Mojo Ingredients & Drug Interactions
by Kinobody
What is this page for?
First and foremost: checking Mojo against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Mojo is a dietary supplement by Kinobody with 5 active ingredients. Its ingredients are commonly taken for zinc deficiency, immune support, cold symptoms.Based on those ingredients, 1,115 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Coleus forskohlii Root Extract, Magnesium, Eurycoma longifolia Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Mojo by Kinobody
Ask about any prescription or over-the-counter medication and we check it for interactions with Mojo by Kinobody — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Mojo by Kinobody
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Mojo contains five active ingredients: zinc, boron, magnesium, Coleus forskohlii root extract, and Eurycoma longifolia root extract. Zinc is used to correct deficiency and may help with conditions like acne and age-related macular degeneration.
Boron supports bone health and may help with certain types of fungal infections. Magnesium plays roles in muscle and nerve function and has established effectiveness for constipation and dyspepsia (indigestion).
Coleus forskohlii contains forskolin, a compound that may affect heart and lung function, though the evidence remains limited. Eurycoma longifolia is traditionally used to support sexual function and athletic performance.
The product also contains inactive ingredients — cellulose, magnesium stearate, silica, and hydroxypropyl methylcellulose — that serve as binders and fillers.
Does it work?
Not established
Zinc is effective for zinc deficiency and likely effective for Wilson disease; it's possibly effective for acne, acrodermatitis enteropathica (a rare genetic condition), age-related macular degeneration, and diabetes support. Boron is likely effective for boron deficiency and possibly effective for vaginal yeast infections and radiation-related skin damage.
Magnesium is effective for constipation and indigestion, and for low blood magnesium; it's also effective for preventing pre-eclampsia in pregnancy. Coleus forskohlii and Eurycoma longifolia have insufficient evidence or are not well studied for their marketed uses — the data we hold does not establish their effectiveness for angina, asthma, heart failure, eczema, sexual desire, athletic performance, back pain, or diabetes.
How safe is it?
Well-documented data
Zinc is generally well tolerated at recommended doses (below 40 mg daily for adults), but high doses carry risks of nausea, diarrhea, metallic taste, and abdominal cramps; very high long-term use may lead to copper deficiency. Boron is generally safe at low doses but should be avoided in pregnancy and while breastfeeding — high doses are toxic.
Magnesium is generally safe for healthy adults at normal amounts, though it may cause diarrhea, nausea, or gastrointestinal irritation; the data advises caution with supplements during pregnancy and breastfeeding, so check with your doctor. Coleus forskohlii appears well tolerated in short-term studies but is not well studied long-term, may lower blood pressure, and should be avoided in pregnancy and while breastfeeding due to insufficient safety data.
Eurycoma longifolia is generally tolerated short-term but has uncertain long-term safety; it may increase testosterone, which carries risks of acne and liver effects if levels go too high. It should also be avoided during pregnancy and breastfeeding.
Meds to double-check
Major interaction found
Before taking Mojo, check with your pharmacist if you take levodopa/carbidopa (Parkinson's), nitrates or calcium channel blockers (heart), quinolone or tetracycline antibiotics, cephalexin (Keflex), penicillamine (Cuprimine), ritonavir or integrase inhibitors (HIV), skeletal muscle relaxants, potassium-sparing diuretics, antacids, sulfonylureas (diabetes), bisphosphonates (bone), antihypertensive drugs, anticoagulants or antiplatelet drugs, warfarin (Coumadin), propranolol (Inderal), or any other prescription medications. The interactions range from Major to Minor severity.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
Mojo may be worth considering if you have a zinc, boron, or magnesium deficiency and your doctor confirms one. However, this product interacts with a large number of prescription medications — particularly heart drugs, antibiotics, Parkinson's medications, and HIV treatments — so you must check your exact medications with the tool on this page before starting.
