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Dietary supplement

Pure Chlorella Broken Cell Powder Ingredients & Drug Interactions

by HARD RHINO

Pure Chlorella Broken Cell Powder label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure Chlorella Broken Cell Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure Chlorella Broken Cell Powder is a dietary supplement by HARD RHINO with 1 active ingredient. Its ingredients are commonly taken for general nutrition and 'detox' support, immune support, liver and kidney support.Based on those ingredients, 337 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorella. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pure Chlorella Broken Cell Powder by HARD RHINO

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Chlorella Broken Cell Powder by HARD RHINO — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pure Chlorella Broken Cell Powder by HARD RHINO

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: chlorella, a single-celled green alga. It's sold here as a broken cell powder, which means the cell walls have been disrupted to make the nutrients inside easier for your body to absorb.

The inactive ingredient is the chlorella broken cell powder itself.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Chlorella's overall clinical evidence instead.

Moderate

Some clinical evidence supports Chlorella for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Pregnancy-related iron deficiency — rated "Possibly Effective" (Natural Medicines).

The evidence for chlorella is mixed and sparse. It's rated possibly effective for pregnancy-related iron deficiency — so it may help, but the data aren't robust.

For brain tumors, depression, nonalcoholic fatty liver disease (NAFLD), and fatigue, we don't have enough reliable evidence to say whether it works or doesn't. If you're thinking about trying it for any of these conditions, talk it over with your doctor first so you can weigh what little evidence exists against the potential risks.

The evidence, ingredient by ingredient Chlorella

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chlorella is generally well tolerated in the short term, but here's the catch: product quality and purity vary widely, so what you're actually getting can differ from bottle to bottle. There isn't enough safety data to recommend it unless your doctor specifically approves it.

The most common side effects are allergic reactions (including asthma in rare cases), abdominal cramping, constipation, diarrhea, fatigue, gas, nausea, photosensitivity, and green-tinted stools — especially in the first two weeks. A rare but serious reaction is anaphylaxis.

Pregnancy is rated possibly safe, but lactation data aren't on file. If you're pregnant or breastfeeding, check with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient Chlorella

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chlorella.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 337 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using this product if you take warfarin (Coumadin) or any other blood thinner — chlorella's vitamin K content can reduce how well they work. Also flag any medications that make you sun-sensitive, since chlorella might add to that risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Chlorella might help with pregnancy-related iron deficiency, but the evidence for other uses is too weak to count on. The bigger issue is interactions with blood thinners and sun-sensitizing drugs, plus the fact that product quality isn't consistent.

If you take warfarin or medications that increase sun sensitivity, don't start chlorella without clearing it with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Chlorella Broken Cell Powder, straight from the product label.

Brand HARD RHINO
Net contents 500 Gram(s); 1.1 lb
Market status On market
Date entered into DSLD Jun 25, 2014
DSLD ID 34286
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Chlorella Broken Cell Powder by HARD RHINO, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3000 mg
Maximum serving Sizes:
3000 mg
Servings per container
166
IngredientAmount% DV
Chlorella3000 mg--

Other ingredients: Chlorella Broken Cell Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Quality Healthcare Worldwide

Always consult with a physician before taking any new dietary supplement.

Always consult with your physician before taking any new dietary supplements.

Expiration date on back of pouch.

USP-FCC

This is a NON-GMO ingredient produced with organic material.

Precautions

Do not take this or any other supplement if you are pregnant or nursing, have high blood pressure or taking other prescription drugs.

WARNING: A scale is required for accurate measurements.

Keep away from children.

Do not take this or any other supplement if you are pregnant or nursing.

Do not take if you have high blood pressure or any medical complications.

WARNING: A micro scale is required for accurate measurements.

Formulation

No added fillers No flow agents No driers No other ingredients

Allergens: This product contains NO Soy, Milk & Byproducts, Eggs, Fish, Shellfish, Wheat, Gluten, Tree Nuts, or Sesame Seeds.

Suggested/Recommended/Usage/Directions

Suggested Use: A common dosage is about 3000 mg 1-3 times daily, mixed with juice, water, smoothie, ect. Try to avoid mixing with hot liquids or foods as this may reduce efficacy.

Suggested Use: As a dietary supplement take 3000 mg doses, 1 to 3 times daily as needed, preferably mixed with juice or shakes.

Storage

Storage: Store in a cool & dry place. Keep away from strong light & heat.

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure Chlorella Broken Cell Powder by HARD RHINO label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure Chlorella Broken Cell Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure Chlorella Broken Cell Powder by HARD RHINO

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3000 mg Dosage formPowder Servings per container166 Amounts shown are per serving.

