PHOSFLEX Creatine Sugar Free Fruit Punch Ingredients & Drug Interactions
What is this page for?
First and foremost: checking PHOSFLEX Creatine Sugar Free Fruit Punch against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
PHOSFLEX Creatine Sugar Free Fruit Punch is a dietary supplement by Betancourt Nutrition with 4 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 205 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against PHOSFLEX Creatine Sugar Free Fruit Punch by Betancourt Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with PHOSFLEX Creatine Sugar Free Fruit Punch by Betancourt Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of PHOSFLEX Creatine Sugar Free Fruit Punch by Betancourt Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
PHOSFLEX Creatine Sugar Free Fruit Punch contains 2 active ingredients: sodium and the Phosflex Blend. The product also includes inactive ingredients — natural and artificial flavors, citric acid, silica, and artificial colors — that serve as thickeners, binders, and flavor agents.
Does it work?
Couldn't assess
Sodium's effectiveness is established for cystic fibrosis, where it is likely effective. For amphotericin B nephrotoxicity (kidney damage from a fungal antibiotic), sodium is possibly effective.
We hold insufficient reliable evidence to rate sodium's role in bipolar disorder or congestive heart failure. We could not check the effectiveness of the Phosflex Blend — no data is on file for it.
How safe is it?
Well-documented data
Sodium is generally well tolerated at normal dietary amounts — up to the recommended daily intake level. Too much sodium, especially from supplements or very high intake, is linked to high blood pressure, heart strain, and kidney disease.
Serious adverse effects from excess sodium are rare but include worsened cardiovascular disease, hypertension, and kidney damage. Population studies have found that high sodium intake is associated with an increased risk of gastric cancer.
For pregnancy and lactation, sodium is rated likely safe, though one entry rates it possibly unsafe — talk with your doctor or pharmacist about what that means for your personal situation. Normal dietary sodium is fine; avoid sodium supplements or very high intake without medical advice.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take blood pressure medications, lithium, corticosteroids, didanosine, sodium phosphates, tolvaptan, or any other sodium-containing drugs. All of these carry Moderate-severity interaction risk with the sodium in this product.
The bottom line
Scorecard at a glancePartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is sodium-based, so it's not right for anyone taking blood pressure medications, lithium, corticosteroids, or other sodium-sensitive drugs without their doctor's approval. If you have high blood pressure, heart disease, or kidney problems, check with your doctor or pharmacist before using it — sodium intake matters for these conditions.
Even if you're generally healthy, run your medications through the checker on this page before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about PHOSFLEX Creatine Sugar Free Fruit Punch, straight from the product label.
| Brand | Betancourt Nutrition |
|---|---|
| Barcode (UPC) | 857487003150 |
| Net contents | 2.5 lbs; 1125 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Oct 25, 2012 |
| DSLD ID | 12900 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for PHOSFLEX Creatine Sugar Free Fruit Punch by Betancourt Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 200 {Calories} | 10% |
| Total Carbohydrates | 30 g | 8% |
| Sugar | 0 g | -- |
| Calories from Fat | 45 {Calories} | -- |
| Total Fat | 5 g | 8% |
| Protein | 0 g | -- |
| Saturated Fat | 0 g | -- |
| Sodium | 0 g | -- |
| Cholesterol | 0 g | -- |
| Phosflex Blend | 45000 mg | -- |
Other ingredients: Natural and artificial flavors, Citric Acid, Silica, artificial colors
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Recommended Usage: Phosflex(TM) is the 'World's First Flexible Creatine Drink Mix' which features a Joint Support, Insulin, and Muscle Volumizing Complex making it perfect for use pre, during or post workout. NO loading phase is required thanks to it's advanced 3-Energy Creatine Complex featuring Di-Creatine Malate which is responsible for minimizing water retention and increasing energy production from the powerhouse centers of your muscle cells (the mitochondria). However, to maintain elevated creatine levels, Phosflex(TM) can be stacked with Creatine Micro Chewies(TM), on non-training days.
