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Dietary supplement

L-Theanine 200 mg Ingredients & Drug Interactions

by DaVinci Laboratories

L-Theanine 200 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking L-Theanine 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

L-Theanine 200 mg is a dietary supplement by DaVinci Laboratories with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, relaxation and calm, sleep support.Based on those ingredients, 565 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Suntheanine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against L-Theanine 200 mg by DaVinci Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with L-Theanine 200 mg by DaVinci Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of L-Theanine 200 mg by DaVinci Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-theanine (sold here as Suntheanine), 200 mg per capsule. Theanine is an amino acid found naturally in tea that works in the brain to promote relaxation without heavy sedation.

The capsule also contains microcrystalline cellulose, cellulose, and leucine as inactive ingredients (binders and fillers).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Theanine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support relaxation and reduce irritability and low mood.
  • We looked for evidence on: Generalized anxiety disorder (GAD), Stress, Depression, Insomnia, Anxiety, Mood disturbance — and 2 related terms.
  • The closest evidence on file: Theanine is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD) (Natural Medicines).
  • Also on file: Theanine is rated "Insufficient Reliable Evidence To Rate" for Depression, Insomnia, Stress.

The evidence we hold shows theanine is possibly effective for cognitive function — meaning there's some promising research behind it. For age-related cognitive decline, Alzheimer disease, generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), and cancer, the evidence isn't yet established well enough to rate it.

If you're considering this supplement for one of those conditions, talk with your doctor about what the current research says and whether it's a fit for you.

The evidence, ingredient by ingredient Theanine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Theanine is generally well tolerated in healthy adults for short-term use, but its safety over the long term hasn't been studied closely enough to know. The most common side effects reported are headaches, drowsiness, increased sleep duration, and vivid dreams.

One pediatric case of facial tics was reported, but it stopped when the product was discontinued and wasn't confirmed to be caused by theanine. There isn't enough safety data on theanine in pregnancy or while breastfeeding, so the safety data advises against use during either period.

If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Theanine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Theanine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 565 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your doctor or pharmacist if you take blood pressure medication — theanine can enhance their effects and lower your pressure further. Also double-check if you're on sedating drugs like sleep aids or anti-anxiety medications, since theanine may add to drowsiness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

L-Theanine may help with focus and calm if you're looking for a gentler option, but it's most important to check it against your blood pressure medication if you're on one — theanine could make those drugs work too well. It's also worth a conversation with your doctor or pharmacist if you take sedating medications or if you're pregnant or breastfeeding, since the data there is limited.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Theanine 200 mg, straight from the product label.

Brand DaVinci Laboratories
Barcode (UPC) 026664213235
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 303974
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Theanine 200 mg by DaVinci Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
026664213235
IngredientAmount% DV
Suntheanine200 mg--

Other ingredients: Microcrystalline Cellulose, Cellulose, Leucine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Truth We pledge total truth in labeling. Our family of products contains only the purest and most potent ingredients. Guaranteed.

Formulation

Color of this product may vary due to color variations of the natural ingredients.

A Dietary Supplement to support relaxation and reduce irritability and low mood states

Vegetarian

Gluten free

Precautions

Warning: If pregnant or nursing, consult your healthcare practitioner before taking this product.

Keep out of reach of children.

To obtain product information or report a serious adverse event, call 1-800-325-1776.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Suntheanine is a registered trademark of Taiyo International, Inc.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

A Dietary Supplement to support relaxation and reduce irritability and low mood states

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule daily, or as directed by your healthcare practitioner.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

L-Theanine 200 mg by DaVinci Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

L-Theanine 200 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in L-Theanine 200 mg by DaVinci Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Suntheanine

Interacts with
565 drugs
200 mg per serving Form: L-Theanine

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong dro...

Suntheanine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Cellulose, Leucine. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Theanine 200 mg by DaVinci Laboratories Drug Interactions

Want to check YOUR meds against L-Theanine 200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
565Drugs
172 Moderate 393 Minor

Ingredients driving the most interactions

Suntheanine 565

Individual Drug Interactions

The ingredients in L-Theanine 200 mg interact with 565 drugs. Click any drug to see the details.