If you take any prescription or over-the-counter drugs, talk to your pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Mojo, straight from the product label.
| Brand | Kinobody |
|---|---|
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2024 |
| DSLD ID | 309992 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Mojo by Kinobody, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Zinc | 15 mg | 136% |
| Boron | 6 mg | -- |
| Magnesium | 200 mg | 48% |
| Coleus forskohlii Root Extract | 250 mg | -- |
| Eurycoma longifolia Root Extract | 200 mg | -- |
Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Kino Mojo is an all natural supplement designed to promote optimal testosterone levels.
All natural Testosterone support
5 key scientifically backed ingredients
Fasting friendly
Soy free Dairy free Gluten free Nut free
Formula
Kino Mojo consists of three key mineral and two scientifically backed herbs that all work together to elevate your natural testosterone levels to their potential. The result is greater confidence, ambition, virility and performance.
Suggested/Recommended/Usage/Directions
For best results take Kino Mojo for 5-12 weeks to maximize your natural testosterone levels. Kino Mojo is best used in combination with optimal sleep, vitamin D, proper nutrition and a solid training program. Suggested Usage: As a dietary supplement, take three (3) capsules anytime during the day with or without food. Do not exceed recommended dosage.
Precautions
Do not exceed recommended dosage.
Warning: Check with a qualified healthcare professional before using this product if you are under 18 years of age, pregnant, or nursing a baby or if you have any known or suspected medical condition(s) and/or are taking any prescription or OTC medications. Keep out of reach of children.
Warning: Check with a qualified healthcare professional before using this product if you are under 18 years of age, pregnant, or nursing a baby or if you have any known or suspected medical condition(s) and/or are taking any prescription or OTC medications.
Manufactured in a facility and equipment that handles: Eggs, wheat, milk, tree nuts, peanuts, soybeans, crustacean shellfish and fish.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
30 day supply
Seals/Symbols
Assembled in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Mojo by Kinobody label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Mojo by Kinobody
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Zinc
Interacts with67 drugs
Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but suppleme...
Zinc monograph & interactionsBoron
No knowninteractions
Boron is a trace mineral found in many plant foods and sold as a supplement, mainly promoted for bone, joint, and hormone health. The human evidence f...
Boron monograph & interactionsMagnesium
Interacts with295 drugs
Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preven...
Magnesium monograph & interactionsColeus forskohlii Root Extract
Interacts with915 drugs
Coleus is a plant from the mint family whose root contains a compound called forskolin, often marketed for weight loss, asthma, and heart health. Whil...
Coleus forskohlii Root Extract monograph & interactionsEurycoma longifolia Root Extract
Interacts with248 drugs
Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...
Eurycoma longifolia Root Extract monograph & interactionsOther (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Mojo by Kinobody Drug Interactions
HelloPharmacist Interaction Report
Mojo by Kinobody contains five active ingredients, and we've found documented interactions with a substantial number of medications.
The most serious concern is magnesium's Major-severity interaction with levodopa/carbidopa (used for Parkinson's disease) — magnesium can reduce levodopa levels by up to 35%, which may blunt symptom control. Coleus forskohlii also carries two Major-severity interactions: it may dangerously amplify the effects of nitrates and calcium channel blockers, both used for heart conditions.
Read the full breakdown — every affected drug type, severity by severity
Zinc moderately interacts with quinolone antibiotics, cephalexin, tetracycline antibiotics, penicillamine, ritonavir (an HIV medication), cisplatin (a chemotherapy drug), integrase inhibitors, and bictegravir/emtricitabine/tenofovir alafenamide — all by reducing absorption or drug levels. Magnesium also has Moderate interactions with skeletal muscle relaxants, potassium-sparing diuretics, calcium channel blockers, antacids, sulfonylureas (diabetes drugs), quinolone antibiotics, and bisphosphonates (bone drugs).
Coleus carries Moderate interactions with antihypertensive drugs, CYP2C9 and CYP3A4 substrates, anticoagulants and antiplatelet drugs, and warfarin.
Eurycoma longifolia has Moderate interaction with propranolol (a beta blocker) and Minor interactions with several CYP450 substrates and testosterone. Altogether, these interactions span 1,102 individual medications.
Use the medication checker below to see if any of your prescriptions are on this list before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Mojo?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Mojo interact with 1,115 drugs. Click any drug to see the details.
