Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

KeepOnMovin' Peppermint Ingredients & Drug Interactions

by Oregon's Wild Harvest

KeepOnMovin' Peppermint label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking KeepOnMovin' Peppermint against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

KeepOnMovin' Peppermint is a dietary supplement by Oregon's Wild Harvest with 4 active ingredients. Its ingredients are commonly taken for irritable bowel syndrome (ibs), indigestion and gas, nausea.Based on those ingredients, 1,029 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are fresh FeverFew, Peppermint, fresh California Poppy. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against KeepOnMovin' Peppermint by Oregon's Wild Harvest

Ask about any prescription or over-the-counter medication and we check it for interactions with KeepOnMovin' Peppermint by Oregon's Wild Harvest — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of KeepOnMovin' Peppermint by Oregon's Wild Harvest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Biodynamic & Organic Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,190 mg) without saying how much of each component you get.

This liquid contains four active ingredients: peppermint, white willow, feverfew, and California poppy, all listed as fresh or biodynamic organic sources. Peppermint is the main flavor and contributes most of the anti-spasm and digestive support activity.

The other three are herbal botanicals traditionally used to support calm and ease discomfort. The product is delivered in a base of organic alcohol, glycerin, pear juice concentrate, and water — these are inactive ingredients (excipients) that carry and preserve the herbs.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: inflammation support.
  • We looked for evidence on: Anxiety, Dysmenorrhea, Irritable bowel syndrome (IBS), Migraine headache, Myalgia, Osteoarthritis — and 4 related terms.
  • The strongest evidence on file: Peppermint is rated "Likely Effective" for Irritable bowel syndrome (IBS) (Natural Medicines).
  • Also on file: California Poppy is rated "Insufficient Reliable Evidence To Rate" for Anxiety.
  • Also on file: Peppermint is rated "Insufficient Reliable Evidence To Rate" for Pre-procedural anxiety, Migraine headache, Myalgia, Osteoarthritis, and more.

Peppermint is likely effective for irritable bowel syndrome (IBS) and possibly effective for indigestion and nausea related to chemotherapy or medical procedures. Feverfew's evidence is less clear — our data shows insufficient evidence to rate its usefulness for tension headaches, arthritis, and other conditions it's traditionally used for.

California poppy has the same story: insufficient evidence for anxiety and insomnia. So while this blend targets digestive and nervous-system support, the strongest backing is for peppermint's effect on IBS.

The evidence, ingredient by ingredient Peppermint Feverfew California Poppy

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Peppermint is generally well tolerated when used as tea or in food amounts, though the concentrated oil in this liquid should be used carefully. The most common side effects are abdominal pain, belching, heartburn, diarrhea, and dry mouth.

Rare allergic reactions (including anaphylaxis) have been reported. Feverfew is generally well tolerated short-term, but chewing fresh leaves (as opposed to commercial preparations) raises the risk of mouth sores and tongue irritation.

Stopping feverfew after long-term use may cause rebound symptoms like anxiety and headaches. Feverfew should be avoided in pregnancy because it may stimulate the uterus, and there isn't enough data to support use while breastfeeding.

California poppy has limited safety data; the facts advise against it in pregnancy and lactation. Feverfew and California poppy haven't been thoroughly studied for long-term safety.

Side effects, ingredient by ingredient Peppermint Feverfew California Poppy

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — California Poppy, Peppermint, Feverfew.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 1,030 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on any of these: medications broken down by your liver's CYP3A4, CYP2C19, CYP2D6, CYP1A2, CYP2C9, or CYP2C8 enzyme systems (a large group including many blood pressure drugs, statins, and psychiatric medications); blood thinners or antiplatelet drugs like warfarin or aspirin; sleep aids and other sedating medications; or cyclosporine (an immunosuppressant). Peppermint, feverfew, or both may raise the levels of these drugs in your body.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

KeepOnMovin' Peppermint is most supported for digestive issues like IBS. If you take any prescription medications — especially blood pressure drugs, blood thinners, or sleep aids — check with your doctor or pharmacist before starting this product, because the interactions are real and affect over a thousand medications.

