Major interaction on record — check this product against your medications before combining. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Pure Aloe Force Ingredients & Drug Interactions

by Herbal Answers

Pure Aloe Force label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure Aloe Force against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Pure Aloe Force is a dietary supplement by Herbal Answers with 2 active ingredients. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Aloe vera. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pure Aloe Force by Herbal Answers

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Aloe Force by Herbal Answers — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pure Aloe Force by Herbal Answers

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Pure Aloe Force is a liquid supplement with one active ingredient: aloe vera. The product also contains potassium sorbate, an inactive preservative.

Aloe vera is the whole plant material—both the inner gel and the outer latex—which explains why this product carries both the gentler effects of aloe gel and the stronger laxative effects of aloe latex.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin and digestive health support.
  • We looked for evidence on: Burns, Wound healing, Dry skin, Constipation, Irritable bowel syndrome (IBS), Peptic ulcers — and 4 related terms.
  • The strongest evidence on file: Aloe is rated "Possibly Effective" for Burns (Natural Medicines).
  • Also on file: Aloe is rated "Possibly Effective" for Constipation.
  • Also on file: Aloe is rated "Insufficient Reliable Evidence To Rate" for Diaper rash, Dry skin, Atopic dermatitis (eczema), Ulcerative colitis, and more.

Aloe vera in this form is possibly effective for acne, obesity, diabetes, psoriasis, burns, and constipation, according to clinical evidence. That means there's some preliminary research backing these uses, but stronger proof is still needed.

How well it'll work for you depends on your individual situation and how you use it.

The evidence, ingredient by ingredient Aloe

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Topical aloe gel is generally well tolerated, but oral aloe latex—which this liquid product contains—carries more risk, especially at high doses or with long-term use. You may experience abdominal pain, cramps, or diarrhea.

Rarely, prolonged use can cause serious problems like severe potassium loss (low potassium / hypokalemia), muscle weakness, and heart rhythm changes. Avoid taking this product by mouth during pregnancy because aloe latex can stimulate the uterus and act as a strong laxative.

Also avoid it while breastfeeding due to limited safety data and its laxative effects.

Side effects, ingredient by ingredient Aloe

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Aloe.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications.
  • For scale: 461 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Pure Aloe Force, check with your doctor or pharmacist if you take digoxin or other heart medications (Major risk), blood thinners or warfarin, diabetes drugs, water pills, other laxatives, or any medications broken down by the liver enzyme CYP1A2 (Minor risk). The laxative and potassium-depleting effects of aloe latex are the main culprits.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Aloe vera liquid may help with constipation, burns, or skin conditions, but it's not for everyone. If you take heart, blood-thinning, diabetes, or water-pill medications, you'll need to check with your doctor or pharmacist first—the risks are real.

Pregnant or breastfeeding? Skip it.

Talk it over with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Aloe Force, straight from the product label.

Brand Herbal Answers
Barcode (UPC) 639764102646
Net contents 32 fl. Oz.; 946 mL
Market status On market
Date entered into DSLD Mar 23, 2018
DSLD ID 173846
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Aloe Force by Herbal Answers, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 fl. Oz.
Maximum serving Sizes:
1 fl. Oz.
Servings per container
32
UPC/BARCODE
639764102646
IngredientAmount% DV
Calories3 Calorie(s)--
Total Carbohydrates0.75 Gram(s)1%
Sugar0 Gram(s)--
Calories from Fat0 Calorie(s)--
Total Fat0 Gram(s)--
Aloe vera29.25 Gram(s)--

Other ingredients: Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Closest To Nature Is Best Protecting Aloe's Lif-Force-Full structures maximizes its potency, effectiveness & its biologicial activity and availability.

Raw, uncooked, never heated No heat is ever applied at any time in any part of processing from field to bottle.

Never concentrated, diluted or dried. Nature's original design, balance, proportions and synergy are protected, delivering the full power of Aloe's biological form & activity.

Our unique processing removes impurities without damaging filtering. Non-Laxative Formulation

Processed to protect & deliver Aloe's naturally occurring constituents including its fragile enzymes & unique, large, 'growth' polysaccharides (Aloe's acetylated beta-glucomannans).

"Live" Raw Whole

Maximum strength, never heated

Designed by nature - unbroken by processing.

Health - Pure & Simple A nutritious, dietary supplement purified to fortify your health daily.

Natural color & flavor will vary

Experience The Difference Finally, we can experience the full Life-Force of Aloe & its full promise because we protect nature's sacred designs for life, energy & health. Herbal Answers Promise We offer the whole truth of our Aloe processing.

Dr. Jeri L.

