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Dietary supplement

Prenatal Wellness Probiotic Mixed Fruit Flavor Ingredients & Drug Interactions

by Culturelle

Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Prenatal Wellness Probiotic Mixed Fruit Flavor is a dietary supplement by Culturelle with 5 active ingredients. Its ingredients are commonly taken for vaginal health support, preventing recurrent bacterial vaginosis, reducing recurrent urinary tract infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus crispatus LBV 88, Lactobacillus gasseri LBV 150N, Lactobacillus jensenii LBV 116. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Prenatal Wellness Probiotic Mixed Fruit Flavor by Culturelle

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “A Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (120 mg) without saying how much of each component you get.

Culturelle Prenatal Wellness Probiotic contains 5 active ingredients, all live bacterial strains: Lactobacillus rhamnosus GG, Lactobacillus crispatus LBV 88, Lactobacillus rhamnosus LBV 96, Lactobacillus gasseri LBV 150N, and Lactobacillus jensenii LBV 116, combined in a proprietary blend. These are probiotics—beneficial bacteria—intended to support vaginal and digestive health during pregnancy.

The tablet also contains inactive ingredients like xylitol, mannitol, microcrystalline cellulose, and natural flavors as fillers and flavor enhancers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive, immune and feminine health support.
  • We looked for evidence on: Bacterial vaginosis, Urinary tract infections (UTIs), Diarrhea, Irritable bowel syndrome (IBS), Vaginal flora balance, Microbiome health — and 2 related terms.
  • The strongest evidence on file: Lactobacillus Crispatus is rated "Possibly Effective" for Bacterial vaginosis (Natural Medicines).
  • Also on file: Lactobacillus Crispatus is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs).
  • Also on file: Lactobacillus Gasseri is rated "Insufficient Reliable Evidence To Rate" for Bacterial vaginosis, Diarrhea, Irritable bowel syndrome (IBS).

The evidence for most of these probiotics is still being built. Lactobacillus crispatus shows possibly effective evidence for bacterial vaginosis, but the data for urinary tract infections and preterm labor is insufficient.

For Lactobacillus gasseri, we don't yet have enough reliable evidence to rate it for any condition, including bacterial vaginosis or diarrhea. Lactobacillus jensenii has no effectiveness ratings in our data.

Talk with your doctor about what this product is meant to do for your pregnancy and whether the current evidence supports your personal health goals.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These live probiotics are generally well tolerated in healthy adults, though safety data is limited and quality varies between products. In rare cases, Lactobacillus crispatus has caused nausea, gas, flatulence, and very rarely a swollen tongue or throat.

Because these are live microorganisms, there is theoretical concern—though very uncommon—that they could cause serious infection in vulnerable patients, including bacteremia, sepsis, or endocarditis; this risk is thought to stem from bacteria moving from their normal locations in the body to places they shouldn't be. During breastfeeding, safety data is limited; speak with your doctor first.

The product label notes pregnancy and lactation information but does not specify the details in our data, so check with your doctor or pharmacist about whether this is right for you during pregnancy or while nursing.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Lactobacillus Crispatus, Lactobacillus Gasseri, Lactobacillus Jensenii.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this probiotic, check with your doctor or pharmacist if you take any antibiotic drugs—they can reduce how well the probiotics work, and you may need to space doses several hours apart. We could not check two of the five active ingredients for other medication interactions, so run your full medication list through our search tool on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic is marketed for prenatal wellness and contains several live Lactobacillus strains. Evidence for most conditions is still developing, and safety data during pregnancy and breastfeeding is limited.

If you're pregnant or nursing, take antibiotics, or have any concerns about starting a probiotic, talk it over with your own doctor or pharmacist before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prenatal Wellness Probiotic Mixed Fruit Flavor, straight from the product label.

