Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Immune Balance Ingredients & Drug Interactions

by Country Life Gut Connection

Immune Balance label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Immune Balance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Immune Balance is a dietary supplement by Country Life Gut Connection with 3 active ingredients. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wellmune. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Immune Balance by Country Life Gut Connection

Ask about any prescription or over-the-counter medication and we check it for interactions with Immune Balance by Country Life Gut Connection — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Immune Balance by Country Life Gut Connection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has three active ingredients: EpiCor, PreticX, and Wellmune. Wellmune is a source of beta-glucans, a type of fiber that comes from yeast and is studied for immune and heart health support.

The inactive ingredients in the capsule are cellulose, rice bran extract, vegetable glaze, sunflower oil, and silica — standard binders and fillers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: improve digestive health and immune balance.
  • We looked for evidence on: Inflammatory bowel disease (IBD), Irritable bowel syndrome (IBS), Upper respiratory tract infection (URTI), Lower respiratory tract infections, Exercise-induced respiratory infections, Wound healing — and 3 related terms.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI) (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Inflammatory bowel disease (IBD), Exercise-induced respiratory infections, Lower respiratory tract infections, Irritable bowel syndrome (IBS), and more.

Wellmune (beta-glucans) is rated Likely Effective for two conditions: high cholesterol (dyslipidemia) and coronary heart disease. The evidence supports its use for these cardiovascular concerns.

We don't have effectiveness ratings on file for EpiCor or PreticX, so we can't speak to what those ingredients do or how well they work.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food are generally well tolerated by most people. However, concentrated supplements like this one lack detailed safety data, so caution is advised — don't take more than directed.

In one trial, topical beta-glucans cream caused mild, self-limiting skin reactions in about 27% of people. Oral beta-glucans are usually well tolerated, though one case of temporary liver enzyme elevation was reported in a child at a very high dose.

We don't have enough data on beta-glucans in supplement doses during pregnancy or breastfeeding. If you're pregnant or nursing, talk with your doctor or pharmacist before starting this product.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take antihypertensive drugs (blood pressure medications) or immunosuppressants. Both have Moderate interactions with Wellmune in this product.

For EpiCor and PreticX, we hold no interaction data, so we can't flag specific drug types — but your pharmacist can search your exact prescriptions using the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with cholesterol and heart health if Wellmune's effects are what you're after. If you take blood pressure medications or drugs that suppress your immune system, you'll need to check with your pharmacist first — the interactions are real.

EpiCor and PreticX aren't checkable for drug interactions, so bring your medication list in.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Immune Balance, straight from the product label.

Brand Country Life Gut Connection
Barcode (UPC) 015794030140
Net contents 60 Vegan Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 333236
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Immune Balance by Country Life Gut Connection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
015794030140
IngredientAmount% DV
EpiCor630 mg--
PreticX200 mg--
Wellmune250 mg--

Other ingredients: Cellulose, Rice Bran Extract, Vegetable Glaze, Sunflower Oil, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Digestivebalance Sleepbalance Weightbalance Cognitivebalance Immunebalance Moodbalance Stressbalance It's all connected. Good digestion starts in the gut, but so does a good mood, a healthy immune system, energy levels and sleep.

3014BX09E22TL 030140 For more information on EpiCor and on Country Life's Gut Connection Go to CountryLifeVitamins.com

Yes recyclable packaging

Formulation

Gut Connection by Country Life is a scientifically formulated range of supplements that connects the gut to individual health issues that matter.

Good health starts in your gut. Gut Connection Immune Balance by Country Life is specially and scientifically formulated to help improve your digestive health.

This product has been manufactured at a GMP Registered facility.

Each daily serving will improve your gut and your health - it's all connected. A healthy gut has more than 10 trillion bacteria! Gut Connection is different because it does not provide probiotics, so you can take it alone or with your favorite probiotic. This allows your body to create its own healthy bacteria. Money Back Guarantee You'll love it. If not completely satisfied, request a refund within 60 days of purchase. See details at www.GutConnectionRebate.com or call 877-322-8255.

