No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Lactoferrin 100% Ingredients & Drug Interactions

by Symbiotics

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

Lactoferrin 100% is a dietary supplement by Symbiotics with 1 active ingredient. Its ingredients are commonly taken for iron deficiency and anemia support, immune support, gut health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lactoferrin 100% by Symbiotics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Lactoferrin 100% contains one active ingredient: bovine lactoferrin, a protein found naturally in milk and other body fluids. The capsule itself is made with gelatin as an inactive ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Lactoferrin's overall clinical evidence instead.

Moderate

Some clinical evidence supports Lactoferrin for:

Why this rating?
  • The label markets general wellness (“natural antioxidant support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Pregnancy-related iron deficiency — rated "Possibly Effective" (Natural Medicines).
  • On file: Sepsis — rated "Possibly Effective" (Natural Medicines).

The evidence for lactoferrin is mixed. It's rated possibly effective for sepsis and pregnancy-related iron deficiency.

However, it's rated likely ineffective for reducing fetal and premature infant mortality and for preventing necrotizing enterocolitis (a serious gut condition in premature infants). The data we have doesn't show it works reliably for those uses.

The evidence, ingredient by ingredient Lactoferrin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactoferrin is generally well tolerated at typical doses. The most common side effects are gastrointestinal — diarrhea, constipation, nausea, and stomach discomfort — though these are less frequent than with other iron supplements.

At higher doses of 7.2 grams daily, you're more likely to experience constipation, diarrhea, fatigue, chills, or loss of appetite. Long-term safety data are limited, so we don't have much information on how safe it is beyond the short term.

In pregnancy, safety isn't fully established, so use only under medical supervision. Lactoferrin occurs naturally in breast milk, but the safety of taking supplements while breastfeeding hasn't been well studied.

Talk with your doctor or pharmacist before using this product if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Lactoferrin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked. Before you start, run your specific medications through the checker on this page or confirm with your doctor or pharmacist that it's okay to combine with anything you're taking.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Lactoferrin 100% is generally well tolerated at standard doses and has no known medication interactions. If you're considering it for sepsis or pregnancy-related iron deficiency — the uses with the strongest evidence — talk it over with your doctor or pharmacist first, especially if you're pregnant or breastfeeding, since safety data in those situations are incomplete.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lactoferrin 100%, straight from the product label.

Brand Symbiotics
Barcode (UPC) 647303040069
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2015
DSLD ID 41304
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lactoferrin 100% by Symbiotics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
647303040069
IngredientAmount% DV
bovine Lactoferrin250 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

LACTOFERRIN SUPPLEMENT

General Statements

NATURAL ANTIOXIDANT*

Manufactured in the U.S.A.

ITEM NO. 04UGGLAC

EXPIRATION DATE ON BOTTOM OF CONTAINER

IMMUNE SUPPORT*

Lactoferrin helps coordinate the body's immune response through several mechanisms of action. Its iron-binding property robs fuel needed by cells that are not part of the body while delivering iron to body cells in need. It enhances oxygenation of tissues while supporting white blood cell activity. Lactoferrin also acts as an antioxidant to prevent free radical formation.

Lactoferrin promotes intestinal health by scavenging iron and balancing healthy flora in the GI tract. By modulating healthy levels of iron in the body, Lactoferrin plays a key role in maintaining overall health.

Symbiotics 100% Lactoferrin is freeze dried to preserve maximum bioactivity. Extra processing enhances its protein structure to increase effectiveness.

Quality and Purity Guaranteed - We guarantee that this product meets the highest standards of quality, purity and freshness.

Robs Fuel from Cells that are not part of the Body*

- Helps Enhance Tissue Oxygenation* - Provides Iron to Support White Blood Cells*

Suggested/Recommended/Usage/Directions

Directions: Take ONE capsule twice daily on an empty stomach with 8 oz. of water, or open capsule and sprinkle over small amount of food.

Formula

Suitable for lactose-free diets.

Contains Milk.

Precautions

Contains Milk.

Each bottle is safety sealed with an outer neckband and inner seal. Do not use if neckband is broken or missing.

Storage

Close tightly and store in a dry place at room temperature.

Brand IP Statement(s)

(C)2012

Symbiotics(R) is a registered trademarks of Prevention, LLC.

