Psyllium Husk Caps 700 mg Ingredients & Drug Interactions
by NOW
What is this page for?
First and foremost: checking Psyllium Husk Caps 700 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Psyllium Husk Caps 700 mg is a dietary supplement by NOW with 3 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,031 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Apple Pectin, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Psyllium Husk Caps 700 mg by NOW
Ask about any prescription or over-the-counter medication and we check it for interactions with Psyllium Husk Caps 700 mg by NOW — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Psyllium Husk Caps 700 mg by NOW
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains four active ingredients: soluble fiber, insoluble fiber, apple pectin powder, and psyllium. Together they provide dietary fiber to support digestive function.
Fiber in supplements like this works to add bulk to your stool and help move things along in your digestive tract. The product also contains inactive ingredients — hypromellose, stearic acid, and silicon dioxide — which are fillers and capsule materials.
Does it work?
Strong evidence
Apple pectin in this product has possibly effective evidence for high cholesterol (hypercholesterolemia). For blood sugar control in prediabetes and for other uses like radiation exposure, the evidence isn't established in the data we hold.
We don't have effectiveness ratings on file for the soluble fiber, insoluble fiber, or psyllium itself in this specific product.
How safe is it?
Well-documented data
Apple pectin is generally well tolerated in typical supplement amounts. The most common side effects are diarrhea, gas, loose stools, and mild cramps.
Allergic reactions, including anaphylaxis, are rare but possible in sensitive individuals. For pregnancy and breastfeeding, pectin from food amounts is considered likely safe, but concentrated supplement safety hasn't been well studied in either situation — talk with your doctor or pharmacist before using this product if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Check your medications if you take digoxin (a heart medication), lovastatin or similar cholesterol drugs, or tetracycline antibiotics. Pectin may reduce how well your body absorbs these, potentially making them less effective.
Use the medication checker on this page to confirm your specific drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This fiber supplement may help with cholesterol if that's your goal, but the apple pectin in it can interfere with several important medications. If you take digoxin, lovastatin, or tetracycline antibiotics, check with us first.
Run your complete medication list through the checker on this page before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Psyllium Husk Caps 700 mg, straight from the product label.
| Brand | NOW |
|---|---|
| Barcode (UPC) | 733739059741 |
| Net contents | 360 Veg Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 23, 2024 |
| DSLD ID | 313996 |
| Product type | Fiber And Other Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Halal, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Psyllium Husk Caps 700 mg by NOW, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Dietary Fiber | 1 Gram(s) | 4% |
| Soluble Fiber | 0.9 Gram(s) | -- |
| Insoluble Fiber | 0.1 Gram(s) | -- |
| Apple Pectin, Powder | 100 mg | -- |
| Psyllium | 1.4 Gram(s) | -- |
Other ingredients: Hypromellose, Stearic Acid, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: Take 2 capsules with 8 oz. glass of liquid, 2 to 3 times a day.
Formula
Surveys have shown that the fiber content of the American diet is typically about half of recommended levels. Psyllium Husks and Apple Pectin can be a convenient way to increase the intake of dietary fiber. Psyllium has the ability to swell up to 50 times its initial volume when added to liquid. This bulking action can play an important role in maintaining regularity and gastrointestinal health.
Psyllium Husk Caps 700 mg with 50 mg of Apple Pectin
Triangle K (Kosher)
Crescent C (Halal)
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Caution: For adults only.
Consult physician if pregnant/nursing, taking medication, or have a medical condition.
Keep out of reach of children.
Notice: This product should be taken with at least a full glass of liquid. Taking this product without enough liquid may cause choking. Do not take this product if you have difficulty swallowing.
Made and quality tested in the USA with globally sourced ingredients.
Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Formulation
Natural color variation may occur in this product.
Intestinal health Helps maintain regularity
Non-GMO
Vegetarian/vegan
Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.
Storage
Store in a cool, dry place after opening.
FDA Statement of Identity
A Dietary Supplement
Seals/Symbols
Triangle K (Kosher)
GMP Quality Assured Crescent C (Halal)
General Statements
Digestive Family owned since 1968.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Psyllium Husk Caps 700 mg by NOW label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Psyllium Husk Caps 700 mg by NOW
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Veg Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactions- › Soluble Fiber
- › Insoluble Fiber
Apple Pectin, Powder
Interacts with23 drugs
Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...
Apple Pectin, Powder monograph & interactionsPsyllium
Other (inactive) ingredients: Hypromellose, Stearic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Psyllium Husk Caps 700 mg by NOW Drug Interactions
HelloPharmacist Interaction Report
NOW's Psyllium Husk Caps contain apple pectin, which has documented interactions with several medications.
