Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors is a dietary supplement by Schiff Digestive Advantage with 2 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,083 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, BC30 Bacillus coagulans GBI-30, 6086. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors by Schiff Digestive Advantage
Ask about any prescription or over-the-counter medication and we check it for interactions with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors by Schiff Digestive Advantage — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors by Schiff Digestive Advantage
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: BC30 Bacillus coagulans GBI-30, 6086, a live probiotic bacterium. The inactive ingredients include prebiotic fiber in the form of fructooligosaccharides (which feed beneficial bacteria), plus sugar, corn syrup, gelatin, and various acids and flavorings to make the gummy palatable.
Does it work?
Strong evidence
Bacillus coagulans has been rated Possibly Effective for constipation and for irritable bowel syndrome (IBS). For antibiotic-associated diarrhea, athletic performance, cancer prevention, and fatty liver disease, the evidence we hold is insufficient to rate whether it works.
That doesn't mean it doesn't help with those conditions — just that reliable studies aren't available yet in our data.
How safe is it?
Well-documented data
Bacillus coagulans is generally well tolerated in healthy adults, though the evidence and quality of probiotic products do vary. There isn't enough reliable safety data to be fully certain, so it's worth talking to your doctor or pharmacist before you start — especially if you're severely ill, immunocompromised, have a central venous catheter, or are a preterm infant.
In those groups, reports of serious infection (bacteremia and sepsis) from probiotic products exist, though they're rare in otherwise healthy people with a working immune system. Pregnancy and lactation safety information for this ingredient is not on file.
Meds to double-check
Moderate interaction found
Antibiotics are the medication type you need to check before taking this product. They can reduce the probiotic's effectiveness if taken at the same time — separate the two by a few hours.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you have constipation or IBS and want to try a probiotic, Bacillus coagulans is a reasonable option. The main thing to watch is spacing it apart from any antibiotics you take, since antibiotics can kill the live organisms.
Check your exact medications with your doctor or pharmacist before starting, especially if you have any immune system concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors, straight from the product label.
| Brand | Schiff Digestive Advantage |
|---|---|
| Barcode (UPC) | 020525183613 |
| Net contents | 65 Gummy(ies) |
| Market status | On market |
| Date entered into DSLD | Dec 26, 2020 |
| DSLD ID | 240985 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Gummy Or Jelly |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors by Schiff Digestive Advantage, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s) | -- |
| Total Carbohydrates | 6 Gram(s) | 2% |
| Dietary Fiber | 3 Gram(s) | 9% |
| Total Sugars | 2 Gram(s) | -- |
| BC30 Bacillus coagulans GBI-30, 6086 | 10.66 mg | -- |
Other ingredients: Fructooligosaccharides, Sugar, Corn Syrup, Water, Gelatin, Lactic Acid, Citric Acid, Natural Flavors, Colors, Pectin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Take the inside advantage #1 probiotic gummy brand Infused with BC30 Great tasting probiotic gummies, easy to fit into your daily routine
Our probiotic is protected with a natural protein shell to deliver more live good bacteria to your gut, and works to support overall digestive health, helps lessen minor abdominal discomfort and occasional bloating Prebiotic fiber feeds the natural good bacteria in your gut Helps support immune health and digestive balance Purity Freshness Potency
Probiotic survives stomach acid 100x better
Prebiotics help support the growth of healthy bacteria
Gluten-free
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Based on median survivability of Digestive Advantage probiotic BC10 vs. leading yogurt in a simulated gastric environment. Based on unit sales L52W through 4/25/20. Schiff since 1936
Formula
A unique blend of probiotic & prebiotic
Great tasting natural fruit flavors
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Adults and children 4 years of age and older: Chew two (2) gummies daily. Not for children under 3 years of age due to the risk of choking. Chew thoroughly before swallowing.
Precautions
Not for children under 3 years of age due to the risk of choking.
Contains soy.
If pregnant, breastfeeding, on medication, or are immunocompromised, consult your physician before using this product.
