Major interaction on record — check this product against your medications before combining. Based on 7 of 11 ingredients. Check your meds →
Dietary supplement

Muscle Matrix Protein Women's Formula Banana Ingredients & Drug Interactions

by NutraBio

Muscle Matrix Protein Women's Formula Banana label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Muscle Matrix Protein Women's Formula Banana against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Muscle Matrix Protein Women's Formula Banana is a dietary supplement by NutraBio with 11 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 2,099 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Xanthan Gum, Beta-Carotene, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Muscle Matrix Protein Women's Formula Banana by NutraBio

Ask about any prescription or over-the-counter medication and we check it for interactions with Muscle Matrix Protein Women's Formula Banana by NutraBio — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Muscle Matrix Protein Women's Formula Banana by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 10 of its 10 active ingredients.
  • “Flavoring” is listed as a grouped ingredient — the label gives one combined amount (797 mg) without saying how much of each component you get.

Muscle Matrix Protein Women's Formula Banana contains 10 ingredients total. The active protein components are whey protein isolate and micellar casein, which work together to provide muscle-supporting amino acids.

The formula also includes sodium, potassium, phosphorus, and calcium — minerals that support bone health and muscle function. Beta-carotene (a form of vitamin A) is added for antioxidant support.

Xanthan gum, a fiber, thickens the powder and may support digestion. The product uses sucralose (an artificial sweetener) and natural and other flavorings to achieve its banana taste.

There are no additional inactive ingredients listed beyond these.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: muscle growth and repair with sustained protein release.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, muscle protein synthesis, muscle recovery, muscle development.
  • The closest evidence on file: Calcium is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage (Natural Medicines).
  • Also on file: Whey Protein is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Exercise-induced muscle soreness, Exercise-induced muscle damage.
  • Also on file: Casein Protein is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Exercise-induced muscle soreness.

The effectiveness evidence varies by ingredient. Calcium in this formula is rated Likely Effective for osteoporosis and Effective for several other bone and digestive uses.

Whey protein is rated Possibly Effective for athletic performance but Possibly Ineffective for bone health. Xanthan gum shows Possibly Effective evidence for constipation and swallowing difficulty.

Beta-carotene is Effective for vitamin A deficiency and Possibly Effective for a range of other conditions including aging skin and measles. The product as a whole is marketed as a protein powder for women, but we hold effectiveness evidence only for its individual ingredients, not for the formulation as a complete product.

If you're considering this for a specific goal — whether muscle support, bone health, or athletic performance — talk with your doctor or pharmacist about how these individual ratings match your needs.

The evidence, ingredient by ingredient Sodium Potassium Calcium Xanthan Gum Vitamin A Whey Protein Casein Protein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The ingredients in this product are generally well tolerated at typical dietary amounts. However, sodium and potassium deserve caution: both are essential in normal amounts, but excess intake can raise blood pressure and stress the kidneys, especially in people with existing heart or kidney disease.

Calcium is generally safe at recommended amounts; very high doses raise theoretical concerns about prostate cancer and heart disease, though evidence is mixed. Beta-carotene is safe at recommended levels but can be toxic in very high doses, particularly in smokers and people with certain lung diseases.

Whey protein and casein (milk protein) are well tolerated by most people but can occasionally trigger acne or digestive side effects like bloating or diarrhea. People with milk allergies should avoid this product.

For pregnancy and breastfeeding, sodium is rated Likely Safe in normal amounts but Possibly Unsafe at high levels; potassium and calcium are both Likely Safe; and beta-carotene is Likely Safe at recommended amounts but Possibly Unsafe at high doses. There isn't enough data on file for whey, casein, xanthan gum, sucralose, or flavorings in pregnancy and breastfeeding — talk with your doctor or pharmacist for personalized guidance if you're pregnant or nursing.

