Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Chaga Ingredients & Drug Interactions

by Tonic Tinctures

Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Chaga is a dietary supplement by Tonic Tinctures with 2 active ingredients. Its ingredients are commonly taken for immune support, antioxidant support, general wellness/tonic.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic USA hardwood Chaga extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Chaga by Tonic Tinctures

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.

This tincture contains two Chaga extracts — one from organic USA hardwood and one from wildcrafted North American sources — making up the 2 active ingredients. Chaga is a fungal growth that appears on birch trees; these extracts are meant to deliver its compounds in liquid form.

The product also contains distilled water and organic alcohol as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Chaga product and its label doesn't state a use — see Chaga's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for chaga isn't established yet. For cardiovascular disease, diabetes, and COVID-19, the data we hold shows insufficient reliable evidence to rate how well it works.

If you're considering it for any of these conditions, that's a conversation to have with your doctor — we can't say chaga will or won't help based on what's currently documented.

The evidence, ingredient by ingredient Chaga

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chaga is generally used in foods and teas, but human safety data are limited and some risks have been reported. There have been cases of kidney damage — two cases of kidney failure and one of acute nephropathy — linked to very high chaga consumption; chaga contains high concentrations of oxalate, which can be hard on the kidneys if you consume excessive amounts.

The safety data advises against using chaga during pregnancy and while breastfeeding because there isn't enough information to know it's safe.

Side effects, ingredient by ingredient Chaga

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chaga.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Chaga by Tonic Tinctures, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs like warfarin or aspirin (Moderate risk of increased bleeding). Also confirm if you take immunosuppressants or antidiabetes medications, since chaga may theoretically interfere with how they work or raise your low-blood-sugar risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Chaga may appeal to you if you're interested in traditional or herbal supplements, but the evidence for what it actually does isn't established yet. Be especially cautious if you take blood thinners, medications that suppress your immune system, or diabetes drugs — check with your doctor or pharmacist before adding this.

Skip it if you're pregnant or breastfeeding, and talk with your healthcare provider if you have kidney concerns or take any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chaga, straight from the product label.

Brand Tonic Tinctures
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 241177
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chaga by Tonic Tinctures, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Dropper(s)
Maximum serving Sizes:
3 Dropper(s)
Servings per container
60
IngredientAmount% DV
organic USA hardwood Chaga extract0 NP--
wildcrafted North American Chaga extract0 NP--

Other ingredients: distilled Water, organic Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Artisan liquid extract 1 dropper is approximately equal to 1000 mgs

Formulation

Gluten free, no hidden additives

Suggested/Recommended/Usage/Directions

Shake gently before use

Directions: Use as directed, 1-3 droppers 1-3 times a day. Use within 45 days of opening.

Precautions

Keep out of reach of children.

Discontinue use if unusual symptoms occur.

FDA Disclaimer Statement

Caution: These products are not intended to diagnose, treat, cure or prevent any disease. These statements have not been evaluated by the FDA

FDA Statement of Identity

Dietary Supplement

See for yourself

Chaga by Tonic Tinctures label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Chaga by Tonic Tinctures

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Dropper(s) Dosage formLiquid Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic USA hardwood Chaga extract

Interacts with
327 drugs
0 NP per serving

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for i...

Organic USA hardwood Chaga extract monograph & interactions
0 NP per serving

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for i...

Wildcrafted North American Chaga extract monograph & interactions

Other (inactive) ingredients: Distilled Water, Organic Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chaga by Tonic Tinctures Drug Interactions

Want to check YOUR meds against Chaga?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Chaga with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic USA hardwood Chaga extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Chaga, from the product label.

Tonic Tinctures

See all Tonic Tinctures products
Name
Tonic Apothecary
Web Address
www.tonictinctures.com
Pharmacist Counseling Corner

Chaga by Tonic Tinctures: Common Questions

Does Chaga by Tonic Tinctures interact with any medications?
Yes. Based on its ingredients, Chaga has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chaga contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against it — there isn't enough information to know whether chaga is safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you.
Does chaga actually work for heart health or blood sugar?
The evidence isn't established yet. For cardiovascular disease and diabetes, we don't have enough reliable data to say how well it works. That's something to discuss with your doctor if you're thinking about using it for those purposes.
What are the side effects I should know about?
The main concern is kidney damage from very high intake — there have been cases of kidney failure and kidney inflammation linked to excessive chaga consumption because it's high in oxalate. Human safety data overall are limited, so if you have kidney concerns, talk with your pharmacist or doctor first.
What exactly is chaga?
Chaga is a fungal growth that appears on birch trees. This product extracts its compounds into a liquid form with water and alcohol as carriers.
Is this product safe to use with my medications?
That depends on what you take. Chaga interacts with blood thinners, immunosuppressants, and diabetes drugs — check your exact prescriptions with the tool on this page, and confirm with your doctor or pharmacist before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chaga is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chaga label
Sources

Sources & How We Checked

Chaga's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chaga 9 references
  1. Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
  2. Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
  3. Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
  4. Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
  5. Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
  6. Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
  7. Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
  8. Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
  9. Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed

See these in context on the Chaga monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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