Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Prostaid Saw Palmetto Herbal Complex Ingredients & Drug Interactions

by Nature's Truth

Prostaid Saw Palmetto Herbal Complex label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prostaid Saw Palmetto Herbal Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Prostaid Saw Palmetto Herbal Complex is a dietary supplement by Nature's Truth with 4 active ingredients. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 336 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saw Palmetto, Stinging Nettle, Lycopene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Prostaid Saw Palmetto Herbal Complex by Nature's Truth

Ask about any prescription or over-the-counter medication and we check it for interactions with Prostaid Saw Palmetto Herbal Complex by Nature's Truth — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Prostaid Saw Palmetto Herbal Complex by Nature's Truth

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • “Stinging Nettle” is listed as a grouped ingredient — the label gives one combined amount (255 mg) without saying how much of each component you get.
  • “Saw Palmetto” is listed as a grouped ingredient — the label gives one combined amount (544 mg) without saying how much of each component you get.

Prostaid contains four active ingredients. Lycopene is a plant pigment studied for prostate and bladder health.

Stinging nettle leaf extract — the above-ground parts of the plant — is traditionally used for urinary and prostate support. Pygeum, from the African cherry tree, is used for prostate function.

Saw palmetto whole berry extract, the most studied of the four, is the core ingredient in many prostate supplements. The capsule also contains inactive ingredients: rice powder, gelatin, magnesium stearate, and silica, which are standard binders and fillers.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Leading herbs for men's prostate health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Non-neurogenic lower urinary tract symptoms (LUTS), Prostate cancer, Prostatitis, Urinary flow — and 1 related terms.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Lycopene is rated "Possibly Effective" for Prostate cancer.
  • Also on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH).

The evidence for these ingredients varies. Saw palmetto for benign prostate enlargement (BPH) shows only possibly ineffective evidence — meaning studies haven't confirmed it works well for that common use.

For saw palmetto after prostate surgery (TURP), evidence is possibly effective. Pygeum for BPH is likely effective, making it one of the stronger players here.

Lycopene is possibly effective for prostate cancer risk but possibly ineffective for bladder cancer. Stinging nettle for diabetes is possibly effective, but its effectiveness for prostate or urinary symptoms hasn't been well established.

Overall, the evidence is mixed and modest.

The evidence, ingredient by ingredient Lycopene Stinging Nettle Pygeum Saw Palmetto

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lycopene from food is safe, but supplements aren't well studied in pregnancy or breastfeeding — talk with your doctor before using if you're pregnant or nursing. Gastrointestinal side effects like diarrhea, nausea, and upset stomach can occur.

Stinging nettle is generally well tolerated with mild side effects (constipation or diarrhea), but it should be avoided in pregnancy due to traditional concerns about uterine effects and lack of safety data. Breastfeeding safety isn't established, so skip it while nursing.

Saw palmetto is well tolerated overall; mild, reversible side effects include abdominal pain, diarrhea, nausea, and headache. Like the others, it's best avoided in pregnancy and while breastfeeding.

Pygeum is generally well tolerated short-term, though long-term safety data are limited — also avoid in pregnancy and breastfeeding.

Side effects, ingredient by ingredient Lycopene Stinging Nettle Pygeum Saw Palmetto

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Lycopene, Stinging Nettle, Saw Palmetto.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 336 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product if you take blood thinners like warfarin or antiplatelet drugs like aspirin — lycopene and saw palmetto may increase bleeding risk. If you're on blood sugar medication (diabetes drugs), water pills (diuretics), or lithium, stinging nettle's additive effects need monitoring.

Estrogens and birth control drugs may be less effective if you're on saw palmetto. Also watch for any interactions with your specific medications using the search tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is geared toward men's prostate health, particularly those with BPH or concerned about prostate cancer. If you take blood thinners, diabetes meds, lithium, diuretics, or hormonal contraceptives, you need to check with your pharmacist before starting.

If you're pregnant or breastfeeding, talk with your doctor first. It's a multi-ingredient product with modest evidence and real drug interactions, so it's not a grab-and-go.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prostaid Saw Palmetto Herbal Complex, straight from the product label.

Brand Nature's Truth
Barcode (UPC) 840093112101
Net contents 60 Quick Release Capsule(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 306798
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prostaid Saw Palmetto Herbal Complex by Nature's Truth, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Quick Release Capsule(s)
Maximum serving Sizes:
2 Quick Release Capsule(s)
Servings per container
30
UPC/BARCODE
840093112101
IngredientAmount% DV
Lycopene1 mg--
Stinging Nettle Leaf Extract25.5 mg--
Stinging Nettle255 mg--
Pygeum454 mg--
Saw Palmetto544 mg--
Saw Palmetto Whole Berry Extract54.4 mg--

Other ingredients: Rice, Powder, Gelatin, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

100% Quality Satisfaction Guarantee

Our Non-GMO Pledge Visit our website

General Statements

Vitamins

Formula

Just for men

Leading herbs for men's health

Formulation

Gluten free Non GMO

No gluten, wheat, yeast, milk, lactose, soy, artificial color, artificial flavor, artificial sweetener, preservatives. Non-GMO

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adult men, take two (2) quick release capsules twice daily, preferably with meals.

Precautions

Warning: This product is intended for use by men and is not intended for use by women.

If you are taking any medications or have any medical condition, consult your doctor before use.

If any adverse reactions occur, immediately stop using this product and consult your doctor.

Not intended for use by persons under the age of 18.