The most serious concern involves digoxin (a heart medication), where pectin may reduce absorption by about 62%, potentially lowering its effectiveness. This is a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Pectin also interacts with cholesterol-lowering drugs like lovastatin and with tetracycline antibiotics (used for infections). Both are Moderate severity — pectin may reduce how well your body absorbs these medications, making them less effective.
We cannot check the soluble fiber, insoluble fiber, or psyllium itself in this product; interaction data isn't held for those ingredients.
Altogether, these interactions span 23 individual medications. Before you start this supplement, run your medications through the checker on this page — especially if you take heart medications, cholesterol drugs, or antibiotics.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Psyllium Husk Caps 700 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Psyllium Husk Caps 700 mg interact with 2,031 drugs. Click any drug to see the details.
2 of the 3 ingredients in Psyllium Husk Caps 700 mg interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Apple Pectin, Powder
Alogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Metformin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Psyllium Husk Caps 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Amphotericin, Tetracycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amphotericin, Tetracycline interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Psyllium Husk Caps 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Canagliflozin, Metformin Hydrochloride interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Carbamazepine (tegretol) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Carbamazepine interactionChlortetracyclineAureomycin
How Chlortetracycline interacts with Psyllium Husk Caps 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Chlortetracycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Chlortetracycline interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Dapagliflozin Propanediol, Metformin interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDemeclocyclineDeclomycin
How Demeclocycline interacts with Psyllium Husk Caps 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Demeclocycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Demeclocycline interactionDigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Psyllium Husk Caps 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Apple Pectin, PowderDigoxin (lanoxin) Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
Read the full Apple Pectin, Powder + Digoxin interactionDietary FiberOral Drugs, Digoxin (lanoxin) Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Digoxin interactionDoripenemDoribax
How Doripenem interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Doripenem interactionDoxycyclineDoryx, Doxy, Doxy-D, Doxycin, Doxycycline Injection, Doxylin +6 more
How Doxycycline interacts with Psyllium Husk Caps 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Doxycycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Doxycycline interactionDoxycycline HyclateActiclate, Acticlate Cap, Lymepak
How Doxycycline Hyclate interacts with Psyllium Husk Caps 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Doxycycline Hyclate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Doxycycline Hyclate interactionDoxycycline MonohydrateErfacea
How Doxycycline Monohydrate interacts with Psyllium Husk Caps 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Doxycycline Monohydrate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Doxycycline Monohydrate interactionDoxycylineDoxychel
How Doxycyline interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Doxycyline interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Empagliflozin, Metformin Hydrochloride interactionEravacyclineXerava
How Eravacycline interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Apple Pectin, PowderTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Apple Pectin, Powder + Eravacycline interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ertugliflozin, Metformin Hydrochloride interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Glipizide, Metformin interactionGlyburide, MetforminGlucovance
How Glyburide, Metformin interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Glyburide, Metformin interactionLinagliptin, Metformin HydrochlorideJentadueto XR
How Linagliptin, Metformin Hydrochloride interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Linagliptin, Metformin Hydrochloride interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Lithium Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Lithium Carbonate (prescription Drug) interactionLovastatinAltocor, Mevacor
How Lovastatin interacts with Psyllium Husk Caps 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Apple Pectin, PowderLovastatin (mevacor) Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Read the full Apple Pectin, Powder + Lovastatin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Lovastatin interactionMetforminGlucophage, Metformin
How Metformin interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Metformin interactionMetformin HydrochlorideRiomet ER
How Metformin Hydrochloride interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Metformin Hydrochloride interactionMetformin, LinagliptinJentadueto
How Metformin, Linagliptin interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Metformin, Linagliptin interactionMetformin, RosiglitazoneAvandamet
How Metformin, Rosiglitazone interacts with Psyllium Husk Caps 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Metformin, Rosiglitazone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Psyllium Husk Caps 700 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Apple Pectin, Powder
Digoxin (Lanoxin)
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.
Lovastatin (Mevacor)
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.
Tetracycline Antibiotics
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.
Brand information
Manufacturer and brand details for Psyllium Husk Caps 700 mg, from the product label.
NOW
See all NOW products- Name
- NOW FOODS
- Street Address
- 395 S. Glen Ellyn Rd.
- City
- Bloomingdale
- State
- IL
- ZipCode
- 60108
- Web Address
- nowfoods.com
Psyllium Husk Caps 700 mg by NOW: Common Questions
Does Psyllium Husk Caps 700 mg by NOW interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What side effects might I notice?
Will this really help my cholesterol?
Can this help with blood sugar or prediabetes?
What exactly is in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Psyllium Husk Caps 700 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Psyllium Husk Caps 700 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographPectin
Interacts with 23 drugsPectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...
Read the full Pectin monograph →Sources & How We Checked
Psyllium Husk Caps 700 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 29 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Pectin 11 references
- Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
- Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
- Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
- Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
- Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
- Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
- Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
- Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
- Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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