protein.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,036 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this shake, double-check with your doctor or pharmacist if you take any antihypertensive drugs (blood pressure medications), ACE inhibitors, corticosteroids, lithium, didanosine, sodium phosphates, tolvaptan, or any other sodium-containing medication. High sodium intake can interfere with blood pressure control and raise the risk of high sodium levels in your blood — these are Moderate-severity concerns.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This shake is a protein-and-sodium product that's generally well tolerated as a food supplement in healthy adults. If you take blood pressure medications, lithium, corticosteroids, or any other blood pressure or sodium-related drug, you need to check with your doctor or pharmacist before adding this to your routine — the sodium and rice protein could affect how those drugs work.

Talk it over with your healthcare provider, especially if you have high blood pressure, heart disease, or kidney issues.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 10, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Healthy & Lite Shake Vanilla, straight from the product label.

Brand Spectra Wellness Solutions
Barcode (UPC) 693749003755
Net contents 32.6 oz.; 2.0375 lbs; 927 Gram(s)
Market status On market
Date entered into DSLD Oct 10, 2014
DSLD ID 37415
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Healthy & Lite Shake Vanilla by Spectra Wellness Solutions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Level Scoop(s)
Maximum serving Sizes:
1 Level Scoop(s)
Servings per container
30
UPC/BARCODE
693749003755
IngredientAmount% DV
Calories120 {Calories}--
Total Carbohydrates1 Gram(s)1%
Sugar1 Gram(s)--
Calories from Fat20 {Calories}--
Dietary Fiber1 Gram(s)--
Protein24 Gram(s)48%
Saturated Fat0.5 Gram(s)2%
Sodium400 mg16%
Trans Fat0 Gram(s)--
Cholesterol0 mg--
Total Fat2 Gram(s)3%
Proprietary Blend28 Gram(s)--
Rice Protein0 NP--
Pea Protein isolate0 NP--

Other ingredients: Flavors, Stevia extract, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

Suggested Use: Mix one level scoop of powder with 10 oz. of water, juice, or preferred beverage daily or as recommended by your health-care practitioner.

General Statements

Typical Amino Acid Amounts (g) Per Serving: Alanine 1.0 Arginine 2.0 Aspartic Acid 2.7 Cysteine 0.2 Glutamic Acid 3.9 Glycine 0.9 Histidine 0.6 Isoleucine 1.2 Leucine 1.9 Lysine 1.7 Methionine 0.3 Phenylalanine 1.3 Proline 1.0 Serine 1.1 Threonine 0.9 Tyrosine 0.9 Valine 1.2 Essential Amino Acid

THE KOCHE APPROACH 1-CLEAN-2-3-4 YOUR WAY TO WEIGHT LOSS & WELLNESS CREATED BY LISA SAFF KOCHE, M.D. & SPECTRA SOLUTIONS

Precautions

Tamper Evident: Use only if bottle is sealed.

If pregnant consult your health-care practitioner before using this product.

Storage

Store tightly sealed in a cool, dry place.

General

KOCSP673_02

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Healthy & Lite Shake Vanilla by Spectra Wellness Solutions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Healthy & Lite Shake Vanilla label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Healthy & Lite Shake Vanilla by Spectra Wellness Solutions

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Level Scoop(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 Gram(s) per serving

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

24 Gram(s) per serving

Sodium

Interacts with
205 drugs
400 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Proprietary Blend

28 Gram(s) per serving

Other (inactive) ingredients: Flavors, Stevia extract, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Healthy & Lite Shake Vanilla by Spectra Wellness Solutions Drug Interactions

Want to check YOUR meds against Healthy & Lite Shake Vanilla?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,035Drugs
227 Moderate 1,808 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Sodium 205
Rice Protein 23

Individual Drug Interactions

The ingredients in Healthy & Lite Shake Vanilla interact with 2,035 drugs. Click any drug to see the details.

3 of the 6 ingredients in Healthy & Lite Shake Vanilla interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Sodium Rice Protein

Each ingredient & the kinds of drugs it affects

For each ingredient in Healthy & Lite Shake Vanilla with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Rice Protein1 drug type · 23 drugs

Ace Inhibitors (Aceis)

In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE). In animal research, the inhibition of ACE is correlated with a reduction in systolic blood pressure. So far, this effect has not been shown in humans. Theoretically, concomitant use of rice protein and ACE inhibitors may increase the risk of blood pressure becoming too low. Use with caution. ACE inhibitors include benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik).

Likelihood Possible Evidence D
Rice Protein full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Healthy & Lite Shake Vanilla, from the product label.

Spectra Wellness Solutions

See all Spectra Wellness Solutions products
Name
Spectra Wellness Solutions
Street Address
509 S. Armenia Suite 302
City
Tampa
State
FL
ZipCode
33609
Phone Number
(813) 319-0911
Web Address
www.spectracomplete.com
Pharmacist Counseling Corner

Healthy & Lite Shake Vanilla by Spectra Wellness Solutions: Common Questions

Does Healthy & Lite Shake Vanilla by Spectra Wellness Solutions interact with any medications?
Yes. Based on its ingredients, Healthy & Lite Shake Vanilla has a known interaction with 2,035 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Healthy & Lite Shake Vanilla contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this shake have a lot of sodium in it?
The product contains sodium, but the amount per serving isn't listed on the facts we have. Because sodium interacts with several blood pressure and heart medications, if you take any of those, ask your doctor or pharmacist about whether this shake fits your diet.
Is this safe if I'm pregnant or breastfeeding?
The safety data on sodium during pregnancy is mixed — one rating says likely safe, another says possibly unsafe — so you'll need to talk with your doctor. For the protein ingredients (rice and pea), safety in pregnancy and breastfeeding hasn't been well studied in concentrated supplement form, so check with your healthcare provider for personalized guidance.
Can this help me build muscle?
We don't have reliable evidence that the ingredients in this shake boost muscle strength or reduce exercise soreness. It's a source of protein, which your body needs, but the effectiveness data on these particular proteins for muscle-building is insufficient.
Will this work for food allergies?
Rice protein is possibly effective for food allergies. But be aware — allergies to rice protein itself have been reported rarely, and pea protein can trigger reactions in people with other food allergies, including legume sensitivities. If you have a history of food allergies, check the ingredients carefully or talk with your doctor first.
Is pea protein safe?
Pea protein is generally well tolerated by most healthy people. However, a small number of cases describe allergic reactions (including anaphylaxis) in children with existing food allergies to peanuts, tree nuts, or other legumes — so if you or your family have those allergies, be cautious.
What's the proprietary blend?
The label lists a proprietary blend, which means the exact amounts of its component ingredients are not disclosed separately — only their individual names. This is standard for some supplement formulas, but it means you can't see the precise amount of each ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Healthy & Lite Shake Vanilla label
Go deeper

The Full Monographs Behind Healthy & Lite Shake Vanilla’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Rice Protein

Interacts with 23 drugs

Rice protein is a plant-based protein powder made from rice that offers an easy way to add protein to your diet, especially if you avoid dairy or animal products. It is generally considered...

Read the full Rice Protein monograph → Herb & supplement monograph

Pea Protein

Pea protein is a plant-based protein powder made from yellow split peas, commonly used by people who want a dairy-free or vegan source of protein to support muscle and overall protein intake...

Read the full Pea Protein monograph →
Sources

Sources & How We Checked

Healthy & Lite Shake Vanilla's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 63 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
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See these in context on the Sodium monograph →

Rice Protein 6 references
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See these in context on the Rice Protein monograph →

Pea Protein 1 reference
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See these in context on the Pea Protein monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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