Brand Culturelle
Barcode (UPC) 049100401027
Net contents 30 Once Daily Chewable Tablet(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 250636
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses Structure/Function
Intended target group(s) Pregnant Women, Adult Female (18 - 50 Years), Lactating, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prenatal Wellness Probiotic Mixed Fruit Flavor by Culturelle, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
30
UPC/BARCODE
049100401027
IngredientAmount% DV
Calories5 Calories--
Total Carbohydrates1 Gram(s)1%, 1%
Added Sugars0 Gram(s)--
Total Sugars0 Gram(s)--
Sugar Alcohol1 Gram(s)--
Lactobacillus rhamnosus GG0 NP--
Lactobacillus crispatus LBV 880 NP--
Lactobacillus rhamnosus LBV 960 NP--
Lactobacillus gasseri LBV 150N0 NP--
Lactobacillus jensenii LBV 1160 NP--
A Proprietary Probiotic Blend120 mg--

Other ingredients: Xylitol, Mannitol, Microcrystalline Cellulose, Magnesium Stearate, Hydroxypropyl Cellulose, Citric Acid, Natural Flavors, Stearic Acid, Vegetable juice, Malic Acid, Stevia leaf extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Our brand values We’re on a mission to inspire better health & wellness for you & your family. We believe in integrity, so we hold ourselves to the highest standards of truth. We believe in the natural power of your body’s microbiome, & in scientific research & products that will unlock its full potential. We believe in uncompromising quality, safety & proven efficacy. We believe in empowering you to embrace every day with confidence.

The Culturelle Difference

From the most trusted probiotic brand

Safe & gentle Mixed fruit flavor with other natural flavors

Now is one of the most precious times in your life.

For questions, concerns or to report an adverse event, please call (800) 722-3476. www.Culturelle.com Scan to learn more

Based on the 2019 BrandSpark American Shopper Study. Based on the number of Lactobacillus rhamnosus GG clinical studies, as of January 2019. Guaranteed potency through date on box when stored as directed.

Formulation

Naturally Sourced LGG Most Clinically Researched Strain In Children

Guaranteed Purity & Potency

Dairy Gluten Soy Free

Excludes gummy formulas.

Promotes baby's healthy development Supports your digestive, immune & feminine health

Free from Milk Wheat Eggs Tree Nuts Peanuts

Culturelle prenatal wellness probiotic Safe, gentle & proven ingredients to help support you throughout your journey–before, during & after pregnancy. With LGG strain, the most extensively studied probiotic in infants + Unique probiotic blend designed for expecting moms Take as a companion to your prenatal multivitamin Safe and gentle for mom & baby

Meets the FDA’s guidelines for gluten-free.

FDA Statement of Identity

Probiotic Supplement

Brand IP Statement(s)

Culturelle is a trademark of DSM. LGG and LGG logo are trademarks of Chr. Hansen A/S.

Precautions

Allergy friendly

Keep out of reach of children.

Inform a healthcare professional before starting any dietary supplement, particularly if there is a known immune-compromised condition. When first taking a probiotic, your gut microbiome adjusts. You may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your healthcare professional if symptoms continue after two weeks.

Tamper Evident: Product is sealed within a vial. Do not use if any part of the vial is torn, open or damaged.

Not a reduced calorie food.

Suggested/Recommended/Usage/Directions

Directions: For use before, during and after pregnancy, including while breastfeeding. Chew one (1) tablet daily.

Storage

Storage Instructions: Store Culturelle in a cool, dry place away from direct sunlight. Close cap firmly after use.

See for yourself

Prenatal Wellness Probiotic Mixed Fruit Flavor by Culturelle label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Prenatal Wellness Probiotic Mixed Fruit Flavor by Culturelle

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

A Proprietary Probiotic Blend

120 mg per serving

Other (inactive) ingredients: Xylitol, Mannitol, Microcrystalline Cellulose, Magnesium Stearate, Hydroxypropyl Cellulose, Citric Acid, Natural Flavors, Stearic Acid, Vegetable juice, Malic Acid, Stevia leaf extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prenatal Wellness Probiotic Mixed Fruit Flavor by Culturelle Drug Interactions

Want to check YOUR meds against Prenatal Wellness Probiotic Mixed Fruit Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Each ingredient & the kinds of drugs it affects

For each ingredient in Prenatal Wellness Probiotic Mixed Fruit Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus crispatus LBV 881 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus crispatus with antibiotic drugs might decrease the effectiveness of L. crispatus.
Lactobacillus crispatus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. crispatus preparations by at least two hours.

Likelihood Probable Evidence D

Lactobacillus gasseri LBV 150N1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.

Likelihood Probable Evidence D

Lactobacillus jensenii LBV 1161 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus jensenii with antibiotic drugs might decrease the effectiveness of L. jensenii.
Lactobacillus jensenii preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. jensenii preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Prenatal Wellness Probiotic Mixed Fruit Flavor, from the product label.

