Major interaction on record — check this product against your medications before combining. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Kids Organic Elderberry Whole-Food Gummies Ingredients & Drug Interactions

by New Chapter

Kids Organic Elderberry Whole-Food Gummies label
See full label image
Gummy Or Jelly Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kids Organic Elderberry Whole-Food Gummies against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Kids Organic Elderberry Whole-Food Gummies is a dietary supplement by New Chapter with 3 active ingredients. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 421 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Apple, Elderberry Fruit Juice Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Kids Organic Elderberry Whole-Food Gummies by New Chapter

Ask about any prescription or over-the-counter medication and we check it for interactions with Kids Organic Elderberry Whole-Food Gummies by New Chapter — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Kids Organic Elderberry Whole-Food Gummies by New Chapter

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Fruit Blend” is a proprietary blend — the label gives one combined amount (2,350 mg) without saying how much of each component you get.

This gummy contains 3 active ingredients. Elderberry Fruit Juice Concentrate and organic ElderCraft European Elderberry extract are both forms of elderberry, a berry used in supplements for immune and respiratory support.

Apple is included for its antioxidant content and sweetness. The product also contains inactive ingredients — pectin (a natural thickener), rice flour, and lemon juice concentrate — which help form and flavor the gummy.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Immune support.
  • We looked for evidence on: Respiratory tract infections, Upper respiratory tract infection (URTI), Lower respiratory tract infections, Rhinosinusitis, Colds, Flu — and 1 related terms.
  • The closest evidence on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Rhinosinusitis, Lower respiratory tract infections.

For the claims commonly made about elderberry — hay fever relief, heart health, chronic fatigue, COPD, brain function, and fighting respiratory infections — the evidence we hold does not establish effectiveness. The data shows insufficient evidence for all these uses.

Similarly, the product's apple ingredient has insufficient evidence for the conditions it's sometimes promoted for, including Alzheimer's disease, cancer prevention, dental plaque, diabetes, and diarrhea.

The evidence, ingredient by ingredient Elderberry Apple

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly cooked elderberry (which this product should be, since it's a commercial gummy) is generally well tolerated in children. However, the data advises against elderberry supplements during pregnancy or breastfeeding because there isn't enough safety information.

Apple as a food is safe for most people in normal amounts — bloating and flatulence are the most common minor side effects. Apple seeds contain cyanide and should never be eaten in quantity, though whole apples and juice are safe.

Rarely, people allergic to related fruits (apricot, almond, plum, peach, pear, strawberry) may also react to apple, and severe allergic reactions are possible.

Side effects, ingredient by ingredient Elderberry Apple

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Apple, Elderberry.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 421 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your child's medications before using this product if they take heart and blood pressure drugs (especially atenolol, aliskiren), allergy medications (especially fexofenadine), diabetes drugs, lithium, or immunosuppressants. Apple juice significantly reduces blood levels of these medications.

Also check if your child is on any immunosuppressant — elderberry may interfere with how well it works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

If your child takes a heart or blood pressure medication, an allergy medication, a diabetes drug, lithium, or an immunosuppressant (especially after a transplant), check this product with your pharmacist before starting — the apple and elderberry in it may interfere with how those medications work. For children on no regular medications, the gummy is generally well tolerated, though it's not proven to prevent colds or boost immunity based on the data we hold.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kids Organic Elderberry Whole-Food Gummies, straight from the product label.

Brand New Chapter
Barcode (UPC) 727783903099
Net contents 30 100% Vegan Gummy(ies)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 304876
Product type Botanical
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kids Organic Elderberry Whole-Food Gummies by New Chapter, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gummy(ies)
Maximum serving Sizes:
1 Gummy(ies)
Servings per container
30
UPC/BARCODE
727783903099
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates2 Gram(s)1%, 1%
Added Sugars1 Gram(s)4%, 2%
Total Sugars1 Gram(s)--
Fruit Blend2350 mg--
Elderberry Fruit Juice Concentrate0 NP--
organic ElderCraft European Elderberry extract75 mg--
Apple0 NP--

Other ingredients: Pectin, Rice Flour, Lemon Juice Concentrate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

New Chapter Est, 1982

Copyright 2022 New Chapter, Inc.

