Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Luteolin Complex Ingredients & Drug Interactions

by Swanson

Luteolin Complex label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Luteolin Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Luteolin Complex is a dietary supplement by Swanson with 2 active ingredients. Its ingredients are commonly taken for varicose veins and chronic venous insufficiency, hemorrhoids, easy bruising and fragile capillaries.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rutin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Luteolin Complex by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with Luteolin Complex by Swanson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Luteolin Complex by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Swanson's Luteolin Complex contains 2 active ingredients: rutin and luteolin. Rutin is a plant compound (a flavonoid) studied for its effects on aging skin, inflammatory bowel conditions, hemorrhoids, and diabetes, though the evidence for these uses isn't yet reliable enough to rate.

Luteolin is another plant flavonoid. The capsule also contains inactive ingredients (rice bran, hypromellose, calcium palmitate, and silica) that serve as fillers and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Brain and nervous system health.
  • We looked for evidence on: Neurological function, Cognitive support, Neural health, Neuroprotection.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We don't have enough reliable evidence to rate either rutin or luteolin for any of the conditions listed in the product's supplement facts — aging skin, autism spectrum disorder, inflammatory bowel disease, diabetes, exercise-related respiratory infections, or hemorrhoids. If you're considering this product for one of these uses, talk with your doctor or pharmacist about what the current evidence actually supports.

The evidence, ingredient by ingredient Rutin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rutin is generally well tolerated when used short-term or as a food ingredient, though long-term safety data at supplement doses are limited. Some people report headache, flushing, or rashes when taking rutin orally.

There isn't enough safety data for supplement doses during pregnancy, so the safety data advises against it unless your doctor advises otherwise. Safety during breastfeeding is also unknown, so it's best to avoid supplement doses.

We don't have pregnancy or breastfeeding safety data on file for luteolin.

Side effects, ingredient by ingredient Rutin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rutin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you use antidiabetes drugs (Moderate severity) — rutin may increase the risk of low blood sugar. We couldn't check luteolin for interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Luteolin Complex might interest people looking to explore plant compounds, but the evidence for its intended uses isn't yet established in our data. If you take an antidiabetes medication, check with your doctor or pharmacist before starting — there's a moderate-severity interaction risk.

Talk with your own healthcare provider about whether this product makes sense for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Luteolin Complex, straight from the product label.

Brand Swanson
Barcode (UPC) 087614028354
Net contents 30 Veggie Cap(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 308830
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Luteolin Complex by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
30
UPC/BARCODE
087614028354
IngredientAmount% DV
Rutin50 mg--
Luteolin50 mg--

Other ingredients: Rice Bran, Hypromellose, Calcium Palmitate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one veggie capsule per day with water.

Precautions

Warning: For adults only. Keep out of reach of children.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Brain and nervous system health

Formula

Luteolin Complex 100 mg per capsule

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Luteolin Complex by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Luteolin Complex label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Luteolin Complex by Swanson

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Rutin

Interacts with
86 drugs
50 mg per serving

Rutin is a plant flavonoid (often taken from buckwheat or citrus) that people use mainly for blood vessel and circulation problems like varicose veins...

Rutin monograph & interactions

Luteolin

50 mg per serving

Other (inactive) ingredients: Rice Bran, Hypromellose, Calcium Palmitate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Luteolin Complex by Swanson Drug Interactions

Want to check YOUR meds against Luteolin Complex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Rutin 86

Individual Drug Interactions

The ingredients in Luteolin Complex interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Luteolin Complex interact with drugs. Each result below shows which ingredient is responsible. Rutin

Each ingredient & the kinds of drugs it affects

For each ingredient in Luteolin Complex with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rutin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking rutin with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that rutin has hypoglycemic effects.

Likelihood Possible Evidence D
Rutin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Luteolin Complex, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Luteolin Complex by Swanson: Common Questions

Does Luteolin Complex by Swanson interact with any medications?
Yes. Based on its ingredients, Luteolin Complex has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Luteolin Complex contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
Rutin's safety data advise against supplement doses in pregnancy unless your doctor says otherwise. We don't have pregnancy safety information for luteolin. Talk with your doctor or pharmacist for personalized advice before taking this product during pregnancy.
Is this safe while breastfeeding?
Safety data on rutin during breastfeeding are unknown, so it's best to avoid supplement doses. We also don't have breastfeeding safety data for luteolin. Check with your doctor or pharmacist before taking this product while breastfeeding.
What side effects does rutin cause?
Some people report headache, flushing, or rashes when taking rutin orally. Most people tolerate it well, especially in short-term use.
Does this actually work for diabetes or skin aging?
We don't have enough reliable evidence to rate rutin or luteolin for diabetes, aging skin, or the other conditions this product mentions. If you're considering it for one of these uses, talk with your doctor about what evidence actually exists.
What's the difference between rutin and luteolin?
Both are plant flavonoids — compounds found naturally in plants. Rutin is the ingredient we have interaction and safety data for. Luteolin is the other active ingredient in this complex, but we don't hold detailed interaction data for it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Luteolin Complex is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Luteolin Complex label
Go deeper

The Full Monographs Behind Luteolin Complex’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rutin

Interacts with 86 drugs

Rutin is a plant flavonoid (often taken from buckwheat or citrus) that people use mainly for blood vessel and circulation problems like varicose veins and hemorrhoids. The evidence is limite...

Read the full Rutin monograph →
Sources

Sources & How We Checked

Luteolin Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rutin 2 references
  1. Mehta DK (Ex Ed). British National Formulary, Number 37. British Medical Association and Royal Pharmaceutical Society of Great Britain: London, England, March 1999.
  2. Sun C, Wang L, Sun J, Wang Z, Tang Z. Hypoglycemic and hypolipidemic effects of rutin on hyperglycemic rats. J Tradit Chin Med. 2020;40(4):640-645.

See these in context on the Rutin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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