Pregnant or breastfeeding? Feverfew and California poppy aren't recommended; talk it over with your provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about KeepOnMovin' Peppermint, straight from the product label.

Brand Oregon's Wild Harvest
Barcode (UPC) 706195173511
Net contents 2 fl. Oz.; 59 mL
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 175643
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for KeepOnMovin' Peppermint by Oregon's Wild Harvest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.5 mL
Maximum serving Sizes:
2.5 mL
Servings per container
24
UPC/BARCODE
706195173511
IngredientAmount% DV
Biodynamic & Organic Proprietary Blend1190 mg--
Peppermint0 NP--
fresh White Willow0 NP--
fresh FeverFew0 NP--
fresh California Poppy0 NP--

Other ingredients: Biodynamic and organic Alcohol, organic Glycerin, organic Pear juice concentrate, organic Peppermint flavor extract, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The tastiest and most dynamic inflammation support formula we make.

Since 1994

Relief of mild pain related to exercise

24 tasty servings

Alcohol Content: Not more than 35%

Suggested/Recommended/Usage/Directions

Suggested Use: As an herbal tonic, take 2.5 mL (approx. three half-droppers) daily or as directed by your healthcare professional. Do not exceed recommended dose.

Shake well.

Precautions

Do not exceed recommended dose.

Caution: Keep out of reach of children.

Do not take if pregnant or nursing. If taking medication consult a healthcare professional before use.

Discontinue use if unusual symptoms occur.

Formulation

Does not contain dairy, wheat, gluten, peanuts, soy or corn allergens.

Certified Organic by Oregon Tilth

Non GMO

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

R6

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic Certified Organic

Demeter Certified Biodynamic

OTCO

GF

Non GMO

Storage

Store upright in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

KeepOnMovin' Peppermint by Oregon's Wild Harvest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

KeepOnMovin' Peppermint label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in KeepOnMovin' Peppermint by Oregon's Wild Harvest

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2.5 mL Dosage formLiquid Servings per container24 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Biodynamic & Organic Proprietary Blend

1190 mg per serving

Other (inactive) ingredients: Biodynamic and organic Alcohol, Organic Glycerin, Organic Pear juice concentrate, Organic Peppermint flavor extract, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

KeepOnMovin' Peppermint by Oregon's Wild Harvest Drug Interactions

Want to check YOUR meds against KeepOnMovin' Peppermint?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,029Drugs
1,029 Moderate

Ingredients driving the most interactions

fresh FeverFew 929
Peppermint 796
fresh California Poppy 248

Individual Drug Interactions

The ingredients in KeepOnMovin' Peppermint interact with 1,029 drugs. Click any drug to see the details.

3 of the 4 ingredients in KeepOnMovin' Peppermint interact with drugs. Each result below shows which ingredient is responsible. fresh FeverFew Peppermint fresh California Poppy

Each ingredient & the kinds of drugs it affects

For each ingredient in KeepOnMovin' Peppermint with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

fresh FeverFew7 drug types · 929 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, feverfew might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Laboratory research suggests that feverfew may inhibit platelet aggregation. Additionally, in one case report, a 36-year-old patient taking feverfew 2400 mg daily for 3 months experienced vaginal bleeding and a prolonged menstrual cycle, with a modest increase in partial thromboplastin time (PTT) and prothrombin time (PT).

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, feverfew might increase levels of drugs metabolized by CYP1A2.
Laboratory research shows that feverfew might inhibit CYP1A2. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, feverfew might increase levels of drugs metabolized by CYP2C19.
Laboratory research shows that feverfew might inhibit CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C8 (Cyp2C8) Substrates

Theoretically, feverfew might increase levels of drugs metabolized by CYP2C8.
Laboratory research shows that feverfew might inhibit CYP2C8. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, feverfew might increase levels of drugs metabolized by CYP2C9.
Laboratory research shows that feverfew might inhibit CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, feverfew might increase levels of drugs metabolized by CYP2D6.
Laboratory research shows that feverfew might inhibit CYP2D6. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, feverfew might increase levels of drugs metabolized by CYP3A4.
Laboratory research shows that feverfew might inhibit CYP3A4. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
fresh FeverFew full monograph & interactions