Formulation

64x concentrated extract

Nutrition crafted for: Immune support

The magic inside: Great-tasting elderberry gummies for kids 2+ made with real fruit & no cane sugar

USDA Organic

Non GMO Project Verified nongmoproject.org

NSF Certified Gluten-Free

Certified Vegan Vegan.org

Certified Organic by Where Food Comes From Organic, Castle Rock, CO, USA

Made in Germany

Certified B Corporation This company meets the highest standards of social and environmental impact

Certified gluten-free by NSF; Certified vegan; no artificial flavors or colors.

Certified gluten-free by NSF; Certified vegan; no artificial flavors or colors.

Formula

The magic inside: Great-tasting elderberry gummies for kids 2+ made with real fruit & no cane sugar

OU (Kosher)

Great-tasting immune booster Supports children's healthy immune systems every day with clinically studied Black Elderberry (Sambucus nigra). Our potent, superior-quality fruit is sustainably grown in Austria, then highly concentrated in a solvent-free process. Inspiration by tradition, grounded in science. Superfood powered Powerful antioxidant action from super-dark elderberry flavonoids for immune support.

Immune support for kids Specially formulated for kids, activates immune defenses with the force of pure black elderberry.

Real elderberries! Made with pure elderberry extract, concentrated 64x for optimal benefit.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

USDA Organic

Non GMO Project Verified nongmoproject.org

NSF Certified Gluten-Free

Certified Vegan Vegan.org

OU (Kosher)

Certified B Corporation This company meets the highest standards of social and environmental impact

General Statements

For questions or comments call 888-874-4461

Please recycle this BPA-free bottle.

The New Chapter Money-Back Guarantee We proudly stand behind every product we make. However, if you are not satisfied, please visit www.newchapter.com/guarantee for refund details.

Join us at newchapter.com!

Precautions

Caution: As with any dietary supplement, advise your healthcare professional of the use of this product if your children have a medical condition or are taking medication. Discontinue use and contact your healthcare professional if your children experience a side effect or an allergic reaction. Keep out of reach of children.

Do not exceed suggested use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested use: Ages 2 years and above, chew one gummy daily. Ensure child chews thoroughly.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kids Organic Elderberry Whole-Food Gummies by New Chapter label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kids Organic Elderberry Whole-Food Gummies label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kids Organic Elderberry Whole-Food Gummies by New Chapter

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fruit Blend

2350 mg per serving

Organic ElderCraft European Elderberry extract

75 mg per serving

Other (inactive) ingredients: Pectin, Rice Flour, Lemon Juice Concentrate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kids Organic Elderberry Whole-Food Gummies by New Chapter Drug Interactions

Want to check YOUR meds against Kids Organic Elderberry Whole-Food Gummies?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
421Drugs
47 Major 374 Moderate

Ingredients driving the most interactions

Apple 300
Elderberry Fruit Juice Concentrate 121

Individual Drug Interactions

The ingredients in Kids Organic Elderberry Whole-Food Gummies interact with 421 drugs. Click any drug to see the details.

2 of the 3 ingredients in Kids Organic Elderberry Whole-Food Gummies interact with drugs. Each result below shows which ingredient is responsible. Apple Elderberry Fruit Juice Concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Kids Organic Elderberry Whole-Food Gummies with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Apple7 drug types · 300 drugs

Organic Anion-Transporting Polypeptide Substrates (Oatp)

Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Research shows that consuming apple juice inhibits OATP, which reduces bioavailability of oral drugs that are substrates of OATP. Fexofenadine, atenolol, and aliskiren are substrates of OATP. Clinical research shows that coadministration of apple juice decreases bioavailability of fexofenadine by up to 78%, aliskiren by 63%, and atenolol by up to 82%. These effects appear to increase with larger quantities of apple juice. It is thought that apple juice might affect OATP for only a short time. Therefore, separating drug administration and consumption of apple juice by at least 4 hours might avoid this interaction.

