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Dietary supplement

Lemon Balm Glycerite Ingredients & Drug Interactions

by Herbalist & Alchemist

Lemon Balm Glycerite label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lemon Balm Glycerite against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lemon Balm Glycerite is a dietary supplement by Herbalist & Alchemist with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 264 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are dried Lemon Balm herb extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lemon Balm Glycerite by Herbalist & Alchemist

Ask about any prescription or over-the-counter medication and we check it for interactions with Lemon Balm Glycerite by Herbalist & Alchemist — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lemon Balm Glycerite by Herbalist & Alchemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: dried lemon balm herb extract in a base of vegetable glycerin and distilled water. Lemon balm is a mint-family herb traditionally used for relaxation and stress relief.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: nervous system balance.
  • We looked for evidence on: Anxiety, Stress, Insomnia, Depression, Attention deficit-hyperactivity disorder (ADHD), restlessness — and 2 related terms.
  • The strongest evidence on file: Lemon Balm is rated "Possibly Effective" for Depression (Natural Medicines).
  • Also on file: Lemon Balm is rated "Possibly Effective" for Stress.
  • Also on file: Lemon Balm is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Attention deficit-hyperactivity disorder (ADHD), Insomnia.

The evidence on lemon balm supports possibly effective use for cold sores (herpes labialis), stress, and depression. That means there's some human trial data backing these uses, but the evidence isn't yet conclusive.

The strength of what we know is the same across all three.

The evidence, ingredient by ingredient Lemon Balm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lemon balm is generally well tolerated for short-term use in healthy adults, though high doses and long-term safety haven't been thoroughly studied. In trials, dizziness and sedation were reported but didn't occur more often than with placebo, and using it with alcohol didn't affect reaction time or thinking.

One rare case of heart rhythm changes and QT prolongation was reported in someone taking a multi-ingredient workout product containing lemon balm, but it's unclear whether lemon balm alone caused it; symptoms reversed within hours to weeks after stopping. During pregnancy, there isn't enough reliable safety data, so it's best avoided unless your doctor advises otherwise.

While breastfeeding, safety information is limited, so talk with your doctor before use.

Side effects, ingredient by ingredient Lemon Balm

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lemon Balm.
  • The most serious interaction on file is rated Moderate.
  • For scale: 264 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check it with your doctor or pharmacist if you're on CNS depressants—sedatives, sleep aids, some pain relievers, or other drugs that make you drowsy—or if you take thyroid hormone replacement therapy. Both are Moderate-severity interactions documented for lemon balm.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Lemon Balm Glycerite may help with cold sores, stress, and low mood based on possibly effective evidence, but it does interact with CNS depressants and thyroid medication. If you take sedating drugs or thyroid replacement, check with your doctor or pharmacist before starting.

For pregnancy or breastfeeding, the same conversation is important.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lemon Balm Glycerite, straight from the product label.

Brand Herbalist & Alchemist
Barcode (UPC) 667056118365
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Nov 21, 2019
DSLD ID 209243
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lemon Balm Glycerite by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 mL
Maximum serving Sizes:
6 mL
Servings per container
10
UPC/BARCODE
667056118365
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
dried Lemon Balm herb extract6 mL--

Other ingredients: Vegetable Glycerin, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Melissa officinalis

OK

General Statements

Promotes nervous system balance

Botanical preparation ratio 1:5

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 80-120 drops (4-6 mL) in juice or water. Take 4 times per day. Shake well before using.

Precautions

Keep out of children's reach

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

OK

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lemon Balm Glycerite by Herbalist & Alchemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lemon Balm Glycerite label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lemon Balm Glycerite by Herbalist & Alchemist

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 mL Dosage formLiquid Servings per container10 Amounts shown are per serving.

Dried Lemon Balm herb extract

Interacts with
264 drugs
6 mL per serving

Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold so...

Dried Lemon Balm herb extract monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lemon Balm Glycerite by Herbalist & Alchemist Drug Interactions

Want to check YOUR meds against Lemon Balm Glycerite?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
264Drugs
264 Moderate

Ingredients driving the most interactions

dried Lemon Balm herb extract 264

Individual Drug Interactions

The ingredients in Lemon Balm Glycerite interact with 264 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lemon Balm Glycerite interact with drugs. Each result below shows which ingredient is responsible. dried Lemon Balm herb extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Lemon Balm Glycerite with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

dried Lemon Balm herb extract2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Lemon balm seems to have CNS depressant activity in animals and in humans.