1 of the 1 ingredient in L-Theanine 200 mg interact with drugs. Each result below shows which ingredient is responsible. Suntheanine

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Theanine 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Suntheanine3 drug types · 565 drugs

Antihypertensive Drugs

Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Animal research shows that theanine can lower blood pressure in spontaneously hypertensive animals. Theoretically, concomitant use of theanine and antihypertensive drugs might potentiate the antihypertensive activity.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Theoretically, theanine may compete with glutamate and/or increase plasma gamma-aminobutyric acid (GABA) levels, which could cause CNS depression. In one clinical study, some subjects taking oral theanine reported drowsiness.

Likelihood Unlikely Evidence D
Serotonergic Drugs

Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting. Some studies suggest it can increase serotonin levels in the brain while others report that it may decrease them. Nevertheless, there have been no reports of l-theanine being a causative agent in serotonergic-related side effects or serotonin syndrome.

Likelihood Unlikely Evidence C
Suntheanine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for L-Theanine 200 mg, from the product label.

DaVinci Laboratories

See all DaVinci Laboratories products
Name
DaVinci Laboratories a division of FoodScience LLC
Street Address
929 Harvest Lane
City
Williston
State
VT
ZipCode
05495
Phone Number
1-800-325-1776
Web Address
www.davincilabs.com
Pharmacist Counseling Corner

L-Theanine 200 mg by DaVinci Laboratories: Common Questions

Does L-Theanine 200 mg by DaVinci Laboratories interact with any medications?
Yes. Based on its ingredients, L-Theanine 200 mg has a known interaction with 565 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Theanine 200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data on L-theanine during pregnancy or breastfeeding, so it's best to avoid it during both. Talk with your doctor or pharmacist for personalized advice if you're in either situation.
What are the most common side effects?
Headaches and drowsiness are the main ones people report. Some also say they sleep longer or have more vivid dreams. These are generally mild, but if they bother you, stop taking it and check in with your pharmacist.
Does this actually work for anxiety or focus?
The evidence shows it's possibly effective for cognitive function — meaning there's some research backing it up. For anxiety disorders like GAD or OCD, the evidence isn't yet strong enough to say. Your own experience may vary, and it's worth talking to your doctor about whether it's right for your needs.
Is it safe to take long-term?
We have good safety data for short-term use in healthy adults, but long-term safety hasn't been studied enough to know for sure. If you're thinking about taking it regularly for months or longer, discuss that with your doctor.
What is Suntheanine?
Suntheanine is a branded form of L-theanine, the same amino acid found in tea. It's the active ingredient in this product and works in your brain to support relaxation and focus.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Theanine 200 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Theanine 200 mg label
Go deeper

The Full Monographs Behind L-Theanine 200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Theanine

Interacts with 565 drugs

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong drowsiness. Early research suggests it may...

Read the full Theanine monograph →
Sources

Sources & How We Checked

L-Theanine 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Theanine 6 references
  1. Yokogoshi H, Kobayashi M. Hypotensive effect of gamma-glutamylethylamide in spontaneously hypertensive rats. Life Sci 1998;62:1065-8.
  2. Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., and Scholey, A. B. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol.Psychol. 2008;77(2):113-122. PubMed
  3. Yokogoshi, H., Kato, Y., Sagesaka, Y. M., Takihara-Matsuura, T., Kakuda, T., and Takeuchi, N. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci.Biotechnol.Biochem. 1995;59(4):615-618. PubMed
  4. Lyon MR, Kapoor MP, Juneja LR. The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. Altern Med Rev. 2011;16(4):348-
  5. Hidese S, Ota M, Wakabayashi C, et al. Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study. Acta Neuropsychiatr 2017;29(2):72-9.
  6. Tsuchiya T, Honda H, Oikawa M, et al. Oral administration of the amino acids cystine and theanine attenuates the adverse events of S-1 adjuvant chemotherapy in gastrointestinal cancer patients. Int J Clin Oncol 2016;21(6):1085-90. PubMed

See these in context on the Theanine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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