Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Power Nitro Blood Vessels Ingredients & Drug Interactions

by Dr. Seth's Vitamin Vibrations

Power Nitro Blood Vessels label
See full label image
Powder Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Power Nitro Blood Vessels against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Power Nitro Blood Vessels is a dietary supplement by Dr. Seth's Vitamin Vibrations with 5 active ingredients. Its ingredients are commonly taken for high blood pressure, erectile dysfunction, athletic performance.Based on those ingredients, 409 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Arginine, Stevia Leaf Extract, L-Citrulline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Power Nitro Blood Vessels by Dr. Seth's Vitamin Vibrations

Ask about any prescription or over-the-counter medication and we check it for interactions with Power Nitro Blood Vessels by Dr. Seth's Vitamin Vibrations — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Power Nitro Blood Vessels by Dr. Seth's Vitamin Vibrations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains five active ingredients. L-arginine and L-citrulline are amino acids that work toward nitric oxide production and blood vessel relaxation.

L-proline is another amino acid. L-lysine is an amino acid used in some formulations for immune support.

Stevia leaf extract is a sweetener. The product also contains inactive ingredients — citric acid, pineapple juice powder, tropical fruit punch flavor, silica, and beet juice powder — which serve as fillers, flavoring, and texture agents.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support healthy nitric oxide levels and vascular health.
  • We looked for evidence on: Cardiovascular disease (CVD), Erectile dysfunction (ED), Hypertension, Heart failure, Endothelial function, Blood flow — and 1 related terms.
  • The closest evidence on file: Lysine is rated "Insufficient Reliable Evidence To Rate" for Hypertension (Natural Medicines).
  • Also on file: Stevia is rated "Insufficient Reliable Evidence To Rate" for Hypertension.
  • Also on file: L-citrulline is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Heart failure, Erectile dysfunction (ED), Postoperative pulmonary hypertension, and more.

The evidence we hold rates L-citrulline as possibly effective for athletic performance, but possibly ineffective for sarcopenia. For cardiovascular disease, heart failure, Reye syndrome, and diabetes, the evidence isn't strong enough to rate.

L-lysine is rated possibly effective for cold sores. L-proline's effectiveness for athletic performance, osteoporosis, fractures, wound healing, and osteopenia is not well established in the data we hold.

Stevia's effectiveness for diabetes, hypertension, and obesity is insufficient to rate. We have no effectiveness ratings for L-arginine in our data.

The evidence, ingredient by ingredient L-arginine L-citrulline Proline Lysine Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-arginine and L-citrulline are generally well tolerated short-term, but L-arginine safety for self-treatment isn't well established and should be used only under medical supervision. The most common side effects of oral L-arginine are abdominal pain, bloating, nausea, diarrhea, headache, insomnia, and flushing.

L-citrulline typically causes gastrointestinal discomfort and heartburn. L-lysine is generally well tolerated at typical doses but may cause abdominal pain, diarrhea, and indigestion at higher amounts.

Stevia appears well tolerated; minor effects like bloating, dizziness, headache, muscle pain, nausea, and numbness usually resolve within a week, though rare allergic reactions are possible. L-proline safety from supplements hasn't been well studied.

Side effects, ingredient by ingredient L-arginine L-citrulline Proline Lysine Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Lysine, Stevia, L-arginine, L-citrulline.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 409 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood pressure medications (including ACE inhibitors or ARBs), blood thinners (anticoagulants or antiplatelet drugs), diabetes medications, sildenafil (Viagra), potassium-sparing water pills, isoproterenol, 5-HT4 agonists, or lithium, check your exact medications with the tool below before using this product. The most serious risks are low blood pressure and high potassium levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is built around amino acids meant to support blood vessel function, but L-arginine and L-citrulline carry real interactions with blood pressure, heart, and diabetes medications. If you're on any prescription drugs — especially blood thinners, blood pressure meds, or heart medications — talk with your pharmacist before trying this.

Otherwise, it's generally tolerated, though it's not designed for self-treatment without medical input.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Power Nitro Blood Vessels, straight from the product label.

