Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Phyto-Gen Uri-gen Ingredients & Drug Interactions

by Genestra Brands

Phyto-Gen Uri-gen label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Phyto-Gen Uri-gen against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Phyto-Gen Uri-gen is a dietary supplement by Genestra Brands with 3 active ingredients. Its ingredients are commonly taken for water retention (diuretic), digestive upset and bloating, urinary tract support.Based on those ingredients, 266 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are European Ash (Fraxinus excelsior) bud extract, Juniper (Juniperus communis) young shoot extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Phyto-Gen Uri-gen by Genestra Brands

Ask about any prescription or over-the-counter medication and we check it for interactions with Phyto-Gen Uri-gen by Genestra Brands — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Phyto-Gen Uri-gen by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Phyto-Gen Uri-gen contains 3 active ingredients: juniper young shoot extract, silver birch bud extract, and European ash bud extract. These are combined in a liquid base of water, purified ethanol (alcohol), and glycerin.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Urinary tract and bladder health support.
  • We looked for evidence on: Urinary tract infections (UTIs), Kidney stones (nephrolithiasis), Urinary frequency, Bladder comfort.
  • The closest evidence on file: Juniper is rated "Insufficient Reliable Evidence To Rate" for Kidney stones (nephrolithiasis) (Natural Medicines).
  • Also on file: Juniper is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs).

The evidence supporting juniper for urinary tract infections, kidney stones, wound healing, GERD, rheumatoid arthritis, and bronchitis is insufficient to rate — meaning we don't have solid data either way. The same is true for ash and obesity.

So far, the data we hold doesn't establish that this product works for the conditions it's marketed for.

The evidence, ingredient by ingredient Juniper Ash

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Juniper is generally well tolerated at food doses, but medicinal amounts may irritate your kidneys and shouldn't be used long-term. Topically, juniper can cause skin irritation, allergies, and in rare cases burn-like lesions, especially with sun exposure.

Ash lacks strong safety data at medicinal doses. Neither ingredient should be used during pregnancy — juniper is considered unsafe, and ash has insufficient safety information.

While breastfeeding, both juniper and ash are best avoided because there isn't enough safety data. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Juniper Ash

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Ash, Juniper.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 266 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood sugar and blood pressure medications first — juniper and ash may both lower blood glucose and blood pressure, increasing the risk of low blood sugar or dangerously low blood pressure. Also double-check if you take diuretics (water pills) or lithium, as juniper can interfere with both.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is marketed for urinary and kidney concerns, but the evidence for those uses isn't established in our data. The bigger issue is the interaction risk with blood sugar, blood pressure, and certain other medications.

If you take any prescription drugs — especially for diabetes, high blood pressure, water retention, or if you take lithium — check with your doctor or pharmacist before adding this supplement. It's not appropriate during pregnancy or while breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phyto-Gen Uri-gen, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 883196120710
Net contents 0.5 Fluid Ounce(s); 15 mL
Market status On market
Date entered into DSLD May 19, 2022
DSLD ID 264506
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phyto-Gen Uri-gen by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.28 mL
Maximum serving Sizes:
0.28 mL
Servings per container
53
UPC/BARCODE
883196120710
IngredientAmount% DV
Juniper (Juniperus communis) young shoot extract0.09 mL--
Silver Birch (Betula pendula) bud extract0.09 mL--
European Ash (Fraxinus excelsior) bud extract0.09 mL--

Other ingredients: Water, Purified, Ethanol, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Take 10 drops once daily or as recommended by your health professional. Invert bottle to 45 degrees and shake lightly allowing drops to fall directly into mouth or in 1/4 oz of water.

Precautions

For warnings and additional information, see outer box.

Keep out of the reach of children.

Use only if safety seal is intact.

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

This product was sealed for your protection. Do not use if box or contents are open or damaged.

Storage

Store in a cool, dry place.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Scan to learn about our quality excellence V2 860-15U

FDA Statement of Identity

Dietary Supplement

Formula

Silver Birch Juniper European Ash

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Phyto-Gen Uri-gen by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Phyto-Gen Uri-gen label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Phyto-Gen Uri-gen by Genestra Brands

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.28 mL Dosage formLiquid Servings per container53 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Juniper (Juniperus communis) young shoot extract

Interacts with
162 drugs
0.09 mL per serving

Juniper berry is a traditional herb best known for flavoring gin and for its folk use as a diuretic and digestive aid. Solid human evidence for its he...

Juniper (Juniperus communis) young shoot extract monograph & interactions

Silver Birch (Betula pendula) bud extract

0.09 mL per serving

European Ash (Fraxinus excelsior) bud extract

Interacts with
258 drugs
0.09 mL per serving

Ash (Fraxinus excelsior and related species) is a tree whose leaves, bark, and seeds have a long history in folk medicine for arthritis, fever, and fl...

European Ash (Fraxinus excelsior) bud extract monograph & interactions

Other (inactive) ingredients: Water, Purified, Ethanol, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phyto-Gen Uri-gen by Genestra Brands Drug Interactions

Want to check YOUR meds against Phyto-Gen Uri-gen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
266Drugs
258 Moderate 8 Minor

Ingredients driving the most interactions

European Ash (Fraxinus excelsior) bud extract 258
Juniper (Juniperus communis) young shoot extract 162

Individual Drug Interactions

The ingredients in Phyto-Gen Uri-gen interact with 266 drugs. Click any drug to see the details.