Peppermint5 drug types · 796 drugs

Cyclosporine (Neoral, Sandimmune)

Theoretically, peppermint oil might increase the levels and adverse effects of cyclosporine.
In animal research, peppermint oil inhibits cyclosporine metabolism and increases cyclosporine levels. Inhibition of cytochrome P450 3A4 (CYP3A4) may be partially responsible for this interaction. An interaction between peppermint oil and cyclosporine has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, peppermint might increase the levels of CYP2C19 substrates.
In vitro research shows that peppermint oil inhibits CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, peppermint might increase the levels of CYP2C9 substrates.
In vitro research shows that peppermint oil inhibits CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Clinical research in healthy volunteers shows that a single dose of peppermint oil 600 mg inhibits CYP3A4 enzymes and increases the AUC of felodipine, a CYP3A4 substrate. However, in vitro research suggests that peppermint oil only inhibits CYP3A4 at very high concentrations.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, peppermint might increase the levels of CYP1A2 substrates.
In vitro and animal research shows that peppermint oil and peppermint leaf inhibit CYP1A2. However, in clinical research, peppermint tea did not significantly affect the metabolism of caffeine, a CYP1A2 substrate. It is possible that the 6-day duration of treatment may have been too short to identify a difference.

Likelihood Possible Evidence B
Peppermint full monograph & interactions

fresh California Poppy1 drug type · 248 drugs

Cns Depressants

Theoretically, taking California poppy with drugs with sedative effects may increase the risk of sedative effects.
Laboratory research shows that California poppy has sedative effects.

Likelihood Possible Evidence D
fresh California Poppy full monograph & interactions
The maker

Brand information

Manufacturer and brand details for KeepOnMovin' Peppermint, from the product label.

Oregon's Wild Harvest

See all Oregon's Wild Harvest products
Name
Oregon's Wild Harvest
Street Address
1601 NE Hemlock Ave.
City
Redmond
State
OR
ZipCode
97756
Phone Number
1-800-316-6869
Web Address
oregonswildharvest.com
Pharmacist Counseling Corner

KeepOnMovin' Peppermint by Oregon's Wild Harvest: Common Questions

Does KeepOnMovin' Peppermint by Oregon's Wild Harvest interact with any medications?
Yes. Based on its ingredients, KeepOnMovin' Peppermint has a known interaction with 1,029 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
KeepOnMovin' Peppermint contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is peppermint safe to take if I'm pregnant or breastfeeding?
Peppermint tea and culinary amounts are likely safe in pregnancy and while nursing. However, this product is a concentrated liquid supplement, and the facts advise checking with your provider before using concentrated peppermint oil or supplements during pregnancy or lactation. Feverfew in the blend should be avoided in pregnancy because it may stimulate the uterus, and there isn't enough safety data for it while breastfeeding.
What are the most common side effects?
From peppermint, the most common are abdominal pain, belching, heartburn, diarrhea, and dry mouth. Feverfew can cause bloating, constipation, diarrhea, and nausea. Chewing fresh feverfew leaves — as opposed to commercial preparations — is more likely to cause mouth sores. California poppy has limited adverse-effect data, though nausea has been reported when combined with other ingredients.
Does this product actually work for IBS or digestive issues?
Peppermint is likely effective for IBS, so that's the ingredient with the strongest backing. Peppermint is also possibly effective for indigestion and nausea from chemotherapy or medical procedures. The feverfew and California poppy in the blend don't have established evidence for digestive support.
Can I take this if I'm on a blood thinner like warfarin?
Feverfew in this product may increase bleeding risk when combined with blood thinners or antiplatelet drugs — one case report documented unusual bleeding in someone taking high-dose feverfew. Talk to your doctor or pharmacist before adding this supplement if you're on warfarin, aspirin, or any blood thinner.
Why does the ingredient list include white willow if you couldn't check it?
White willow is one of the four active ingredients in the blend, but we don't hold interaction data for it in our database. That means we can't tell you whether it interacts with medications — it's not that we checked and found nothing. Mention it to your pharmacist when you ask about this product.
What happens if I stop taking feverfew after using it for a long time?
Stopping feverfew after long-term use may cause "post-feverfew syndrome" — symptoms like anxiety, headaches, and insomnia. If you've been taking this product regularly and want to stop, talk to your doctor or pharmacist about how to do it safely.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if KeepOnMovin' Peppermint is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

