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Dietary supplement

Inositol 1000 mg Ingredients & Drug Interactions

by Advanced Nutrition by Zahler

Inositol 1000 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Inositol 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Inositol 1000 mg is a dietary supplement by Advanced Nutrition by Zahler with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Inositol 1000 mg by Advanced Nutrition by Zahler

Ask about any prescription or over-the-counter medication and we check it for interactions with Inositol 1000 mg by Advanced Nutrition by Zahler — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Inositol 1000 mg by Advanced Nutrition by Zahler

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: inositol at 1000 mg per capsule. Inositol is a naturally occurring compound involved in cell signaling and insulin metabolism.

The capsule also holds two inactive ingredients (hypromellose and rice hull concentrate), which are fillers and capsule materials that play no therapeutic role.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Inositol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Nervous system and neurotransmitter function support.
  • We looked for evidence on: Anxiety, Panic disorder, Depression, Obsessive-compulsive disorder (OCD), Post-traumatic stress disorder (PTSD), Bipolar disorder — and 2 related terms.
  • The closest evidence on file: Inositol is rated "Possibly Ineffective" for Anxiety (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Ineffective" for Depression.
  • Also on file: Inositol is rated "Insufficient Reliable Evidence To Rate" for Bipolar disorder, Obsessive-compulsive disorder (OCD), Panic disorder, Post-traumatic stress disorder (PTSD).

Inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome. It is also possibly effective for reducing the risk of preterm labor.

The evidence is not established—or is possibly ineffective—for anxiety, diabetic nerve damage (diabetic neuropathy), and depression. If you're considering this supplement for one of those conditions, talk with your doctor about whether the current evidence supports it for your situation.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated at typical doses. The most common side effects when taken by mouth are mild: diarrhea, gas, and nausea.

In one small study, children who took inositol combined with omega-3 fatty acids reported cold and allergy symptoms, though it's unclear whether inositol was the cause. Pregnancy safety is not fully established; inositol is rated possibly safe in pregnancy, but use should be under medical supervision only.

There is not enough reliable data on safety during breastfeeding, so check with your doctor or pharmacist before taking it if you are nursing.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any antidiabetes drugs (such as insulin, metformin, or sulfonylureas). Inositol can lower blood sugar, so combining it with diabetes medication may increase the risk of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement may be worth considering if you have PCOS, metabolic syndrome, or are at risk for preterm labor—talk with your doctor about whether it fits your needs. If you take any diabetes medication, you'll want to review this product with your pharmacist or doctor first, since inositol lowers blood sugar.

Pregnancy and breastfeeding use requires medical supervision.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Inositol 1000 mg, straight from the product label.

Brand Advanced Nutrition by Zahler
Barcode (UPC) 848998082529
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 301100
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Inositol 1000 mg by Advanced Nutrition by Zahler, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
848998082529
IngredientAmount% DV
Inositol1000 mg--

Other ingredients: Hypromellose, Rice hull concentrate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Nervous System Support Formula Zahler Inositol supports healthy nerve & neurotransmitter functions. In addition, Inositol participates in the metabolism of fats in the liver as well as supports insulin function in glycogen storage and utilization, thereby making glucose readily available for cellular energy requirements.

Kosher Pareve D OU Kosher Under the strict supervision of Rabbi SH. Stern & The Orthodox Union

General Statements

You may need additional supplements to support a healthy diet, consult your nutritionist for a formula that is right for you or contact us at 877-ASK-ZAHLER (877-275-9245) or [email protected].

Precautions

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

If pregnant, nursing or on medication, consult with your healthcare practitioner.

FDA Disclaimer Statement

These statements have not been evaluated by the Food ad Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Kosher Pareve D OU Kosher This product is manufactured in a GMP Certified Facility

Manufactured in the USA

Formulation

Non-GMO Gluten free Dairy free Soy free

Vegetarian friendly

Mood and nervous system support Promotes liver function and cellular health General health

Storage

Store tightly closed in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Feel Better, Everyday

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule daily with food, or as directed by your healthcare practitioner.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Inositol 1000 mg by Advanced Nutrition by Zahler label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Inositol 1000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Inositol 1000 mg by Advanced Nutrition by Zahler

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Inositol

Interacts with
86 drugs
1000 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

Other (inactive) ingredients: Hypromellose, Rice hull concentrate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Inositol 1000 mg by Advanced Nutrition by Zahler Drug Interactions

Want to check YOUR meds against Inositol 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Inositol 86

Individual Drug Interactions

The ingredients in Inositol 1000 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Inositol 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Inositol 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Inositol 1000 mg, from the product label.

Advanced Nutrition by Zahler

See all Advanced Nutrition by Zahler products
Name
Advanced Nutrition by Zahler
City
New Milford
State
NJ
ZipCode
07646
Web Address
www.zahlers.com
Pharmacist Counseling Corner

Inositol 1000 mg by Advanced Nutrition by Zahler: Common Questions

Does Inositol 1000 mg by Advanced Nutrition by Zahler interact with any medications?
Yes. Based on its ingredients, Inositol 1000 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Inositol 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does inositol really help with PCOS?
Inositol is possibly effective for PCOS based on available research. It's also possibly effective for metabolic syndrome. If you have PCOS or think you might, talk with your doctor about whether adding this supplement makes sense for you.
What are the most common side effects?
Diarrhea, gas, and nausea are the most common side effects when inositol is taken by mouth. They are usually mild. If you experience any of these, consider taking the supplement with food or reducing the dose.
Can I take this if I'm pregnant?
Inositol is rated possibly safe in pregnancy, but the safety data is not fully established. If you're pregnant or planning to become pregnant, talk with your doctor or pharmacist before taking it—they can weigh the potential benefit against the uncertainty.
Is it safe to breastfeed while taking inositol?
There isn't enough reliable information to know either way. Talk with your doctor or pharmacist before taking this supplement if you're breastfeeding.
Will inositol help my depression or anxiety?
The evidence does not support inositol for depression or anxiety—it's rated possibly ineffective for both. If you're dealing with depression or anxiety, work with your doctor on treatments with stronger evidence behind them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Inositol 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Inositol 1000 mg label
Go deeper

The Full Monographs Behind Inositol 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Inositol 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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