Likelihood Likely Evidence B
Aliskiren (Tekturna, Rasilez)

Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of aliskiren.
Pharmacokinetic research shows that coadministration of apple juice 200 mL along with aliskiren 150 mg decreases the bioavailability of aliskiren by 63%. Apple juice seems to inhibit organic anion transporting polypeptide (OATP), which is involved in drug uptake in the gut, liver, and kidney. It is thought that apple juice might affect OATP for only a short time. Therefore, separating drug administration and consumption of apple juice by at least 4 hours might avoid this interaction.

Likelihood Probable Evidence B
Antidiabetes Drugs

Theoretically, consuming apple juice with antidiabetes drugs might interfere with blood glucose control.
Clinical research suggests that consuming apples or drinking apple juice can raise blood glucose levels, with the effects of drinking apple juice being more significant than consuming apples.

Likelihood Possible Evidence D
Antihypertensive Drugs

Consuming apple juice with antihypertensive drugs might interfere with blood pressure control.
Some clinical evidence suggests that consuming apple and cherry juice can increase blood pressure in elderly patients.

Likelihood Probable Evidence B
Atenolol (Tenormin)

Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of atenolol.
Pharmacokinetic research shows that coadministration of apple juice 600-1200 mL decreases levels of atenolol by 58% to 82% in a dose-dependent manner. Apple juice seems to inhibit organic anion transporting polypeptide (OATP), which is involved in drug uptake in the gut, liver, and kidney. It is thought that apple juice might affect OATP for only a short time. Therefore, separating drug administration and consumption of apple juice by at least 4 hours might avoid this interaction.

Likelihood Probable Evidence B
Fexofenadine (Allegra)

Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of fexofenadine.
Pharmacokinetic research shows that coadministration of apple juice 400-1200 mL along with fexofenadine 60-120 mg decreases bioavailability of fexofenadine by up to 78%. Coadministration with smaller quantities of apple juice (150 mL or less) does not appear to affect the bioavailability of fexofenadine. Apple juice seems to inhibit organic anion transporting polypeptide (OATP), which is involved in drug uptake in the gut, liver, and kidney. It is thought that apple juice might affect OATP for only a short time. Therefore, separating drug administration and consumption of apple juice by at least 4 hours might avoid this interaction.

Likelihood Likely Evidence B
Lithium

There is some concern that concomitant consumption of apple juice might decrease oral absorption and blood levels of lithium.
In one case report, a patient had an undetectable serum lithium level when lithium citrate was administered with apple juice. When lithium was administered with an alternative beverage, the lithium level became detectable and the patient demonstrated clinical improvement.

Likelihood Possible Evidence D
Apple full monograph & interactions

Elderberry Fruit Juice Concentrate2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
Elderberry Fruit Juice Concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kids Organic Elderberry Whole-Food Gummies, from the product label.

New Chapter

See all New Chapter products
Name
NEW CHAPTER, INC.
Street Address
90 TECHNOLOGY DRIVE
City
BRATTLEBORO
State
VT
ZipCode
05301
Web Address
www.newchapter.com
Pharmacist Counseling Corner

Kids Organic Elderberry Whole-Food Gummies by New Chapter: Common Questions

Does Kids Organic Elderberry Whole-Food Gummies by New Chapter interact with any medications?
Yes. Based on its ingredients, Kids Organic Elderberry Whole-Food Gummies has a known interaction with 421 medications, including 47 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kids Organic Elderberry Whole-Food Gummies contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I give this to my child if they're taking medication?
Only with your pharmacist's approval. The apple and elderberry in this gummy can interfere with several common children's medicines — heart drugs, allergy meds, diabetes drugs, and immune-suppressing drugs especially. Your pharmacist can tell you if your child's specific medication is affected.
Is this gummy safe for babies and young toddlers?
The product facts we hold don't specify a safe age range. Talk with your pediatrician or pharmacist about whether it's right for your child's age.
Will this help my child avoid getting sick?
The evidence we have doesn't establish that elderberry prevents or shortens respiratory infections in children. The data shows insufficient evidence for that use.
What if my child swallows apple seeds from this gummy?
Whole gummies won't expose your child to raw seeds in dangerous amounts — the product is a processed food. Apple seeds do contain cyanide, but serious harm only happens with intentional consumption of large quantities of seeds, which isn't a risk here.
Are there any fillers or unwanted ingredients I should know about?
Besides the active ingredients, this gummy contains pectin (a natural thickener), rice flour, and lemon juice concentrate as inactive ingredients — these are typical gummy binders and flavorings.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Kids Organic Elderberry Whole-Food Gummies is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kids Organic Elderberry Whole-Food Gummies label
Go deeper

The Full Monographs Behind Kids Organic Elderberry Whole-Food Gummies’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Elderberry

Interacts with 121 drugs

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...

