Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Quadra Lean Ingredients & Drug Interactions

by RSP

Quadra Lean label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Quadra Lean against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Quadra Lean is a dietary supplement by RSP with 6 active ingredients. Its ingredients are commonly taken for weight loss, fat burning, boosting metabolism.Based on those ingredients, 792 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Garcinia cambogia extract, Acetyl-L-Carnitine HCl, Raspberry Ketones. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Quadra Lean by RSP

Ask about any prescription or over-the-counter medication and we check it for interactions with Quadra Lean by RSP — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Quadra Lean by RSP

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 6 active ingredients.
  • “QuadraLean(TM) Carnitine Blend” is a proprietary blend — the label gives one combined amount (500 mg) without saying how much of each component you get.

Quadra Lean contains 6 active ingredients. Three are carnitine compounds—L-Carnitine L-Tartrate, Acetyl-L-Carnitine HCl, and Propionyl-L-Carnitine HCl—which work to support cellular energy production and fat metabolism.

The product also includes Garcinia cambogia extract (which supplies hydroxycitric acid), Raspberry Ketones, and Clarinol. The remaining ingredients are inactive: gelatin, plant cellulose, silicon dioxide, and magnesium stearate, which serve as the capsule material and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: weight loss and metabolic support.
  • We looked for evidence on: Athletic performance, Cachexia, Cardiovascular disease (CVD), Chronic fatigue syndrome (CFS), Cognitive function, Coronary heart disease (CHD) — and 4 related terms.
  • The strongest evidence on file: Propionyl-l-carnitine is rated "Possibly Effective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Propionyl-l-carnitine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Chronic fatigue syndrome (CFS).
  • Also on file: Garcinia is rated "Insufficient Reliable Evidence To Rate" for Athletic performance.

Evidence for these ingredients is limited. The carnitine forms are effective for treating carnitine deficiency but are only possibly effective for heart failure, angina, and high cholesterol—meaning the research shows promise but isn't conclusive.

Garcinia and Raspberry Ketones show insufficient reliable evidence to rate for obesity and athletic performance, so we don't know whether they work for weight loss at the doses in this product. Acetyl-L-Carnitine is possibly effective for age-related cognitive decline, Alzheimer's disease, diabetic nerve pain, and depression, though again the evidence isn't definitive.

The evidence, ingredient by ingredient Raspberry Ketone Garcinia L-carnitine Acetyl-l-carnitine Propionyl-l-carnitine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The carnitine ingredients are generally well tolerated, though high doses can cause stomach upset, nausea, diarrhea, abdominal pain, and a fishy body odor. A rare serious side effect is seizures.

Acetyl-L-Carnitine may cause agitation, dry mouth, headache, insomnia, and reduced appetite. Garcinia is generally tolerated short-term, but rare reports link it to liver injury, mania, and pancreatitis.

Raspberry Ketones structurally resemble a stimulant and have been linked to heart palpitations, elevated blood pressure, and dangerous heart rhythms in case reports, though human safety data is very limited. Pregnancy: avoid Raspberry Ketones and Garcinia; safety data for L-Carnitine in pregnancy is absent.

Lactation: L-Carnitine is possibly safe; avoid Raspberry Ketones and Garcinia; safety for Acetyl-L-Carnitine and Propionyl-L-Carnitine while breastfeeding is unknown.

Side effects, ingredient by ingredient Raspberry Ketone Garcinia L-carnitine Acetyl-l-carnitine Propionyl-l-carnitine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Propionyl-l-carnitine, Garcinia, Acetyl-l-carnitine, L-carnitine, Raspberry Ketone.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 793 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this list before taking Quadra Lean: blood thinners (warfarin, acenocoumarol), thyroid hormone replacement, stimulant drugs (including some decongestants and ADHD medications), serotonergic drugs (antidepressants like SSRIs), antiplatelet or anticoagulant drugs, and diabetes medications. If you take any of these, use the medication checker below or speak with your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a multi-ingredient weight-management and energy supplement aimed at people interested in fat metabolism and endurance. If you take blood thinners, thyroid replacement, antidepressants, stimulants, diabetes medications, or any drug that affects the liver, talk to your pharmacist before starting—the interactions are real and may require dose adjustments.

The evidence for weight loss is weak, and some ingredients carry rare but serious cardiovascular risks. It's not appropriate during pregnancy or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Quadra Lean, straight from the product label.

Brand RSP
Barcode (UPC) 852113002729
Net contents 150 Capsule(s)
Market status On market
Date entered into DSLD Aug 25, 2015
DSLD ID 49521
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Quadra Lean by RSP, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
50
UPC/BARCODE
852113002729
IngredientAmount% DV
L-Carnitine L-Tartrate0 NP--
Raspberry Ketones250 mg--
Acetyl-L-Carnitine HCl0 NP--
Garcinia cambogia extract500 mg--
Propionyl-L-Carnitine HCl0 NP--
Clarinol(R)500 mg--
QuadraLean(TM) Carnitine Blend500 mg--

Other ingredients: Gelatin, Cellulose, Plant, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

QuadraLean(TM) is a 100% stimulant free weight loss solution scientifically formulated to target and control the 4 key factors of weight loss: Appetite, Fat Storage, Energy & Metabolism.