4 of the 5 ingredients in Mojo interact with drugs. Each result below shows which ingredient is responsible. Coleus forskohlii Root Extract Magnesium Eurycoma longifolia Root Extract Zinc
AmlodipineNorliqva
How Amlodipine interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Root Extract + Amlodipine interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCalcium Channel Blockers, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Amlodipine Benzoate interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractAntihypertensive Drugs, Calcium Channel Blockers +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Root Extract + Amlodipine Besilate interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Root Extract + Amlodipine Besylate interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCalcium Channel Blockers, Antihypertensive Drugs +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Amlodipine Besylate, Benazepril interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCalcium Channel Blockers, Antihypertensive Drugs +2 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Amlodipine, Celecoxib interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Amlodipine, Celecoxib interactionBenserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Benserazide, Levodopa interactionBepridilVascor
How Bepridil interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCalcium Channel Blockers, Cytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Bepridil interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Bepridil interactionCarbidopaLodosyn
How Carbidopa interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Carbidopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Carbidopa, Levodopa, Entacapone interactionDiltiazemAdizem-SR, Adizem-XL, Angitil SR, Angitil XL, Calcicard CR, Cardizem +23 more
How Diltiazem interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractAntihypertensive Drugs, Calcium Channel Blockers +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Root Extract + Diltiazem interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Diltiazem interactionDiltiazem, EnalaprilTeczem
How Diltiazem, Enalapril interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Calcium Channel Blockers +1 Major
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Root Extract + Diltiazem, Enalapril interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Diltiazem, Enalapril interactionEnalapril Maleate, FelodipineLexxel
How Enalapril Maleate, Felodipine interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Root Extract + Enalapril Maleate, Felodipine interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Enalapril Maleate, Felodipine interactionFelodipinePlendil, Renedil
How Felodipine interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCalcium Channel Blockers, Antihypertensive Drugs +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Felodipine interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Felodipine interactionGlyceryl TrinitrateNitronal
How Glyceryl Trinitrate interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Glyceryl Trinitrate interactionIsosorbide DinitrateAngitak, Cedocard Retard, Isoket, Isoket Retard, Isordil
How Isosorbide Dinitrate interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Isosorbide Dinitrate interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractNitrates, Antihypertensive Drugs Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Isosorbide Dinitrate, Hydralazine interactionIsosorbide MononitrateAngeze, Angeze SR, Chemydur 60XL, Dynamin, Elantan, Elantan LA +13 more
How Isosorbide Mononitrate interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Isosorbide Mononitrate interactionIsradipineDynacirc CR
How Isradipine interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Root Extract + Isradipine interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Isradipine interactionLercanidipine HydrochlorideZanidip
How Lercanidipine Hydrochloride interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCalcium Channel Blockers, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Lercanidipine Hydrochloride interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Lercanidipine Hydrochloride interactionLevamlodipineConjupri
How Levamlodipine interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Calcium Channel Blockers +1 Major
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Root Extract + Levamlodipine interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Levamlodipine interactionLevodopaInbrija, Larodopa
How Levodopa interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
MagnesiumLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium + Levodopa, Carbidopa interactionNicardipineCardene, Cardene IV, Cardene SR
How Nicardipine interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCalcium Channel Blockers, Antihypertensive Drugs +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Nicardipine interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Nicardipine interactionNicorandilAprior, Dancor, Ikorel, Sigmart, Zynicor
How Nicorandil interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Nicorandil interactionNifedipineAdalat, Adalat CC, Adalat LA, Adalat PA, Adalat Retard, Adalat XL +15 more
How Nifedipine interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Major
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Root Extract + Nifedipine interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Nifedipine interactionNisoldipineSular
How Nisoldipine interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCalcium Channel Blockers, Antihypertensive Drugs +1 Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Nisoldipine interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Nisoldipine interactionNitrendipineCardif
How Nitrendipine interacts with Mojo — through 2 ingredients. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractCalcium Channel Blockers, Cytochrome P450 3a4 (cyp3a4) Substrates Major
Interaction Summary
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Nitrendipine interactionMagnesiumCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium + Nitrendipine interactionNitroglycerinGonitro, Nitro Time, Nitro-Bid, Nitrocine Timecaps, Nitrogard, Nitrogard SR +7 more
How Nitroglycerin interacts with Mojo — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Root ExtractNitrates Major
Interaction Summary
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Read the full Coleus Forskohlii Root Extract + Nitroglycerin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Mojo with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Coleus forskohlii Root Extract
Calcium Channel Blockers
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and calcium channel blockers both cause coronary vasodilatory effects.
