Prostol Ingredients & Drug Interactions
by Nature's Way
What is this page for?
First and foremost: checking Prostol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Prostol is a dietary supplement by Nature's Way with 2 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary problems, hair loss.Based on those ingredients, 336 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sabal extract, Urtica extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Prostol by Nature's Way
Ask about any prescription or over-the-counter medication and we check it for interactions with Prostol by Nature's Way — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Prostol by Nature's Way
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Prostol contains two active herbal ingredients: sabal extract (saw palmetto) and urtica extract (stinging nettle). The product also includes inactive ingredients—plant glycerides, gelatin, glycerin, soybean oil, and food colorings (carmel, titanium dioxide, and carmine)—which serve as capsule material and binders.
Does it work?
Leans against
Saw palmetto is possibly effective for transurethral resection of the prostate (TURP), a surgical procedure, but the evidence suggests it's possibly ineffective for benign prostatic hyperplasia (BPH)—a common prostate condition. For other potential uses—chronic bronchitis, male pattern baldness, and lower urinary tract symptoms—the evidence in our data isn't established.
Stinging nettle is possibly effective for diabetes and possibly helpful for benign prostatic hyperplasia, but the evidence for hay fever, anemia, asthma, and gingivitis isn't established in the data we hold.
How safe is it?
Well-documented data
Both ingredients are generally well tolerated, though saw palmetto's adverse effects tend to be mild and reversible. The most common side effects from saw palmetto are abdominal pain, constipation, decreased libido, diarrhea, dizziness, fatigue, headache, nausea, rhinitis, and vomiting; rare cases of heart problems have been reported.
Stinging nettle commonly causes constipation or diarrhea. The safety data advises against use during pregnancy for both ingredients due to hormonal effects (saw palmetto) or uterine concerns (stinging nettle) and insufficient safety information.
Breastfeeding is not recommended with either ingredient until you've discussed it with your doctor.
Meds to double-check
Moderate interaction found
Before taking Prostol, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (such as warfarin, aspirin, or clopidogrel)—saw palmetto may increase bleeding risk. Also double-check if you take estrogens, contraceptive drugs, diabetes medications, diuretics, lithium, or warfarin specifically, as the product may interfere with how these work.
The bottom line
Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Prostol may be worth considering if you're interested in herbal support for prostate or urinary health, but you'll want to talk it over with your doctor or pharmacist first—especially if you take blood thinners, diabetes medications, diuretics, contraceptives, hormone therapy, or lithium. It's not appropriate during pregnancy or breastfeeding.
Check your exact medications against the interaction tool on this page before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Prostol, straight from the product label.
| Brand | Nature's Way |
|---|---|
| Barcode (UPC) | 033674149348 |
| Net contents | 120 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 26, 2020 |
| DSLD ID | 213096 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Prostol by Nature's Way, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Sabal extract | 160 mg | -- |
| Urtica extract | 120 mg | -- |
Other ingredients: Plant Glycerides, Gelatin, Glycerin, Soybean Oil, Carmel color, Titanium Dioxide color, Carmine color
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Dual action prostate support
Gluten free. No salt, yeast-derived ingredients, corn, wheat, dairy products, or artificial flavors, or preservatives.
Formula
Prostol brings a synergistic combination of Saw Palmetto (Sabal) and Nettle that, through clinical research, has been shown to support prostate health.
Saw Palmetto & Nettle
General Statements
At Nature's Way we believe nature knows best. That's why our mission is to seek out the best herbs the earth has to give. It's the way we deliver uncompromising quality and help you live healthier.
Nature’s Way Since 1969
280 mg per serving
Product of Germany
Bottles made from 97% post-consumer recycled plastic
FDA Disclaimer Statement
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommendation: Take 1 softgel twice daily.
Precautions
Not formulated for women.
If you are taking any medications, consult a healthcare professional before use.
Contains soy
Keep out of reach of children.
Safety sealed with printed inner seal. Do not use if seal is broken or missing.
Brand IP Statement(s)
2019 Nature’s Way Brands, LLC
Seals/Symbols
Quality Global Sourcing Bottled & Tested In the USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Prostol by Nature's Way label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Prostol by Nature's Way
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sabal extract
Interacts with174 drugs
Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...
Sabal extract monograph & interactionsUrtica extract
Interacts with164 drugs
Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...
Urtica extract monograph & interactionsOther (inactive) ingredients: Plant Glycerides, Gelatin, Glycerin, Soybean Oil, Carmel color, Titanium Dioxide color, Carmine color. These complete the product’s ingredient list but are not active constituents.
Prostol by Nature's Way Drug Interactions
HelloPharmacist Interaction Report
Prostol by Nature's Way contains saw palmetto and stinging nettle, both of which interact with medications.
The most serious concern is saw palmetto's potential to increase bleeding risk when combined with blood thinners or antiplatelet drugs (anticoagulants or antiplatelets)—a Moderate severity interaction that could affect how these drugs work.
Read the full breakdown — every affected drug type, severity by severity
Saw palmetto may also reduce the effectiveness of estrogens and contraceptive drugs through antiestrogenic effects. Stinging nettle presents its own set of interactions: it may have additive effects with diabetes medications and diuretics, theoretically increase lithium levels (which could require a dose adjustment), and potentially decrease the effectiveness of warfarin because of its vitamin K content.
Altogether, these interactions span 336 individual medications. Before you start Prostol, run your current medications through the search tool on this page or check with your doctor or pharmacist—especially if you take any blood thinner, diabetes medication, diuretic, or hormone-based drug.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Prostol?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Prostol interact with 336 drugs. Click any drug to see the details.
2 of the 2 ingredients in Prostol interact with drugs. Each result below shows which ingredient is responsible. Sabal extract Urtica extract
AbciximabReoPro
How Abciximab interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Urtica Extract + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Urtica ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Urtica Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Prostol — through 1 ingredient. Tap an ingredient for the detail:
Sabal ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Sabal Extract + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Prostol with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Sabal extract
Anticoagulant/Antiplatelet Drugs
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.
Contraceptive Drugs
Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.
Estrogens
Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.
Urtica extract
Antidiabetes Drugs
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.
Diuretic Drugs
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.
Lithium
Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.
Warfarin (Coumadin)
There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.
Brand information
Manufacturer and brand details for Prostol, from the product label.
Nature's Way
See all Nature's Way products- Name
- Nature's Way Brands, LLC
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- 1-800-962-8873
- Web Address
- naturesway.com
Prostol by Nature's Way: Common Questions
Does Prostol by Nature's Way interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Prostol if I'm pregnant or breastfeeding?
What are the most common side effects?
Does Prostol actually work for prostate health?
What's in Prostol besides the active ingredients?
Why is there a warning about warfarin and stinging nettle?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Prostol is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Prostol’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Saw Palmetto
Interacts with 174 drugsSaw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...
Read the full Saw Palmetto monograph → Herb & supplement monographStinging Nettle
Interacts with 164 drugsStinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...
Read the full Stinging Nettle monograph →Sources & How We Checked
Prostol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 45 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Saw Palmetto 22 references
- Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
- Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
- Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
- Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
- Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
- Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
- Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
- Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
- Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
- Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
- Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
- Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
- Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
- Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
- Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
- Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
- Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
- Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
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