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Dietary supplement

Pitahaya Ingredients & Drug Interactions

by Hawaii Pharm

Pitahaya label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pitahaya against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pitahaya is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, digestive health and regularity, blood sugar support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pitahaya Fruit Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pitahaya by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Pitahaya by Hawaii Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Pitahaya by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pitahaya fruit extract in dry form, commonly known as dragon fruit. The supplement is delivered in liquid form using alcohol, water, and glycerin as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Dragon Fruit product and its label doesn't state a use — see Dragon Fruit's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold shows insufficient reliable data to rate dragon fruit extract for managing diabetes or prediabetes (impaired glucose tolerance). While dragon fruit is widely eaten as a food, we don't have solid research backing its use as a concentrated supplement for these conditions.

The evidence, ingredient by ingredient Dragon Fruit

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Dragon fruit as a food is generally well tolerated and widely consumed around the world. However, the concentrated extract form in this supplement hasn't been studied in pregnancy or while breastfeeding — so the safety data for supplement use isn't available.

Talk with your doctor or pharmacist about whether to use it during pregnancy or lactation. Allergy to dragon fruit has been reported in rare case reports, with symptoms including vomiting, swollen tongue, skin redness, and hives — though this appears uncommon.

Side effects, ingredient by ingredient Dragon Fruit

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Dragon Fruit.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you're on any antidiabetes medication — including insulin, glimepiride, glyburide, or other drugs that lower blood sugar. The extract may amplify that effect and raise your risk of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have prediabetes or diabetes and your blood sugar is well controlled, this extract might interest you — but the evidence for its effectiveness is limited. The real concern is its potential to lower blood sugar when combined with diabetes medications, which could be risky.

Talk with your doctor or pharmacist before you start, especially if you're on any blood sugar medication.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pitahaya, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 842056341533
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 301754
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pitahaya by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
842056341533
IngredientAmount% DV
Pitahaya Fruit Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Organic Alcohol Based USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get more info or reorder

Formula

Hylocereus undatus

Organic Alcohol Based

Formulation

Only natural ingredients Identity and purity is laboratory verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pitahaya by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pitahaya label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pitahaya by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Pitahaya Fruit Extract, Dry

Interacts with
86 drugs
983 mg per serving Form: Hylocereus undatus Fruit Extract, Dry

Dragon fruit is a colorful tropical fruit that is a nutritious, low-calorie source of fiber, vitamin C, and antioxidants. It is safe and healthy to ea...

Pitahaya Fruit Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pitahaya by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Pitahaya?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Pitahaya Fruit Extract, Dry 86

Individual Drug Interactions

The ingredients in Pitahaya interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pitahaya interact with drugs. Each result below shows which ingredient is responsible. Pitahaya Fruit Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Pitahaya with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pitahaya Fruit Extract, Dry1 drug type · 86 drugs

Antidiabetes Drugs

Dragon fruit might lower blood glucose levels. Theoretically, it might have additive effects when used with antidiabetes drugs. This might increase the risk of hypoglycemia in some patients. Dose adjustments to diabetes medications might be necessary.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Pitahaya Fruit Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pitahaya, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Pitahaya by Hawaii Pharm: Common Questions

Does Pitahaya by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Pitahaya has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pitahaya contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The concentrated extract form hasn't been studied in pregnancy or while nursing, so there isn't enough data to know whether it's safe. Talk with your doctor or pharmacist for personalized advice — they can weigh the risks and benefits for your situation.
Does dragon fruit really lower blood sugar?
Dragon fruit may lower blood glucose levels, which is why it could interact with diabetes medications. But the evidence we hold is insufficient to rate how well it actually works for managing diabetes or prediabetes as a supplement.
Is this safe to eat as a fruit?
Yes — dragon fruit eaten as a whole food is generally well tolerated and widely consumed worldwide. This liquid extract is more concentrated, though, so the safety profile may differ.
Can I be allergic to dragon fruit?
Allergy to dragon fruit is rare but has been reported. Symptoms in case reports included vomiting, swollen tongue, skin redness, and hives. If you experience any of these after taking it, stop and contact your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pitahaya is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pitahaya label
Go deeper

The Full Monographs Behind Pitahaya’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Dragon Fruit

Interacts with 86 drugs

Dragon fruit is a colorful tropical fruit that is a nutritious, low-calorie source of fiber, vitamin C, and antioxidants. It is safe and healthy to eat as a food for most people, but strong...

Read the full Dragon Fruit monograph →
Sources

Sources & How We Checked

Pitahaya's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dragon Fruit 2 references
  1. Kleinheinz A, Lepp U, Hausen BM, Petersen A, Becker WM. Anaphylactic reaction to (mixed) fruit juice containing dragon fruit. J Allergy Clin Immunol. 2009 Oct;124(4):841-2. PubMed
  2. Poolsup N, Suksomboon N, Paw NJ. Effect of dragon fruit on glycemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis. PLoS One. 2017;12(9):e0184577. PubMed

See these in context on the Dragon Fruit monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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