- Banaba Leaf Powder Extract: Banaba (Lagerstroemia speciosa) contains corosolic acid (CA), a pentacyclic triterpene that supports glucose levels in the healthy range. Though its mechanism of action is unclear, studies suggest that it can increase glucose uptake in muscle cells, thereby supporting recovery.
-(1,3)(1,6) Beta-D-Glucan Powder: BDG is a naturally-occurring insoluble carbohydrate. Animal studies suggest that BDG is a potent immune system modulator that may reduce inflammation, a common symptom of heavy training. BDG has even been shown to have anabolic (building) effects on bone.
THE WORLD'S FIRST FLEXIBLE CREATINE DRINK MIX!
(image) Joints Insulin Muscles JOINTS: Joint Support Complex MUSCLE: 3-Energy Creatine Complex INSULIN: Insulin Fuel Support Complex
PRO GRADE
SUPPORT CREATINE & GLUCOSE LEVELS - ZERO LOADING!
- Glycerol Monostearate: Inside the body, GM releases glycerol. Glycerol is hydroscopic, which means that it draws water around itself. When glycol accumulates inside muscle and joint tissues, it hydrates and volumizes them, which provides hydraulic support.
- L-Tyrosine: Tyrosine is a precursor to neurotransmitters involved in the regulation of mood. Supplementation with tyrosine appears to be most helpful under conditions of mental stress.
- Potassium Bicarbonate: PB supplies the essential electrolyte potassium and helps buffer acid produced in muscle during high-intensity exercise.
Phone: 302-593-9296 - Fax: 202-449-8275
VOLUME CELLULAR EXPANSION! INSULIN ANABOLIC STORAGE!
Strength, Muscularity, & Joint Support
- Increase Glut-4 Translocation for Carbohydrate Use
Your muscles are not the only thing undergoing immense pressure when you're at the gym; your connective tissues must also bear the load as you tear through every set. Most products only focus on boosting performance or increasing muscle mass...but how many times have your ailing joints held you back at the gym?
It supports ATP re-synthesis by increasing muscle levels of phosphocreatine. The addition of di-creatine malate and creatine alpha-ketoglutarate to PHOSFLEX(TM) takes ATP re-synthesis to another level - three levels, in fact. While creatine increases muscle phosphocreatine levels, malate and alpha-ketoglutarate support the function of the tricarboxylic acid (TCA) cycle, a metaboloc pathway involved in the re-synthesis of ATP.
Glucose Polymers: GPs are possibly the fastest-acting, purest way to deliver glucose to your body. They can be digested and absorbed very quickly, making them ideal for fast recovery of glycogen levels post-workout.
Suggested/Recommended/Usage/Directions
If you choose to take creatine daily, continue for 6 weeks before discontinuing use for 2 weeks and then repeating. Continuous cycling of Phosflex(TM) is recommeded to enhance recovery, strength, maximize glycogen levels, and promote joint health. For regular use, mix 1 scoop (45g) mixed with 8 oz. of water or more based on your desired preference for consistency. Consume pre, during, or post-workout on training days; Phosflex(TM) can be consumed 30 minutes prior to exercise when combined with Recelerator(TM) for non-stimulant performance enhancement. Phosflex(TM) can also be taken within 1 hour post-exercise to restore glycogen levels when combined with Androrush(TM), (pre-workout), and Recelerator(TM) (post-workout) for maximum gains in performance, size, and recovery.
Brand IP Statement(s)
- Leucine Nitrate(TM): The branched-chain amino acid (BCAA) leucine turns on "switches" inside your muscle cells that allow rates of muscle protein synthesis to increase after resistance exercise. The nitrate attached to leucine can be converted into nitric oxide (NO), a potent vasodilator and regulator of muscle blood flow.
Betancourt Nutrition proudly introduces the new PHOSFLEX(TM) Creatine for athletes at the highest level of competition.
