Interactions on record — worth a quick check against your medications. Based on 3 of 10 ingredients. Check your meds →
Dietary supplement

ProstaCare Ingredients & Drug Interactions

by Himalaya

ProstaCare label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ProstaCare against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ProstaCare is a dietary supplement by Himalaya with 10 active ingredients. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 266 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tribulus, Shatavari. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against ProstaCare by Himalaya

Ask about any prescription or over-the-counter medication and we check it for interactions with ProstaCare by Himalaya — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of ProstaCare by Himalaya

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Proprietary Herbal Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Himalaya ProstaCare contains 10 ingredients, 6 of which are active botanicals. The two most prominent are tribulus and shatavari (also called asparagus racemosus), each present as both whole plant and extract forms.

Three-Leaf Caper and Betelnut Palm appear twice each in extract and whole-plant versions. A proprietary herbal blend and bonduc (divi-divi) round out the formula.

The capsule itself is made from plant-based cellulose.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support normal urinary flow and prostate health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Male infertility, Sexual dysfunction, Erectile dysfunction (ED), Sexual desire, Lower urinary tract symptoms — and 2 related terms.
  • The strongest evidence on file: Tribulus is rated "Possibly Effective" for Sexual dysfunction (Natural Medicines).
  • Also on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH), Erectile dysfunction (ED), Male infertility.
  • Also on file: Asparagus Racemosus is rated "Insufficient Reliable Evidence To Rate" for Sexual desire.

The evidence for this product is limited. Tribulus is rated possibly effective for sexual dysfunction, but its use for athletic performance is considered possibly ineffective, and evidence for benign prostatic hyperplasia (enlarged prostate) is too thin to rate.

Shatavari, Three-Leaf Caper, and Bonduc all carry insufficient evidence ratings — meaning the research either doesn't exist or isn't strong enough to draw conclusions about whether they work for their traditional uses like muscle strength, sexual desire, or various respiratory and parasitic conditions. If prostate support is your goal, the data doesn't establish that this formula delivers it.

The evidence, ingredient by ingredient Tribulus Asparagus Racemosus Divi-divi

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term, tribulus and shatavari are generally well tolerated in healthy adults, but long-term safety data are sparse. Rare serious effects from tribulus include liver and kidney injury, seizures, and painful erection with sexual dysfunction; extremely high doses (like 2 liters of tribulus water daily) have caused weakness, seizures, liver inflammation, and acute kidney injury.

Stomach upset — cramping, nausea, vomiting, diarrhea — can occur, though one study found rates similar to placebo. Bonduc and Betelnut Palm have little to no human safety data.

Avoid this product during pregnancy: tribulus may affect hormones and safety is not established, and shatavari, bonduc, and betelnut safety in pregnancy aren't well studied. Breastfeeding is also not recommended because reliable safety data are lacking for all these ingredients.

Side effects, ingredient by ingredient Tribulus Asparagus Racemosus Divi-divi

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Tribulus, Asparagus Racemosus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 266 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against these types before taking ProstaCare: blood pressure drugs (antihypertensive medications) — tribulus may lower blood pressure further; diabetes medications — tribulus may lower blood sugar; lithium — both tribulus and shatavari may raise lithium levels; and water pills (diuretics) — shatavari may increase their effect. No interactions are documented for the other ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

ProstaCare is a multi-herb formula that targets prostate and sexual health, but evidence that it works for those goals is weak or absent. If you take blood pressure drugs, diabetes medications, lithium, or water pills, check with your own doctor or pharmacist before starting — interactions are possible.

Pregnant or nursing? Skip it and talk it over with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ProstaCare, straight from the product label.

Brand Himalaya
Barcode (UPC) 605069010115
Net contents 240 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 80589
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ProstaCare by Himalaya, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
120
UPC/BARCODE
605069010115
IngredientAmount% DV
Tribulus0 NP--
Proprietary Herbal Blend0 NP--
Shatavari0 NP--
Tribulus extract0 NP--
Shatavari extract0 NP--
Three-Leaf Caper0 NP--
Bonduc0 NP--
Betelnut Palm0 NP--
Bonduc extract0 NP--
Betelnut Palm extract0 NP--
Three-Leaf Caper extract0 NP--

Other ingredients: Plant Based Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Ayurveda has spoken for thousands of years about natural, age-related changes occurring in men and discovered a category of plants that provide assistance in the transition.

Featured Herbs On Front: Tribulus (aerial parts), Bonduc (seeds and pods) & Shatavari (aerial patrs)

Contains: Tree nuts

Brand IP Statement(s)

The urinary system is sensitive to aging, but the plants in ProstaCare, like Tribulus and Bonduc, add tone to the urinary canal and associated organs to support normal flow and elimination of urine.

Formulation

Gluten free

Vegan friendly

Wheat Corn Soy Dairy

No ingredients of animal origin

Non-GMO Gluten free

General Statements

cGMP

Our cartons are made from 100% recycled fibers, including 40% post-consumer material. Our glass bottles contain at least 48% recycled content.

