Mushroom Master Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Mushroom Master against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Mushroom Master is a dietary supplement by Tonic Tinctures with 11 active ingredients. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 658 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi extract, Chaga extract, Lion's Mane extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Mushroom Master by Tonic Tinctures
Ask about any prescription or over-the-counter medication and we check it for interactions with Mushroom Master by Tonic Tinctures — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Mushroom Master by Tonic Tinctures
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Mushroom Master contains 11 active ingredients, all mushroom extracts: reishi, chaga, cordyceps, mesima (black hoof mushroom), lion's mane, turkey tail, maitake, agarikon, suehirotake, oyster mushroom, and true tinder conk polypore. These are blended with distilled water and organic alcohol as inactive ingredients.
Each extract brings its own compounds — polysaccharides, beta-glucans, and other bioactive molecules — though how much of each is in this liquid formula isn't specified on the label.
Does it work?
Couldn't assess
The evidence for most of these mushrooms is still being built. For reishi, the data suggests it's possibly ineffective for high cholesterol.
For chaga, cordyceps, mesima, lion's mane, and maitake, the conditions they're studied for — including diabetes, heart disease, cognitive function, athletic performance, and immune support — all carry a rating of insufficient reliable evidence to rate their effectiveness. In other words, we don't yet have solid clinical proof that this product works for any particular condition.
How safe is it?
Well-documented data
Reishi, chaga, cordyceps, lion's mane, and maitake are generally well tolerated in the short term, but long-term safety data are limited or lacking. The most common side effects across these mushrooms are gastrointestinal (nausea, diarrhea, abdominal discomfort, stomach upset), along with dizziness, dry mouth, itching, and rash in some people.
Chaga has been linked to kidney problems with very high intake due to its oxalate content, and cordyceps has one rare case report of liver inflammation, though it's unclear whether cordyceps was the cause. We hold no safety data for turkey tail, agarikon, suehirotake, oyster mushroom, or true tinder conk polypore.
Because the safety data for all ingredients in pregnancy and breastfeeding are not sufficient, these are best avoided during both periods — talk with your doctor or pharmacist about whether it's right for you.
Meds to double-check
Moderate interaction found
Before taking Mushroom Master, check with your doctor or pharmacist if you take any blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel), blood pressure medications, diabetes medications, immune-suppressing drugs, or any medication processed by your liver via the CYP1A2 or CYP2E1 pathways. Additionally, if you take testosterone, mention this product since cordyceps may have additive effects.
No interactions are documented for turkey tail, agarikon, suehirotake, oyster mushroom, or true tinder conk polypore in our data, but that's because we hold no data for those ingredients at all.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Mushroom Master is a multi-extract blend aimed at general wellness, but the evidence for what it actually does is not yet established. If you take blood thinners, blood pressure medication, diabetes medication, or immunosuppressants, you'll need to clear this product with your doctor or pharmacist first — the mushroom extracts here have documented or theoretical interactions with each of those categories.
If you're pregnant or breastfeeding, the data aren't there to say it's safe. Talk it over with your own healthcare provider before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Mushroom Master, straight from the product label.
| Brand | Tonic Tinctures |
|---|---|
| Net contents | 2 fl. Oz.; 60 mL |
| Market status | On market |
| Date entered into DSLD | Dec 26, 2020 |
| DSLD ID | 241242 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Mushroom Master by Tonic Tinctures, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Reishi extract | 0 NP | -- |
| Chaga extract | 0 NP | -- |
| Cordyceps extract | 0 NP | -- |
| Mesima extract | 0 NP | -- |
| Lion's Mane extract | 0 NP | -- |
| Turkey Tail extract | 0 NP | -- |
| Maitake extract | 0 NP | -- |
| Agarikon extract | 0 NP | -- |
| Suehirotake extract | 0 NP | -- |
| Oyster Mushroom extract | 0 NP | -- |
| True Tinder Conk Polypore extraction | 0 NP | -- |
Other ingredients: distilled Water, organic Alcohol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Artisan liquid extract 1 dropper is approximately equal to 1250 mgs
Gluten free, no hidden additives
Suggested/Recommended/Usage/Directions
Shake gently before use
Directions: Use as directed, 1-3 droppers 1-3 times a day. Use within 45 days of opening.
Precautions
Keep out of reach of children.
Discontinue use if unusual symptoms occur.
FDA Disclaimer Statement
Caution: These products are not intended to diagnose, treat, cure or prevent any disease. These statements have not been evaluated by the FDA
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Mushroom Master by Tonic Tinctures label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Mushroom Master by Tonic Tinctures
These are the 11 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Dropper(s) Dosage formLiquid Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Reishi extract
Interacts with375 drugs
Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...
Reishi extract monograph & interactionsChaga extract
Interacts with327 drugs
Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for i...
Chaga extract monograph & interactionsCordyceps extract
Interacts with249 drugs
Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...