Culturelle

Name
i-Health, Inc.
Street Address
55 Sebethe Drive
City
Cromwell
State
CT
ZipCode
06416
Phone Number
(800) 722-3476
Web Address
www.culturelle.com
Pharmacist Counseling Corner

Prenatal Wellness Probiotic Mixed Fruit Flavor by Culturelle: Common Questions

Does Prenatal Wellness Probiotic Mixed Fruit Flavor by Culturelle interact with any medications?
Yes. Based on its ingredients, Prenatal Wellness Probiotic Mixed Fruit Flavor has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prenatal Wellness Probiotic Mixed Fruit Flavor contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
The product is labeled for prenatal use, but the safety data in our records doesn't specify what's known about its ingredients during pregnancy. Because you're pregnant, talk with your doctor or midwife before starting—they know your full health picture and can confirm this is right for you.
Can I take this if I'm breastfeeding?
Safety data while breastfeeding is limited for these probiotic strains. Check with your doctor or pharmacist first to see if it's appropriate for you and your baby.
What are probiotics, and why would I take them during pregnancy?
Probiotics are live beneficial bacteria. Some people take them to support digestive and vaginal health. Talk with your doctor about whether this product matches your pregnancy health goals, since evidence for several of these strains is still building.
What if I'm on antibiotics—should I skip this probiotic?
Not necessarily skip it, but space them out. Antibiotics can kill the live organisms in the probiotic, making it less effective. Ask your pharmacist how many hours apart to take them—typically a few hours works well.
Are there any side effects?
In rare cases, these probiotics have caused nausea, gas, flatulence, or very rarely a swollen tongue. Because they're live organisms, there's also a theoretical (though very uncommon) risk of infection in vulnerable patients. If you have any unusual symptoms or concerns, talk with your doctor.
Does it contain any allergens or fillers I should know about?
The inactive ingredients include xylitol, mannitol, cellulose, and natural flavors. There are no major allergens listed, but check the full ingredient list if you have sensitivities to any of these items.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Prenatal Wellness Probiotic Mixed Fruit Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prenatal Wellness Probiotic Mixed Fruit Flavor label
Sources

Sources & How We Checked

Prenatal Wellness Probiotic Mixed Fruit Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Crispatus 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  7. DI Pierro F, Criscuolo AA, Dei Giudici A, et al. Oral administration of Lactobacillus crispatus M247 to papillomavirus-infected women: results of a preliminary, uncontrolled, open trial. Minerva Obstet Gynecol 2021;73(5):621-631. PubMed
  8. DE Leo V, Lazzeri E, Governini L, et al. Vaginal colonization of women after oral administration of Lactobacillus crispatus strain NTCVAG04 from the human microbiota. Minerva Obstet Gynecol 2022. PubMed
  9. Dellino M, Cascardi E, Laganà AS, et al. Lactobacillus crispatus M247 oral administration: Is it really an effective strategy in the management of papillomavirus-infected women?. Infect Agent Cancer 2022;17(1):53. PubMed

See these in context on the Lactobacillus Crispatus monograph →

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
  3. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  4. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  5. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  6. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  7. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  8. Ramos-Coria D, Canto-Losa J, Carrillo-Vázquez D, Carbajal-Morelos L, Estrada-León R, Corona-Rodarte E. Lactobacillus gasseri liver abscess and bacteremia: a case report. BMC Infect Dis 2021;21(1):518. PubMed
  9. Elikowski W, Malek-Elikowska M, Lisiecka M, Bodora A, Wisniewska K, Oko-Sarnowska Z. Lactobacillus gasseri endocarditis on the aortic valve bioprosthesis - a case report. Pol Merkur Lekarski 2017;43(257):220-223.
  10. Esquibel A, Dababneh AS, Palraj BR. Lactobacillus gasseri causing bilateral empyema. Case Rep Infect Dis 2017;2017:4895619.
  11. Tleyjeh IM, Routh J, Qutub MO, Lischer G, Liang KV, Baddour LM. Lactobacillus gasseri causing Fournier's gangrene. Scand J Infect Dis 2004;36(6-7):501-3. PubMed
  12. Dickgiesser U, Weiss N, Fritsche D. Lactobacillus gasseri as the cause of septic urinary infection. Infection 1984;12(1):14-6. PubMed

See these in context on the Lactobacillus Gasseri monograph →

Lactobacillus Jensenii 6 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.

See these in context on the Lactobacillus Jensenii monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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