Side effects, ingredient by ingredient Sodium Potassium Calcium Xanthan Gum Vitamin A Whey Protein Casein Protein

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 6 of the 7 matched ingredients can interact with medications — Xanthan Gum, Calcium, Whey Protein, Potassium, Vitamin A, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 2,100 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting this product, double-check the following medication types with your doctor or pharmacist: HIV integrase inhibitors (dolutegravir, elvitegravir) — calcium can significantly reduce their levels; blood pressure medications and lithium — sodium can interfere; potassium-sparing diuretics and blood pressure drugs like ACE inhibitors or ARBs — potassium may cause dangerous levels; thyroid medication (levothyroxine), certain antibiotics (quinolones, tetracyclines), and bisphosphonates — calcium can reduce absorption; and blood thinners like warfarin — beta-carotene at high doses may increase bleeding risk. No interactions are documented for the ingredients we could not check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a protein powder aimed at women, combining whey and casein proteins with added minerals and beta-carotene. It's generally well tolerated for healthy adults who don't have milk allergies and aren't taking medications that interact with calcium, potassium, sodium, or the other active ingredients.

If you take blood pressure medication, lithium, thyroid medication, antibiotics, bone medications, or any HIV treatment, check your specific drugs against the tool on this page before using it. Talk with your doctor or pharmacist about whether this product fits your individual health situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Muscle Matrix Protein Women's Formula Banana, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908256807
Net contents 1.5 lbs; 657 Gram(s)
Market status On market
Date entered into DSLD Oct 22, 2015
DSLD ID 51209
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Kosher, Adult Female (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Muscle Matrix Protein Women's Formula Banana by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
22 Gram(s)
Maximum serving Sizes:
22 Gram(s)
Servings per container
30
UPC/BARCODE
649908256807
IngredientAmount% DV
Calories80 {Calories}--
Total Carbohydrates1 Gram(s)1%
Protein18 Gram(s)36%
Sodium36 mg2%
Potassium85 mg2%
Cholesterol5 mg2%
Phosphorus121 mg12%
Calcium275 mg27%
Xanthan Gum300 mg--
Natural flavor417 mg--
Sucralose30 mg--
Beta-Carotene50 mg--
Flavoring797 mg--
Whey Protein isolate11.6 Gram(s)--
Micellar Casein9.5 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

1 serving 8 oz. shake well daily Suggested Use: Add 1 heaping scoop of Muscle Matrix with 6-8 ounces of cold water or beverage (milk, almond milk, rice milk, juice, etc.) and mix in a shaker cup. To make a creamy smoothie add 2-3 ice cubes and put in blender for 20-30 seconds. Vary the amount of liquid to meet your desired taste and consistency. Consume 1 scoop within 20 minutes after your workouts. Consume 1-3 servings daily as needed to satisfy your protein requirements.

Precautions

Do not use as a sole source of nutrition.

This product contains fractional amounts of sunflower oil and soy lecithin added during the instantization process. Allergens: Milk and soy (from lecithin).

Formula

PROVIDES UP TO 4 HOURS SUSTAINED RELEASE PROTEIN 55% Fast Release Whey Protein Isolate 45% Slow Release Micellar Casein Each serving Muscle Matrix contains 18 grams of pure, complete protein derived solely from 55% fast digesting Whey Protein Isolate and 45% slow digesting Micellar Casein.

HIGH CONCENTRATION OF BCAAs & AMINO ACIDS Shown is the typical amino acid profile per serving which is derived solely from whey protein isolate and micellar casein.

Alanine ............... 695 Arginine .............522 Aspartic Acid ...... 1536 Cysteine .............. 294 Glutamic Acid (Glutamine Precursor) ......3461 Glycine ................ 369 Histidine .............. 384 Isoleucine** ......... 1036 Leucine** ............. 1697 Lysine ................. 1620 Methionine ........... 418 Phenylalanine ..... 672 Proline ............... 1416 Serine ................ 857 Threonine .......... 995 Tryptophan ........... 258 Tyrosine ............. 753 Valine** ............... 1018 ** Branch Chain Amino Acids

Complete protein matrix

18 g Protein 80 Calories 3.75 g BCAAs

This product contains fractional amounts of sunflower oil and soy lecithin added during the instantization process. Allergens: Milk and soy (from lecithin).