Cordyceps extract monograph & interactionsMesima extract
Interacts with308 drugs
Black Hoof Mushroom (Phellinus linteus) is a medicinal mushroom long used in East Asian traditional medicine, mainly for immune support. Most of the s...
Mesima extract monograph & interactionsLion's Mane extract
Interacts with327 drugs
Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...
Lion's Mane extract monograph & interactionsTurkey Tail extract
Maitake extract
Interacts with260 drugs
Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and bl...
Maitake extract monograph & interactionsAgarikon extract
Suehirotake extract
Oyster Mushroom extract
True Tinder Conk Polypore extraction
Other (inactive) ingredients: Distilled Water, Organic Alcohol. These complete the product’s ingredient list but are not active constituents.
Mushroom Master by Tonic Tinctures Drug Interactions
HelloPharmacist Interaction Report
Mushroom Master by Tonic Tinctures contains multiple mushroom extracts that interact with several medication categories.
Through its reishi, chaga, cordyceps, mesima, lion's mane, and maitake content, the most serious interaction is a Moderate risk of elevated bleeding when combined with blood thinners (anticoagulant/antiplatelet drugs) — chaga, cordyceps, lion's mane, and reishi all carry this concern, and maitake has a documented case report showing it may boost warfarin's anticoagulant effects.
Read the full breakdown — every affected drug type, severity by severity
The remaining major concern is blood pressure medication: reishi and maitake both may lower blood pressure further when used alongside antihypertensive drugs. Reishi, chaga, lion's mane, and maitake all theoretically increase the risk of low blood sugar (hypoglycemia) when combined with diabetes medications, though clinical evidence is mixed.
Cordyceps and lion's mane may interfere with immune-suppressing medications, and mesima may alter levels of certain drugs broken down by your liver (specifically those processed by CYP1A2 and CYP2E1 enzymes). Cordyceps also carries a Minor interaction with testosterone products.
We could not check the interaction data for turkey tail, agarikon, suehirotake, oyster mushroom, or true tinder conk polypore. Altogether, these interactions span 658 individual medications.
Use the medication checker below to see whether any of your specific drugs are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Mushroom Master?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Mushroom Master interact with 658 drugs. Click any drug to see the details.
6 of the 11 ingredients in Mushroom Master interact with drugs. Each result below shows which ingredient is responsible. Reishi extract Chaga extract Lion's Mane extract Mesima extract Maitake extract Cordyceps extract
Conjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Mushroom Master — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps ExtractTestosterone Minor
Interaction Summary
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Read the full Cordyceps Extract + Conjugated Estrogens, Methyltestosterone interactionDiethylstilbestrol, MethyltestosteroneTylosterone
How Diethylstilbestrol, Methyltestosterone interacts with Mushroom Master — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps ExtractTestosterone Minor
Interaction Summary
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Read the full Cordyceps Extract + Diethylstilbestrol, Methyltestosterone interactionEsterified Estrogens, MethyltestosteroneEstratest
How Esterified Estrogens, Methyltestosterone interacts with Mushroom Master — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps ExtractTestosterone Minor
Interaction Summary
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Read the full Cordyceps Extract + Esterified Estrogens, Methyltestosterone interactionMethyltestosteroneAndroid 10, Android 25, Metandren, Methitest, Oreton, Testred +1 more
How Methyltestosterone interacts with Mushroom Master — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps ExtractTestosterone Minor
Interaction Summary
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Read the full Cordyceps Extract + Methyltestosterone interactionMethyltestosterone BuccalAndroid 5, Oreton Buccal
How Methyltestosterone Buccal interacts with Mushroom Master — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps ExtractTestosterone Minor
Interaction Summary
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Read the full Cordyceps Extract + Methyltestosterone Buccal interactionTestosteroneAndrogel, Andropatch, Delatestryl, Intrinsa, Natesto, Nebido +3 more
How Testosterone interacts with Mushroom Master — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps ExtractTestosterone Minor
Interaction Summary
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Read the full Cordyceps Extract + Testosterone interactionTestosterone EnanthateXyosted
How Testosterone Enanthate interacts with Mushroom Master — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps ExtractTestosterone Minor
Interaction Summary
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Read the full Cordyceps Extract + Testosterone Enanthate interactionTestosterone UndecanoateAndriol, Aveed, Jatenzo, Kyzatrex
How Testosterone Undecanoate interacts with Mushroom Master — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps ExtractTestosterone Minor
Interaction Summary
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Read the full Cordyceps Extract + Testosterone Undecanoate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Mushroom Master with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Reishi extract
Anticoagulant/Antiplatelet Drugs
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.
Antidiabetes Drugs
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.
Antihypertensive Drugs
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.
Chaga extract
Anticoagulant/Antiplatelet Drugs
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.
Antidiabetes Drugs
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.
Immunosuppressants
Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.