Brand Dr. Seth's Vitamin Vibrations
Barcode (UPC) 855524004399
Net contents 309 Gram(s); 10.9 Ounce(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 315831
Product type Botanical With Nutrients
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Power Nitro Blood Vessels by Dr. Seth's Vitamin Vibrations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10.3 Gram(s)
Maximum serving Sizes:
10.3 Gram(s)
Servings per container
30
UPC/BARCODE
855524004399
IngredientAmount% DV
L-Arginine3000 mg--
L-Citrulline3000 mg--
L-Proline1000 mg--
L-Lysine150 mg--
Stevia Leaf Extract180 mg--

Other ingredients: Citric Acid, Pineapple Juice, Powder, Tropical Fruit Punch Flavor, Silica, Beet Juice, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Color of this product may vary due to color variations of the natural ingredients.

A Dietary Supplement to support healthy nitric oxide levels & vascular health

Gluten free Soy free

Precautions

Warning: Persons with kidney or liver disorders or are taking blood thinning, blood pressure or erectile dysfunction medications should consult with their healthcare practitioner prior to using this product. If pregnant or nursing, consult your healthcare practitioner before taking this product.

Caution: Discontinue use 2 weeks prior to surgery. Jar contains desiccant to reduce moisture and clumping. Do not eat desiccant. If inner seal is broken, do not use.

Keep out of reach of children.

Storage

This product is packaged by weight, not by volume. Some settling may occur. Store in a cool, dry place at 59-86 Degrees F.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Dr. Seth's Vitamin Vibrations Energetic Infusion

FDA Statement of Identity

A Dietary Supplement to support healthy nitric oxide levels & vascular health

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, mix one scoop (10.3 g) per day in 8 oz. juice or water and take on an empty stomach or as directed by your healthcare practitioner.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Power Nitro Blood Vessels by Dr. Seth's Vitamin Vibrations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Power Nitro Blood Vessels label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Power Nitro Blood Vessels by Dr. Seth's Vitamin Vibrations

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size10.3 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Arginine

Interacts with
403 drugs
3000 mg per serving

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for bl...

L-Arginine monograph & interactions

L-Citrulline

Interacts with
178 drugs
3000 mg per serving

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...

L-Citrulline monograph & interactions

L-Proline

No known
interactions
1000 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

L-Lysine

Interacts with
1 drug
150 mg per serving

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...

L-Lysine monograph & interactions

Stevia Leaf Extract

Interacts with
259 drugs
180 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia Leaf Extract monograph & interactions

Other (inactive) ingredients: Citric Acid, Pineapple Juice, Powder, Tropical Fruit Punch Flavor, Silica, Beet Juice, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Power Nitro Blood Vessels by Dr. Seth's Vitamin Vibrations Drug Interactions

Want to check YOUR meds against Power Nitro Blood Vessels?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
409Drugs
400 Moderate 9 Minor

Ingredients driving the most interactions

L-Arginine 403
Stevia Leaf Extract 259
L-Citrulline 178
L-Lysine 1

Individual Drug Interactions

The ingredients in Power Nitro Blood Vessels interact with 409 drugs. Click any drug to see the details.

4 of the 5 ingredients in Power Nitro Blood Vessels interact with drugs. Each result below shows which ingredient is responsible. L-Arginine Stevia Leaf Extract L-Citrulline L-Lysine

Each ingredient & the kinds of drugs it affects

For each ingredient in Power Nitro Blood Vessels with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Arginine9 drug types · 403 drugs

Ace Inhibitors (Aceis)

Theoretically, concomitant use of L-arginine and ACE inhibitors may increase the risk for hypotension and hyperkalemia.
Combining L-arginine with some antihypertensive drugs, especially ACE inhibitors, seems to have additive vasodilating and blood pressure-lowering effects. Furthermore, ACE inhibitors can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ACE inhibitors with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, concomitant use of L-arginine and ARBs may increase the risk of hypotension and hyperkalemia.
L-arginine increases nitric oxide, which causes vasodilation. Combining L-arginine with ARBs seems to increase L-arginine-induced vasodilation. Furthermore, ARBs can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ARBs with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Preliminary research suggests that L-arginine infusions reduce platelet aggregation in humans. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of L-arginine might have additive effects with antidiabetes drugs.
Preliminary clinical research shows that L-arginine decreases blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
L-arginine increases nitric oxide, which causes vasodilation. Clinical evidence shows that L-arginine can reduce blood pressure in some individuals with hypertension. Furthermore, combining L-arginine with some antihypertensive drugs seems to have additive vasodilating and blood pressure-lowering effects.