Nitrates
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and nitrates both cause coronary vasodilatory effects.
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of coleus and anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro and animal research shows that forskolin, a constituent of coleus, can inhibit platelet aggregation and adhesion.
Antihypertensive Drugs
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Animal research shows that forskolin, a constituent of coleus, may lower blood pressure.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, taking coleus may affect drugs metabolized by CYP2C9 and increase the risk of adverse effects or reduce the effectiveness.
Research on the effect of coleus on CYP2C9 is conflicting. Some animal research shows that coleus extract can induce CYP2C9, while in vitro research shows that coleus can inhibit CYP2C9. Until more is known, advise patients that taking coleus might increase or decrease levels of drugs metabolized by CYP2C9.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
In vitro research shows that coleus can activate the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of coleus and other drugs affected by these enzymes.
Warfarin (Coumadin)
Theoretically, taking coleus may affect the metabolism of warfarin and increase the risk of adverse effects or reduce the effectiveness.
Some animal research shows that coleus extract can induce cytochrome P450 2C9 (CYP2C9), an enzyme that metabolizes warfarin. However, other in vitro research shows that coleus can inhibit CYP2C9. Theoretically, taking coleus with drugs metabolized by CYP2C9 might affect drug levels and the risk of adverse effects. Until more is known, advise patients that taking coleus might increase or decrease levels of warfarin.
Magnesium
Levodopa/Carbidopa (Sinemet)
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Clinical research in healthy volunteers shows that taking magnesium oxide 1000 mg with levodopa 100 mg/carbidopa 10 mg reduces the area under the curve (AUC) of levodopa by 35% and of carbidopa by 81%. In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa.
Aminoglycoside Antibiotics
Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Both aminoglycosides and magnesium reduce presynaptic acetylcholine release, which can lead to neuromuscular blockade and possible paralysis. This is most likely to occur with high doses of magnesium given intravenously.
Antacids
Use of acid reducers may reduce the laxative effect of magnesium oxide.
A retrospective analysis shows that, in the presence of H2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs), a higher dose of magnesium oxide is needed for a laxative effect. This may also occur with antacids. Under acidic conditions, magnesium oxide is converted to magnesium chloride and then to magnesium bicarbonate, which has an osmotic laxative effect. By reducing acidity, antacids may reduce the conversion of magnesium oxide to the active bicarbonate salt.
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)
Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after magnesium containing products.
Bisphosphonates
Magnesium can decrease absorption of bisphosphonates.
Cations, including magnesium, can decrease bisphosphonate absorption. Advise patients to separate doses of magnesium and these drugs by at least 2 hours.
Calcium Channel Blockers
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers. Severe hypotension and neuromuscular blockades may occur when nifedipine is used with intravenous magnesium, although some contradictory evidence suggests that concurrent use of magnesium with nifedipine does not increase the risk of neuromuscular weakness. High doses of magnesium could theoretically have additive effects with other calcium channel blockers.
Digoxin
Magnesium salts may reduce absorption of digoxin.
Clinical evidence suggests that treatment with oral magnesium hydroxide or magnesium trisilicate reduces absorption of digoxin from the intestines. This may reduce the blood levels of digoxin and decrease its therapeutic effects.
Potassium-Sparing Diuretics
Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.
Quinolone Antibiotics
Magnesium decreases absorption of quinolones.
Magnesium can form insoluble complexes with quinolones and decrease their absorption. Advise patients to take these drugs at least 2 hours before, or 4 to 6 hours after, magnesium supplements.