KeepOnMovin' Peppermint label
Go deeper

The Full Monographs Behind KeepOnMovin' Peppermint’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Peppermint

Interacts with 796 drugs

Peppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated for most adults, but it can cause heartbu...

Read the full Peppermint monograph → Herb & supplement monograph

Feverfew

Interacts with 929 drugs

Feverfew is a daisy-family herb best known for migraine prevention, where some studies suggest it may modestly lower how often migraines occur, though the evidence is mixed. It is generally...

Read the full Feverfew monograph → Herb & supplement monograph

California Poppy

Interacts with 248 drugs

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is very limited, so its true benefits are...

Read the full California Poppy monograph →
Sources

Sources & How We Checked

KeepOnMovin' Peppermint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 62 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Peppermint 41 references
  1. Liu JH, Chen GH, Yeh HZ, et al. Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial. J Gastroenterol 1997;32:765-8. PubMed
  2. Pittler MH, Ernst E. Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis. Am J Gastroenterol 1998;93:1131-5. PubMed
  3. Kline RM, Kline JJ, Di Palma J, Barbero GJ. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr 2001;138:125-8. PubMed
  4. Madisch A, Heydenreich CJ, Wieland V, et al. Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. A multicenter, reference-controlled, double-blind equivalence study. Arzneimittel
  5. May B, Kuntz HD, Kieser M, Kohler S. Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung 1996;46:1149-53.
  6. Micklefield GH, Greving I, May B. Effects of peppermint oil and caraway oil on gastroduodenal motility. Phytother Res 2000;14:20-3. DOI
  7. Morton CA, Garioch J, Todd P, et al. Contact sensitivity to menthol and peppermint in patients with intra-oral symptoms. Contact Dermatitis 1995;32:281-4. PubMed
  8. May B, Kohler S, Schneider B. Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia. Aliment Pharmacol Ther 2000;14:1671-7. PubMed
  9. Nash P, Gould SR, Bernardo DE. Peppermint oil does not relieve the pain of irritable bowel syndrome. Br J Clin Pract 1986;40:292-3. DOI
  10. Rees WD, Evans BK, Rhodes J. Treating irritable bowel syndrome with peppermint oil. Br Med J 1979;2:835-6. PubMed
  11. Davies SJ, Harding LM, Baranowski AP. A novel treatment of postherpetic neuralgia using peppermint oil. Clin J Pain 2002;18:200-2. PubMed
  12. Weston CF. Anal burning and peppermint oil. Postgrad Med J 1987;63:717. PubMed
  13. Dresser GK, Wacher V, Wong S, et al. Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo. Clin Pharmacol Ther 2002;72:247-55. PubMed
  14. Wacher VJ, Wong S, Wong HT. Peppermint oil enhances cyclosporine oral bioavailability in rats: comparison with D-alpha-tocopheryl poly(ethylene glycol 1000) succinate (TPGS) and ketoconazole. J Pharm Sci 2002;91:77-90.
  15. Lawson MJ, Knight RE, Tran K, et al. Failure of enteric-coated peppermint oil in the irritable bowel syndrome: a randomized double-blind crossover study. J Gastroenterol Hepatol 1988;3:235-8. DOI
  16. Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
  17. Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
  18. Rogers SN, Pahor AL. A form of stomatitis induced by excessive peppermint consumption. Dent Update 1995;22:36-7.
  19. Cappello G, Spezzaferro M, Grossi L, et al. Peppermint oil (Mintoil) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial. Dig Liver Dis 2007;39:530-6. PubMed