Keep out of reach of children. Always consult your pediatrician before giving your child dietary supplements.
Protected with a tamper evident seal. Do not use if seal under cap is broken or missing.
Brand IP Statement(s)
2020 RB Health Health Hygiene Home Patents: www. rb.com/patents
Storage
Store in a cool, dry place with lid tightly closed.
Seals/Symbols
Schiff Quality Guarantee
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors by Schiff Digestive Advantage label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors by Schiff Digestive Advantage
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container32 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsBC30 Bacillus coagulans GBI-30, 6086
Interacts with182 drugs
Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...
BC30 Bacillus coagulans GBI-30, 6086 monograph & interactionsOther (inactive) ingredients: Fructooligosaccharides, Sugar, Corn Syrup, Water, Gelatin, Lactic Acid, Citric Acid, Natural Flavors, Colors, Pectin. These complete the product’s ingredient list but are not active constituents.
Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors by Schiff Digestive Advantage Drug Interactions
HelloPharmacist Interaction Report
Schiff Digestive Advantage Daily Probiotics + Prebiotic Fiber Support contains BC30 Bacillus coagulans, a live probiotic organism that has a documented Moderate interaction with antibiotics.
When you take antibiotics at the same time as this probiotic, the antibiotics may kill a significant number of the live organisms in the product, potentially reducing how well the probiotic works for you.
Read the full breakdown — every affected drug type, severity by severity
Additionally, the interaction is preventable: you can separate when you take antibiotics and this probiotic by a few hours. This gives the probiotic time to establish itself before the antibiotic dose arrives.
Altogether, these interactions span 182 individual medications.
To see whether your specific antibiotic is one to space out, use the interaction checker below and enter your medication name.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors interact with 2,083 drugs. Click any drug to see the details.
2 of the 2 ingredients in Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber BC30 Bacillus coagulans GBI-30, 6086
Alogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Metformin interactionAmikacinAmikin, Arikayce
How Amikacin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Amikacin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Amoxicillin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Amoxicillin Veterinary interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Amoxicillin, Clavulanate Potassium interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Amphotericin, Tetracycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Ampicillin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Azithromycin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Bacampicillin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Benznidazole interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Canagliflozin, Metformin Hydrochloride interactionCapreomycinCapastat
How Capreomycin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Capreomycin interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberCarbamazepine (tegretol), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Read the full Dietary Fiber + Carbamazepine interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Carbenicillin Indanyl Sodium interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Cefaclor interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Cefadroxil interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Cefdinir interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Cefditoren Pivoxil interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 1 ingredient. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors — through 2 ingredients. Tap an ingredient for the detail:
Bc30 Bacillus Coagulans Gbi-30, 6086Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Bc30 Bacillus Coagulans Gbi-30, 6086 + Cefixime interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefixime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
BC30 Bacillus coagulans GBI-30, 6086
Antibiotic Drugs
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.
Brand information
Manufacturer and brand details for Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors, from the product label.
Schiff Digestive Advantage
See all Schiff Digestive Advantage products- Name
- RB Health (US) LLC
- City
- Parsippany
- State
- NJ
- ZipCode
- 07054-0224
- Phone Number
- 1-800-526-6251
- Web Address
- www.digestiveadvantage.com
Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors by Schiff Digestive Advantage: Common Questions
Does Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors by Schiff Digestive Advantage interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this probiotic actually help with IBS or constipation?
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Are there any side effects I should know about?
Is it safe to take during pregnancy or while breastfeeding?
Does it actually contain prebiotics, or is the name just marketing?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographBacillus Coagulans
Interacts with 182 drugsBacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...
Read the full Bacillus Coagulans monograph →Sources & How We Checked
Daily Probiotics + Prebiotic Fiber Support Natural Fruit Flavors's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 38 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Bacillus Coagulans 20 references
- Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
- Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
- Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
- Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
- Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
- Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
- MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
- Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
- De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
- Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
- Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
- Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
- Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
- Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
- Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
- Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC