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Dietary supplement

Pure Inositol Pharma Grade Powder Ingredients & Drug Interactions

by HARD RHINO

Pure Inositol Pharma Grade Powder label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure Inositol Pharma Grade Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure Inositol Pharma Grade Powder is a dietary supplement by HARD RHINO with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pure Inositol Pharma Grade Powder by HARD RHINO

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Inositol Pharma Grade Powder by HARD RHINO — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pure Inositol Pharma Grade Powder by HARD RHINO

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: inositol, a naturally occurring compound related to B vitamins. Inositol plays a role in cell signaling and glucose metabolism in your body.

The rest is the powder form itself — no added fillers or binders are listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Inositol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: sleep support and anxiety control.
  • We looked for evidence on: Anxiety, Insomnia, Panic disorder, mood regulation, stress.
  • The closest evidence on file: Inositol is rated "Possibly Ineffective" for Acute respiratory distress syndrome (ARDS) (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Ineffective" for Anxiety.
  • Also on file: Inositol is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Panic disorder, Post-traumatic stress disorder (PTSD).

Inositol has possibly effective evidence for polycystic ovary syndrome (PCOS) and metabolic syndrome, meaning some clinical research supports its use but more data would strengthen the case. It's also possibly effective for preventing preterm labor.

However, the evidence doesn't support its use for anxiety, diabetic nerve pain (neuropathy), or depression — these are rated possibly ineffective based on the research we hold.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated at typical doses. The most common side effects when taken by mouth are diarrhea, gas, and nausea — usually mild and digestive in nature.

In clinical research, inositol combined with omega-3 fatty acids has been linked to cold and allergy symptoms in children. Safety in pregnancy hasn't been fully established, so if you're pregnant or planning to become pregnant, use it only under your doctor's supervision.

There isn't enough data to know about use while breastfeeding — check with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check with your doctor or pharmacist if you take any antidiabetes drugs — the Moderate-severity interaction with these medications means inositol could push your blood sugar too low when combined with them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you have PCOS, metabolic syndrome, or are at risk for preterm labor, inositol may be worth discussing with your doctor. If you take antidiabetes medication, you'll need to check with your own doctor or pharmacist before starting it, since there's a theoretical risk of low blood sugar.

Pregnant or breastfeeding? Same conversation with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Inositol Pharma Grade Powder, straight from the product label.

Brand HARD RHINO
Net contents 500 Gram(s); 1.1 lb
Market status On market
Date entered into DSLD Jun 25, 2014
DSLD ID 34521
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Inositol Pharma Grade Powder by HARD RHINO, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
1000
IngredientAmount% DV
Inositol500 mg--

Other ingredients: Inositol, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

No added fillers No flow agents No driers No other ingredients

Allergens: This product contains NO Soy, Milk & Byproducts, Eggs, Fish, Shellfish, Wheat, Gluten, Tree Nuts, or Sesame Seeds.

Suggested/Recommended/Usage/Directions

Suggested use: The commonly recommended dose for Inositol can be as little as 500 milligrams to as much as 12 grams or more per day. Use 1 to 3 grams daily as a sleep and more for controlling anxiety. For reference, one teaspoon is approximately 5 grams.

Suggested Use: As a dietary supplement, take 500mg daily or as directed by your physician.

Storage

Storage: Store in a cool and dry place. Keep away from strong light and heat.

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

WARNING: A scale is required for accurate measurements.

Keep away from children.

Do not take this or any other supplement if you are pregnant or nursing.

Do not take if you have high blood pressure or any medical complications.

Do not take this or any other supplement if you are pregnant or nursing, have high blood pressure or taking other prescription drugs.

General Statements

Always consult with your physician before taking any new dietary supplements. Expiration date on back of pouch.

USP-FCC

This is a NON-GMO ingredient produced with organic material.

Always consult with a physician before taking any new dietary supplement.

Quality Healthcare Worldwide

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure Inositol Pharma Grade Powder by HARD RHINO label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure Inositol Pharma Grade Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure Inositol Pharma Grade Powder by HARD RHINO

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container1000 Amounts shown are per serving.

Inositol

Interacts with
86 drugs
500 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

Other (inactive) ingredients: Inositol, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure Inositol Pharma Grade Powder by HARD RHINO Drug Interactions

Want to check YOUR meds against Pure Inositol Pharma Grade Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Inositol 86

Individual Drug Interactions

The ingredients in Pure Inositol Pharma Grade Powder interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pure Inositol Pharma Grade Powder interact with drugs. Each result below shows which ingredient is responsible. Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Inositol Pharma Grade Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure Inositol Pharma Grade Powder, from the product label.

HARD RHINO

Name
GUARDIAN Biosciences
City
Phoenix
State
Arizona
Pharmacist Counseling Corner

Pure Inositol Pharma Grade Powder by HARD RHINO: Common Questions

Does Pure Inositol Pharma Grade Powder by HARD RHINO interact with any medications?
Yes. Based on its ingredients, Pure Inositol Pharma Grade Powder has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Inositol Pharma Grade Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does inositol actually work for PCOS?
The evidence says possibly effective — meaning clinical research shows promise, but we'd like to see more data. Many people with PCOS do try it, especially for managing blood sugar and hormonal balance. Your doctor can help you decide if it's right for your situation.
What are the side effects?
Most people tolerate inositol well. The common ones when taken by mouth are mild: diarrhea, gas, and nausea. These usually settle down or are manageable.
Is inositol safe during pregnancy?
The safety data isn't complete yet — it's rated possibly safe, meaning it's sometimes studied in pregnant people, but we don't have enough information to call it fully safe. Talk with your doctor or midwife before taking it if you're pregnant or planning to become pregnant.
What is inositol actually for?
Inositol is a compound related to B vitamins that helps your cells send signals and manage glucose. That's why it's studied for blood sugar issues like PCOS and metabolic syndrome. Your body can make some on its own, but supplements deliver a concentrated dose.
Can I take inositol if I'm on insulin or metformin?
Not without checking with your doctor first. Inositol lowers blood sugar, and combining it with diabetes medications could lower it too much. Your doctor might still say yes, but they'll want to keep a close eye on your blood sugar levels.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Inositol Pharma Grade Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Inositol Pharma Grade Powder label
Go deeper

The Full Monographs Behind Pure Inositol Pharma Grade Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Pure Inositol Pharma Grade Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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