  20. Moghadam BK, Gier R, and Thurlow T. Extensive oral mucosal ulcerations caused by misuse of a commercial mouthwash. Cutis 1999;64:131-134.
  21. Andersen, K. E. Contact allergy to toothpaste flavors. Contact Dermatitis 1978;4(4):195-198. PubMed
  22. Barnard, D. R. Repellency of essential oils to mosquitoes (Diptera: Culicidae). J Med Entomol. 1999;36(5):625-629. PubMed
  23. Tamir, S., Davidovich, Z., Attal, P., and Eliashar, R. Peppermint oil chemical burn. Otolaryngol.Head Neck Surg. 2005;133(5):801-802. PubMed
  24. Kalavala, M., Hughes, T. M., Goodwin, R. G., Anstey, A. V., and Stone, N. M. Allergic contact dermatitis to peppermint foot spray. Contact Dermatitis 2007;57(1):57-58. PubMed
  25. Vermaat, H., van Meurs, T., Rustemeyer, T., Bruynzeel, D. P., and Kirtschig, G. Vulval allergic contact dermatitis due to peppermint oil in herbal tea. Contact Dermatitis 2008;58(6):364-365. PubMed
  26. Merat, S., Khalili, S., Mostajabi, P., Ghorbani, A., Ansari, R., and Malekzadeh, R. The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome. Dig.Dis.Sci. 2010;55(5):1385-1390. PubMed
  27. Tran, A., Pratt, M., and DeKoven, J. Acute allergic contact dermatitis of the lips from peppermint oil in a lip balm. Dermatitis 2010;21(2):111-115. DOI
  28. Hitz, Lindenmuller, I and Lambrecht, J. T. Oral care. Curr Probl.Dermatol 2011;40:107-115.
  29. Shavakhi, A., Ardestani, S. K., Taki, M., Goli, M., and Keshteli, A. H. Premedication with peppermint oil capsules in colonoscopy: a double blind placebo-controlled randomized trial study. Acta Gastroenterol Belg 2012;75(3):349-353.
  30. Lech, Y., Olesen, K. M., Hey, H., Rask-Pedersen, E., Vilien, M., and Ostergaard, O. [Treatment of irritable bowel syndrome with peppermint oil. A double- blind study with a placebo]. Ugeskr.Laeger 10-3-1988;150(40):2388-2389.
  31. Parys, B. T. Chemical burns resulting from contact with peppermint oil mar: a case report. Burns Incl.Therm.Inj. 1983;9(5):374-375. PubMed
  32. Bayat R, Borici-Mazi R. A case of anaphylaxis to peppermint. Allergy Asthma Clin Immunol. 2014;10(1):6. PubMed
  33. Rich G, Shah A, Koloski N, et al. A randomized placebo-controlled trial on the effects of Menthacarin, a proprietary peppermint- and caraway-oil-preparation, on symptoms and quality of life in patients with functional dyspepsia. Neurogastroenterol Motil 2 PubMed
  34. Douros A, Bronder E, Andersohn F, et al. Herb-Induced Liver Injury in the Berlin Case-Control Surveillance Study. Int J Mol Sci 2016;17(1). PubMed
  35. Begas E, Tsioutsiouliti A, Kouvaras E, et al. Effects of peppermint tea consumption on the activities of CYP1A2, CYP2A6, Xanthine Oxidase, N-acetyltranferase-2 and UDP-glucuronosyltransferases-1A1/1A6 in healthy volunteers. Food Chem Toxicol 2017;100:80-9 PubMed
  36. Cash BD, Epstein MS, Shah SM. A Novel Delivery System of Peppermint Oil Is an Effective Therapy for Irritable Bowel Syndrome Symptoms. Dig Dis Sci 2016;61(2):560-71. PubMed
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See these in context on the Peppermint monograph →

Feverfew 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Awang DVC. Prescribing therapeutic feverfew (Tancetum pathrnium (L.) Schultz Bip., syn. Chrysanthemumparthenium (L.) Bernh). Int Med 1998;1:11-3.
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See these in context on the Feverfew monograph →

California Poppy 3 references
  1. Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate
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See these in context on the California Poppy monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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