Kosher

General Statements

This precise combination of proteins promotes positive nitrogen balance and elevates muscle protein synthesis for up to 4 continuous hours providing the perfect anabolic state for maximizing muscle growth and repair.

Quality and purity since 1996. NutraBio manufactures in our own FDA registered & inspected GMP facility complying with FDA 21 CFR Part 111 regulations.

Manufactured in a GMP & FDA inspected facility FDA Registration: 16906175560

HIGH PROTEIN ~ LOW CALORIE

MAXIMIZE Protein Synthesis BUILD & Repair Muscle 4-HOUR Sustained Release

Made in a GMP & FDA inspected facility

This product is intended as a dietary supplement only. Do not use as a sole source of nutrition.

Serving scoop included, but may settle to the bottom during shipping.

Since 1996

Made in USA

Full label disclosure No proprietary blends Every ingredient disclosed with dosage

Powder 30 servings

Formulation

NO WHEY CONCENTRATE NO ION EXCHANGE WHEY NO PROPRIETARY BLENDS NO HIDDEN INGREDIENTS NO BANNED SUBSTANCES NO DEXTROSE/MALTODEXTRIN NO FILLERS, EXCIPIENTS or CREAMERS NO FAT or SUGAR

Absolutely no amino acids or other ingredients have been added to spike protein values.

Gluten Free ~ BSE/TSE Free

Seals/Symbols

NO AMINO SPIKING SPIKE FREE

TRUE LABEL FULL LABEL DISCLOSURE

OU D

FDA Statement of Identity

Dietary Supplement

Storage

STORE IN A COOL DRY PLACE.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

25680-000 B20558-000

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Muscle Matrix Protein Women's Formula Banana by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Muscle Matrix Protein Women's Formula Banana label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Muscle Matrix Protein Women's Formula Banana by NutraBio

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size22 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

18 Gram(s) per serving

Sodium

Interacts with
205 drugs
36 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs
85 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Phosphorus

121 mg per serving

Calcium

Interacts with
168 drugs
275 mg per serving

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Flavoring

797 mg per serving

Whey Protein isolate

Interacts with
53 drugs
11.6 Gram(s) per serving

Whey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined...

Whey Protein isolate monograph & interactions

Micellar Casein

No known
interactions
9.5 Gram(s) per serving

Casein is a slow-digesting protein from milk that supplies all the essential amino acids and is popular for muscle recovery, especially overnight. It...

Micellar Casein monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Muscle Matrix Protein Women's Formula Banana by NutraBio Drug Interactions

Want to check YOUR meds against Muscle Matrix Protein Women's Formula Banana?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,099Drugs
21 Major 620 Moderate 1,458 Minor

Ingredients driving the most interactions

Xanthan Gum 2,022
Beta-Carotene 389
Sodium 205
Calcium 168
Potassium 62

Individual Drug Interactions

The ingredients in Muscle Matrix Protein Women's Formula Banana interact with 2,099 drugs. Click any drug to see the details.

6 of the 11 ingredients in Muscle Matrix Protein Women's Formula Banana interact with drugs. Each result below shows which ingredient is responsible. Xanthan Gum Beta-Carotene Sodium Calcium Potassium Whey Protein isolate

Each ingredient & the kinds of drugs it affects

For each ingredient in Muscle Matrix Protein Women's Formula Banana with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Xanthan Gum1 drug type · 2,022 drugs

Oral Drugs

Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities. Xanthan gum slows gastric emptying and has been used to control the release of drugs in tablet formulations. To avoid any alterations in drug absorption, xanthan gum should be taken 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Xanthan Gum full monograph & interactions

Beta-Carotene4 drug types · 389 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
Beta-Carotene full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions

Whey Protein isolate4 drug types · 53 drugs

Levodopa

Theoretically, whey protein might decrease levodopa absorption.
Small clinical studies show that concomitant ingestion of protein or high doses of leucine or isoleucine (100 mg/kg) and levodopa can exacerbate tremor, rigidity, and the "on-off" syndrome in patients with Parkinson disease.

