Interactions on record — worth a quick check against your medications. Based on 6 of 7 ingredients. Check your meds →
Dietary supplement

Mycotaki Ingredients & Drug Interactions

by Metagenics

Mycotaki label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mycotaki against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Mycotaki is a dietary supplement by Metagenics with 7 active ingredients. Its ingredients are commonly taken for fluid retention and swelling, digestive complaints, sleep and calming support.Based on those ingredients, 997 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Poria cocos Sclerotium Extract, Reishi fruiting body extract, Shiitake Fruiting Body Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Mycotaki by Metagenics

Ask about any prescription or over-the-counter medication and we check it for interactions with Mycotaki by Metagenics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Mycotaki by Metagenics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,300 mg) without saying how much of each component you get.

Mycotaki contains seven active ingredients: a proprietary blend that includes poria cocos sclerotium extract, reishi fruiting body extract, shiitake fruiting body extract, oyster mushroom fruiting body extract, maitake fruiting body extract, turkey tail mushroom fruiting body extract, and cordyceps mycelia extract. These are all mushroom-derived ingredients intended to support immune and metabolic function.

The product also contains inactive ingredients—microcrystalline cellulose, cellulose, stearic acid, croscarmellose sodium, silica, hypromellose, medium chain triglyceride, and hydroxypropyl cellulose—which serve as binders, fillers, and capsule materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support cellular defenses and healthy immune system.
  • We looked for evidence on: Allergic rhinitis (hay fever), Asthma, Bronchitis, Cancer, Cancer-related fatigue, Chemotherapy-induced anemia — and 4 related terms.
  • The strongest evidence on file: Turkey Tail Mushroom is rated "Possibly Effective" for Cancer (Natural Medicines).
  • Also on file: Poria Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cancer.
  • Also on file: Maitake Mushroom is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever), Chemotherapy-induced anemia, Laryngeal cancer, Chemotherapy-related fatigue, and more.

The evidence for most of Mycotaki's ingredients remains inconclusive. Poria, reishi, shiitake, maitake, and cordyceps have insufficient reliable evidence to rate their effectiveness for conditions like diabetes, chronic fatigue, cancer, and respiratory health.

Turkey tail mushroom is the exception—it is rated possibly effective for cancer, though the strength of that evidence is limited. Reishi is rated possibly ineffective for high cholesterol.

Overall, the science supporting these mushroom extracts for the conditions they're marketed for is not yet well established in the data we hold.

The evidence, ingredient by ingredient Poria Mushroom Reishi Mushroom Shiitake Mushroom Maitake Mushroom Turkey Tail Mushroom Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these mushroom extracts are generally well tolerated short-term when used as directed. Reishi, maitake, and cordyceps show the most clinical experience, though long-term safety data are limited for all of them.

Common mild side effects include gastrointestinal upset (nausea, diarrhea, stomach discomfort, diarrhea), dizziness, dry mouth, rash, and itching. Shiitake can cause skin reactions, especially if consumed raw or if you handle the mushroom directly; allergic reactions including asthma and respiratory issues have been reported.

Poria and reishi rarely trigger allergic reactions. Cordyceps carry a single case report of liver inflammation, though causation is uncertain.

For pregnancy and breastfeeding, the safety data for all six mushroom extracts we could check are insufficient. The facts advise against poria, reishi, shiitake, maitake, turkey tail, and cordyceps during pregnancy and breastfeeding.

Talk with your doctor or pharmacist about whether this product is appropriate for you if you are pregnant, may become pregnant, or are breastfeeding.

Side effects, ingredient by ingredient Poria Mushroom Reishi Mushroom Shiitake Mushroom Maitake Mushroom Turkey Tail Mushroom Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Poria Mushroom, Maitake Mushroom, Cordyceps, Turkey Tail Mushroom, Shiitake Mushroom, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 997 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Mycotaki, check with your doctor or pharmacist if you take warfarin or other blood thinners and antiplatelet drugs (moderate risk of increased bleeding), blood pressure medications (moderate risk of excessively low blood pressure), diabetes drugs (moderate risk of excessively low blood sugar), or immune-suppressants like cyclosporine (moderate risk of reduced effectiveness). Additionally, if you take tamoxifen, cyclophosphamide, sedatives, anticholinergic or cholinergic drugs, or any medication metabolized by the CYP2D6 or CYP2C9 liver enzymes, discuss this product with your healthcare provider before starting it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Mycotaki is a mushroom-extract blend with limited evidence for most of its claimed benefits and significant documented interactions with blood thinners, blood pressure drugs, diabetes medications, and several other medication types. If you take warfarin, antihypertensive drugs, diabetes medications, or any immune-suppressant therapy, check with your doctor or pharmacist before using this product.

