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Dietary supplement

Holy Basil Ingredients & Drug Interactions

by Eclectic Herb

Holy Basil label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Holy Basil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Holy Basil is a dietary supplement by Eclectic Herb with 1 active ingredient. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Holy Basil, Freeze-Dried, Fresh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Holy Basil by Eclectic Herb

Ask about any prescription or over-the-counter medication and we check it for interactions with Holy Basil by Eclectic Herb — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Holy Basil by Eclectic Herb

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: holy basil, freeze-dried from the fresh plant. The capsules also contain hypromellose, an inactive ingredient used in the capsule shell.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Holy Basil product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Holy Basil's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“antioxidant support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence on holy basil isn't established in the data we hold. It's been studied for generalized anxiety, asthma, headaches, respiratory infections, dental plaque, and diabetes, but the data on file rates all of these as having insufficient reliable evidence to rate — meaning we don't have enough high-quality research to say whether it works.

The evidence, ingredient by ingredient Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Holy basil extract is generally well tolerated in the short term, but good long-term safety data are limited. The most common side effects are loose stools and nausea when taken by mouth — a small number of trial participants reported these.

Topically, it can leave a bitter taste. During pregnancy, the safety data advises against it — animal data raise concerns and human safety isn't established.

The same applies to breastfeeding; there isn't enough reliable information to know either way, so talk with your doctor or pharmacist before using it.

Side effects, ingredient by ingredient Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on blood thinners (anticoagulants or antiplatelets), diabetes medications, or the barbiturate pentobarbital — all carry Moderate interaction risks with holy basil.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Holy basil might appeal to someone looking for natural support for anxiety or blood sugar, but the evidence for effectiveness isn't established yet. If you take blood thinners, diabetes medications, or sedatives like pentobarbital, you'll want to check with your doctor or pharmacist first — the interactions are theoretical but real enough to warrant a conversation.

Talk it over with your own healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Holy Basil, straight from the product label.

Brand Eclectic Herb
Barcode (UPC) 023363309733
Net contents 90 Veg Cap(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 294695
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Holy Basil by Eclectic Herb, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
90
UPC/BARCODE
023363309733
IngredientAmount% DV
Holy Basil, Freeze-Dried, Fresh200 mg--

Other ingredients: Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Antioxidant Whole herbs

Holy Basil 500 mg

100% Kosher

Formulation

Raw Naturally concentrated US grown

Gluten Free Non GMO

Vegan

Freeze dried fresh for peak plant power Freeze-drying is the best method of preservation as it naturally concentrates the nutrients in the plan by removing only the water.

Nothing artificial - no fillers are additives.

Concentrated 9 X through freeze-drying

General Statements

Our aronia berries are locally grown and fresh freeze-dried in-house in small batches. @eclecticherb

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 1-3 capsules per day.

Precautions

Keep out of reach of children. Consult your health care advisor regarding herbs with pregnancy, infants or prescription drugs.

Discontinue use if unusual symptoms occur.

Consult your health care advisor regarding herbs with pregnancy, infants or prescription drugs.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Holy Basil by Eclectic Herb label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Holy Basil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Holy Basil by Eclectic Herb

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Holy Basil, Freeze-Dried, Fresh

Interacts with
212 drugs
200 mg per serving Form: Ocimum sanctum, Freeze-Dried, Fresh

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and p...

Holy Basil, Freeze-Dried, Fresh monograph & interactions

Other (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Holy Basil by Eclectic Herb Drug Interactions

Want to check YOUR meds against Holy Basil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

Holy Basil, Freeze-Dried, Fresh 212

Individual Drug Interactions

The ingredients in Holy Basil interact with 212 drugs. Click any drug to see the details.

1 of the 1 ingredient in Holy Basil interact with drugs. Each result below shows which ingredient is responsible. Holy Basil, Freeze-Dried, Fresh

Each ingredient & the kinds of drugs it affects

For each ingredient in Holy Basil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Holy Basil, Freeze-Dried, Fresh3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Holy Basil, Freeze-Dried, Fresh full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Holy Basil, from the product label.

Eclectic Herb

See all Eclectic Herb products
Name
Eclectic Herb
Street Address
755 NE 6th St.
City
Gresham
State
Oregon
ZipCode
97030
Phone Number
503.668.4120
Web Address
www.eclecticherb.com
Pharmacist Counseling Corner

Holy Basil by Eclectic Herb: Common Questions

Does Holy Basil by Eclectic Herb interact with any medications?
Yes. Based on its ingredients, Holy Basil has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Holy Basil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is holy basil safe to take if I'm pregnant or breastfeeding?
No — the safety data advises against it in pregnancy because animal studies raise concerns and human safety isn't established. If you're breastfeeding, there also isn't enough reliable information to know either way. Talk with your doctor or pharmacist for personalized advice before using it.
What side effects should I expect?
Holy basil is generally well tolerated, and side effects are uncommon. When they do occur, the most common are loose stools and nausea by mouth — only a small number of trial participants experienced these. If applied to your gums or mouth, it can leave a bitter taste.
Does holy basil actually work for anxiety or blood sugar?
The evidence we hold rates it as having insufficient reliable data to say — there's research interest, but not enough high-quality studies yet to call it effective for anxiety, diabetes, or the other conditions it's been studied for.
Are there any other ingredients in this capsule besides holy basil?
No active ingredients — just the holy basil itself. The capsule shell is made with hypromellose, an inert ingredient used in most capsules.
How long has holy basil been studied for safety?
Short-term use appears well tolerated, but good long-term safety data are limited. If you're considering this long-term, that's another reason to check in with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Holy Basil label
Go deeper

The Full Monographs Behind Holy Basil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph →
Sources

Sources & How We Checked

Holy Basil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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