Read the full Elderberry monograph → Herb & supplement monograph

Apple

Interacts with 300 drugs

Apples are a nutritious whole food that provides fiber, vitamins, and antioxidant plant compounds, and eating them regularly fits well into a healthy diet. While research suggests apples may...

Read the full Apple monograph →
Sources

Sources & How We Checked

Kids Organic Elderberry Whole-Food Gummies's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Apple 16 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Bailey DG, Dresser GK, Munoz C, et al. Reduction of fexofenadine bioavailability by fruit juices. Clin Pharmacol Ther 2001;69:P21.
  3. Rodriguez J, Crespo JF, Lopez-Rubio A, et al. Clinical cross-reactivity among foods of the Rosaceae family. J Allergy Clin Immunol 2000;106:183-189. PubMed
  4. Greenblatt DJ. Analysis of drug interactions involving fruit beverages and organic anion-transporting polypeptides. J Clin Pharmacol 2009;49:1403-7. PubMed
  5. Bailey DG. Fruit juice inhibition of uptake transport: a new type of food-drug interaction. Br J Clin Pharmacol 2010;70:645-55. PubMed
  6. Kamath AV, Yao M, Zhang Y, Chong S. Effect of fruit juices on the oral bioavailability of fexofenadine in rats. J Pharm Sci 2005;94:233-9. PubMed
  7. Tapaninen T, Neuvonen PJ, Niemi M. Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren. Br J Clin Pharmacol 2011;71:718-26. PubMed
  8. Jeon H, Jang IJ, Lee S, et al. Apple juice greatly reduces systemic exposure to atenolol. Br J Clin Pharmacol 2012 May 11. doi: 10.1111/j.1365-2125.2012.04324.x. [Epub ahead of print]. PubMed
  9. Visvanathan, R., Chen, R., Horowitz, M., and Chapman, I. Blood pressure responses in healthy older people to 50 g carbohydrate drinks with differing glycaemic effects. Br J Nutr 2004;92(2):335-340. PubMed
  10. Asp, N. G., Agardh, C. D., Ahren, B., Dencker, I., Johansson, C. G., Lundquist, I., Nyman, M., Sartor, G., and Schersten, B. Dietary fibre in type II diabetes. Acta Med Scand Suppl 1981;656:47-50. PubMed
  11. Akamine Y, Miura M, Komori H, et al. Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers. Eur J Clin Pharmacol. 2014 Sep;70(9):1087-95. PubMed
  12. Luo J, Imai H, Ohyama T, et al. The Pharmacokinetic Exposure to Fexofenadine is Volume-Dependently Reduced in Healthy Subjects Following Oral Administration With Apple Juice. Clin Transl Sci. 2016 Aug;9(4):201-6. PubMed
  13. Tsiougkos N, Vovolis V. Repeated anaphylactic episodes to orange and apple. Eur Ann Allergy Clin Immunol. 2013 May;45(3):113-5.
  14. Rubido S, García-Caballero L, Abeleira MT, Limeres J, García M, Diz P. Effect of chewing an apple on dental plaque removal and on salivary bacterial viability. PLoS One. 2018;13(7):e0199812. PubMed
  15. Krishnasamy S, Lomer MCE, Marciani L, et al. Processing apples to puree or juice speeds gastric emptying and reduces postprandial intestinal volumes and satiety in healthy adults. J Nutr 2020;150(11):2890-9. PubMed
  16. Awan S, Abelleira A, Khehra L, Hieber R. Undetectable serum lithium concentrations after coadministration of liquid lithium citrate and apple juice: A case report. Ment Health Clin. 2021;11(1):27-30. PubMed

See these in context on the Apple monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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