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Dietary supplement

Lycopene 5000 mcg Ingredients & Drug Interactions

by Quest

Lycopene 5000 mcg label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lycopene 5000 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lycopene 5000 mcg is a dietary supplement by Quest with 1 active ingredient. Its ingredients are commonly taken for heart health support, prostate health, antioxidant support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lycopene 5000 mcg by Quest

Ask about any prescription or over-the-counter medication and we check it for interactions with Lycopene 5000 mcg by Quest — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lycopene 5000 mcg by Quest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Tomato (Lycopersicon esculentum) fruit extract” is listed as a grouped ingredient — the label gives one combined amount (71.40 mg) without saying how much of each component you get.

This product contains one active ingredient: lycopene, a plant pigment extracted from tomato fruit. Lycopene is a carotenoid — a type of antioxidant found naturally in red and pink fruits and vegetables.

The softgel also includes inactive ingredients: soybean oil, corn oil, beeswax, gelatin, and glycerin, which help deliver and protect the lycopene.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: antioxidant support for a healthy prostate.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostate cancer, prostate health, prostate function.
  • The strongest evidence on file: Lycopene is rated "Possibly Effective" for Prostate cancer (Natural Medicines).
  • Also on file: Lycopene is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS).

Lycopene is possibly effective for prostate cancer — meaning some evidence supports it, but more research is needed. For bladder cancer, diabetes, and other conditions listed, the evidence is either possibly ineffective or too limited to say.

The data we hold rates the evidence for high cholesterol (hyperlipidemia), ALS, and exercise-induced asthma as insufficient to draw a conclusion.

The evidence, ingredient by ingredient Tomato Lycopene

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lycopene from food is considered safe, and supplement doses are generally well tolerated. That said, gastrointestinal side effects from supplements can include diarrhea, gas, bloating, nausea, vomiting, indigestion, and loss of appetite.

For pregnancy, the safety data advises against supplements unless your doctor advises otherwise — food amounts are fine. Breastfeeding mothers should also avoid supplements due to insufficient safety data, though food amounts are okay.

Side effects, ingredient by ingredient Tomato Lycopene

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lycopene.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check with your doctor or pharmacist if you take blood thinners (anticoagulants) or antiplatelet drugs like aspirin, warfarin, or clopidogrel — lycopene may increase your bleeding risk. This product's interactions are Moderate in severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Quest's Lycopene is worth considering if you're interested in prostate health and can take it safely with your other medications. If you use any blood thinners or antiplatelet drugs, you'll want to clear it with your doctor or pharmacist first.

Start the conversation there, and let them weigh the benefits against your individual health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lycopene 5000 mcg, straight from the product label.

Brand Quest
Barcode (UPC) 058371219880
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 24060
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Adult Male (18-50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lycopene 5000 mcg by Quest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Softgel(s)
Maximum serving Sizes:
4 Softgel(s)
UPC/BARCODE
058371219880
IngredientAmount% DV
Lycopene5000 mcg--
Tomato (Lycopersicon esculentum) fruit extract71.4 mg--

Other ingredients: Soybean Oil, Corn Oil, yellow Beeswax, Gelatin, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

KEEP OUT OF REACH OF CHILDREN.

DO NOT USE IF SEAL UNDER CAP IS BROKEN.

Risk Information: Do not use if pregnant or breastfeeding.

General Statements

WELLNESS

A Proud Canadian Company

Formula

Antioxidant support for a healthy prostate

Formulation

No artificial colours, flavours or preservatives

This product does not contain corn, dairy, egg, gluten, shellfish or sulfites.

Seals/Symbols

PREMIUM - QUALITY ASSURED

{Recycle}

SunOpta A healthy products company

General

338421.01-05

Suggested/Recommended/Usage/Directions

Recommended Use: Antioxidant support for a healthy prostate. Recommended Dose (Adults): Take 3 to 4 softgels daily. For optimal results, take with main meal.

Storage

STORE IN A COOL, DRY PLACE.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lycopene 5000 mcg by Quest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lycopene 5000 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lycopene 5000 mcg by Quest

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Tomato (Lycopersicon esculentum) fruit extract

No known
interactions
71.4 mg per serving

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people...

Tomato (Lycopersicon esculentum) fruit extract monograph & interactions

Other (inactive) ingredients: Soybean Oil, Corn Oil, Yellow Beeswax, Gelatin, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lycopene 5000 mcg by Quest Drug Interactions

Want to check YOUR meds against Lycopene 5000 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Lycopene 5000 mcg interact with 122 drugs. Click any drug to see the details.

0 of the 1 ingredient in Lycopene 5000 mcg interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Lycopene 5000 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Lycopene 5000 mcg, from the product label.

Quest

See all Quest products
Name
SunOpta Inc.
Street Address
6 Commerce Crescent
City
Acton
State
ON
ZipCode
L7J 2X3
Pharmacist Counseling Corner

Lycopene 5000 mcg by Quest: Common Questions

Does Lycopene 5000 mcg by Quest interact with any medications?
Yes. Based on its ingredients, Lycopene 5000 mcg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lycopene 5000 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will lycopene help my prostate?
The evidence shows it's possibly effective for prostate cancer, meaning some research supports it but we need more studies to be sure. It won't work for other conditions we tested, like bladder cancer or diabetes.
What side effects might I get?
The most common are gastrointestinal — think diarrhea, gas, bloating, nausea, or indigestion. Most people tolerate it well, but these can happen.
Is it safe if I'm pregnant or breastfeeding?
The safety data advises against lycopene supplements in both pregnancy and while breastfeeding unless your doctor says it's okay. Food amounts are fine; it's the high-dose supplements that lack enough safety study. Talk with your doctor or pharmacist about your specific situation.
Can I take this with my aspirin?
Not without checking first. Lycopene may increase bleeding risk with aspirin and other blood thinners. Your doctor or pharmacist needs to review this combination for you.
What exactly is lycopene?
It's a red plant pigment — a type of antioxidant — found naturally in tomatoes and other red fruits and vegetables. This softgel delivers a concentrated dose extracted from tomato fruit.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lycopene 5000 mcg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lycopene 5000 mcg label
Go deeper

The Full Monographs Behind Lycopene 5000 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tomato

Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people. Concentrated tomato or lycopene supple...

Read the full Tomato monograph → Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph →
Sources

Sources & How We Checked

Lycopene 5000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
  6. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
  7. Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Tomato 3 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Asero R, Mistrello G, Amato S. Airborne allergy to tomato proteins. Allergy. 2010;65(12):1626-7. PubMed
  3. Friedman M. Tomato Glycoalkaloids: Role in the Plant and in the Diet. J Agric Food Chem. 2002;50(21):5751-80. PubMed

See these in context on the Tomato monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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