Skeletal Muscle Relaxants
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Parenteral magnesium shortens the time to onset of skeletal muscle relaxants by about 1 minute and prolongs the duration of action by about 2 minutes. Magnesium potentiates the effects of skeletal muscle relaxants by decreasing calcium-mediated release of acetylcholine from presynaptic nerve terminals, reducing postsynaptic sensitivity to acetylcholine, and having a direct effect on the membrane potential of myocytes. Magnesium also has vasodilatory actions and increases cardiac output, allowing a greater amount of muscle relaxant to reach the motor end plate. A clinical study found that low-dose rocuronium (0.45 mg/kg), when given after administration of magnesium 30 mg/kg over 10 minutes, has an accelerated onset of effect, which matches the onset of effect seen with a full-dose rocuronium regimen (0.6 mg/kg). In another clinical study, onset times for rocuronium doses of 0.3, 0.6, and 1.2 mg/kg were 86, 76, and 50 seconds, respectively, when given alone, but were reduced to 66, 44, and 38 seconds, respectively, when the doses were given after a 15-minute infusion of magnesium sulfate 60 mg/kg. Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time. It does not affect the activity of subsequently administered neostigmine.
Sulfonylureas
Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Clinical research shows that administration of magnesium hydroxide with glyburide increases glyburide absorption, increases maximal insulin response by 35-fold, and increases the risk of hypoglycemia, when compared with glyburide alone. A similar interaction occurs between magnesium hydroxide and glipizide. The mechanism of this effect appears to be related to the elevation of gastrointestinal pH by magnesium-based antacids, increasing solubility and enhancing absorption of sulfonylureas.
Tetracycline Antibiotics
Magnesium decreases absorption of tetracyclines.
Magnesium can form insoluble complexes with tetracyclines in the gut and decrease their absorption and antibacterial activity. Advise patients to take these drugs 1 hour before or 2 hours after magnesium supplements.
Anticoagulant/Antiplatelet Drugs
Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
In vitro evidence shows that magnesium sulfate inhibits platelet aggregation, even at low concentrations. Some preliminary clinical evidence shows that infusion of magnesium sulfate increases bleeding time by 48% and reduces platelet activity. However, other clinical research shows that magnesium does not affect platelet aggregation, although inhibition of platelet-dependent thrombosis can occur.
Gabapentin (Neurontin)
Gabapentin absorption can be decreased by magnesium.
Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to take gabapentin at least 2 hours before, or 4 to 6 hours after, magnesium supplements.
Sevelamer (Renagel, Renvela)
Sevelamer may increase serum magnesium levels.
In patients on hemodialysis, sevelamer use was associated with a 0.28 mg/dL increase in serum magnesium. The mechanism of this interaction remains unclear.
Eurycoma longifolia Root Extract
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Zinc
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)
Theoretically, zinc might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after zinc containing products.
Cephalexin (Keflex)
Zinc might decrease cephalexin levels by chelating with cephalexin in the gut and preventing its absorption.
A pharmacokinetic study shows that zinc sulfate 250 mg taken concomitantly with cephalexin 500 mg decreases peak levels of cephalexin by 31% and reduces the exposure to cephalexin by 27%. Also, taking zinc sulfate 3 hours before cephalexin decreases peak levels of cephalexin by 11% and reduces the exposure to cephalexin by 18%. By decreasing cephalexin levels, zinc might increase the risk of treatment failure. This effect does not occur when zinc is taken 3 hours after the cephalexin dose. To avoid an interaction, advise patients take zinc sulfate 3 hours after taking cephalexin.
Cisplatin (Platinol-Aq)
Theoretically, zinc might interfere with the therapeutic effects of cisplatin.
Animal research suggests that zinc stimulates tumor cell production of the protein metallothionein, which binds and inactivates cisplatin. It is not known whether zinc supplements or high dietary zinc intake can cause clinically significant interference with cisplatin therapy. Cisplatin might also increase zinc excretion.
Integrase Inhibitors
Theoretically, taking zinc along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Zinc is a divalent cation. Pharmacokinetic studies have shown that other divalent cations such as calcium and iron can decrease blood levels of the integrase inhibitor dolutegravir through chelation.