2 of the 3 ingredients in Phyto-Gen Uri-gen interact with drugs. Each result below shows which ingredient is responsible. European Ash (Fraxinus excelsior) bud extract Juniper (Juniperus communis) young shoot extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Phyto-Gen Uri-gen with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

European Ash (Fraxinus excelsior) bud extract2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, concomitant use with antidiabetes drugs might affect glucose control and increase the risk of hypoglycemia. Dose adjustments to diabetes medications might be necessary. Animal research shows that ash seed/fruit extract reduces fasting levels of glucose. Although clinical research in patients without diabetes shows that ash seed/fruit extract does not significantly affect blood glucose levels, insulin levels, or homeostatic model of insulin resistance (HOMA-IR), it may lower the incremental glucose area under the curve and decrease 2-hour blood glucose following an oral glucose tolerance test. Ash seed/fruit extract has not been evaluated in patients with diabetes. Until more is known, use cautiously in patients taking antidiabetes drugs.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of ash seed with antihypertensive drugs might have additive blood pressure lowering effects. Animal research shows that ash seed extract can decrease blood pressure. This effect has not been evaluated in humans. Until more is known, use cautiously in patients taking antihypertensive drugs.
Some antihypertensive drugs include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.

Likelihood Possible Evidence D
European Ash (Fraxinus excelsior) bud extract full monograph & interactions

Juniper (Juniperus communis) young shoot extract3 drug types · 162 drugs

Antidiabetes Drugs

Theoretically, taking juniper berry with antidiabetes medications might cause additive hypoglycemia.
Animal research shows that juniper berry can lower blood glucose.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, juniper berry might increase the risk of adverse effects from diuretic drugs.
Juniper berry is thought to have mild diuretic effects.

Likelihood Possible Evidence D
Lithium

Theoretically, juniper berry might reduce lithium excretion and increase serum levels of lithium.
Juniper berry is thought to have mild diuretic effects.

Likelihood Possible Evidence D
Juniper (Juniperus communis) young shoot extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Phyto-Gen Uri-gen, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

Phyto-Gen Uri-gen by Genestra Brands: Common Questions

Does Phyto-Gen Uri-gen by Genestra Brands interact with any medications?
Yes. Based on its ingredients, Phyto-Gen Uri-gen has a known interaction with 266 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Phyto-Gen Uri-gen contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against it. Juniper is considered unsafe in pregnancy, and both juniper and ash lack enough safety information for breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you at this time.
Does this actually work for urinary tract infections or kidney stones?
The evidence we have is insufficient to say. The studies aren't solid enough to rate whether juniper or ash helps with UTIs, kidney stones, or any of the other conditions this product targets.
Is juniper safe to use long-term?
Not according to our data. While juniper is generally well tolerated at food amounts and short-term medicinal doses, long-term use at medicinal strength may irritate your kidneys, so it's not recommended for ongoing treatment.
What are the side effects I should watch for?
Orally, juniper appears generally well tolerated at low doses in the short term, though a full safety review hasn't been done. Topically, it can cause skin irritation and allergies; in rare cases, especially with sun exposure, it's caused burn-like blistering. Repeated pollen exposure can trigger occupational allergies affecting skin or breathing.
Why do I need to check so many medications?
Juniper and ash both have the ability to lower blood sugar and blood pressure through effects that mimic what many medications do. When you add an herb that does the same thing, the combined effect can be too strong, raising the risk of low blood sugar or a dangerous blood pressure drop.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phyto-Gen Uri-gen is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phyto-Gen Uri-gen label
Go deeper

The Full Monographs Behind Phyto-Gen Uri-gen’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Juniper

Interacts with 162 drugs

Juniper berry is a traditional herb best known for flavoring gin and for its folk use as a diuretic and digestive aid. Solid human evidence for its health benefits is limited, and it can irr...

Read the full Juniper monograph → Herb & supplement monograph

Ash

Interacts with 258 drugs

Ash (Fraxinus excelsior and related species) is a tree whose leaves, bark, and seeds have a long history in folk medicine for arthritis, fever, and fluid retention. Solid human evidence is l...

Read the full Ash monograph →
Sources

Sources & How We Checked

Phyto-Gen Uri-gen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Juniper 7 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  5. Sanchez de Medina F, Gamez MJ, Jimenez I, et al. Hypoglycemic activity of juniper "berries." Planta Med 1994;60:197-200. PubMed
  6. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  7. Tammaro A, Adebanjo GAR, Chello C, et al. Bullous dermatitis caused by common juniper. Contact Dermatitis. 2020. PubMed

See these in context on the Juniper monograph →

Ash 3 references
  1. Zulet MA, Navas-Carretero S, Lara y Sánchez D, et al. A Fraxinus excelsior L. seeds/fruits extract benefits glucose homeostasis and adiposity related markers in elderly overweight/obese subjects: a longitudinal, randomized, crossover, double-blind,
  2. Montó F, Arce C, Noguera MA, et al. Action of an extract from the seeds of Fraxinus excelsior L. on metabolic disorders in hypertensive and obese animal models. Food Funct. 2014;5(4):786-96. PubMed
  3. Visen P, Saraswat B, Visen A, et al. Acute effects of Fraxinus excelsior L. seed extract on postprandial glycemia and insulin secretion on healthy volunteers. J Ethnopharmacol. 2009;126(2):226-32. PubMed

See these in context on the Ash monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team