Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

HLC Baby B Ingredients & Drug Interactions

by Pharmax

HLC Baby B label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking HLC Baby B against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

HLC Baby B is a dietary supplement by Pharmax with 4 active ingredients. Its ingredients are commonly taken for digestive health and regularity, constipation relief, immune support.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium animalis subsp. lactis (CUL-34), Bifidobacterium bifidum (CUL-20). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against HLC Baby B by Pharmax

Ask about any prescription or over-the-counter medication and we check it for interactions with HLC Baby B by Pharmax — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of HLC Baby B by Pharmax

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “HLC Consortium” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

HLC Baby B is a powder containing 4 active probiotic ingredients: two Bifidobacterium species (B. animalis subsp. lactis and B. bifidum), Lactobacillus paracasei, and Lactobacillus salivarius. These are live beneficial bacteria meant to support gut and digestive health.

The product also contains trans-gluco-oligosaccharides as an inactive ingredient (a carbohydrate that feeds the probiotics).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive health and immune support for infants.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Necrotizing enterocolitis (NEC), Neonatal jaundice, Prematurity — and 3 related terms.
  • The strongest evidence on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Colic.
  • Also on file: Bifidobacterium Animalis Subsp. Lactis is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Necrotizing enterocolitis (NEC), Rotaviral diarrhea, Prematurity, and more.

The Bifidobacterium animalis subsp. lactis in this product is possibly effective for respiratory tract infections, irritable bowel syndrome (IBS), and constipation, based on the evidence we have. Bifidobacterium bifidum is possibly effective for IBS and respiratory tract infections, but the data on hay fever, Alzheimer disease, and anxiety isn't established enough to rate.

For the Lactobacillus species in the blend, we don't have effectiveness ratings on file.

The evidence, ingredient by ingredient Bifidobacterium Animalis Subsp. Lactis Bifidobacterium Bifidum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both Bifidobacterium species in this product are generally well tolerated by most healthy people when taken as directed. The most commonly reported side effect is diarrhea, and some people have reported bloating, flatulence, abdominal pain, constipation, or stomach burn — though these are uncommon.

In rare cases, probiotics have caused infections in people with weakened immune systems, so if that applies to you, check with your doctor first. One case of rash with itching was reported in a study, but it's unclear whether it was caused by this probiotic or something else.

For pregnancy, Bifidobacterium bifidum is rated possibly safe; we don't have pregnancy or lactation data on file for the other ingredients, so talk with your doctor if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Bifidobacterium Animalis Subsp. Lactis Bifidobacterium Bifidum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Bifidobacterium Animalis Subsp. Lactis, Bifidobacterium Bifidum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you're taking antibiotic drugs, separate them from this product by several hours — the antibiotics can kill the live organisms and make the probiotic less effective. Ask your pharmacist how long to wait between doses based on which antibiotic you're on.

No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

HLC Baby B is a multi-strain probiotic powder that may help with gut health, IBS, respiratory health, and constipation — though the evidence is strongest for IBS and infections. The main thing to watch for is antibiotics: space them several hours apart from this product so the antibiotics don't kill off the live bacteria.

If you're on antibiotics, have a weakened immune system, or are pregnant or breastfeeding, talk with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about HLC Baby B, straight from the product label.

Brand Pharmax
Barcode (UPC) 88319621670
Net contents 0.2 oz.; 6 Gram(s)
Market status On market
Date entered into DSLD Sep 22, 2016
DSLD ID 64324
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for HLC Baby B by Pharmax, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Children less than 4 years of age
Minimum serving Sizes:
0.2 Gram(s)
Maximum serving Sizes:
0.2 Gram(s)
Servings per container
30
UPC/BARCODE
88319621670
IngredientAmount% DV
Lactobacillus paracasei (CUL-08)0 NP--
Bifidobacterium animalis subsp. lactis (CUL-34)0 NP--
HLC Consortium0 NP--
Bifidobacterium bifidum (CUL-20)0 NP--
Lactobacillus salivarius (CUL-61)0 NP--

Other ingredients: trans-Gluco-oligosaccharides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended intake: Children (1-4 years): In a glass, add water or milk to one scoop of HLC Baby B and mix. Take once daily with a meal, at least 2-3 hours before or after taking antibiotics, or as professionally directed.

Precautions

Risk Information: If you have an immune-compromised condition, do not use. If you are experiencing fever, vomiting, bloody diarrhea or severe abdominal pain, consult your healthcare practitioner prior to use. If symptoms of digestive upset occur, worsen or persist beyond three days, discontinue use and consult your healthcare practitioner.

Keep out of reach of children.

Contains: milk

Vacuum-sealed for your protection and for product freshness. Do not use if outer seal is missing or broken.

Keep out of reach of children.

General Statements

Safety-sealed for your protection and for product freshness.

Research driven strains

Human Lactic Commensals (HLC) probiotic strains were studied in a randomized, double-blind, placebo-controlled human trial at 10 billion CFU per day. Proprietary non-pathogenic human-sourced microflora bacterial strains are utilized as they have strong epithelial adherence and a naturally high tolerance to stomach acid.