Even if you don't take those medications, run your full prescription list through the search tool on this page to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mycotaki, straight from the product label.

Brand Metagenics
Barcode (UPC) 755571915153
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 295804
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mycotaki by Metagenics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
45
UPC/BARCODE
755571915153
IngredientAmount% DV
Proprietary Blend1300 mg--
Poria cocos Sclerotium Extract0 NP--
Reishi fruiting body extract0 NP--
Shiitake Fruiting Body Extract0 NP--
Oyster Mushroom Fruiting Body Extract0 NP--
Maitake Fruiting Body Extract0 NP--
Turkey Tail Mushroom Fruiting Body Extract0 NP--
Cordyceps Mycelia Extract0 NP--

Other ingredients: Microcrystalline Cellulose, Cellulose, Stearic Acid, Croscarmellose Sodium, Silica, Hypromellose, Medium Chain Triglyceride, Hydroxypropyl Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Mycotaki features a concentrated water extract of 7 nourishing mushrooms with an extensive history of use in supporting human health. This powerful formula helps to support cellular defenses and a healthy immune system, which are critical for maintaining vitality and overall well-being. Ideal for those seeking additional immune support during occasional physical or emotional stress.

Equivalent to 13 g raw, dried, unprocessed mushrooms. An asexual derivation of Cordyceps sinensis reported by the Institute of Microbiology, the Chinese Academy Sciences, Beijing, PRC.

Suggested/Recommended/Usage/Directions

Directions: Take two tablets daily or as directed by your healthcare practitioner.

Formulation

This product is non-GMO, gluten-free and vegetarian.

This product is non-GMO, gluten-free and vegetarian.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Supports an immune system under occasional stress

Precautions

Warning: Do not use if pregnant or nursing. Caution: If taking medication, including anticoagulants or antihypertensive medications, consult your healthcare practitioner before use.

Keep out of reach of children.

Practitioner Exclusive

Storage

Do not refrigerate.

Seals/Symbols

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mycotaki by Metagenics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mycotaki label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mycotaki by Metagenics

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Microcrystalline Cellulose, Cellulose, Stearic Acid, Croscarmellose Sodium, Silica, Hypromellose, Medium Chain Triglyceride, Hydroxypropyl Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mycotaki by Metagenics Drug Interactions

Want to check YOUR meds against Mycotaki?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
997Drugs
955 Moderate 42 Minor

Ingredients driving the most interactions

Poria cocos Sclerotium Extract 417
Reishi fruiting body extract 375
Shiitake Fruiting Body Extract 312
Maitake Fruiting Body Extract 260
Cordyceps Mycelia Extract 249

Individual Drug Interactions

The ingredients in Mycotaki interact with 997 drugs. Click any drug to see the details.

6 of the 7 ingredients in Mycotaki interact with drugs. Each result below shows which ingredient is responsible. Poria cocos Sclerotium Extract Reishi fruiting body extract Shiitake Fruiting Body Extract Maitake Fruiting Body Extract Cordyceps Mycelia Extract Turkey Tail Mushroom Fruiting Body Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Mycotaki with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Poria cocos Sclerotium Extract3 drug types · 417 drugs

Anticholinergic Drugs

Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Poria cocos Sclerotium Extract full monograph & interactions

Reishi fruiting body extract3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi fruiting body extract full monograph & interactions

Shiitake Fruiting Body Extract2 drug types · 312 drugs

Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
In vitro studies suggest that the shiitake mushroom extract AHCC might induce the CYP2D6 enzyme. This effect has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking shiitake mushroom might decrease the effects of immunosuppressive therapy.
In vitro evidence suggests that shiitake mushroom extracts stimulate immune function.

Likelihood Possible Evidence D
Shiitake Fruiting Body Extract full monograph & interactions

Maitake Fruiting Body Extract3 drug types · 260 drugs

Antidiabetes Drugs

Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.

Likelihood Possible Evidence D
Maitake Fruiting Body Extract full monograph & interactions

Cordyceps Mycelia Extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
Cordyceps Mycelia Extract full monograph & interactions

Turkey Tail Mushroom Fruiting Body Extract4 drug types · 187 drugs

Antidiabetes Drugs

Theoretically, taking turkey tail mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that turkey tail mushroom and a polysaccharide component can have hypoglycemic effects.

