Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Probiotic Advantage Bifido Beadlet 50+ Ingredients & Drug Interactions

by Dr. David Williams

Other (e.g. Tea Bag) Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Probiotic Advantage Bifido Beadlet 50+ is a dietary supplement by Dr. David Williams with 1 active ingredient. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Bifido Beadlet 50+ Blend (Non-Nutrient Non-Botanical). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Probiotic Advantage Bifido Beadlet 50+ by Dr. David Williams

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Probiotic Bifido Beadlet 50+ Blend (Non-Nutrient Non-Botanical)” is a proprietary blend — the label doesn't break down how much of each component you get.

This product contains 6 active probiotic ingredients — strains of Lactobacillus and Bifidobacterium bacteria — each chosen for potential digestive and immune support. The ones we have data for are B. longum BB-536, L. acidophilus NCFM, and B. infantis M-63; the others are L. plantarum Lp-115, L. rhamnosus Lr-32, and B. lactis Bl-04.

It also contains inactive ingredients including vegetable oil, gelatin, glycerin, soy lecithin, and pectin, which serve as fillers and coating materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive balance and regularity support.
  • We looked for evidence on: Antibiotic-associated diarrhea, Constipation, Diarrhea, Irritable bowel syndrome (IBS), Lactose intolerance, bloating — and 2 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Radiation-induced diarrhea, Lactose intolerance, Rotaviral diarrhea, and more.

The evidence is mixed. L. acidophilus NCFM shows possibly effective ratings for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis — meaning some research supports its use for these purposes.

For B. longum BB-536, the data we hold shows insufficient evidence to rate it for age-related cognitive decline, hay fever, antibiotic-associated diarrhea, generalized anxiety, asthma, and athletic performance. The evidence on the other strains in this blend isn't established in the data we have.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Longum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both B. longum and L. acidophilus are generally well tolerated in healthy people, though safety data are limited — talk with your doctor before use, especially if you're seriously ill or immune-compromised. Rare gastrointestinal side effects have been reported with both, including abdominal discomfort, bloating, flatulence, and constipation.

Very rarely, these bacteria have caused serious infections (bacteremia or sepsis) in critically ill patients, preterm infants, and those with severe immune problems. Lactobacillus acidophilus is rated possibly safe in pregnancy; for lactation, safety data aren't on file.

Bifidobacterium longum is rated possibly safe in both pregnancy and lactation, though data are limited — check with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Longum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Longum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check all your antibiotics before you start this product — they can interfere with how well the probiotics work if taken at the same time. Your doctor or pharmacist can tell you how to space them apart.

No other interactions are documented in our data for the ingredients we could check, but we hold no information on three of the six bacterial strains, so confirm your full medication list with your own healthcare provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic blend may help if you're dealing with IBS, antibiotic-associated diarrhea, or certain bacterial infections, though evidence varies by strain. The main caution is timing it right with antibiotics — they can interfere with each other.

If you're seriously ill, immune-compromised, or pregnant or breastfeeding, talk with your doctor or pharmacist before starting; the same goes if you take any prescription medication — use the interaction checker below to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Probiotic Advantage Bifido Beadlet 50+, straight from the product label.

Brand Dr. David Williams
Barcode (UPC) 678829241623
Net contents 90 Once-Daily Beadlet(s)
Market status On market
Date entered into DSLD Jun 24, 2016
DSLD ID 60919
Product type Non-nutrient/non-botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Seniors/Mature (>50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Probiotic Advantage Bifido Beadlet 50+ by Dr. David Williams, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Beadlet(s)
Maximum serving Sizes:
1 Beadlet(s)
Servings per container
90
UPC/BARCODE
678829241623
IngredientAmount% DV
L. plantarum Lp-1150 NP--
L. rhamnosus Lr-320 NP--
B. longum BB-5360 NP--
L. acidophilus NCFM0 NP--
B. lactis Bl-040 NP--
Probiotic Bifido Beadlet 50+ Blend (Non-Nutrient Non-Botanical)0 NP--
B. infantis M-630 NP--

Other ingredients: Vegetable Oil, Gelatin, Glycerin, Soy Lecithin, Pectin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

High Bifidobacteria probiotic with Advanced Bead-Lock Technology restores digestive balance after age 50

Probiotic Advantage Bifido Beadlet 50+ contains more Bifidobacteria than Lactobacillus to help replenish naturally declining Bifidobacteria levels and support regularity and digestive balance.