Whether you're a beginner or advanced, new PHOSFLEX(TM) is the only creatine formula designed by the physiologists at Betancourt Nutrition to simultaneously provide muscle glycogen replenishment, joint support, and unmatched increases in strength and muscle mass. Only PHOSFLEX(TM) CONTAINS:
FDA Statement of Identity
POWDER DIETARY SUPPLEMENT
Formula
Contains: Shellfish (Shrimp, Crab)
- 2000mg Chondroitin Sulfate & Glucosamine HCL - L-Leucine Nitrate(TM)
1,3-1,6-Beta-D-Glucan For Stronger Bones
- 5000mg Creatine
- 3-Energy Creatin Complex: 5,000mg of Creatine Monohydrate is the most studied and proven form of creatine.
Precautions
WARNING: Seek the advice of a health care practitioner before use.
Not suggested for use by children under the age of 18 or in people who have been diagnosed with hypertension, kidney disease, liver disease, metabolic syndrome, diabetes, neoplastic condition such as cancer or thalassemia.
Do not use if pregnant or nursing.
KEEP OUT OF REACH OF CHILDREN.
Storage
STORE IN A COOL DRY PLACE.
Seals/Symbols
LABORATORY TESTED BY nfn
WHATEVER IT TAKES!(R)
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
PHOSFLEX Creatine Sugar Free Fruit Punch by Betancourt Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in PHOSFLEX Creatine Sugar Free Fruit Punch by Betancourt Nutrition
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size45 Gram(s) Dosage formPowder Servings per container25 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
Protein
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsPhosflex Blend
Other (inactive) ingredients: Natural and artificial flavors, Citric Acid, Silica, Artificial colors. These complete the product’s ingredient list but are not active constituents.
PHOSFLEX Creatine Sugar Free Fruit Punch by Betancourt Nutrition Drug Interactions
HelloPharmacist Interaction Report
PHOSFLEX Creatine Sugar Free Fruit Punch contains sodium, which interacts with blood pressure medications (antihypertensives), corticosteroids, lithium, didanosine, sodium phosphates, tolvaptan, and other sodium-containing drugs — all at Moderate severity.
The main concern is that extra sodium can counteract blood pressure control or trigger dangerously high sodium levels (hypernatremia) when combined with certain medications.
Read the full breakdown — every affected drug type, severity by severity
High sodium intake can reduce how well blood pressure medications work by raising your systolic and diastolic pressure, sometimes requiring your doctor to increase doses. With corticosteroids, lithium, didanosine, sodium phosphates, tolvaptan, and sodium-containing drugs, added sodium boosts your risk of hypernatremia — a condition where your blood sodium climbs too high.
Lithium deserves special attention: high sodium can lower lithium levels and reduce its effect, while low sodium can push lithium levels dangerously high and cause toxicity.
We could not check the Phosflex Blend ingredient — no interaction data is on file for it. Before you take this product, check your exact medications using the tool on this page.
Altogether, these interactions span 205 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against PHOSFLEX Creatine Sugar Free Fruit Punch?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in PHOSFLEX Creatine Sugar Free Fruit Punch interact with 205 drugs. Click any drug to see the details.
1 of the 4 ingredients in PHOSFLEX Creatine Sugar Free Fruit Punch interact with drugs. Each result below shows which ingredient is responsible. Sodium
AcebutololRhotral, Sectral
How Acebutolol interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlorthalidone interactionAzelastine Hydrochloride, Fluticasone PropionateDymista
How Azelastine Hydrochloride, Fluticasone Propionate interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Azelastine Hydrochloride, Fluticasone Propionate interactionAzilsartanEdarbi
How Azilsartan interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Azilsartan, Chlorthalidone interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Beclomethasone Dipropionate interactionBenazeprilLotensin
How Benazepril interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Benzthiazide interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with PHOSFLEX Creatine Sugar Free Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Betamethasone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in PHOSFLEX Creatine Sugar Free Fruit Punch with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for PHOSFLEX Creatine Sugar Free Fruit Punch, from the product label.
Betancourt Nutrition
See all Betancourt Nutrition products- Name
- Betancourt Nutrition, Inc.
- Street Address
- 14620 NW 60th Ave.
