Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Iris Ver. Blue Flag Ingredients & Drug Interactions

by Wise Woman Herbals

Iris Ver. Blue Flag label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Iris Ver. Blue Flag against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Iris Ver. Blue Flag is a dietary supplement by Wise Woman Herbals with 1 active ingredient. Its ingredients are commonly taken for skin conditions like acne and eczema, constipation and digestive complaints, liver and gallbladder support (traditional).Based on those ingredients, 78 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Blue Flag. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Iris Ver. Blue Flag by Wise Woman Herbals

Ask about any prescription or over-the-counter medication and we check it for interactions with Iris Ver. Blue Flag by Wise Woman Herbals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Iris Ver. Blue Flag by Wise Woman Herbals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.30 mL) without saying how much of each component you get.

Iris Ver. Blue Flag is a liquid herbal product containing one active ingredient: blue flag root.

The product also contains water and alcohol as inactive ingredients to preserve and carry the herb.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Blue Flag product and its label doesn't state a use — see Blue Flag's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for blue flag in our records, so we can't tell you whether this product is proven to work for any particular purpose.

The evidence, ingredient by ingredient Blue Flag

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blue flag can cause nausea, vomiting, and irritation of mucous membranes — the fresh root is especially likely to irritate. The volatile oils in blue flag can also trigger headache, eye inflammation, throat irritation, and watery eyes.

The safety data advises against using blue flag during pregnancy because of potential toxicity and lack of safety information. It is also not safe while breastfeeding — the data shows it is likely unsafe in that situation.

Side effects, ingredient by ingredient Blue Flag

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blue Flag.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications.
  • For scale: 78 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Iris Ver. Blue Flag, double-check if you're on heart medications like digoxin (a Major interaction), water pills or blood thinners like warfarin (both Moderate).

If you take any prescription drugs, use the medication checker below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Blue flag is an herbal stimulant laxative that interacts with heart medications, water pills, and blood thinners. If you take any of those drugs, or any prescription medication at all, check with your pharmacist before starting.

Because of pregnancy and breastfeeding concerns, talk to your doctor or pharmacist if either applies to you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Iris Ver. Blue Flag, straight from the product label.

Brand Wise Woman Herbals
Barcode (UPC) 748840010550
Net contents 2 Fluid oz.; 60 mL
Market status On market
Date entered into DSLD May 24, 2023
DSLD ID 284855
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Iris Ver. Blue Flag by Wise Woman Herbals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
5 Drop(s)
Servings per container
240
UPC/BARCODE
748840010550
IngredientAmount% DV
Proprietary Blend0.3 mL--
Blue Flag0 NP--

Other ingredients: Water, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Shake well. Add 1-5 drops to water, 1-3 times per day.

Formulation

The presence of particulate matter in this product is normal.

Precautions

Caution: Not recommended during pregnancy.

Keep out of the reach of children.

General Statements

Professional formula

FDA Statement of Identity

Dietary supplement

Storage

Store in a cool, dry area away from direct sunlight with the lid tightly sealed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Iris Ver. Blue Flag by Wise Woman Herbals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Iris Ver. Blue Flag label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Iris Ver. Blue Flag by Wise Woman Herbals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container240 Amounts shown are per serving.

Proprietary Blend

0.3 mL per serving

Other (inactive) ingredients: Water, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Iris Ver. Blue Flag by Wise Woman Herbals Drug Interactions

Want to check YOUR meds against Iris Ver. Blue Flag?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
78Drugs
1 Major 77 Moderate

Ingredients driving the most interactions

Blue Flag 78

Individual Drug Interactions

The ingredients in Iris Ver. Blue Flag interact with 78 drugs. Click any drug to see the details.

1 of the 1 ingredient in Iris Ver. Blue Flag interact with drugs. Each result below shows which ingredient is responsible. Blue Flag

Each ingredient & the kinds of drugs it affects

For each ingredient in Iris Ver. Blue Flag with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blue Flag3 drug types · 78 drugs

Digoxin (Lanoxin)

Theoretically, overuse or abuse of this product increases the risk of adverse effects from cardiac glycoside drugs.

Likelihood Probable Evidence D
Diuretic Drugs

Overuse of blue flag might compound diuretic-induced potassium loss. There is some concern that people taking blue flag along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Blue flag has stimulant laxative effects. In some people blue flag can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of blue flag.

Likelihood Possible Evidence D
Blue Flag full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Iris Ver. Blue Flag, from the product label.

Wise Woman Herbals

See all Wise Woman Herbals products
Name
Wise Woman Herbals
City
Creswell
State
OR
ZipCode
97426
Phone Number
541.895.5152
Web Address
wisewomanherbals.com
Pharmacist Counseling Corner

Iris Ver. Blue Flag by Wise Woman Herbals: Common Questions

Does Iris Ver. Blue Flag by Wise Woman Herbals interact with any medications?
Yes. Based on its ingredients, Iris Ver. Blue Flag has a known interaction with 78 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Iris Ver. Blue Flag contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
No. The safety data advises against blue flag during pregnancy because of potential toxicity and lack of safety data. Talk with your doctor or pharmacist about what's right for you.
Is it safe to breastfeed while taking this?
No. The data shows blue flag is likely unsafe while breastfeeding. Speak with your pharmacist or doctor if you're nursing and interested in herbal products.
What side effects might I notice?
Nausea, vomiting, and irritation of the mouth and throat are possible. The volatile oils can also cause headache, eye inflammation, and watery eyes. The fresh root is especially likely to irritate.
Why can't I take this with water pills?
Blue flag can cause diarrhea and has stimulant laxative effects. Diarrhea combined with the potassium loss that diuretics already cause can dangerously lower your potassium level, so the two together require caution.
What does blue flag do?
Blue flag is an herbal laxative — it stimulates bowel movements. We don't hold effectiveness data showing what conditions it's proven to treat.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Iris Ver. Blue Flag is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Iris Ver. Blue Flag label
Go deeper

The Full Monographs Behind Iris Ver. Blue Flag’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blue Flag

Interacts with 78 drugs

Blue Flag is a flowering plant whose root has been used in traditional and herbal medicine for skin and digestive complaints, but there is very little modern scientific evidence to support t...

Read the full Blue Flag monograph →
Sources

Sources & How We Checked

Iris Ver. Blue Flag's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blue Flag 3 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Blue Flag monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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