Likelihood Possible Evidence D
Cyclophosphamide

Theoretically, the polysaccharide peptide (PSP) component of turkey tail mushroom might increase exposure to cyclophosphamide.
Some animal research shows that the PSP component of turkey tail mushroom can increase the area under the concentration-time curve (AUC) of cyclophosphamide by 44% to 50% and the half-life by 34% to 43%. This interaction could potentially increase the effects and adverse effects of cyclophosphamide. However, it is not known whether PSP affects the levels of the active metabolites of cyclophosphamide that are responsible for its clinical activity.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, the polysaccharide peptide (PSP) component of turkey tail mushroom might interfere with the absorption of tamoxifen.
Animal research suggests that PSP increases the time to reach maximum concentration of a single dose of tamoxifen by about 9.5 hours, or 228%. When repeated doses of tamoxifen were given, the time to reach maximum concentration was increased by about 5.6 hours, or 93%. However, PSP did not affect the maximum concentration or the area under the curve of tamoxifen.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, the polysaccharide peptide (PSP) component of turkey tail mushroom might inhibit CYP2C9.
Laboratory research suggests that the PSP component of turkey tail mushroom dose-dependently inhibits CYP2C9. Theoretically, taking PSP with drugs metabolized by CYP2C9 might increase drug levels and the risk of adverse effects. However, this has not been reported in humans.

Likelihood Possible Evidence D
Turkey Tail Mushroom Fruiting Body Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mycotaki, from the product label.

Metagenics

See all Metagenics products
Name
Metagenics
City
Gig Harbor
State
WA
ZipCode
98332
Phone Number
800 692 9400
Pharmacist Counseling Corner

Mycotaki by Metagenics: Common Questions

Does Mycotaki by Metagenics interact with any medications?
Yes. Based on its ingredients, Mycotaki has a known interaction with 997 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mycotaki contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
The safety data for all six mushroom extracts we checked—poria, reishi, shiitake, maitake, turkey tail, and cordyceps—are not sufficient to know either way, and the available information advises against use during pregnancy and breastfeeding. Talk with your doctor or pharmacist for personalized guidance.
What does turkey tail mushroom do in this blend?
Turkey tail is rated possibly effective for cancer support based on current evidence, though more research is needed. The others—poria, reishi, shiitake, maitake, and cordyceps—have insufficient evidence to say whether they work for their intended purposes.
What are the most common side effects?
Gastrointestinal upset—nausea, diarrhea, stomach discomfort, and bloating—is the most common mild side effect across these mushroom extracts. Dizziness, dry mouth, rash, and itching have also been reported. Shiitake can cause skin reactions, especially if raw.
Can I take this long-term?
Long-term safety data are limited for all these mushroom extracts. Short-term use appears generally well tolerated, but you should check with your doctor or pharmacist about extended use and whether it's right for your situation.
Does this product have fillers or other inactive ingredients?
Yes. Besides the active mushroom extracts, the tablet contains inactive ingredients including microcrystalline cellulose, cellulose, stearic acid, croscarmellose sodium, silica, hypromellose, medium chain triglyceride, and hydroxypropyl cellulose, which serve as binders and capsule materials.
What's the proprietary blend?
The proprietary blend is a container for the product's active mushroom extracts. The individual ingredients—poria, reishi, shiitake, oyster mushroom, maitake, turkey tail, and cordyceps—are listed separately so you can see what's in it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mycotaki is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mycotaki label
Go deeper

The Full Monographs Behind Mycotaki’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Poria Mushroom

Interacts with 417 drugs

Poria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...

Read the full Poria Mushroom monograph → Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph → Herb & supplement monograph

Shiitake Mushroom

Interacts with 312 drugs

Shiitake is a popular edible mushroom that is nutritious and safe to eat as food for most people. Some of its extracts (like lentinan and AHCC) have been studied as immune support, mainly al...

Read the full Shiitake Mushroom monograph → Herb & supplement monograph

Maitake Mushroom

Interacts with 260 drugs

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...

Read the full Maitake Mushroom monograph → Herb & supplement monograph

Turkey Tail Mushroom

Interacts with 187 drugs

Turkey tail is a woodland mushroom rich in polysaccharides like beta-glucans, and it is mainly used to support the immune system. Some of its purified extracts (PSK and PSP) have been studie...

Read the full Turkey Tail Mushroom monograph → Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph →
Sources

Sources & How We Checked

Mycotaki's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 124 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Poria Mushroom 3 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
  3. Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.

See these in context on the Poria Mushroom monograph →

Reishi Mushroom 17 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
  3. Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
  4. Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
  5. Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
  6. Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
  7. Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
  8. Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
  9. Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
  10. Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
  11. Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
  12. Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
  13. Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
  14. Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
  15. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
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Shiitake Mushroom 67 references
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Maitake Mushroom 8 references
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Turkey Tail Mushroom 15 references
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Cordyceps 14 references
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