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Dietary supplement

Prosta SPET-085 Ingredients & Drug Interactions

by PL Progressive Laboratories

Prosta SPET-085 label
See full label image
Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prosta SPET-085 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Prosta SPET-085 is a dietary supplement by PL Progressive Laboratories with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary problems, hair loss.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are SPET-085. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Prosta SPET-085 by PL Progressive Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Prosta SPET-085 by PL Progressive Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Prosta SPET-085 by PL Progressive Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: saw palmetto (SPET-085). Saw palmetto is a plant extract traditionally used for prostate and urinary symptoms.

The capsule also contains inactive ingredients — sesame seed oil, vegetable cellulose, beeswax, and mixed tocopherols — which help form and preserve the supplement.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: prostate health support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Non-neurogenic lower urinary tract symptoms (LUTS), Prostatitis, Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), urinary symptoms, prostate function.
  • The closest evidence on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Saw Palmetto is rated "Insufficient Reliable Evidence To Rate" for Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostatitis, Non-neurogenic lower urinary tract symptoms (LUTS).

The evidence on saw palmetto is mixed. For transurethral resection of the prostate (TURP), a surgical procedure for prostate removal, it's possibly effective.

For benign prostatic hyperplasia (BPH) — enlargement of the prostate gland — the evidence suggests it may not be effective. For chronic bronchitis, male-pattern baldness, and lower urinary tract symptoms, the evidence isn't established well enough to rate.

The evidence, ingredient by ingredient Saw Palmetto

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Saw palmetto is generally well tolerated in adults, with mild, infrequent side effects. The most common ones are abdominal pain, constipation, decreased libido, diarrhea, dizziness, fatigue, headache, nausea, and sinus inflammation.

Rarely, skin reactions like blisters and sores have been reported, as well as heart issues such as high blood pressure, rapid heartbeat, chest pain, and irregular heartbeat — though these are uncommon. You should avoid this product during pregnancy and while breastfeeding.

The safety data is insufficient, and saw palmetto's hormone-related effects raise concern.

Side effects, ingredient by ingredient Saw Palmetto

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Saw Palmetto.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you're on blood thinners or antiplatelet drugs (like aspirin, warfarin, or clopidogrel) — saw palmetto may increase bleeding risk. Also double-check if you're taking birth control pills or estrogen therapy, since saw palmetto may reduce their effectiveness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Saw palmetto may help with certain prostate procedures, though its benefits for enlarged prostate itself aren't clear. If you take blood thinners, birth control, or hormone therapy, talk with your doctor or pharmacist before starting — saw palmetto can interfere with how they work.

Stop and contact your healthcare provider if you notice unusual bleeding, chest pain, or an irregular heartbeat.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prosta SPET-085, straight from the product label.

Brand PL Progressive Laboratories
Barcode (UPC) 351821010274
Net contents 60 Liquid Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 263145
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prosta SPET-085 by PL Progressive Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Liquid Vegetable Capsule(s)
Maximum serving Sizes:
2 Liquid Vegetable Capsule(s)
Servings per container
30
UPC/BARCODE
351821010274
IngredientAmount% DV
SPET-085640 mg--

Other ingredients: Sesame seed Oil, Vegetable Cellulose, Beeswax, mixed Tocopherols

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one to two liquid vegetable capsules daily or as directed by a health care professional.

Precautions

Sold only for dispensing by a licensed health professional.

Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing.

Keep out of the reach of children.

Brand IP Statement(s)

SPET-085 is a trademark of Euromed USA Inc., Corp. Licaps is a registered trademark of Capsugel.

Science + therapeutic potency = results PL Since 1972 Progressive Laboratories

Formulation

Progressive Laboratories manufactured this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)

Seals/Symbols

GMP 3rd party confirmed compliant

FDA Statement of Identity

Dietary Supplement

Formula

Licaps Visible - Liquid - Capsule

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prosta SPET-085 by PL Progressive Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prosta SPET-085 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prosta SPET-085 by PL Progressive Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Liquid Vegetable Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

SPET-085

Interacts with
174 drugs
640 mg per serving Form: Fatty Acids, Saw Palmetto Lipid Sterolic Extract

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...

SPET-085 monograph & interactions

Other (inactive) ingredients: Sesame seed Oil, Vegetable Cellulose, Beeswax, Mixed Tocopherols. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prosta SPET-085 by PL Progressive Laboratories Drug Interactions

Want to check YOUR meds against Prosta SPET-085?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

SPET-085 174

Individual Drug Interactions

The ingredients in Prosta SPET-085 interact with 174 drugs. Click any drug to see the details.

1 of the 1 ingredient in Prosta SPET-085 interact with drugs. Each result below shows which ingredient is responsible. SPET-085

Each ingredient & the kinds of drugs it affects

For each ingredient in Prosta SPET-085 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

SPET-0853 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
SPET-085 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prosta SPET-085, from the product label.

PL Progressive Laboratories

See all PL Progressive Laboratories products
Name
Progressive Laboratories, Inc.
City
Irving
State
Texas
ZipCode
75038
Phone Number
1-800-527-9512
Pharmacist Counseling Corner

Prosta SPET-085 by PL Progressive Laboratories: Common Questions

Does Prosta SPET-085 by PL Progressive Laboratories interact with any medications?
Yes. Based on its ingredients, Prosta SPET-085 has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prosta SPET-085 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is SPET-085, and what's it supposed to do?
SPET-085 is saw palmetto, an extract from a plant traditionally used for prostate and urinary health. Evidence suggests it may help with prostate removal procedures, but doesn't appear to work well for an enlarged prostate gland.
Can I take this if I'm on birth control?
No — saw palmetto may reduce how well birth control pills work because it can interfere with estrogen. Talk to your doctor or pharmacist about whether this product is right for you if you're on contraceptives.
Is this safe to take during pregnancy or while breastfeeding?
No. The safety data is insufficient and there's concern about hormone effects, so avoid this product if you're pregnant or breastfeeding. Talk with your doctor if you have questions.
What are the most common side effects?
Saw palmetto is generally well tolerated, but some people report abdominal pain, constipation, diarrhea, dizziness, fatigue, headache, or nausea. These are mild and usually reversible.
Can I take this with aspirin or other blood thinners?
Probably not — saw palmetto may increase bleeding risk when combined with blood thinners or antiplatelet drugs. Check with your doctor or pharmacist before taking them together.
Does this product contain any fillers or just the active ingredient?
It contains saw palmetto as the active ingredient, plus inactive ingredients like sesame oil, vegetable cellulose, beeswax, and tocopherols to form the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Prosta SPET-085 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prosta SPET-085 label
Go deeper

The Full Monographs Behind Prosta SPET-085’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph →
Sources

Sources & How We Checked

Prosta SPET-085's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Saw Palmetto 22 references
  1. Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
  2. Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
  3. Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
  4. Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
  5. Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
  6. Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
  7. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  8. Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
  9. Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
  10. Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
  11. Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
  12. Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
  13. Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
  14. Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
  15. Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
  16. Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
  17. Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
  18. Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
  19. Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
  20. Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
  21. Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
  22. Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed

See these in context on the Saw Palmetto monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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