Chlorella

Interacts with
337 drugs
3000 mg per serving

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies sugges...

Chlorella monograph & interactions

Other (inactive) ingredients: Chlorella Broken Cell Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure Chlorella Broken Cell Powder by HARD RHINO Drug Interactions

Want to check YOUR meds against Pure Chlorella Broken Cell Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
337Drugs
337 Moderate

Ingredients driving the most interactions

Chlorella 337

Individual Drug Interactions

The ingredients in Pure Chlorella Broken Cell Powder interact with 337 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pure Chlorella Broken Cell Powder interact with drugs. Each result below shows which ingredient is responsible. Chlorella

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Chlorella Broken Cell Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorella2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D
Chlorella full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure Chlorella Broken Cell Powder, from the product label.

HARD RHINO

Name
GUARDIAN Biosciences
City
Phoenix
State
Arizona
Pharmacist Counseling Corner

Pure Chlorella Broken Cell Powder by HARD RHINO: Common Questions

Does Pure Chlorella Broken Cell Powder by HARD RHINO interact with any medications?
Yes. Based on its ingredients, Pure Chlorella Broken Cell Powder has a known interaction with 337 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Chlorella Broken Cell Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
Not without talking to your doctor first. Chlorella is high in vitamin K, which can make warfarin less effective. There's at least one documented case of someone's blood-thinning therapy failing after starting chlorella, so this one needs professional clearance.
What are the most common side effects?
Digestive upset — cramping, diarrhea, constipation, gas, and nausea — is most common, especially in the first two weeks. You might also see allergic reactions, fatigue, sun sensitivity, and green-tinted stools. Serious reactions like anaphylaxis are rare.
Is this safe during pregnancy?
Pregnancy is rated possibly safe, which means there's some suggestion it might be okay, but we don't have enough data to be sure. Talk with your doctor or pharmacist for personalized advice — don't start it on your own.
Does chlorella actually work for iron deficiency in pregnancy?
It's rated possibly effective, which means the evidence suggests it might help — but it's not strong. If you're pregnant and iron-deficient, your doctor or midwife can tell you whether chlorella is worth trying alongside other treatments.
Why does the label say product quality varies widely?
Chlorella supplements aren't as tightly regulated as pharmaceuticals, so purity and potency can differ between brands and even between batches. That's why it matters to buy from a trusted source and stay consistent.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Chlorella Broken Cell Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Chlorella Broken Cell Powder label
Go deeper

The Full Monographs Behind Pure Chlorella Broken Cell Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chlorella

Interacts with 337 drugs

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies suggest possible benefits for cholesterol, blo...

Read the full Chlorella monograph →
Sources

Sources & How We Checked

Pure Chlorella Broken Cell Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chlorella 13 references
  1. Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
  2. Ng TP, Tan WC, Lee YK. Occupational asthma in a pharmacist induced by chlorella, a unicellular algae preparation. Resp Med 1994;88:555-7. PubMed
  3. Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol 1984;23:263-8. PubMed
  4. Merchant RE, Carmack CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother Res 2000;14:167-73.
  5. Merchant RE, Rice CD, Young HF. Dietary Chlorella pyrenoidosa for patients with malignant glioma: effects on immunocompetence, quality of life, and survival. Phytother Res 1990;4:220-31.
  6. Halperin SA, Smith B, Nolan C, et al. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ 2003;169:111-7..
  7. Ohtake, T., Negishi, K., Okamoto, K., Oka, M., Maesato, K., Moriya, H., and Kobayashi, S. Manganese-induced Parkinsonism in a patient undergoing maintenance hemodialysis. Am J Kidney Dis 2005;46(4):749-753. PubMed
  8. Ng, T. P., Tan, W. C., and Lee, Y. K. Occupational asthma in a pharmacist induced by Chlorella, a unicellular algae preparation. Respir.Med. 1994;88(7):555-557. PubMed
  9. Ohkawa, S., Yoneda, Y., Ohsumi, Y., and Tabuchi, M. [Warfarin therapy and chlorella]. Rinsho Shinkeigaku 1995;35(7):806-807.
  10. Azocar J, Diaz A. Efficacy and safety of chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol 2013;19(7):1085-90. PubMed
  11. Panahi Y, Badeli R, Karami GR, Badeli Z, Sahebkar A. A randomized controlled trial of 6-week Chlorella vulgaris supplementation in patients with major depressive disorder. Complement Ther Med 2015;23(4):598-602. PubMed
  12. Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr 2010;65(1):25-30. PubMed
  13. Yavasoglu I, Turgutkaya A, Bolaman Z. Chlorella-induced thrombocytopenia. Sao Paulo Med J 2018;136(6):602-3. PubMed

See these in context on the Chlorella monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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