Lion's Mane extract
Anticoagulant/Antiplatelet Drugs
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.
Antidiabetes Drugs
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.
Immunosuppressants
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.
Mesima extract
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, black hoof mushroom might increase the levels and clinical effects of CYP1A2 substrates.
In vitro, polysaccharides from black hoof mushroom grown in culture inhibit CYP1A2. This effect has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, black hoof mushroom might increase the levels and clinical effects of CYP2E1 substrates.
In vitro, polysaccharides from black hoof mushroom grown in culture inhibit CYP2E1. This effect has not been reported in humans.
Immunosuppressants
Theoretically, black hoof mushroom might reduce the effects of immunosuppressant medications.
In animal research, polysaccharides from black hoof mushroom and black hoof mushroom extract stimulate immune responses.
Maitake extract
Antidiabetes Drugs
Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.
Antihypertensive Drugs
Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.
Warfarin (Coumadin)
There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.
Cordyceps extract
Anticoagulant/Antiplatelet Drugs
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.
Immunosuppressants
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.
Testosterone
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.
Brand information
Manufacturer and brand details for Mushroom Master, from the product label.
Tonic Tinctures
See all Tonic Tinctures products- Name
- Tonic Apothecary
- Web Address
- www.tonictinctures.com
Mushroom Master by Tonic Tinctures: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Mushroom Master’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Reishi Mushroom
Interacts with 375 drugsReishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...
Read the full Reishi Mushroom monograph → Herb & supplement monographChaga
Interacts with 327 drugsChaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...
Read the full Chaga monograph → Herb & supplement monographCordyceps
Interacts with 249 drugsCordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...
Read the full Cordyceps monograph → Herb & supplement monographBlack Hoof Mushroom
Interacts with 308 drugsBlack Hoof Mushroom (Phellinus linteus) is a medicinal mushroom long used in East Asian traditional medicine, mainly for immune support. Most of the supporting evidence comes from laboratory...
Read the full Black Hoof Mushroom monograph → Herb & supplement monographLion's Mane Mushroom
Interacts with 327 drugsLion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...
Read the full Lion's Mane Mushroom monograph → Herb & supplement monographMaitake Mushroom
Interacts with 260 drugsMaitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...
Read the full Maitake Mushroom monograph →Sources & How We Checked
Mushroom Master's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 60 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Reishi Mushroom 17 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
- Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
- Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
- Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
- Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
- Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
- Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
- Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
- Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
- Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
- Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
- Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
- Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
- Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
- Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
- Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.
Chaga 9 references
- Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
- Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
- Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
- Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
- Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
- Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
- Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
- Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
- Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed
Cordyceps 14 references
- Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
- Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
- Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
- Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
- Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
- Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
- Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
- Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
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- Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
- Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
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Black Hoof Mushroom 6 references
- Song, K. S., Cho, S. M., Lee, J. H., Kim, H. M., Han, S. B., Ko, K. S., and Yoo, I. D. B-lymphocyte-stimulating polysaccharide from mushroom Phellinus linteus. Chem Pharm Bull (Tokyo) 1995;43(12):2105-2108. PubMed
- Matsuba, S., Matsuno, H., Sakuma, M., and Komatsu, Y. Phellinus linteus Extract Augments the Immune Response in Mitomycin C-Induced Immunodeficient Mice. Evid Based Complement Alternat Med 2008;5(1):85-90.
- Kim, G. Y., Roh, S. I., Park, S. K., Ahn, S. C., Oh, Y. H., Lee, J. D., and Park, Y. M. Alleviation of experimental septic shock in mice by acidic polysaccharide isolated from the medicinal mushroom Phellinus linteus. Biol Pharm Bull 2003;26(10):1418-1423 PubMed
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Lion's Mane Mushroom 6 references
- Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
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See these in context on the Lion's Mane Mushroom monograph →
Maitake Mushroom 8 references
- Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol (Tokyo) 1989;35:91-4. PubMed
- Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo) 1987;33:341-6. PubMed
- Konno S, Tortorelis DG, Fullerton SA, et al. A possible hypoglycaemic effect of maitake mushroom on Type 2 diabetic patients. Diabet Med 2001;18:1010. PubMed
- Chen JT, Tominaga K, Sato Y, et al. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. J Altern Compl
- Hanselin MR, Vande Griend JP, Linnebur SA. INR elevation with maitake extract in combination with warfarin. Ann Pharmacother 2010;44:223-4. PubMed
- Talpur, N. A., Echard, B. W., Fan, A. Y., Jaffari, O., Bagchi, D., and Preuss, H. G. Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains. Mol.Cell Biochem. 2002;237(1-2):129-136. PubMed
- Deng, G., Lin, H., Seidman, A., Fornier, M., D'Andrea, G., Wesa, K., Yeung, S., Cunningham-Rundles, S., Vickers, A. J., and Cassileth, B. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: i
- Wesa KM, Cunningham-Rundles S, Klimek VM, et al. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 2015;64(2):237-47. PubMed
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