Original health with original designs created & designed by nature Protected, unbroken & delivered by Herbal Answers' unique processing Please recycle

The aloe answer

Brand IP Statement(s)

Raw-Purified, Bio-Protected Aloe processing guarantee

AloeForce is uniquely stabilized & purified without any heat or any damaging processing.

Life - Force - Full

Raw-purified

Bio-Protected for life & purity Experience the Full-Life-Force of Aloe

Copyright 1995-2013 Herbal Answers Inc.

Bio-Protected Pure Aloe Force

Revolutionary Bio-Protective Processing makes our liquified, whole, raw, 'live' aloe: Completely purified - Finally safe as a daily health supplement. Protected to deliver - All the 'live' Aloe plant has to offer.

If Pure Aloe Force is not all that we say it is we will offer a full refund.

Health Made Simple

Our Bio-Protective processing protects these intricately woven constituents to feed the cells, tissues and organs of our bodies as only a raw 'live', whole food can.

"Life" feeds "life" Feed your life with Life-Force-Full Aloe

Formulation

No water added or removed.

Aloin & emodins completely removed to less than or equal to 1 ppm from the whole leaf & inner gel of the plant with no damaging filter.

Naturally gluten free; non-GMO Aloin/toxin free

Formula

Whole leae & inner gel of the Barbadensis-Miller plant is used to include the nutrient rich leaf.

Organically grown liquified Aloe vera leaf

Finally, a truly raw, 'live' liquified Aloe that is purified for daily use, tastes good & is processed to protect and deliver the full promise of Aloe.

Bio-Protected Aloe Vera The Promise Fulfilled

The magnificent Aloe plant, that is designed to be self-sufficient & thrive in the desert, feeds us in unique ways with its 250+ naturally occurring constituents including: Enzymes, amino acids, essential fatty acids, vitamins, minerals, glycoproteins, sterols, growth factors, & Aloe's unique 'growth' polysaccharides & glucomannans.

Suggested/Recommended/Usage/Directions

Uniquely raw & completely purified AloeForce allows for daily use & removes Aloe's usual contra-indications & bitter taste.

Suggested Usage: Usage will always vary and fluctuate according to your health needs. From 1/2 to 1 oz. or more, two-five times a day as needed. (One capful equals 1 oz) Best if split amounts throughout the day, on an empty stomach (but can be used anytime). Up to 4 oz at any one time for maximum absorption. Introduce gradually and build to desired daily amounts.

May be mixed with any cold drink

FDA Statement of Identity

Dietary Supplement

Storage

Refrigerate after opening.

Precautions

Please discuss product usage with your health care practitioner. Follow usage recommendations.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure Aloe Force by Herbal Answers label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure Aloe Force label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure Aloe Force by Herbal Answers

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 fl. Oz. Dosage formLiquid Servings per container32 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 Gram(s) per serving

Aloe vera

Interacts with
461 drugs
29.25 Gram(s) per serving

Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...

Aloe vera monograph & interactions

Other (inactive) ingredients: Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure Aloe Force by Herbal Answers Drug Interactions

Want to check YOUR meds against Pure Aloe Force?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
461Drugs
1 Major 304 Moderate 156 Minor

Ingredients driving the most interactions

Aloe vera 461

Individual Drug Interactions

The ingredients in Pure Aloe Force interact with 461 drugs. Click any drug to see the details.

1 of the 2 ingredients in Pure Aloe Force interact with drugs. Each result below shows which ingredient is responsible. Aloe vera

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Aloe Force with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Aloe vera7 drug types · 461 drugs

Digoxin (Lanoxin)

Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.

Likelihood Possible Evidence D
Antidiabetes Drugs

Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.

Likelihood Possible Evidence D
Stimulant Laxatives

Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Aloe vera full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure Aloe Force, from the product label.

Herbal Answers

See all Herbal Answers products
Name
Herbal Answers, Inc.
Street Address
PO Box 1110
City
Saratoga Springs
State
NY
ZipCode
12866
Phone Number
518-581-1968
Web Address
www.herbalanswers.com
Pharmacist Counseling Corner