Certified Gluten Free GFCO.org

Probiotic free

Improves gut microbiome health Supports a strong, healthy immune system Reinforces the immune system's first line of defense

Our pledge of integrity Authenticity - Cleanliness - Freshness Consistency - Accuracy

Yes certified gluten-free by GFCO.org No GMOs No wheat, soy or milk No salt, sugar or preservatives No artificial colors, flavors or sweeteners No magnesium stearate

Yes certified vegan by the AVA

Yes manufacturing supports wind power

Formula

Our clinically tested ingredients together are "Balanced Inside" for your digestive health. EpiCor helps maintain good digestive and immune health. PreticX helps feed the probiotics in your gut. Wellmune helps the body maintain good health in times of stress.

Gut Connection contains 630 mg of clinically researched EpiCor, why? EpiCor Helps maintain the gut lining Maintains gut barrier function Stimulates healthy bacteria in the gut Supports overall gut microbiome Supports healthy shift in gut microbiota composition Based on results from a study using a dynamic model representing GI digestion. EpiCor is a whole food fermented prebiotic that balances and strengthens your gut by boosting its levels of good bacteria to promote health every day. Made using a fermented whole food yeast (Saccharomyces cerevisiae), it captures a complex array of beneficial nutrients through the process of fermentation.

KOF-K Parve (Kosher)

Yes kosher-parve

Seals/Symbols

Certified B Corporation Certified Gluten Free GFCO.org KOF-K Parve (Kosher)

Clinically studied ingredients

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take two (2) capsules daily with food. As a reminder, discuss the supplements and medications that you take with your health care providers.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution: If you are pregnant, nursing, or taking medication, have a medical condition or planning surgery, consult a doctor before using this product.

Stop using and consult a doctor if any adverse reactions occur. Do not accept if seal is broken.

Keep out of the reach of children.

Storage

Store in a dry place between 59 degrees - 86 degrees F.

Brand IP Statement(s)

EpiCor is a registered trademark of Embria Health Sciences, LLC PreticX is a trademark of AIDP Inc. Wellmune is a registered trademark of Kerry Group. Copyright 2022 Country Life

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Immune Balance by Country Life Gut Connection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Immune Balance label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Immune Balance by Country Life Gut Connection

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

EpiCor

630 mg per serving Form: Yeast Fermentate, Dried

PreticX

200 mg per serving Form: Xylo-oligosaccharides

Wellmune

Interacts with
293 drugs
250 mg per serving Form: Baker's Yeast Beta Glucan

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Wellmune monograph & interactions

Other (inactive) ingredients: Cellulose, Rice Bran Extract, Vegetable Glaze, Sunflower Oil, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Immune Balance by Country Life Gut Connection Drug Interactions

Want to check YOUR meds against Immune Balance?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Wellmune 293

Individual Drug Interactions

The ingredients in Immune Balance interact with 293 drugs. Click any drug to see the details.

1 of the 3 ingredients in Immune Balance interact with drugs. Each result below shows which ingredient is responsible. Wellmune

Each ingredient & the kinds of drugs it affects

For each ingredient in Immune Balance with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wellmune2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Wellmune full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Immune Balance, from the product label.

Country Life Gut Connection

See all Country Life Gut Connection products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

Immune Balance by Country Life Gut Connection: Common Questions

Does Immune Balance by Country Life Gut Connection interact with any medications?
Yes. Based on its ingredients, Immune Balance has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Immune Balance contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product actually lower cholesterol?
Wellmune, one of the three ingredients, is rated Likely Effective for high cholesterol. The other two ingredients don't have effectiveness data on file with us, so we can't speak to their contribution.
What's Wellmune?
Wellmune is beta-glucans, a type of soluble fiber derived from yeast. It's studied for supporting immune function and cardiovascular health, and the evidence supports its use for cholesterol and heart disease.
Are there any side effects from taking this?
Beta-glucans are generally well tolerated when taken by mouth. We have very limited safety data on these concentrated supplement doses, so stick to the recommended amount. One case of temporary liver enzyme elevation was reported at a very high dose in a child.
Can I take this while pregnant or breastfeeding?
We don't have enough research data on supplement doses of beta-glucans during pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether this is right for you — that's an individual call based on your health situation.
What do the inactive ingredients do?
They're fillers and binders that help form and stabilize the capsule: cellulose, rice bran extract, vegetable glaze, sunflower oil, and silica. They don't have a therapeutic role.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Immune Balance is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Immune Balance label
Go deeper

The Full Monographs Behind Immune Balance’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Immune Balance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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