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Dietary supplement

Malic Acid 800 mg Ingredients & Drug Interactions

by Nature's Life

Malic Acid 800 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Malic Acid 800 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Malic Acid 800 mg is a dietary supplement by Nature's Life with 1 active ingredient. Its ingredients are commonly taken for fibromyalgia symptoms, muscle pain and fatigue, dry mouth (used in some lozenges).Based on those ingredients, 172 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Malic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Malic Acid 800 mg by Nature's Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Malic Acid 800 mg by Nature's Life — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Malic Acid 800 mg by Nature's Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: malic acid at 800 mg per capsule. Malic acid is an organic compound found naturally in fruits like apples and gives them their tart taste.

The capsule itself is made from vegetable cellulose, with stearic acid and magnesium stearate as inactive ingredients to help bind and process the supplement.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: natural fruit acid mineral chelating agent.
  • We looked for evidence on: Dry mouth, Fibromyalgia, Fatigue, muscle pain, energy.
  • The strongest evidence on file: Malic Acid is rated "Possibly Effective" for Dry mouth (Natural Medicines).
  • Also on file: Malic Acid is rated "Insufficient Reliable Evidence To Rate" for Fatigue, Fibromyalgia.

The evidence is mixed. Malic acid is possibly effective for dry mouth — that's the one use where we have some supporting data.

For acne, GERD (acid reflux), fatigue, fibromyalgia, and psoriasis, the evidence isn't established in the data we hold, so we can't say whether it works for those purposes.

The evidence, ingredient by ingredient Malic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Malic acid taken by mouth appears to be well tolerated overall, though supplement doses haven't been studied as thoroughly as food amounts. Diarrhea and nausea have been reported in people taking a combination product that paired malic acid with magnesium, though it's unclear whether malic acid or the magnesium caused those effects — magnesium is known to have a laxative effect at higher doses.

Safety information for supplement-level doses is limited, so caution is advised if you're considering this product. Pregnancy and lactation: malic acid is rated as likely safe during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Malic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Malic Acid.
  • The most serious interaction on file is rated Moderate.
  • For scale: 172 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check your blood pressure medications (antihypertensive drugs) with your doctor or pharmacist — malic acid may increase the risk of your blood pressure dropping too low. We also held incomplete interaction data on some of the inactive ingredients, so running your full medication list through the checker on this page is a good idea.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood pressure medication, check with your doctor or pharmacist before starting this supplement — malic acid may lower your blood pressure further. The evidence supports it possibly for dry mouth, but not for other common uses.

Malic acid appears generally well tolerated by mouth, though long-term safety data at supplement doses is sparse. Talk over whether this makes sense for your situation with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Malic Acid 800 mg, straight from the product label.

Brand Nature's Life
Barcode (UPC) 040647004481
Net contents 100 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 278250
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Malic Acid 800 mg by Nature's Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
040647004481
IngredientAmount% DV
Malic Acid800 mg--

Other ingredients: Vegetable Cellulose Capsule, Stearic Acid, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Nature's Life Sun Food Energy

Quality you can trust

Formula

Mineral chelating agent Natural fruit acid

Discussion: Malic Acid is a fruit acid. Its ability to bond with alkaline minerals such as calcium and magnesium may help to improve the absorption of these important nutrients.

Suggested/Recommended/Usage/Directions

1 Daily

Directions: Use only as directed. Take one (1) vegetarian capsule daily with food.

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: Do not use if safety seal is broken or missing.

Keep out of reach of children.

Keep your licensed health care practitioner informed when using this product.

Storage

Store in a cool, dry place.

Formulation

Nature's Life guarantees that no ingredients other than those listed on this label have been added to this product. This quality Nature's Life product meets our Quality Assurance Procedures and Good Manufacturing Practices.

Suitable for Vegetarians

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure of prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Malic Acid 800 mg by Nature's Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Malic Acid 800 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Malic Acid 800 mg by Nature's Life

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Malic Acid

Interacts with
172 drugs
800 mg per serving

Malic acid is a natural acid found in apples and other fruits, often combined with magnesium in supplements marketed for fibromyalgia and muscle pain....