Pure Aloe Force by Herbal Answers: Common Questions

Does Pure Aloe Force by Herbal Answers interact with any medications?
Yes. Based on its ingredients, Pure Aloe Force has a known interaction with 461 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Aloe Force contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is aloe vera juice safe to drink?
Oral aloe latex is generally well tolerated in typical doses, but it carries more risk than topical use—especially at high doses or long-term. You may get abdominal pain, cramps, or diarrhea. Rarely, overuse can cause serious potassium loss and heart rhythm problems. If you're on any medications, check with your pharmacist first.
Can I take this if I'm pregnant or breastfeeding?
No—the safety data advises against oral aloe during pregnancy because the latex may stimulate the uterus and act as a strong laxative. Avoid it while breastfeeding too, because there's limited safety data and the laxative effects could affect your baby.
Will this help my constipation?
Aloe vera is possibly effective for constipation based on preliminary research. It works as a laxative, but that's also why it carries risks if you take it long-term or at high doses—overuse can cause diarrhea, cramps, and electrolyte problems.
Can I use aloe vera for burns?
Aloe vera is possibly effective for burns. The topical gel is generally well tolerated with minor side effects like burning, redness, or itching in sensitive people.
What's in this product besides aloe?
Pure Aloe Force contains one active ingredient, aloe vera, plus potassium sorbate as a preservative to keep it fresh.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Aloe Force is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Aloe Force label
Go deeper

The Full Monographs Behind Pure Aloe Force’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Aloe

Interacts with 461 drugs

Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a strong laxative that can cause cramping and...

Read the full Aloe monograph →
Sources

Sources & How We Checked

Pure Aloe Force's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 41 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Aloe 41 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
  5. Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
  6. Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
  7. Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
  8. Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
  9. Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
  10. Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
  11. Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
  12. Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
  13. Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
  14. Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
  15. Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
  16. Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
  17. Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
  18. Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
  19. Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
  20. Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
  21. Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
  22. Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. PubMed
  23. Baretta, Z., Ghiotto, C., Marino, D., and Jirillo, A. Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy. Ann.Oncol. 2009;20(8):1445-1446. PubMed
  24. Hunter, D. and Frumkin, A. Adverse reactions to vitamin E and aloe vera preparations after dermabrasion and chemical peel. Cutis 1991;47(3):193-196.
  25. Alvarez-Perea, A., Garcia, A. P., Hernandez, A. L., de, Barrio M., and Baeza, M. L. Urticaria due to aloe vera: a new sensitizer? Ann.Allergy Asthma Immunol. 2010;105(5):404-405. PubMed
  26. Hogan, D. J. Widespread dermatitis after topical treatment of chronic leg ulcers and stasis dermatitis. CMAJ. 2-15-1988;138(4):336-338.
  27. Savchak VI. Acute bullous allergic dermatitis due to local application of aloe leaves. Vestnik Dermatologii i Venerologii 1977;12:44-45.
  28. Nakamura, T. and Kotajima, S. Contact dermatitis from aloe arborescens. Contact Dermatitis 1984;11(1):51. PubMed
  29. Shoji, A. Contact dermatitis to Aloe arborescens. Contact Dermatitis 1982;8(3):164-167. PubMed
  30. Morrow, D. M., Rapaport, M. J., and Strick, R. A. Hypersensitivity to aloe. Arch Dermatol. 1980;116(9):1064-1065. DOI
  31. Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower E
  32. Bhalang K, Thunyakitpisal P, Rungsirisatean N. Acemannan, a polysaccharide extracted from Aloe vera, is effective in the treatment of oral aphthous ulceration. J Altern Complement Med 2013;19(5):429-34.
  33. Hajheydari Z, Saeedi M, Morteza-Semnani K, Soltani A. Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. J Dermatolog Treat 2014;25(2):123-9.
  34. Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
  35. Lee J, Lee MS, Nam KW. Acute toxic hepatitis caused by an aloe vera preparation in a young patient: a case report with a literature review. Korean J Gastroenterol 2014;64(1):54-8. PubMed
  36. Guo X, Mei N. Aloe Vera - A Review of Toxicity and Adverse Clinical Effects. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2016;34(2):77-96.
  37. Hoogenboom TCH, Patel N, Cook NA, Williams R, Taylor-Robinson SD, Lim AKP. The effect of Aloe vera juice on liver enzymes and hepatic structure in a healthy population. Integr Med (Encinitas) 2020;19(3):30-4.
  38. Mushtaq S, Mushtaq Z, Sarfraz J, et al. Comparison of effect of aloe vera gel with aspirin and celecoxib on platelet aggregation. Professional Med J. 2020; 27(5):973-978. DOI
  39. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  40. Sabbaghzadegan S, Soltani MH, Kamalinejad M, Bahrami M, Kabir A, Dadmehr M. The effect of a standardized capsule of Aloe vera gel on the quality of life in patients with systolic heart failure: A randomized double-blind placebo-controlled clinical trial.
  41. Lewis ED, Crowley DC, Guthrie N, Evans M. Healthy adults supplemented with a nutraceutical formulation containing Aloe vera gel, rosemary and Poria cocos enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial. PubMed

See these in context on the Aloe monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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