Nature's First Immune Defense(TM)*

General

4005-012B v01

Formulation

Our Lactoferrin comes from USDA Grade A dairies that are hormone, pesticide, antibiotic and rBST free.

Seals/Symbols

QUALITY GUARANTEE PURITY

Symbiotics(R)

Best Iron-binding Capacity FOR EFFECTIVE ACTION

FDA Disclaimer Statement

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

See for yourself

Lactoferrin 100% by Symbiotics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lactoferrin 100% by Symbiotics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Bovine Lactoferrin

No known
interactions
250 mg per serving Form: Milk

Lactoferrin is an iron-binding protein found naturally in milk and other body fluids, and supplements are usually made from cow's milk or rice. It is...

Bovine Lactoferrin monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lactoferrin 100% by Symbiotics Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lactoferrin 100%. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lactoferrin 100%, from the product label.

Symbiotics

See all Symbiotics products
Name
Naturade a division of Prevention, LLC
City
Orange
State
CA
ZipCode
92868
Phone Number
1-800-421-1830
Web Address
www.naturade.com
Pharmacist Counseling Corner

Lactoferrin 100% by Symbiotics: Common Questions

Does Lactoferrin 100% by Symbiotics interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lactoferrin 100%. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lactoferrin 100% contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is lactoferrin?
Lactoferrin is a protein found naturally in milk, tears, saliva, and other body fluids. The version in this supplement comes from cow's milk (bovine lactoferrin). It's thought to play a role in fighting infection and supporting immune function.
Will this help with iron deficiency?
Lactoferrin is rated possibly effective for iron deficiency specifically in pregnancy. For other types of iron deficiency, the evidence we have doesn't establish whether it works. If you have iron deficiency, talk with your doctor or pharmacist about whether this is the right choice for your situation.
What side effects should I watch for?
At typical doses, the most common side effects are gastrointestinal — diarrhea, constipation, nausea, or stomach discomfort — though these occur less often than with other iron supplements. If you take higher doses (7.2 grams daily), you're more likely to experience those effects plus fatigue, chills, or loss of appetite.
Is it safe to take while pregnant?
Safety in pregnancy isn't fully established, so use only under medical supervision. Talk with your doctor or pharmacist before starting if you're pregnant.
Can I take this while breastfeeding?
Lactoferrin occurs naturally in breast milk, but we don't have solid data on whether supplements are safe while breastfeeding. Talk with your doctor or pharmacist for personalized advice.
How much does the gelatin capsule matter if I'm vegetarian?
The capsule is made from gelatin, which is animal-derived. If you follow a vegetarian or vegan diet, this product won't work for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lactoferrin 100% is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lactoferrin 100% label
Go deeper

The Full Monographs Behind Lactoferrin 100%’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lactoferrin 100%'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactoferrin 6 references
  1. Food and Drug Administration, CFSAN/Office of Food Additive Safety. Agency Response Letter GRAS Notice No. GRN 000130. 2003. Available at: http://www.cfsan.fda.gov/~rdb/opa-g130.html (Accessed 29 June 2005).
  2. Okada S, Tanaka K, Sato T, et al. Dose-response trial of lactoferrin in patients with chronic hepatitis C. Jpn J Cancer Res 2002;93:1063-9. PubMed
  3. Abu Hashim H, Foda O, Ghayaty E. Lactoferrin or ferrous salts for iron deficiency anemia in pregnancy: A meta-analysis of randomized trials. Eur J Obstet Gynecol Reprod Biol. 2017;219:45-52. PubMed
  4. Tarnow-Mordi WO, Abdel-Latif ME, Martin A, et al. The effect of lactoferrin supplementation on death or major morbidity in very low birthweight infants (LIFT): a multicentre, double-blind, randomised controlled trial. Lancet Child Adolesc Health. 2020 Jun PubMed
  5. ELFIN trial investigators group. Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial. Lancet. 2019 Feb 2;393(10170):423-433. doi: 10.1016/S0140-6736(18)32221-9.
  6. Lepanto MS, Rosa L, Cutone A, Conte MP, Paesano R, Valenti P. Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: An interventional study. Front Immunol. 2018 Sep 21;9:2123. PubMed

See these in context on the Lactoferrin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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