For risk information, see outer box.

Pack size:

Storage

Store under refrigeration (below 46(0) F).

Store under refrigeration (below 46(0)F).

FDA Statement of Identity

probiotic supplement

Formula

for breast fed babies

Contains: milk

General

V1.0 Code PB28-6

Formulation

Gluten free and FOS free

Seals/Symbols

Gluten free and FOS free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

HLC Baby B by Pharmax label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

HLC Baby B label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in HLC Baby B by Pharmax

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.2 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

HLC Consortium

0 NP per serving

Other (inactive) ingredients: Trans-Gluco-oligosaccharides. These complete the product’s ingredient list but are not active constituents.

Interaction report

HLC Baby B by Pharmax Drug Interactions

Want to check YOUR meds against HLC Baby B?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bifidobacterium animalis subsp. lactis (CUL-34) 182
Bifidobacterium bifidum (CUL-20) 182

Individual Drug Interactions

The ingredients in HLC Baby B interact with 182 drugs. Click any drug to see the details.

2 of the 4 ingredients in HLC Baby B interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium animalis subsp. lactis (CUL-34) Bifidobacterium bifidum (CUL-20)

Each ingredient & the kinds of drugs it affects

For each ingredient in HLC Baby B with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium animalis subsp. lactis (CUL-34)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium lactis with antibiotic drugs might decrease the effectiveness of B. lactis.
Since B. lactis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. lactis preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium animalis subsp. lactis (CUL-34) full monograph & interactions

Bifidobacterium bifidum (CUL-20)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium bifidum (CUL-20) full monograph & interactions
The maker

Brand information

Manufacturer and brand details for HLC Baby B, from the product label.

Pharmax

See all Pharmax products
Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

HLC Baby B by Pharmax: Common Questions

Does HLC Baby B by Pharmax interact with any medications?
Yes. Based on its ingredients, HLC Baby B has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
HLC Baby B contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What do the bacteria in HLC Baby B actually do?
They're live, beneficial bacteria meant to support your gut health and digestion. The two main strains are Bifidobacterium animalis subsp. lactis and Bifidobacterium bifidum, which research suggests may help with irritable bowel syndrome, respiratory health, and constipation.
Can I take this with an antibiotic?
You can, but not at the same time. The antibiotic will kill the live bacteria in the probiotic. Space your doses several hours apart — your pharmacist can tell you the exact timing based on which antibiotic you're on.
What side effects should I watch for?
Most people tolerate it well. The most common side effect is diarrhea; some also report bloating, gas, or stomach discomfort. These are usually mild and uncommon. Rash has been reported very rarely in clinical studies, though it's not clear it was caused by the probiotic itself.
Is this safe for a baby with a weakened immune system?
Probiotics can theoretically cause infections in people with severely weakened immune systems, which is rare but a real concern. If your baby has immune issues, talk with your pediatrician or pharmacist before starting this product.
Is it safe to use while breastfeeding or if I'm pregnant?
We have limited data on this. Bifidobacterium bifidum is rated possibly safe in pregnancy, but we don't have pregnancy or lactation information on file for the other ingredients. Talk with your doctor or pharmacist for personalized advice based on your situation.
What's in the powder besides the bacteria?
The powder contains live probiotic bacteria and trans-gluco-oligosaccharides, which is a carbohydrate that feeds the probiotics. There are no other fillers or additives listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

HLC Baby B label
Go deeper

The Full Monographs Behind HLC Baby B’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bifidobacterium Animalis Subsp. Lactis

Interacts with 182 drugs

Bifidobacterium animalis subsp. lactis is a well-studied probiotic bacterium commonly added to supplements and yogurts to support digestion and gut health. It appears generally safe for most...

Read the full Bifidobacterium Animalis Subsp. Lactis monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph →
Sources

Sources & How We Checked

HLC Baby B's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Animalis Subsp. Lactis 8 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Phuapradit P, Varavithya W, Vathanophas K, et al. Reduction of rotavirus infection in children receiving bifidobacteria-supplemented formula. J Med Assoc Thai 1999;82:S43-8.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  5. Taipale TJ, Pienihäkkinen K, Isolauri E, Jokela JT, Söderling EM. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in early childhood. Pediatr Res. 2016;79(1-1):65-9. PubMed
  6. Amat-Bou M, Garcia-Ribera S, Climent E, et al. Effects of Bifidobacterium animalis Subsp. lactis (BPL1) supplementation in children and adolescents with prader-willi syndrome: A randomized crossover trial. Nutrients. 2020;12(10):3123. PubMed
  7. Mäkelä SM, Forssten SD, Kailajärvi M, et al. Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti-inflammatory drug: A randomized, placebo-controlled, double-blind clinical trial. Br J Clin Ph
  8. Wildt S, Munck LK, Vinter-Jensen L, et al. Probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis. Inflamm Bowel Dis 2006;12(5):395-401. PubMed

See these in context on the Bifidobacterium Animalis Subsp. Lactis monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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