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Dietary supplement

High Potency DMAE 250 mg Ingredients & Drug Interactions

by Swanson Ultra

High Potency DMAE 250 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking High Potency DMAE 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

High Potency DMAE 250 mg is a dietary supplement by Swanson Ultra with 1 active ingredient. Its ingredients are commonly taken for memory and focus, mood and mental clarity, adhd-type symptoms.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are DMAE. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against High Potency DMAE 250 mg by Swanson Ultra

Ask about any prescription or over-the-counter medication and we check it for interactions with High Potency DMAE 250 mg by Swanson Ultra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of High Potency DMAE 250 mg by Swanson Ultra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: DMAE (deanol) at 250 mg per softgel capsule. The remaining ingredients — soybean oil, gelatin, glycerin, yellow beeswax, lecithin, deionized water, and carob — are inactive components that form the softgel capsule and keep the product stable.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Deanol product and its label doesn't state a use — see Deanol's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on DMAE is limited. It's been studied for Alzheimer disease and tardive dyskinesia (a movement disorder that can develop from long-term use of certain psychiatric medications), but testing has shown it likely ineffective for both.

For aging skin, athletic performance, and ADHD, we don't have enough reliable evidence to know whether it works. The data we hold doesn't establish that this product is effective for any condition.

The evidence, ingredient by ingredient Deanol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

DMAE is generally well tolerated by some adults, though the safety evidence is limited and side effects do occur. The most common ones reported orally are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting.

At higher doses — especially above 1000 mg daily — it's been linked to mood changes like depression and hypomania, and in people with schizophrenia, it may worsen symptoms. Because animal research raises safety concerns and not enough data exists on DMAE in pregnancy and breastfeeding, these groups should avoid it.

If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Deanol

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Deanol.
  • The most serious interaction on file is rated Minor.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this product, double-check any anticholinergic or cholinergic medications you take — DMAE may weaken the first type and amplify both the effects and side effects of the second. Use the medication search tool on this page to see whether any of your prescriptions are affected, and confirm with your doctor or pharmacist before combining them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

DMAE is generally well tolerated at this dose, but evidence for its effectiveness is weak or absent for the conditions it's marketed for. If you take anticholinergic or cholinergic medications, check them against this product before starting.

Anyone who is pregnant, breastfeeding, or has a history of mood or psychiatric conditions should discuss this supplement with their doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about High Potency DMAE 250 mg, straight from the product label.

Brand Swanson Ultra
Barcode (UPC) 087614025377
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD May 24, 2018
DSLD ID 176619
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for High Potency DMAE 250 mg by Swanson Ultra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
087614025377
IngredientAmount% DV
DMAE250 mg--

Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Lecithin, deionized Water, Carob

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The most advanced nutrition technology Softgels

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

Formula

(Dimethylaminoethanol)

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Guaranteed purity & potency

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Warning: Do not use if you are pregnant or nursing.

Consult your healthcare provider before using this product if you have a medical condition, especially depression, schizophrenia or epilepsy.

Storage

Store in a cool, dry place. Do not refrigerate.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one softgel per day with water.

General

SWU537 Rev 0 12 14 17

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

High Potency DMAE 250 mg by Swanson Ultra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

High Potency DMAE 250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in High Potency DMAE 250 mg by Swanson Ultra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

DMAE

Interacts with
219 drugs
250 mg per serving Form: Dimethylaminoethanol Bitartrate

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...

DMAE monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Lecithin, Deionized Water, Carob. These complete the product’s ingredient list but are not active constituents.

Interaction report

High Potency DMAE 250 mg by Swanson Ultra Drug Interactions

Want to check YOUR meds against High Potency DMAE 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
219Drugs
219 Minor

Ingredients driving the most interactions

DMAE 219

Individual Drug Interactions

The ingredients in High Potency DMAE 250 mg interact with 219 drugs. Click any drug to see the details.

1 of the 1 ingredient in High Potency DMAE 250 mg interact with drugs. Each result below shows which ingredient is responsible. DMAE

Each ingredient & the kinds of drugs it affects

For each ingredient in High Potency DMAE 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

DMAE2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Cholinergic Drugs

Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
DMAE full monograph & interactions
The maker

Brand information

Manufacturer and brand details for High Potency DMAE 250 mg, from the product label.

Swanson Ultra

See all Swanson Ultra products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

High Potency DMAE 250 mg by Swanson Ultra: Common Questions

Does High Potency DMAE 250 mg by Swanson Ultra interact with any medications?
Yes. Based on its ingredients, High Potency DMAE 250 mg has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
High Potency DMAE 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is DMAE, and what is it supposed to do?
DMAE (also called deanol) is a compound thought to increase acetylcholine, a chemical messenger in the brain. It's been studied for memory problems, movement disorders, and aging skin, but the evidence doesn't show it works well for any of these. Your doctor or pharmacist can tell you more about whether it makes sense for your situation.
What are the most common side effects?
The most frequently reported side effects are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting. Headache, insomnia, and overstimulation have also been reported. If you notice any of these, stop taking it and talk to your pharmacist or doctor.
Is DMAE safe to take while pregnant or breastfeeding?
No. There isn't enough safety data for pregnancy, and some animal research raises concerns, so DMAE should be avoided during pregnancy and while breastfeeding. If you're pregnant, planning pregnancy, or nursing, talk with your doctor or pharmacist before considering any supplement.
Can DMAE worsen mood or psychiatric symptoms?
Yes. At doses above 1000 mg daily, DMAE has been linked to mood changes like depression and hypomania. In people with schizophrenia, it may worsen symptoms. If you have a history of depression, bipolar disorder, schizophrenia, or other psychiatric conditions, discuss this product with your doctor or pharmacist first.
Does this product contain any fillers or artificial ingredients?
The softgel capsule itself is made from gelatin, glycerin, soybean oil, yellow beeswax, lecithin, deionized water, and carob. These are inactive ingredients that form and preserve the capsule, not active components meant to have a therapeutic effect.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if High Potency DMAE 250 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

High Potency DMAE 250 mg label
Go deeper

The Full Monographs Behind High Potency DMAE 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Deanol

Interacts with 219 drugs

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limited or mixed. It can cause side effects in...

Read the full Deanol monograph →
Sources

Sources & How We Checked

High Potency DMAE 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deanol 15 references
  1. Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
  2. Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
  3. Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
  4. George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
  5. Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
  6. de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
  7. Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
  8. Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
  9. Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
  10. Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
  11. Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
  12. Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
  13. Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
  14. Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
  15. Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.

See these in context on the Deanol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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