Likelihood Probable Evidence D
Isoproterenol (Isuprel)

Theoretically, concurrent use of isoproterenol and L-arginine might result in additive effects and hypotension.
Preliminary clinical evidence suggests that L-arginine enhances isoproterenol-induced vasodilation in patients with essential hypertension or a family history of essential hypertension.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically concomitant use of potassium-sparing diuretics with L-arginine may increases the risk of hyperkalemia.
Potassium-sparing diuretics can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and L-arginine might increase the risk for hypotension.
In vivo, concurrent use of L-arginine and sildenafil has resulted in increased vasodilation. Theoretically, concurrent use might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
Testosterone

Theoretically, concomitant use of L-arginine and testosterone might have additive effects.
In clinical research, L-arginine increases the level of testosterone in male patients with erectile dysfunction. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
L-Arginine full monograph & interactions

Stevia Leaf Extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia Leaf Extract full monograph & interactions

L-Citrulline2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline full monograph & interactions

L-Lysine1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D
L-Lysine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Power Nitro Blood Vessels, from the product label.

Dr. Seth's Vitamin Vibrations

See all Dr. Seth's Vitamin Vibrations products
Name
HE Heaven's Energy LLC.
City
Lower Burrell
State
PA
ZipCode
15068
Phone Number
724-334-2225
Pharmacist Counseling Corner

Power Nitro Blood Vessels by Dr. Seth's Vitamin Vibrations: Common Questions

Does Power Nitro Blood Vessels by Dr. Seth's Vitamin Vibrations interact with any medications?
Yes. Based on its ingredients, Power Nitro Blood Vessels has a known interaction with 409 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Power Nitro Blood Vessels contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
L-arginine is rated possibly safe in pregnancy, but L-citrulline, L-lysine, and L-proline data in pregnancy isn't sufficient to rate — there's not enough reliable information. Stevia safety during pregnancy is also not well studied at supplement doses. Talk with your doctor or pharmacist before using this product while pregnant.
What does L-citrulline do?
L-citrulline is an amino acid your body converts to L-arginine, which helps dilate blood vessels and increase blood flow. Research suggests it may help with athletic performance, though evidence for other uses like cardiovascular disease or heart failure is insufficient to rate.
Is lysine in here for cold sores?
Yes — L-lysine is rated possibly effective for cold sores. That said, this product is a multi-ingredient blend aimed at blood vessel function overall, not a single-purpose cold sore treatment.
What are the most common side effects I might notice?
With L-arginine, the most likely ones are stomach upset, bloating, nausea, diarrhea, headache, and flushing. L-citrulline may cause heartburn or stomach discomfort. L-lysine can cause diarrhea and abdominal pain. These tend to be mild and temporary.
Is this safe to use long-term?
Long-term safety for L-arginine and L-citrulline hasn't been fully studied. L-proline supplement safety is also not well established. If you're thinking about regular use, run it by your pharmacist or doctor first.
Why does this have stevia in it?
Stevia leaf extract is a natural sweetener used to flavor the powder. Purified stevia in typical food amounts is generally recognized as safe, though supplement doses haven't been as thoroughly studied.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Power Nitro Blood Vessels label
Go deeper

The Full Monographs Behind Power Nitro Blood Vessels’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

L-arginine

Interacts with 403 drugs

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for blood pressure, erectile dysfunction, and...

Read the full L-arginine monograph → Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Proline

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of collagen, but strong human evidence that...

Read the full Proline monograph → Herb & supplement monograph

Lysine

Interacts with 1 drug

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...