- City
- Miami Lakes
- State
- Florida
- ZipCode
- 33014
- Phone Number
- 800-443-4153
- Web Address
- www.betancourtnutrition.com
PHOSFLEX Creatine Sugar Free Fruit Punch by Betancourt Nutrition: Common Questions
Does PHOSFLEX Creatine Sugar Free Fruit Punch by Betancourt Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this product have a lot of sodium in it?
Can I take this if I'm on blood pressure medication?
What's the Phosflex Blend, and what does it do?
Is this product safe to use during pregnancy?
Can I take this if I'm on lithium?
What are the side effects of sodium in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if PHOSFLEX Creatine Sugar Free Fruit Punch is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind PHOSFLEX Creatine Sugar Free Fruit Punch’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
PHOSFLEX Creatine Sugar Free Fruit Punch's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
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The 38 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
- Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
- Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
- Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
- Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
- Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
- Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
- Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
- Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
- Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
- D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
- Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
- Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
- Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
- Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
- Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
- Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
- Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
- O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
- Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
- Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
- Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
- Yancy CW. Sodium Restriction in Heart Failure: Too Much Uncertainty-Do the Trials. JAMA Intern Med. 2018 Dec 1;178(12):1700-1701. PubMed
- He FJ, Campbell NRC, Ma Y, MacGregor GA, Cogswell ME, Cook NR. Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health. Int J Epidemiol. 2018;47(6):1784-1795. PubMed
- Murthy K, Ondrey GJ, Malkani N, et al. THE EFFECTS OF HYPONATREMIA ON BONE DENSITY AND FRACTURES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Endocr Pract. 2019;25(4):366-378. PubMed
- Messerli FH, Hofstetter L, Syrogiannouli L, et al. Sodium intake, life expectancy, and all-cause mortality. Eur Heart J 2021;42(21):2103-2112. PubMed
- Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev 2020;12(12):CD004022. PubMed
- Giatti S, Santos RB, Aielo AN, et al. Association of sodium with obstructive sleep apnea. The ELSA-Brasil study. Ann Am Thorac Soc 2021;18(3):502-510. PubMed
- Nan X, Lu H, Wu J, et al. The interactive association between sodium intake, alcohol consumption and hypertension among elderly in northern China: a cross-sectional study. BMC Geriatr 2021;21(1):135. PubMed
- Kyozuka H, Fukusda T, Murata T, et al. Impact of preconception sodium intake on hypertensive disorders of pregnancy: The Japan Environment and Children's study. Pregnancy Hypertens 2021;23:66-72. PubMed
- Zhao L, Ogden CL, Yang Q, et al. Association of usual sodium intake with obesity among US children and adolescents, NHANES 2009-2016. Obesity (Silver Spring) 2021;29(3):587-594. PubMed
- Ma Y, He FJ, Sun Q, et al. 24-Hour urinary sodium and potassium excretion and cardiovascular risk. N Engl J Med 2022;386(3):252-263. PubMed
- Liu J, Yang X, Zhang P, et al. Association of urinary sodium excretion and left ventricular hypertrophy in people with type 2 diabetes mellitus: A cross-sectional study. Front Endocrinol (Lausanne) 2021;12:728493. PubMed
- Filippini T, Malavolti M, Whelton PK, Vinceti M. Sodium intake and risk of hypertension: A systematic review and dose-response meta-analysis of observational cohort studies. Curr Hypertens Rep 2022;24(5):133-144. PubMed
- Wang DD, Li Y, Nguyen XT, et al. Dietary sodium and potassium intake and risk of non-fatal cardiovascular diseases: The million veteran program. Nutrients 2022;14(5):1121. PubMed
- Kwak JH, Park CH, Eun CS, et al. The associations of dietary intake of high sodium and low zinc with gastric cancer mortality: A prospective cohort study in Korea. Nutr Cancer 2022;74(10):3501-3508. PubMed
- George S, Maiti R, Mishra BR, Jena M, Mohapatra D. Effect of regulated add-on sodium chloride intake on stabilization of serum lithium concentration in bipolar disorder: A randomized controlled trial. Bipolar Disord 2023;25(1):66-75. PubMed
- Zhou TL, Schütten MTJ, Kroon AA, et al. Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population. J Am Heart Assoc 2023;12(1):e026578. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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