Likelihood Possible Evidence B
Thyroid Hormone

Theoretically, lemon balm might interfere with thyroid hormone replacement therapy.
In vitro, constituents of lemon balm extract bind to thyroid stimulating hormone (TSH), preventing TSH receptor-binding and leading to the inhibition of TSH-stimulated adenylate cyclase activity. In animals, lemon balm extract has been shown to decrease levels of circulating TSH and inhibit thyroid secretion.

Likelihood Possible Evidence D
dried Lemon Balm herb extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lemon Balm Glycerite, from the product label.

Herbalist & Alchemist

See all Herbalist & Alchemist products
Name
Herbalist & Alchemist, Inc.
City
Washington
State
NJ
ZipCode
07882
Phone Number
800-611-8235
Web Address
www.herbalist-alchemist.com
Pharmacist Counseling Corner

Lemon Balm Glycerite by Herbalist & Alchemist: Common Questions

Does Lemon Balm Glycerite by Herbalist & Alchemist interact with any medications?
Yes. Based on its ingredients, Lemon Balm Glycerite has a known interaction with 264 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lemon Balm Glycerite contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for cold sores?
Lemon balm is rated possibly effective for cold sores based on human trials. That means there's real evidence it may help, but more research is needed to be certain.
Will it make me drowsy?
Dizziness and sedation have been reported with lemon balm, but trials show these effects don't happen more often than with placebo. Individual responses vary, so pay attention to how you feel when you start.
Is it safe during pregnancy?
There isn't enough reliable safety data, so it's best avoided during pregnancy unless your doctor advises otherwise. That's a conversation to have with your own provider.
What's the glycerin for?
Vegetable glycerin is an inactive ingredient that serves as the liquid base for the extract—it helps preserve the herb and makes the product easy to dose and take.
Can I use it long-term?
Lemon balm is well tolerated for short-term use, but long-term safety hasn't been well studied. Talk with your doctor about how long you plan to use it.
Is it safe to combine with alcohol?
Research shows lemon balm used with alcohol doesn't affect reaction time or cognitive performance in trials. Still, if you're taking a CNS depressant or other medication, ask your pharmacist before mixing either with alcohol.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lemon Balm Glycerite is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lemon Balm Glycerite label
Go deeper

The Full Monographs Behind Lemon Balm Glycerite’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lemon Balm

Interacts with 264 drugs

Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold sores. Early studies are promising but gen...

Read the full Lemon Balm monograph →
Sources

Sources & How We Checked

Lemon Balm Glycerite's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lemon Balm 12 references
  1. Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine 1994;1:25-31.
  2. Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003;74:863-6. PubMed
  3. Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav 2002;72:953-64. PubMed
  4. Albrecht M, Berger W, Laux P, Schmidt U, et al. Psychopharmaka und Verkehrssicherheit. Der Einfluß von Euvegal® - Dragees forte auf die Fahrtüchtigkeit und Kombinationswirkungen mit Alkohol Z Allg Med 1995;71:1215-25.
  5. Herberg, KW. Nebenwirkungen pflanzlicher Beruhigungsmittel/ Leistung und Befinden nach Einnahme einer Baldrian-Hopfen-Kombination. Z.Allg Med 1996;72:234-240.
  6. Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991 Apr;57:105-9.
  7. Sourgens H, Winterhoff H, Gumbinger HG, et al. Antihormonal effects of plant extracts. TSH- and prolactin-suppressing properties of Lithospermum officinale and other plants. Planta Med. 1982 Jun;45:78-86. DOI
  8. Auf'mkolk M, Ingbar JC, Amir SM, et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology. 1984 Aug;115:527-34. PubMed
  9. Santini F, Vitti P, Ceccarini G, et al. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26:950-5. PubMed
  10. Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
  11. Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207. PubMed
  12. Kucuk U, Pham M, Raza Raja MH, Saad Shaukat MH, Clark R. Transient complete atrioventricular block associated with herbal supplement use. S D Med 2023;76(7):311-313.

See these in context on the Lemon Balm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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