Read the full Lysine monograph → Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Power Nitro Blood Vessels's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 95 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-arginine 66 references
  1. Sapienza MA, Kharitonov SA, Horvath I, et al. Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects. Thorax 1998;53:172-5.
  2. Clarkson P, Adams MR, Powe AJ, et al. Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults. J Clin Invest 1996;97:1989-94. PubMed
  3. Tenenbaum A, Fisman EZ, Motro M. L-arginine: Rediscovery in progress. Cardiology 1998;90:153-9.
  4. Brittenden J, Park KGM, Heys SD, et al. L-Arginine stimulates host defenses in patients with breast cancer. Surgery 1994;115:205-12.
  5. Korting GE, Smith SD, Wheeler MA, et al. A randomized double-blind trial of oral L-arginine for treatment of interstitial cystitis. J Urol 1999;161:558-65. DOI
  6. Rector TS, Bank AJ, Mullen KA, et al. Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure. Circulation 1996;93:2135-41.
  7. Siani A, Pagano E, Iacone R, et al. Blood pressure and metabolic changes during dietary L-arginine supplementation in humans. Am J Hypertens 2000;13:547-51. PubMed
  8. Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
  9. Wallace AW, Tom WL. Interaction of L-arginine and phosphodiesterase inhibitors in vasodilation of the porcine internal mammary artery. Anesth Analg 2000;90:840-6. DOI
  10. Huynh NT, Tayek JA. Oral arginine reduces systemic blood pressure in type 2 diabetes: its potential role in nitric oxide generation. J Am Coll Nutr 2002;21:422-7.. PubMed
  11. Staff AC, Berge L, Haugen G, et al. Dietary supplementation with L-arginine or placebo in women with pre-eclampsia. Acta Obstet Gynecol Scand 2004;83:103-7.
  12. Resnick DJ, Softness B, Murphy AR, et al. Case report of an anaphylactoid reaction to arginine. Ann Allergy Asthma Immunol 2002;88:67-8. PubMed
  13. Anon. Arginine hydrochloride injection (marketed as R-Gene 10). FDA Drug Safety Newsletter 2009;2(2):16-18. Available at: www.fda.gov/Drugs/DrugSafety/DrugSafetyNewsletter/default.htm.
  14. Higashi Y, Oshima T, Sasaki S, et. al. Angiotensin-converting enzyme inhibition, but not calcium antagonism, improves a response of the renal vasculature to L-arginine in patients with essential hypertension. Hypertension. 1998 Jul;32(1):16-24.
  15. Facchinetti, F., Longo, M., Piccinini, F., Neri, I., and Volpe, A. L-arginine infusion reduces blood pressure in preeclamptic women through nitric oxide release. J Soc Gynecol.Investig. 1999;6(4):202-207. DOI
  16. de Gouw, H. W., Verbruggen, M. B., Twiss, I. M., and Sterk, P. J. Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma. Thorax 1999;54(11):1033-1035. PubMed
  17. Komers, R., Komersova, K., Kazdova, L., Ruzickova, J., and Pelikanova, T. Effect of ACE inhibition and angiotensin AT1 receptor blockade on renal and blood pressure response to L-arginine in humans. J Hypertens. 2000;18(1):51-59. PubMed
  18. Cartledge, J. J., Davies, A. M., and Eardley, I. A randomized double-blind placebo-controlled crossover trial of the efficacy of L-arginine in the treatment of interstitial cystitis. BJU.Int. 2000;85(4):421-426.
  19. Sozykin, A. V., Noeva, E. A., Balakhonova, T. V., Pogorelova, O. A., and Men'shikov, M. I. [Effect of L-arginine on platelet aggregation, endothelial function adn exercise tolerance in patients with stable angina pectoris]. Ter.Arkh. 2000;72(8):24-27.
  20. Nagaya, N., Uematsu, M., Oya, H., Sato, N., Sakamaki, F., Kyotani, S., Ueno, K., Nakanishi, N., Yamagishi, M., and Miyatake, K. Short-term oral administration of L-arginine improves hemodynamics and exercise capacity in patients with precapillary pulmona
  21. Stokes, G. S., Barin, E. S., Gilfillan, K. L., and Kaesemeyer, W. H. Interactions of L-arginine, isosorbide mononitrate, and angiotensin II inhibitors on arterial pulse wave. Am J Hypertens. 2003;16(9 Pt 1):719-724.
  22. Park, K. G., Heys, S. D., Blessing, K., Kelly, P., McNurlan, M. A., Eremin, O., and Garlick, P. J. Stimulation of human breast cancers by dietary L-arginine. Clin.Sci.(Lond) 1992;82(4):413-417.
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