Happiness through wellness

Crafting traditional medicines based on Ayurveda, a 5,000 year old science that believes the journey back to wholeness begins with nurturing the capacity for joy.

Trusting the gifts of nature and the irreplaceable relationship between the plant and its native soil for consistent healing properties.

Contributing to the wellness of the earth by teaching our family of farmers to grow native plants sustainably on their land and reduce the demand on the local environment.

Building communities by advocating women in farming, protecting fair prices, providing maternal health, sponsoring clinical services and offering school wellness programs.

Believing that if wellness is the path to happiness, we must contribute to the wellness of all things. Wellness of people, wellness of the environment, wellness of our communities.

Family owned for more than 85 years

Since 1930

For healthy urine flow & elimination Supports prostate & urinary tract health

2 month supply

Mfg. Lic. No. AUS-83

Product of India

General

HUS-5033349

Seals/Symbols

Non GMO Project Verified nongmoproject.org

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Recommended Use: Adults take 2 capsules twice daily with meals.

Precautions

Contains: Tree nuts

Caution: As with any supplement, consult a healthcare practitioner before use if you are pregnant, nursing, taking medication, have a medical condition or are planning any medical procedure.

Discontinue use and consult a healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ProstaCare by Himalaya label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ProstaCare label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ProstaCare by Himalaya

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Herbal Blend

0 NP per serving

Other (inactive) ingredients: Plant Based Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

ProstaCare by Himalaya Drug Interactions

Want to check YOUR meds against ProstaCare?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
266Drugs
266 Moderate

Ingredients driving the most interactions

Tribulus 259
Shatavari 76

Individual Drug Interactions

The ingredients in ProstaCare interact with 266 drugs. Click any drug to see the details.

2 of the 10 ingredients in ProstaCare interact with drugs. Each result below shows which ingredient is responsible. Tribulus Shatavari

Each ingredient & the kinds of drugs it affects

For each ingredient in ProstaCare with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Tribulus3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Tribulus full monograph & interactions

Shatavari2 drug types · 76 drugs

Diuretic Drugs

Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus racemosus root has diuretic effects when used in high doses. This effect has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, Asparagus racemosus root could reduce excretion and increase levels of lithium.
Animal research suggests that Asparagus racemosus root has diuretic properties when used in high doses. Therefore, it might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Shatavari full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ProstaCare, from the product label.

Himalaya

See all Himalaya products
Name
The Himalaya Drug Company
City
Makali
State
Bangalore
ZipCode
562 162
Pharmacist Counseling Corner

ProstaCare by Himalaya: Common Questions

Does ProstaCare by Himalaya interact with any medications?
Yes. Based on its ingredients, ProstaCare has a known interaction with 266 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ProstaCare contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does ProstaCare actually work for prostate health?
The evidence doesn't support it. Tribulus is rated possibly effective for sexual dysfunction, but we don't have reliable evidence that it or the other ingredients in this formula improve benign prostatic hyperplasia or prostate health specifically.
Can I take this while I'm pregnant or breastfeeding?
No. Tribulus may affect hormones and isn't safe in pregnancy, and shatavari, bonduc, and betelnut safety in pregnancy and nursing aren't established. Talk with your doctor before taking this during either time.
What are the side effects I should watch for?
Most people tolerate it without trouble, but gastrointestinal complaints like cramping, nausea, vomiting, or diarrhea can happen — though one study found these rates matched placebo. Serious effects are rare but include liver and kidney injury and seizures. Very high intakes have caused weakness and organ damage.
Is this safe to take long-term?
Tribulus and shatavari are well tolerated short-term in healthy adults, but long-term safety data are limited. We don't have enough information to say whether it's safe to use continuously over months or years.
What's tribulus and what is it supposed to do?
Tribulus is a plant used traditionally for sexual function and athletic performance. Research supports it as possibly effective for sexual dysfunction, but it hasn't proven useful for athletic performance, and the evidence for prostate conditions is too weak to judge.
Will this interfere with my blood pressure or diabetes medication?
Possibly. Tribulus can lower blood pressure and blood sugar, so combining it with your medications might cause your pressure to drop too far or your blood sugar to fall too low. Check with your own doctor or pharmacist before adding it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ProstaCare is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ProstaCare label
Go deeper

The Full Monographs Behind ProstaCare’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph → Herb & supplement monograph

Asparagus Racemosus

Interacts with 76 drugs

Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limi...

Read the full Asparagus Racemosus monograph → Herb & supplement monograph

Divi-divi

Divi-divi is a tropical tree whose tannin-rich seed pods have long been used in leather tanning and in traditional folk remedies, mostly as an astringent. There is very little modern human r...

Read the full Divi-divi monograph →
Sources

Sources & How We Checked

ProstaCare's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Asparagus Racemosus 1 reference
  1. Satish Kumar MC, Udupa AL, Sammodavardhana K, Rathnakar UP, Shvetha U, Kodancha GP. Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd in rats. West Indian Med J. 2010;59(1):3-6.

See these in context on the Asparagus Racemosus monograph →

Divi-divi 1 reference
  1. Tannins — MedlinePlus / NIH Source

See these in context on the Divi-divi monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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