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Dietary supplement

Potassium Citrate Ingredients & Drug Interactions

by NOW

Potassium Citrate label
See full label image
Powder Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Potassium Citrate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Potassium Citrate is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Potassium Citrate by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Potassium Citrate by NOW — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Potassium Citrate by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Potassium” is listed as a grouped ingredient — the label gives one combined amount (448 mg) without saying how much of each component you get.

This product contains one active ingredient: potassium citrate, a form of potassium (an essential mineral) bound to citrate. The powder delivers potassium in a form your body can absorb from the digestive tract.

There are no inactive fillers or other ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: electrolyte balance and normal pH.
  • We looked for evidence on: hypokalemia, muscle function, fluid balance.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The product facts we hold do not include effectiveness ratings or trial data for potassium citrate, so we can't speak to how well it works or what dose restores normal blood levels. If you're considering this supplement, ask your doctor or pharmacist what the evidence shows for your particular reason for taking it.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium is generally well tolerated when taken by mouth. The most common side effects are mild digestive complaints — abdominal pain, belching, diarrhea, flatulence, nausea, and vomiting.

Serious side effects are rare but real: dangerously high blood potassium can cause irregular heartbeat, low blood pressure, and confusion. This risk is highest in people with kidney disease, so kidney function matters a lot.

During pregnancy, dietary potassium is appropriate, but use supplements only under medical guidance. The same applies to breastfeeding — check with your doctor before using supplements.

The safety data is rated as likely safe during pregnancy and lactation, but your individual situation needs a professional review.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist or doctor if you take potassium-sparing diuretics, ACE inhibitors, or angiotensin receptor blockers (ARBs) — all carry Moderate risk of dangerously high blood potassium when combined with supplements.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Potassium citrate is straightforward — one ingredient, easy to take. But it's not a casual supplement.

If you have kidney disease, take blood pressure or heart medications, or are pregnant or breastfeeding, you need to talk with your doctor or pharmacist before starting. Blood work may be needed to track your potassium level.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Potassium Citrate, straight from the product label.

Brand NOW
Barcode (UPC) 733739014467
Net contents 12 Ounce(s); 340 Gram(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 313975
Product type Mineral
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Potassium Citrate by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Level Teaspoon(s)
Maximum serving Sizes:
0.25 Level Teaspoon(s)
Servings per container
243
UPC/BARCODE
733739014467
IngredientAmount% DV
Potassium448 mg10%
Potassium Citrate1400 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1/4 level teaspoon 1 to 2 times daily in separate servings. Take with food and at least 8 oz. of water or other beverage. Do not exceed 2 servings per day.

Precautions

Do not exceed 2 servings per day.

Caution: For adults only.

Consult physician if pregnant/nursing, taking any medications (especially those that may affect kidney function or blood potassium levels), or have a medical condition (especially heart/kidney condition or diabetes).

Keep out of reach of children.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formula

Potassium is an essential mineral that is widely distributed among food sources, with especially high levels present in fruits and vegetables. Potassium is critical for the maintenance of normal whole-body and cellular fluid levels, as well as for the maintenance of acid-base balance. It is also necessary for proper muscle contraction, the maintenance of healthy heart function, and for the transmission of nerve impulses. Potassium Citrate is a well absorbed and highly bioavailable form of potassium.

Triangle K (Kosher)

Essential mineral

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Pure powder Supports Electrolyte Balance and Normal pH Proper Muscular Contraction

Vegetarian/Vegan

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

Natural color variation may occur in this product. Packaged and quality tested in the USA.

Non-GMO

FDA Statement of Identity

A Dietary Supplement

General Statements

Minerals Family owned since 1968.

Storage

This product is sold by weight not volume. Store in a cool, dry place after opening.

Seals/Symbols

GMP Quality Assured Triangle K (Kosher)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Potassium Citrate by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Potassium Citrate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Potassium Citrate by NOW

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Level Teaspoon(s) Dosage formPowder Servings per container243 Amounts shown are per serving.

Potassium

Interacts with
62 drugs
448 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions
Interaction report

Potassium Citrate by NOW Drug Interactions

Want to check YOUR meds against Potassium Citrate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Potassium Citrate interact with 62 drugs. Click any drug to see the details.

1 of the 1 ingredient in Potassium Citrate interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Potassium Citrate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Potassium Citrate, from the product label.

NOW

See all NOW products
Name
NOW Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Potassium Citrate by NOW: Common Questions

Does Potassium Citrate by NOW interact with any medications?
Yes. Based on its ingredients, Potassium Citrate has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Potassium Citrate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Who shouldn't take this?
Anyone with kidney disease should be especially cautious — kidney problems make it harder to clear excess potassium. Also talk to your doctor first if you take water pills that spare potassium, ACE inhibitors, or ARBs for blood pressure or heart health.
What are the most common side effects?
Digestive ones: belly pain, belching, diarrhea, gas, nausea, and vomiting. These are usually mild and happen when potassium supplements irritate your stomach.
Can I take this while pregnant or breastfeeding?
Dietary potassium from food is fine, but supplements need doctor approval. The safety data rates it as likely safe, but your doctor needs to weigh your individual situation before you start.
What is potassium citrate?
It's potassium (a mineral your body needs for heart, nerve, and muscle function) chemically bonded to citrate, which helps your body absorb it.
What happens if my blood potassium gets too high?
You could develop an irregular heartbeat, low blood pressure, weakness, confusion, or in rare cases, a life-threatening heart rhythm problem. This is why kidney health and drug interactions matter so much.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Potassium Citrate is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Potassium Citrate label
Go deeper

The Full Monographs Behind Potassium Citrate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Potassium Citrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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