Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Pharmaceutical Grade AjiPure L-Glutamine Powder Ingredients & Drug Interactions

by Swanson Ultra

Pharmaceutical Grade AjiPure L-Glutamine Powder label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pharmaceutical Grade AjiPure L-Glutamine Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pharmaceutical Grade AjiPure L-Glutamine Powder is a dietary supplement by Swanson Ultra with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pharmaceutical Grade AjiPure L-Glutamine Powder by Swanson Ultra

Ask about any prescription or over-the-counter medication and we check it for interactions with Pharmaceutical Grade AjiPure L-Glutamine Powder by Swanson Ultra — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Pharmaceutical Grade AjiPure L-Glutamine Powder by Swanson Ultra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: L-glutamine powder. L-glutamine is an amino acid (a building block your body uses to make proteins and other compounds).

There are no other active ingredients, and no inactive fillers or additives are listed.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glutamine's overall clinical evidence instead.

Strong

Strong clinical evidence supports Glutamine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Sickle cell disease — rated "Effective" (Natural Medicines).
  • On file: HIV/AIDS-related wasting — rated "Possibly Effective" (Natural Medicines).
  • On file: Critical illness (trauma) — rated "Possibly Effective" (Natural Medicines).
  • On file: Postoperative recovery — rated "Possibly Effective" (Natural Medicines).
  • On file: Pancreatitis — rated "Possibly Effective" (Natural Medicines).

The evidence supporting L-glutamine is strongest for sickle cell disease, where it's rated Effective. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence is rated Possibly Effective — meaning some research suggests a benefit, but more data is needed to be certain.

If you're considering this supplement for any of these conditions, discuss it with your doctor to see if it fits your individual situation.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated in healthy adults when taken by mouth. The most common side effects are gastrointestinal — belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, and stomach pain — especially at higher doses (10–30 grams daily or higher).

Headache, dizziness, and musculoskeletal pain have also been reported. A very small number of people with bipolar disorder taking high doses (up to 4 grams daily) have reported mania or hypomania.

If you have kidney or liver disease, use this supplement only under medical supervision. Because safety data in pregnancy and breastfeeding is limited, talk with your doctor or pharmacist before taking it in those situations — the research we hold does not tell us whether it's safe at supplement doses for these groups.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant medications (seizure-prevention drugs), check with your doctor or pharmacist before adding this supplement — L-glutamine theoretically might reduce how well they work, though this hasn't been confirmed in humans yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

L-glutamine may be worth considering if you have sickle cell disease (where evidence is strongest) or are recovering from surgery or critical illness (where evidence is promising but less certain). If you take anticonvulsant medication, check with your doctor or pharmacist first — there's a theoretical interaction we need to rule out.

People with kidney or liver disease, and those who are pregnant or breastfeeding, should discuss this supplement with their healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pharmaceutical Grade AjiPure L-Glutamine Powder, straight from the product label.

Brand Swanson Ultra
Barcode (UPC) 087614024288
Net contents 12 Oz(s); 340 Gram(s)
Market status On market
Date entered into DSLD Jul 25, 2018
DSLD ID 177771
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pharmaceutical Grade AjiPure L-Glutamine Powder by Swanson Ultra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
68
UPC/BARCODE
087614024288
IngredientAmount% DV
L-Glutamine, Powder5 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The most advanced nutrition technology Powder

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

AjiPure amino acids Guaranteed purity & potency

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Warning: Not intended for use by children or pregnant or nursing women.

Warning: Not intended for use by children or pregnant or nursing women.

Consult your healthcare provider before use if you have a renal or liver disorder.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, mix one scoop (5 g) into juice or water once per day. Scoop included.

Brand IP Statement(s)

AjiPure and the AjiPure logo are registered trademarks of Ajinomoto, Inc.

General

SWU428 Rev 0 07 06 17

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pharmaceutical Grade AjiPure L-Glutamine Powder by Swanson Ultra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pharmaceutical Grade AjiPure L-Glutamine Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pharmaceutical Grade AjiPure L-Glutamine Powder by Swanson Ultra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container68 Amounts shown are per serving.

L-Glutamine, Powder

Interacts with
50 drugs
5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine, Powder monograph & interactions
Interaction report

Pharmaceutical Grade AjiPure L-Glutamine Powder by Swanson Ultra Drug Interactions

Want to check YOUR meds against Pharmaceutical Grade AjiPure L-Glutamine Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine, Powder 50

Individual Drug Interactions

The ingredients in Pharmaceutical Grade AjiPure L-Glutamine Powder interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pharmaceutical Grade AjiPure L-Glutamine Powder interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Pharmaceutical Grade AjiPure L-Glutamine Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine, Powder1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pharmaceutical Grade AjiPure L-Glutamine Powder, from the product label.

Swanson Ultra

See all Swanson Ultra products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Pharmaceutical Grade AjiPure L-Glutamine Powder by Swanson Ultra: Common Questions

Does Pharmaceutical Grade AjiPure L-Glutamine Powder by Swanson Ultra interact with any medications?
Yes. Based on its ingredients, Pharmaceutical Grade AjiPure L-Glutamine Powder has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pharmaceutical Grade AjiPure L-Glutamine Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-glutamine and what does it do in my body?
L-glutamine is an amino acid — one of the building blocks your body uses to make proteins and other compounds. It plays various roles in metabolism, immune function, and gut health. Your body makes some on its own, and you get more from protein-containing foods.
What are the most common side effects?
Stomach upset is most common: bloating, constipation, diarrhea, nausea, and vomiting, especially at higher doses. Headache, dizziness, belching, and muscle pain have also been reported. Most people tolerate it well, but if your stomach gets uncomfortable, try a lower dose or talk with your pharmacist.
Is it safe to take while pregnant or breastfeeding?
The safety data we have isn't detailed enough to know either way at supplement doses. Talk with your doctor or pharmacist before taking it during pregnancy or while breastfeeding — they can weigh your individual situation and advise you.
Will this work for sickle cell disease?
Evidence shows L-glutamine is Effective for sickle cell disease. For other uses like postoperative recovery or HIV-related wasting, the evidence is Possibly Effective — meaning research suggests benefit, but we need more data. Discuss with your doctor whether it's appropriate for your condition.
Is there anything I should know if I have kidney or liver problems?
Yes — if you have kidney or liver disease, use this supplement only under medical supervision. Your doctor or pharmacist needs to know your kidney and liver function before you start.
Does it have any fillers or other inactive ingredients?
No — this product is L-glutamine powder with no fillers, binders, or other inactive ingredients listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pharmaceutical Grade AjiPure L-Glutamine Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pharmaceutical Grade AjiPure L-Glutamine Powder label
Go deeper

The Full Monographs Behind Pharmaceutical Grade AjiPure L-Glutamine Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Pharmaceutical Grade AjiPure L-Glutamine Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team