Penicillamine (Cuprimine, Depen)
Zinc might reduce the levels and clinical effects of penicillamine.
By forming an insoluble complex with penicillamine, zinc interferes with penicillamine absorption and activity. Zinc supplements reduce the efficacy of low-dose penicillamine (0.5-1 gram/day), but do not seem to affect higher doses (1-2.75 gram/day), provided dosing times are separated. Advise patients to take zinc and penicillamine at least 2 hours apart.
Quinolone Antibiotics
Zinc can decrease the levels and clinical effects of quinolones antibiotics.
Quinolones form complexes with zinc in the gastrointestinal tract, reducing absorption of both the quinolone and zinc if taken at the same time. Advise patients to take these drugs at least 2 hours before, or 4-6 hours after, zinc supplements.
Ritonavir (Norvir)
Zinc modestly reduces levels of ritonavir.
Clinical research shows that zinc might reduce serum ritonavir levels by chelating with ritonavir in the gut and preventing its absorption. In patients with HIV, ritonavir is taken with atazanavir to prevent the metabolism and increase the effects of atazanavir. A pharmacokinetic study shows that, in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate (Solvazinc tablets) 125 mg as a single dose or as multiple daily doses for 2 weeks reduces plasma levels of ritonavir by about 16%. However, atazanavir levels still remains high enough to prevent HIV virus replication. Therefore, the decrease in ritonavir levels is not likely to be clinically significant.
Tetracycline Antibiotics
Zinc might reduce levels of tetracycline antibiotics.
Tetracyclines form complexes with zinc in the gastrointestinal tract, which can reduce absorption of both the tetracycline and zinc when taken at the same time. Taking zinc sulfate 200 mg with tetracycline reduces absorption of the antibiotic by 30% to 40%. Demeclocycline and minocycline cause a similar interaction. However, doxycycline does not seem to interact significantly with zinc. Advise patients to take tetracyclines at least 2 hours before, or 4-6 hours after, zinc supplements to avoid any interactions.
Amiloride (Midamor)
Amiloride can modestly reduce zinc excretion and increase zinc levels.
Clinical research shows that amiloride can reduce urinary zinc excretion, especially at doses of 10 mg per day or more. This zinc-sparing effect can help to counteract zinc losses caused by thiazide diuretics, but it is unlikely to cause zinc toxicity at usual amiloride doses. The other potassium-sparing diuretics, spironolactone (Aldactone) and triamterene (Dyrenium), do not seem to have a zinc-sparing effect.
Atazanavir (Reyataz)
Zinc modestly reduces levels of atazanavir, although this effect does not seem to be clinically significant.
Clinical research shows that zinc might decrease serum atazanavir levels by chelating with atazanavir in the gut and preventing its absorption. Although a single dose of zinc sulfate (Solvazinc tablets) 125 mg orally does not affect atazanavir concentrations in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate 125 mg daily for 2 weeks reduces plasma levels of atazanavir by about 22% in these patients. However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication.
Brand information
Manufacturer and brand details for Mojo, from the product label.
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Mojo’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Zinc
Interacts with 67 drugsZinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but supplements can help correct or prevent a defici...
Read the full Zinc monograph → Herb & supplement monographBoron
Boron is a trace mineral found in many plant foods and sold as a supplement, mainly promoted for bone, joint, and hormone health. The human evidence for most of these uses is limited or prel...
Read the full Boron monograph → Herb & supplement monographMagnesium
Interacts with 295 drugsMagnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preventing or correcting deficiency. Some othe...
Read the full Magnesium monograph → Herb & supplement monographColeus
Interacts with 915 drugsColeus is a plant from the mint family whose root contains a compound called forskolin, often marketed for weight loss, asthma, and heart health. While early lab and small human studies are...
Read the full Coleus monograph → Herb & supplement monographEurycoma Longifolia
Interacts with 248 drugsEurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....
Read the full Eurycoma Longifolia monograph →Sources & How We Checked
Mojo's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 196 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Zinc 88 references
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