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Dietary supplement

Jiaogulan Extract 820 mg Ingredients & Drug Interactions

by We Like Vitamins

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Jiaogulan Extract 820 mg is a dietary supplement by We Like Vitamins with 1 active ingredient. Its ingredients are commonly taken for fatigue and stress (adaptogen), blood sugar support, high blood pressure.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Jiaogulan Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Jiaogulan Extract 820 mg by We Like Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: jiaogulan leaf extract at 820 mg per capsule. The capsule also holds gelatin and rice powder as inactive ingredients (fillers and binders to hold the capsule together).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support healthy glucose levels and appetite control.
  • We looked for evidence on: Diabetes, Obesity, Metabolic syndrome, Insulin resistance.
  • The strongest evidence on file: Jiaogulan is rated "Possibly Effective" for Diabetes (Natural Medicines).
  • Also on file: Jiaogulan is rated "Insufficient Reliable Evidence To Rate" for Obesity.

Jiaogulan is possibly effective for diabetes—clinical research shows it can lower blood sugar levels. For athletic performance, cardiovascular disease, cancer, nonalcoholic fatty liver disease, and respiratory tract infections, we don't have enough reliable evidence to say whether it works or not.

The evidence, ingredient by ingredient Jiaogulan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Jiaogulan is generally well tolerated when taken as a tea or supplement for short periods, but we don't have solid data on long-term safety. In trials lasting up to 4 months, the most common side effects were diarrhea and nausea; some people also reported dry mouth, dizziness, and insomnia.

The safety data advises against taking jiaogulan during pregnancy or while breastfeeding because there isn't enough information to know it's safe for you or your baby.

Side effects, ingredient by ingredient Jiaogulan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Jiaogulan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs—jiaogulan may raise bleeding risk. Also flag it if you take diabetes medications (risk of low blood sugar) or immunosuppressants (it may reduce their effectiveness).

No interactions are documented in our data for other medication types.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Jiaogulan might be worth considering if you're interested in blood sugar support and you don't take blood thinners, diabetes medications, or immunosuppressants. If you do take any of those, or if you're pregnant, trying to become pregnant, or breastfeeding, talk with your doctor or pharmacist before starting it.

Because this supplement can affect how your medications work, check with your own healthcare provider before adding it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Jiaogulan Extract 820 mg, straight from the product label.

Brand We Like Vitamins
Barcode (UPC) X0020AOG1N
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jan 22, 2022
DSLD ID 259113
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Jiaogulan Extract 820 mg by We Like Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
X0020AOG1N
IngredientAmount% DV
Jiaogulan Leaf Extract820 mg--

Other ingredients: Gelatin, Rice powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: For adults, take two (2) capsules daily, preferably with a meal or as directed by a healthcare professional. Always discus all supplements with your health care provider.

Precautions

Warning: If you are pregnant, nursing, taking any medications, have or have had a health condition, or planning a medical procedure, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Store in a cool, dry place. Avoid excessive heat or moisture.

Formulation

Helps to support healthy glucose levels Helps to support appetite control

Zero: Preservatives, artificial colors, artificial flavors, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch, or wheat.

FDA Statement of Identity

Dietary Supplement

General Statements

Vitamin angels proud supporter Every bottle counts Every item you purchase from us helps to provide life-changing vitamins to a mother or child in need. Thank you!

See for yourself

Jiaogulan Extract 820 mg by We Like Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Jiaogulan Extract 820 mg by We Like Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Jiaogulan Leaf Extract

Interacts with
327 drugs
820 mg per serving

Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support. Early human and...

Jiaogulan Leaf Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Rice powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Jiaogulan Extract 820 mg by We Like Vitamins Drug Interactions

Want to check YOUR meds against Jiaogulan Extract 820 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Jiaogulan Extract 820 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Jiaogulan Leaf Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, jiaogulan might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research suggests that jiaogulan has antiplatelet effects.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, jiaogulan might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that jiaogulan can lower blood glucose levels.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, jiaogulan might decrease the effectiveness of immunosuppressive therapy.
Clinical and animal studies suggest that jiaogulan can stimulate the immune system.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Jiaogulan Extract 820 mg, from the product label.

We Like Vitamins

See all We Like Vitamins products
Name
We Like Vitamins
Street Address
7125 Headley St. #51
City
Ada
State
MI
ZipCode
49301
Web Address
welikevitamins.com
Pharmacist Counseling Corner

Jiaogulan Extract 820 mg by We Like Vitamins: Common Questions

Does Jiaogulan Extract 820 mg by We Like Vitamins interact with any medications?
Yes. Based on its ingredients, Jiaogulan Extract 820 mg has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Jiaogulan Extract 820 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data advises against jiaogulan during pregnancy because it may affect your developing baby, and there isn't enough information to know it's safe while breastfeeding. Talk with your doctor or pharmacist about alternatives if you're considering this supplement.
What are the most common side effects?
In studies up to 4 months long, diarrhea and nausea were the most common. Some people also reported dry mouth, dizziness, or insomnia. Most people tolerate it well for short-term use.
Does jiaogulan actually work for diabetes?
It's possibly effective—clinical research shows jiaogulan can lower blood sugar levels. But that's exactly why you need to check with your doctor or pharmacist before taking it with diabetes drugs; the combination could lower your blood sugar too much.
Is there enough evidence that it helps with athletic performance or heart health?
Not yet. We don't have reliable evidence to say whether jiaogulan works for athletic performance, cardiovascular disease, or several other conditions. The research just isn't there yet.
How long is it safe to take this?
Studies show jiaogulan is generally well tolerated for up to 4 months, but we don't have good data on long-term safety beyond that. If you're thinking about taking it longer, check in with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Jiaogulan Extract 820 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Jiaogulan Extract 820 mg label
Go deeper

The Full Monographs Behind Jiaogulan Extract 820 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Jiaogulan Extract 820 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Jiaogulan 8 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Tan H, Liu ZL, Liu MJ. [Antithrombotic effect of Gynostemma pentaphyllum]. Zhingguo Zhong Xi Yi Jie He Za Zhi 1993;13:278-80.
  3. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
  4. Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients. J Nutr Metab. 2013;2013:765383. doi: 10.1155/2013/765383.
  5. Li Y, Lin W, Huang J, Xie Y, Ma W. Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan). Chin Med. 2016 Sep 27;11:43. Review. PubMed
  6. Huyen VT, Phan DV, Thang P, Ky PT, Hoa NK, Ostenson CG. Antidiabetic effect of add-on Gynostemma pentaphyllum extract therapy with sulfonylureas in type 2 diabetic patients. Evid Based Complement Alternat Med 2012; 452313.
  7. Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients. Horm Metab Res. 2010;42(5):353-7.
  8. Rao A, Clayton P, Briskey D. The effect of an orally-dosed Gynostemma pentaphyllum extract (ActivAMP®) on body composition in overweight, adult men and women: a double-blind, randomised, placebo-controlled study. J Hum Nutr Diet 2021.

See these in context on the Jiaogulan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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