Just 1 daily, easy-to-swallow probiotic beadlet guarantees the delivery of 2 billion live Bifidobacteria and Lactobacillus cultures with 6 scientifically studied strains that provide full intestinal coverage for maximum digestive support.

Contains: Soy, Milk

FDA Statement of Identity

Dietary Supplement

General Statements

People over the age of 50 begin to have a decline in Bifidobacteria.

When taken daily, this formula promotes overall digestion, supports regularity, relieves occasional constipation, gas, and bloating, and supports immune health.

Unconditionally guaranteed for purity and labeled potency.

Beadlet actual size:

This product contains natural ingredients, color variations are normal.

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Brand IP Statement(s)

Probiotic Advantage Bifido Beadlet 50+ uses Advanced Bead-Lock Technology to ensure that 2 billion live probiotics are protected to survive stomach acid and reach your intestines, where they are needed.

Searching the world for better health

Storage

Store in a cool, dry place. Seal pouch after each use. No refrigeration necessary.

Suggested/Recommended/Usage/Directions

Doctor’s suggested use: Take 1 beadlet daily prior to a meal. Do not chew or crush.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

SKU: WBD 02 D31000, 2016 R-1

Precautions

Contains: Soy, Milk

Note: Pregnant or lactating women should consult a health care professional before taking this product.

Keep out of reach of children.

See for yourself

Probiotic Advantage Bifido Beadlet 50+ by Dr. David Williams label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Probiotic Advantage Bifido Beadlet 50+ by Dr. David Williams

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Beadlet(s) Dosage formOther (e.g. Tea Bag) Servings per container90 Amounts shown are per serving.

0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic Bifido Beadlet 50+ Blend (Non-Nutrient Non-Botanical) monograph & interactions

Other (inactive) ingredients: Vegetable Oil, Gelatin, Glycerin, Soy Lecithin, Pectin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Probiotic Advantage Bifido Beadlet 50+ by Dr. David Williams Drug Interactions

Want to check YOUR meds against Probiotic Advantage Bifido Beadlet 50+?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Probiotic Advantage Bifido Beadlet 50+ with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Probiotic Bifido Beadlet 50+ Blend (Non-Nutrient Non-Botanical)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Probiotic Advantage Bifido Beadlet 50+, from the product label.

Dr. David Williams

See all Dr. David Williams products
Name
Healthy Directions
City
Bethesda
State
MD
ZipCode
20817
Web Address
healthydirections.com
Pharmacist Counseling Corner

Probiotic Advantage Bifido Beadlet 50+ by Dr. David Williams: Common Questions

Does Probiotic Advantage Bifido Beadlet 50+ by Dr. David Williams interact with any medications?
Yes. Based on its ingredients, Probiotic Advantage Bifido Beadlet 50+ has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Probiotic Advantage Bifido Beadlet 50+ contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm on antibiotics?
Not at the same time. Antibiotics kill bacteria — including the live probiotics in this product — so they can make each other less effective. Separate them by a few hours; your doctor or pharmacist can tell you the best timing for your specific antibiotic.
Is this safe during pregnancy or while breastfeeding?
Lactobacillus acidophilus is rated possibly safe in pregnancy. Bifidobacterium longum is rated possibly safe in both pregnancy and lactation, though safety data are limited. Since you're making a decision for you and your baby, talk with your doctor or pharmacist about whether this product is right for you.
What side effects might I experience?
Most people tolerate it well. Rarely, people report mild gastrointestinal effects like bloating, gas, abdominal discomfort, or constipation. One person in a trial reported a dry cough. Serious infections from these probiotics are extremely rare and occur mainly in critically ill or immune-compromised patients.
Does this product help with antibiotic-associated diarrhea?
Lactobacillus acidophilus NCFM in this blend is rated possibly effective for antibiotic-associated diarrhea. The evidence on the other strains isn't established in the data we hold. Talk with your doctor about whether this product is right for your situation.
What are these bacterial strains for?
Probiotics are live beneficial bacteria meant to support digestive health and the gut microbiome. L. acidophilus may help with IBS, certain bacterial infections, and diarrhea. The data on B. longum and the other strains for specific conditions isn't established enough to make claims.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Probiotic Advantage Bifido Beadlet 50+ is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Probiotic Advantage Bifido Beadlet 50+ label
Sources

Sources & How We Checked

Probiotic Advantage Bifido Beadlet 50+'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 36 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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