Malic Acid monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose Capsule, Stearic Acid, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Malic Acid 800 mg by Nature's Life Drug Interactions

Want to check YOUR meds against Malic Acid 800 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
172Drugs
172 Moderate

Ingredients driving the most interactions

Malic Acid 172

Individual Drug Interactions

The ingredients in Malic Acid 800 mg interact with 172 drugs. Click any drug to see the details.

1 of the 1 ingredient in Malic Acid 800 mg interact with drugs. Each result below shows which ingredient is responsible. Malic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Malic Acid 800 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Malic Acid1 drug type · 172 drugs

Antihypertensive Drugs

Theoretically, malic acid might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that malic acid isolated from tagetes roots can reduce mean arterial blood pressure.

Likelihood Possible Evidence D
Malic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Malic Acid 800 mg, from the product label.

Nature's Life

See all Nature's Life products
Name
NutraPure, Inc.
Web Address
www.reachforlife.com
Pharmacist Counseling Corner

Malic Acid 800 mg by Nature's Life: Common Questions

Does Malic Acid 800 mg by Nature's Life interact with any medications?
Yes. Based on its ingredients, Malic Acid 800 mg has a known interaction with 172 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Malic Acid 800 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is malic acid safe to take while pregnant or breastfeeding?
Yes, malic acid is rated as likely safe during pregnancy and lactation according to the data we hold. That said, any decision about supplements during pregnancy or breastfeeding is personal — talk it over with your own doctor or midwife to make sure it fits your situation.
What side effects might I experience if I take this?
Malic acid taken by mouth is generally well tolerated. Some people in studies reported diarrhea and nausea when taking a combination product with malic acid and magnesium, though it's unclear which ingredient caused those effects.
Does malic acid actually help with fatigue or fibromyalgia?
The evidence isn't established in the data we hold for either of those uses, so we can't say whether it works for fatigue or fibromyalgia.
Will this help my dry mouth?
Malic acid is possibly effective for dry mouth — that's the one use where we have supporting evidence. Whether it'll help your specific situation is something to discuss with your doctor or pharmacist.
What's in the capsule besides malic acid?
The capsule is made from vegetable cellulose and contains stearic acid and magnesium stearate, which are inactive ingredients used to bind and process the supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Malic Acid 800 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Malic Acid 800 mg label
Go deeper

The Full Monographs Behind Malic Acid 800 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Malic Acid

Interacts with 172 drugs

Malic acid is a natural acid found in apples and other fruits, often combined with magnesium in supplements marketed for fibromyalgia and muscle pain. The evidence for its health benefits is...

Read the full Malic Acid monograph →
Sources

Sources & How We Checked

Malic Acid 800 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Malic Acid 7 references
  1. Russell IJ, Michalek JE, Flechas JD, Abraham GE. Treatment of fibromyalgia syndrome with Super Malic: a randomized, double blind, placebo controlled, crossover pilot study. J Rheumatol 1995;22:953-8.
  2. Fiume, Z. Final report on the safety assessment of malic acid and sodium malate. Int J Toxicol 2001;20 Suppl 1:47-55. PubMed
  3. Electronic Code of Federal Regulations. Title 21. Part 184 - Direct Food Substances Affirmed as Generally Recognized as Safe. Available at: http://www.ecfr.gov/cgi-bin/text-idx?c=ecfr&sid=786bafc6f6343634fbf79fcdca7061e1&rgn=div5&view=text&node=21:3.0.1.1
  4. Saleem R, Ahmad M, Naz A, et al. Hypotensive and toxicological study of citric acid and other constituents from Tagetes patula roots. Arch Pharm Res 2004;27(10):1037-42.
  5. Chiriac A, Brzezinski P. Topical malic acid in combination with citric acid: an option to treat recalcitrant warts. Dermatol Ther. 2015;28(6):336-8. PubMed
  6. CFR - Code of Federal Regulations Title 21 SUBCHAPTER B. 184.1069 Malic Acid. Food and Drug Administration Department Of Health And Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1069.
  7. Amended Safety Assessment of Malic Acid and Sodium Malate as Used in Cosmetics. Cosmetic Ingredient Review Expert Panel. Updated May 19, 2017. http://www.cir-safety.org/sites/default/files/malic%20acid.pdf. Accessed January 24, 2018.

See these in context on the Malic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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