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Dietary supplement

Pure Apple Cider Vinegar 500 mg Ingredients & Drug Interactions

by Swiss BioEnergetics

Pure Apple Cider Vinegar 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure Apple Cider Vinegar 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure Apple Cider Vinegar 500 mg is a dietary supplement by Swiss BioEnergetics with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 162 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Apple Cider Vinegar. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pure Apple Cider Vinegar 500 mg by Swiss BioEnergetics

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Apple Cider Vinegar 500 mg by Swiss BioEnergetics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pure Apple Cider Vinegar 500 mg by Swiss BioEnergetics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: apple cider vinegar at 500 mg per capsule. The remaining ingredients are inactive — hydroxypropylmethylcellulose (the capsule material) and maltodextrin (a filler).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Apple Cider Vinegar's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supporting normal blood sugar and cholesterol levels.
  • We looked for evidence on: Diabetes, Hyperlipidemia, Impaired glucose tolerance (prediabetes), Metabolic syndrome, Dyslipidemia.
  • The closest evidence on file: Apple Cider Vinegar is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Apple Cider Vinegar is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia, Impaired glucose tolerance (prediabetes).

The evidence on apple cider vinegar for the uses listed — acne, athletic performance, cognitive function, dental plaque, depression, and atopic dermatitis (eczema) — is insufficient to rate in the data we hold. That means research either hasn't been done, hasn't been solid enough, or results have been mixed.

We can't claim it works for any of these based on what's documented.

The evidence, ingredient by ingredient Apple Cider Vinegar

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

In the amounts you'd get from food, apple cider vinegar is generally well tolerated. For short-term use in supplement form, it also seems well tolerated.

However, large doses or long-term use raise concerns. One documented case involved someone drinking 250 mL (a large amount) daily for 6 years and developed low potassium, elevated kidney hormone levels, and bone loss (osteoporosis).

Topical use — applying it directly to skin — carries a risk of chemical burns and irritation. Safety data on large supplement doses over time is limited, so talk with your doctor before using high amounts for extended periods.

Side effects, ingredient by ingredient Apple Cider Vinegar

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Apple Cider Vinegar.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 162 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your doctor or pharmacist if you take digoxin (Lanoxin) for your heart, any diuretics or water pills, insulin, or other diabetes medications. The concerns center on low potassium and low blood sugar — both serious if they happen.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Apple cider vinegar in food amounts is generally well tolerated, but this supplement in larger doses over time isn't well studied. If you take heart medications like digoxin, diuretics, insulin, or diabetes drugs, you need to check with your doctor or pharmacist before starting — the interaction risks are real.

For anyone else considering it, the evidence on what it actually does for acne, skin, mood, or performance isn't established yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Apple Cider Vinegar 500 mg, straight from the product label.

Brand Swiss BioEnergetics
Barcode (UPC) 5060663810045
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD May 24, 2023
DSLD ID 284367
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Apple Cider Vinegar 500 mg by Swiss BioEnergetics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
120
UPC/BARCODE
5060663810045
IngredientAmount% DV
Apple Cider Vinegar500 mg--

Other ingredients: Hydroxypropylmethylcellulose, Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Super Rich in Acetic Acid & Pectins

Formulation

Supporting Normal Blood Sugar & Cholesterol Levels

Suitable for Vegetarians or Vegans

Seals/Symbols

Manufactured in the UK GMP Consistent Quality

FDA Statement of Identity

Food Supplement

Suggested/Recommended/Usage/Directions

DIRECTIONS: Adults, take 1-3 capsules daily with water and food. Do not exceed recommended daily dose.

Precautions

ALLERGY ADIVCE: Although rigorous precautions are taken to prevent any cross-contamination, this product is manufactured in a facility that also handles allergy-based materials such as nuts, seeds, milk, egg, cereals, soya, mustard, celery, fish, crustaceans and sulphites.

CAUTIONS: Always consult your health practitioner before taking nutritional supplements, especially if you are taking medication or are under medical supervision. Not recommended for use by pregnant or breastfeeding women.

Do not exceed recommended daily dose. You should not take supplements as a substitute for a varied balanced diet or healthy lifestyle.

Store in a cool dry place, out of reach of children.

