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Dietary supplement

Lion's Mane Oh My! Peppermint Ingredients & Drug Interactions

by Mushroom Wisdom

Lion's Mane Oh My! Peppermint label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lion's Mane Oh My! Peppermint against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lion's Mane Oh My! Peppermint is a dietary supplement by Mushroom Wisdom with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, nerve health, mood and anxiety.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane Fruiting Body Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lion's Mane Oh My! Peppermint by Mushroom Wisdom

Ask about any prescription or over-the-counter medication and we check it for interactions with Lion's Mane Oh My! Peppermint by Mushroom Wisdom — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Lion's Mane Oh My! Peppermint by Mushroom Wisdom

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lion's mane mushroom fruiting body extract. The inactive ingredients are mannitol, corn starch, crospovidone, magnesium stearate, sucralose, silica, and peppermint oil — the last one likely responsible for the minty taste.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: oral health support.
  • We looked for evidence on: gum health, tooth health, mouth freshness.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence isn't established in our data for lion's mane on Alzheimer disease, anxiety, athletic performance, cancer, cognitive function, or cognitive impairment. We hold insufficient reliable evidence to rate it for any of these uses.

If you're considering this supplement for a specific reason, talk with your pharmacist about what the research actually shows right now.

The evidence, ingredient by ingredient Lion's Mane Mushroom

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lion's mane is generally well tolerated when taken by mouth. The most common side effects in trials were gastrointestinal discomfort, nausea, and skin rash.

That said, long-term supplement safety hasn't been well studied. The safety data doesn't support use during pregnancy or while breastfeeding, so you'll want to avoid it in those situations.

Side effects, ingredient by ingredient Lion's Mane Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check it with your pharmacist if you're on blood thinners or antiplatelet drugs like warfarin or aspirin (Moderate severity), diabetes medications (Moderate severity), or immunosuppressants (Moderate severity). These are the medication types lion's mane interacts with.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Lion's mane might appeal to you if you're interested in cognitive or immune support, but the evidence for those uses isn't yet strong enough for us to rate. If you take blood thinners, diabetes medications, or immunosuppressants, check with your pharmacist before starting.

Pregnant or breastfeeding? Skip this one.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lion's Mane Oh My! Peppermint, straight from the product label.

Brand Mushroom Wisdom
Barcode (UPC) 791014390903
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 302153
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lion's Mane Oh My! Peppermint by Mushroom Wisdom, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
30
UPC/BARCODE
791014390903
IngredientAmount% DV
Lion's Mane Fruiting Body Extract350 mg--

Other ingredients: Mannitol, Corn Starch, Crospovidone, Magnesium Stearate, Sucralose, Silica, Peppermint Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Science Complementing Ancient Wisdom

Formula

Made from Lion's Mane fruiting body, a famous edible mushroom

Fruiting Body Extract and Powder

Formulation

Quick dissolve form and no water needed Fresh your mouth and support oral health Manufactured in a certified cGMP facility

Oral Health Support

Suitable for Vegetarians

Contains No soy, dairy, artificial colors or preservatives

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 1 tablet 2-3 times a day. Place the quick dissolve tablet on the tongue until completely disintegrated before swallowing. No water needed.

Precautions

Warning: Keep out of reach of children.

Consult a physician before using if pregnant or nursing.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lion's Mane Oh My! Peppermint by Mushroom Wisdom label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lion's Mane Oh My! Peppermint label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lion's Mane Oh My! Peppermint by Mushroom Wisdom

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Lion's Mane Fruiting Body Extract

Interacts with
327 drugs
350 mg per serving Form: Hericium erinaceus Fruiting Body Extract

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...

Lion's Mane Fruiting Body Extract monograph & interactions

Other (inactive) ingredients: Mannitol, Corn Starch, Crospovidone, Magnesium Stearate, Sucralose, Silica, Peppermint Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lion's Mane Oh My! Peppermint by Mushroom Wisdom Drug Interactions

Want to check YOUR meds against Lion's Mane Oh My! Peppermint?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Lion's Mane Fruiting Body Extract 327

Individual Drug Interactions

The ingredients in Lion's Mane Oh My! Peppermint interact with 327 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lion's Mane Oh My! Peppermint interact with drugs. Each result below shows which ingredient is responsible. Lion's Mane Fruiting Body Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Lion's Mane Oh My! Peppermint with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lion's Mane Fruiting Body Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
Lion's Mane Fruiting Body Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lion's Mane Oh My! Peppermint, from the product label.

Mushroom Wisdom

See all Mushroom Wisdom products
Name
Mushroom Wisdom, Inc.
Street Address
1 Madison St., Bldg. F6
City
E. Rutherford
State
NJ
ZipCode
07073
Phone Number
800-747-7418
Web Address
www.mushroomwisdom.com
Pharmacist Counseling Corner

Lion's Mane Oh My! Peppermint by Mushroom Wisdom: Common Questions

Does Lion's Mane Oh My! Peppermint by Mushroom Wisdom interact with any medications?
Yes. Based on its ingredients, Lion's Mane Oh My! Peppermint has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lion's Mane Oh My! Peppermint contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does lion's mane mushroom actually do?
We don't have enough reliable evidence yet to rate lion's mane for Alzheimer disease, anxiety, athletic performance, cancer, cognitive function, or cognitive impairment. That doesn't mean it doesn't work — just that the science isn't settled.
What side effects should I expect?
Most people tolerate it well when taken by mouth. Some have reported gastrointestinal discomfort, nausea, or skin rash. It's generally well tolerated as a food, though long-term supplement safety hasn't been thoroughly studied.
Is it safe to take while pregnant or breastfeeding?
There isn't enough safety data for either situation, so it's best to avoid it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist if you have questions about your specific situation.
What's in this besides the mushroom extract?
The inactive ingredients are mannitol, corn starch, crospovidone, magnesium stearate, sucralose, silica, and peppermint oil — these are fillers, binders, and flavoring to make the tablet work and taste better.
Can I take this with my blood thinner?
That's a question for your pharmacist. Lion's mane may increase bleeding risk when used with blood thinners or antiplatelet drugs like aspirin or warfarin, so you need a yes or no specific to your medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lion's Mane Oh My! Peppermint is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lion's Mane Oh My! Peppermint label
Go deeper

The Full Monographs Behind Lion's Mane Oh My! Peppermint’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph →
Sources

Sources & How We Checked

Lion's Mane Oh My! Peppermint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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