Likelihood Probable Evidence D
Bisphosphonates

Theoretically, whey protein might reduce the absorption of bisphosphonates.
Whey protein contains minerals such as calcium that bind bisphosphonates in the gut. Advise patients to take bisphosphonates at least 30 minutes before whey protein, but preferably at a different time of day.

Likelihood Probable Evidence D
Quinolone Antibiotics

Theoretically, whey protein might decrease quinolone absorption.
Whey protein contains minerals, such as calcium, that can bind to quinolones in the gut. To avoid this interaction, advise patients to take oral quinolones at least 2 hours before or 4-6 hours after whey protein.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, whey protein might decrease tetracycline absorption.
Whey protein contains minerals, such as calcium, that bind to tetracyclines in the gut. To avoid this interaction, advise patients to take oral tetracyclines at least 2 hours before or 4-6 hours after whey protein.

Likelihood Probable Evidence D
Whey Protein isolate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Muscle Matrix Protein Women's Formula Banana, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

Muscle Matrix Protein Women's Formula Banana by NutraBio: Common Questions

Does Muscle Matrix Protein Women's Formula Banana by NutraBio interact with any medications?
Yes. Based on its ingredients, Muscle Matrix Protein Women's Formula Banana has a known interaction with 2,099 medications, including 21 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Muscle Matrix Protein Women's Formula Banana contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to use if I'm pregnant or breastfeeding?
Sodium and potassium are Likely Safe at normal dietary amounts during pregnancy and breastfeeding; calcium is Likely Safe at recommended amounts; and beta-carotene is Likely Safe at recommended doses but Possibly Unsafe at high levels. We don't have pregnancy or breastfeeding data for the whey, casein, sucralose, xanthan gum, and flavorings. Talk with your doctor or pharmacist for personalized advice, especially if you're considering this as a supplement rather than food.
Can whey protein cause acne?
Yes — multiple case reports link whey protein supplements to the onset or worsening of acne in teenagers and young adults, typically a dose-related effect. Acne usually cleared when people stopped using whey protein. If you're prone to acne, mention this to your doctor before using a high-protein powder.
What does beta-carotene in this product do?
Beta-carotene is a form of vitamin A that acts as an antioxidant. The evidence shows it's Effective for vitamin A deficiency and Possibly Effective for aging skin, measles, and other conditions. At the amount in a protein powder, it's generally safe, but very high doses can be toxic — especially in smokers.
Will this help me build muscle?
The product contains whey and casein protein, both of which provide amino acids for muscle support. Whey protein specifically is rated Possibly Effective for athletic performance. Individual results depend on your training, overall diet, and other factors — talk with your doctor or trainer about whether this fits your fitness goals.
Is this okay if I have high blood pressure or take blood pressure medication?
This product contains sodium, which can reduce the effectiveness of blood pressure medications, and potassium, which may increase risks when combined with certain blood pressure drugs. If you have high blood pressure or take any blood pressure medication, check your specific drugs using the tool on this page, and talk with your doctor or pharmacist before using it.
Can I take this with my thyroid medication?
The calcium in this product can reduce the absorption of thyroid medication like levothyroxine, making it less effective. If you take a thyroid drug, separate this powder from your medication by at least 4 hours, and confirm the specifics with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Muscle Matrix Protein Women's Formula Banana label
Go deeper

The Full Monographs Behind Muscle Matrix Protein Women's Formula Banana’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Xanthan Gum

Interacts with 2,022 drugs

Xanthan gum is a fermentation-made fiber widely used to thicken and stabilize foods and to thicken liquids for people with swallowing difficulties. It is generally recognized as safe in the...

Read the full Xanthan Gum monograph → Herb & supplement monograph

Vitamin A

Interacts with 389 drugs

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a tr...

Read the full Vitamin A monograph → Herb & supplement monograph

Whey Protein

Interacts with 53 drugs

Whey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined with exercise. It is generally safe for...