Storage

Store in a cool dry place, out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure Apple Cider Vinegar 500 mg by Swiss BioEnergetics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure Apple Cider Vinegar 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure Apple Cider Vinegar 500 mg by Swiss BioEnergetics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Apple Cider Vinegar

Interacts with
162 drugs
500 mg per serving

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar monograph & interactions

Other (inactive) ingredients: Hydroxypropylmethylcellulose, Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure Apple Cider Vinegar 500 mg by Swiss BioEnergetics Drug Interactions

Want to check YOUR meds against Pure Apple Cider Vinegar 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
162Drugs
89 Moderate 73 Minor

Ingredients driving the most interactions

Apple Cider Vinegar 162

Individual Drug Interactions

The ingredients in Pure Apple Cider Vinegar 500 mg interact with 162 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pure Apple Cider Vinegar 500 mg interact with drugs. Each result below shows which ingredient is responsible. Apple Cider Vinegar

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Apple Cider Vinegar 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure Apple Cider Vinegar 500 mg, from the product label.

Swiss BioEnergetics

See all Swiss BioEnergetics products
Name
Countercom Ltd
Street Address
310 Harrow Road
City
Middlesex
State
HA9 6LL
Web Address
www.swissbioenergetics.com
Pharmacist Counseling Corner

Pure Apple Cider Vinegar 500 mg by Swiss BioEnergetics: Common Questions

Does Pure Apple Cider Vinegar 500 mg by Swiss BioEnergetics interact with any medications?
Yes. Based on its ingredients, Pure Apple Cider Vinegar 500 mg has a known interaction with 162 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Apple Cider Vinegar 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I take a diuretic or water pill?
Not without checking first. Apple cider vinegar might lower your potassium when you take diuretics together, and low potassium can cause serious problems. Talk with your doctor or pharmacist about whether it's safe for you.
Is apple cider vinegar safe to use long-term?
In food amounts, yes. In larger supplement doses over years, we don't have enough safety data, and one case report showed serious effects like low potassium and bone loss from very high daily intake for 6 years. Stick to normal food amounts unless your doctor clears it.
Does this actually work for acne or skin problems?
The evidence we have isn't strong enough to say. For acne, eczema, and dental plaque, we can't rate apple cider vinegar as proven or unproven — the research just isn't solid.
What about applying it directly to skin?
The data shows topical use — putting it on your skin — can cause chemical burns and irritation. A few cases have been reported, including one from a single application. It's not recommended for direct skin use.
Can I take this while pregnant or breastfeeding?
We don't have safety data on file for apple cider vinegar in pregnancy or lactation. Talk with your doctor or midwife before using it — they can give you personalized advice based on your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Apple Cider Vinegar 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Apple Cider Vinegar 500 mg label
Go deeper

The Full Monographs Behind Pure Apple Cider Vinegar 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph →
Sources

Sources & How We Checked

Pure Apple Cider Vinegar 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Apple Cider Vinegar 11 references
  1. Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
  2. Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
  3. Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol 2007;7:46. PubMed
  4. Johnston CS, Kim CM, Buller AJ. Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes. Diabetes Care 2004;27:281-2. PubMed
  5. Lhotta, K., Hofle, G., Gasser, R., and Finkenstedt, G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80(2):242-243. PubMed
  6. Bunick CG, Lott JP, Warren CB, et al. Chemical burn from topical apple cider vinegar. J Am Acad Dermatol 2012;67(4):e143-4. PubMed
  7. Feldstein S, Afshar M, Krakowski AC. Chemical Burn from Vinegar Following an Internet-based Protocol for Self-removal of Nevi. J Clin Aesthet Dermatol. 2015 Jun;8(6):50.
  8. Luu LA, Flowers RH, Kellams AL, et al. Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity. Pediatr Dermatol. 2019;36(5):634-639. PubMed
  9. Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC Complement Med Ther 2021;21(1):179. PubMed
  10. Feise NK, Johnston CS. Commercial vinegar tablets do not display the same physiological benefits for managing postprandial glucose concentrations as liquid vinegar. J Nutr Metab 2020;2020:9098739. PubMed
  11. Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh A. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized contro

See these in context on the Apple Cider Vinegar monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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