If seal under cap is damaged or missing, do not use.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Copyright 2020 Nature's Truth LLC

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prostaid Saw Palmetto Herbal Complex by Nature's Truth label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prostaid Saw Palmetto Herbal Complex label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prostaid Saw Palmetto Herbal Complex by Nature's Truth

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Quick Release Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lycopene

Interacts with
122 drugs
1 mg per serving

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene monograph & interactions

Stinging Nettle

Interacts with
164 drugs
255 mg per serving

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...

Stinging Nettle monograph & interactions

Pygeum

No known
interactions
454 mg per serving

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum monograph & interactions

Saw Palmetto

Interacts with
174 drugs
544 mg per serving

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...

Saw Palmetto monograph & interactions

Other (inactive) ingredients: Rice, Powder, Gelatin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prostaid Saw Palmetto Herbal Complex by Nature's Truth Drug Interactions

Want to check YOUR meds against Prostaid Saw Palmetto Herbal Complex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
336Drugs
336 Moderate

Ingredients driving the most interactions

Saw Palmetto 174
Stinging Nettle 164
Lycopene 122

Individual Drug Interactions

The ingredients in Prostaid Saw Palmetto Herbal Complex interact with 336 drugs. Click any drug to see the details.

3 of the 4 ingredients in Prostaid Saw Palmetto Herbal Complex interact with drugs. Each result below shows which ingredient is responsible. Saw Palmetto Stinging Nettle Lycopene

Each ingredient & the kinds of drugs it affects

For each ingredient in Prostaid Saw Palmetto Herbal Complex with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Saw Palmetto3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto full monograph & interactions

Stinging Nettle4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
Stinging Nettle full monograph & interactions

Lycopene1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prostaid Saw Palmetto Herbal Complex, from the product label.

Nature's Truth

See all Nature's Truth products
Name
Nature's Truth LLC
City
Ronkonkoma
State
NY
ZipCode
11779
Phone Number
1-844-544-1030
Web Address
naturestruthproducts.com
Pharmacist Counseling Corner

Prostaid Saw Palmetto Herbal Complex by Nature's Truth: Common Questions

Does Prostaid Saw Palmetto Herbal Complex by Nature's Truth interact with any medications?
Yes. Based on its ingredients, Prostaid Saw Palmetto Herbal Complex has a known interaction with 336 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prostaid Saw Palmetto Herbal Complex contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for enlarged prostate (BPH)?
The evidence is mixed. Saw palmetto, which is a main ingredient here, hasn't been shown to work well for BPH. But pygeum, another ingredient, is likely effective for it. Your results may depend on the dose and how long you take it — talk with your doctor about what to expect.
Can I take this if I'm on warfarin?
Not without checking with your pharmacist first. Saw palmetto may increase bleeding risk, and stinging nettle contains vitamin K, which can interfere with warfarin's job. Your doctor may need to monitor you closely or adjust your dose.
What side effects might I have?
Most common are mild gastrointestinal ones: diarrhea, constipation, nausea, and abdominal pain. Headache, dizziness, and fatigue have been reported with saw palmetto. Side effects are usually reversible and go away when you stop.
Is it safe during pregnancy?
No. Saw palmetto and stinging nettle should both be avoided in pregnancy — saw palmetto is rated likely unsafe, and stinging nettle has traditional concerns about uterine effects plus lack of safety data. Talk with your doctor before using if you're pregnant or planning to become pregnant.
What's lycopene in this for?
Lycopene is a pigment from tomatoes and other red plants. It's possibly effective for prostate cancer risk, but that evidence is still developing. It's also possibly ineffective for bladder cancer based on current research.
Can I take this with my diabetes medication?
Stinging nettle may lower blood glucose, so it could add to your medication's effect. This could be risky if it drops your blood sugar too much. Check with your pharmacist or doctor before adding it to your routine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Prostaid Saw Palmetto Herbal Complex is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prostaid Saw Palmetto Herbal Complex label
Go deeper

The Full Monographs Behind Prostaid Saw Palmetto Herbal Complex’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph → Herb & supplement monograph

Stinging Nettle

Interacts with 164 drugs

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...

Read the full Stinging Nettle monograph → Herb & supplement monograph

Pygeum

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some studies suggest modest benefit for these s...

Read the full Pygeum monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph →
Sources

Sources & How We Checked

Prostaid Saw Palmetto Herbal Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 58 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
  6. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
  7. Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Stinging Nettle 23 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  5. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
  8. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
  9. Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
  10. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8. PubMed
  11. Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993;15(6):1011-1020.
  12. Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. Complement Ther Med 1999;7(3):126-131. PubMed
  13. Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacol 2000;73(1-2):95-100. PubMed
  14. Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N.Z.Med.J. 2007;120(1265):U2803.
  15. Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther.Med. 2008;16(2):66-72. PubMed
  16. Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Altern.Ther.Health Med. 2009;15(4):60-61.
  17. Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Clin Exp Dermato PubMed
  18. Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. Br.J Dermatol. 1988;119(2):269-270. PubMed
  19. Patten G. Medicinal plant review: Urtica. Aust J Med Herbalism 1993;5(1):5-13.
  20. Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Contact Dermatitis. 2017 Nov;77(5):335-37. PubMed
  21. Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea. Am J Case Rep 2021;22:e933999. PubMed
  22. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
  23. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed

See these in context on the Stinging Nettle monograph →

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Saw Palmetto 22 references
  1. Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
  2. Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
  3. Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
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See these in context on the Saw Palmetto monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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