Read the full Whey Protein monograph → Herb & supplement monograph

Casein Protein

Casein is a slow-digesting protein from milk that supplies all the essential amino acids and is popular for muscle recovery, especially overnight. It is generally safe for most people who to...

Read the full Casein Protein monograph →
Sources

Sources & How We Checked

Muscle Matrix Protein Women's Formula Banana's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 239 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
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  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
  18. Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
  19. O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
  20. Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
  21. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
  22. Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
  23. Yancy CW. Sodium Restriction in Heart Failure: Too Much Uncertainty-Do the Trials. JAMA Intern Med. 2018 Dec 1;178(12):1700-1701. PubMed
  24. He FJ, Campbell NRC, Ma Y, MacGregor GA, Cogswell ME, Cook NR. Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health. Int J Epidemiol. 2018;47(6):1784-1795. PubMed
  25. Murthy K, Ondrey GJ, Malkani N, et al. THE EFFECTS OF HYPONATREMIA ON BONE DENSITY AND FRACTURES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Endocr Pract. 2019;25(4):366-378. PubMed
  26. Messerli FH, Hofstetter L, Syrogiannouli L, et al. Sodium intake, life expectancy, and all-cause mortality. Eur Heart J 2021;42(21):2103-2112. PubMed
  27. Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev 2020;12(12):CD004022. PubMed
  28. Giatti S, Santos RB, Aielo AN, et al. Association of sodium with obstructive sleep apnea. The ELSA-Brasil study. Ann Am Thorac Soc 2021;18(3):502-510. PubMed
  29. Nan X, Lu H, Wu J, et al. The interactive association between sodium intake, alcohol consumption and hypertension among elderly in northern China: a cross-sectional study. BMC Geriatr 2021;21(1):135. PubMed
  30. Kyozuka H, Fukusda T, Murata T, et al. Impact of preconception sodium intake on hypertensive disorders of pregnancy: The Japan Environment and Children's study. Pregnancy Hypertens 2021;23:66-72. PubMed
  31. Zhao L, Ogden CL, Yang Q, et al. Association of usual sodium intake with obesity among US children and adolescents, NHANES 2009-2016. Obesity (Silver Spring) 2021;29(3):587-594. PubMed
  32. Ma Y, He FJ, Sun Q, et al. 24-Hour urinary sodium and potassium excretion and cardiovascular risk. N Engl J Med 2022;386(3):252-263. PubMed
  33. Liu J, Yang X, Zhang P, et al. Association of urinary sodium excretion and left ventricular hypertrophy in people with type 2 diabetes mellitus: A cross-sectional study. Front Endocrinol (Lausanne) 2021;12:728493. PubMed
  34. Filippini T, Malavolti M, Whelton PK, Vinceti M. Sodium intake and risk of hypertension: A systematic review and dose-response meta-analysis of observational cohort studies. Curr Hypertens Rep 2022;24(5):133-144. PubMed
  35. Wang DD, Li Y, Nguyen XT, et al. Dietary sodium and potassium intake and risk of non-fatal cardiovascular diseases: The million veteran program. Nutrients 2022;14(5):1121. PubMed
  36. Kwak JH, Park CH, Eun CS, et al. The associations of dietary intake of high sodium and low zinc with gastric cancer mortality: A prospective cohort study in Korea. Nutr Cancer 2022;74(10):3501-3508. PubMed
  37. George S, Maiti R, Mishra BR, Jena M, Mohapatra D. Effect of regulated add-on sodium chloride intake on stabilization of serum lithium concentration in bipolar disorder: A randomized controlled trial. Bipolar Disord 2023;25(1):66-75. PubMed
  38. Zhou TL, Schütten MTJ, Kroon AA, et al. Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population. J Am Heart Assoc 2023;12(1):e026578. PubMed

See these in context on the Sodium monograph →

Potassium 12 references
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  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
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  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Calcium 62 references
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See these in context on the Calcium monograph →

Xanthan Gum 11 references
  1. Sargent EV, Adolph J, Clemmons MK, et al. Evaluation of flu-like symptoms in workers handling xanthan gum powder. Occup Med 1990;32:625-30. PubMed
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