Formula

QuadraLean(TM) contains effective dosages of 4 primary ingredients that control the 4 factors of weight loss. These 4 primary ingredients are: >CLA (Conjugated Linoleic Acid) (Clarinol(R)): ~Supports the breakdown of body fat ~Helps reduce the number of fat cells in the body >L-Carnitine: ~Helps convert fat into usable energy for the body ~Supports increased metabolism >Raspberry Ketones: ~ Decreases the absorption of fat ~ Supports thermogenesis in brown adipose tissue (bad fat) >Garcinia Cambogia: ~Supports appetite control & mood enhancement ~Limits enzyme production that turn carbohydrates to fat

Seals/Symbols

{Flag} Made in the USA

RSP Nutrition

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

If you have any health condition, are pregnant, breast feeding or taking medication, ask a physician before use.

Keep out of reach of small children.

General Statements

Stimulant free weight loss

Increase endurance Build muscle Burn fat Recover faster

50 Servings

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 3 capsules on an empty stomach twice daily or as recommended by healthcare practitioner. Do not exceed 6 capsules in a 24 hour period.

Brand IP Statement(s)

QuadraLean:(TM) The Science

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Quadra Lean by RSP label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Quadra Lean label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Quadra Lean by RSP

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Raspberry Ketones

Interacts with
174 drugs
250 mg per serving

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence th...

Raspberry Ketones monograph & interactions

Garcinia cambogia extract

Interacts with
704 drugs
500 mg per serving

Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific eviden...

Garcinia cambogia extract monograph & interactions

Clarinol(R)

500 mg per serving Form: Conjugated Linoleic Acid

QuadraLean(TM) Carnitine Blend

500 mg per serving

Other (inactive) ingredients: Gelatin, Cellulose, Plant, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Quadra Lean by RSP Drug Interactions

Want to check YOUR meds against Quadra Lean?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
792Drugs
792 Moderate

Ingredients driving the most interactions

Garcinia cambogia extract 704
Acetyl-L-Carnitine HCl 203
Raspberry Ketones 174
L-Carnitine L-Tartrate 19
Propionyl-L-Carnitine HCl 19

Individual Drug Interactions

The ingredients in Quadra Lean interact with 792 drugs. Click any drug to see the details.

5 of the 6 ingredients in Quadra Lean interact with drugs. Each result below shows which ingredient is responsible. Garcinia cambogia extract Acetyl-L-Carnitine HCl Raspberry Ketones L-Carnitine L-Tartrate Propionyl-L-Carnitine HCl

Each ingredient & the kinds of drugs it affects

For each ingredient in Quadra Lean with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Garcinia cambogia extract4 drug types · 704 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.

Likelihood Possible Evidence D
Serotonergic Drugs

Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.

Likelihood Possible Evidence D
Garcinia cambogia extract full monograph & interactions

Acetyl-L-Carnitine HCl4 drug types · 203 drugs

Acenocoumarol (Sintrom)

Theoretically, acetyl-L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine, the parent compound of acetyl-L-carnitine, might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant that is similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation when L-carnitine was taken with acenocoumarol. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product. It is unclear if such an interaction would also occur with acetyl-L-carnitine.

Likelihood Possible Evidence D
Serotonergic Drugs

Theoretically, acetyl-L-carnitine might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders, when taken with serotonergic drugs.
Animal research shows that acetyl-L-carnitine can increase levels of serotonin in the brain.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, acetyl-L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism. It is unclear if such an interaction would occur with acetyl-L-carnitine.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, acetyl-L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine, the parent compound of acetyl-L-carnitine, might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with acetyl-L-carnitine and warfarin.

Likelihood Possible Evidence D
Acetyl-L-Carnitine HCl full monograph & interactions

Raspberry Ketones2 drug types · 174 drugs

Stimulant Drugs

Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Structurally, raspberry ketone resembles synephrine, a known stimulant agent. Heart palpitations, elevated blood pressure, coronary vasospasm, pulseless electrical activity arrest, and resistant polymorphic ventricular tachycardia have been reported in patients taking raspberry ketone.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, raspberry ketone might increase warfarin dose requirements.
In one case report, a patient taking warfarin 55 mg per week had a decrease in INR over a period of one month while taking raspberry ketone 250 mg daily. A warfarin dose increase to 70 mg per week was necessary to maintain a therapeutic INR while taking raspberry ketone. The mechanism for this potential interaction is not known.

Likelihood Possible Evidence D
Raspberry Ketones full monograph & interactions

L-Carnitine L-Tartrate3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine L-Tartrate full monograph & interactions

Propionyl-L-Carnitine HCl3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, propionyl-L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine, the parent compound of propionyl-L-carnitine, might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation when L-carnitine was taken with acenocoumarol. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product. It is unclear if such an interaction would also occur with propionyl-L-carnitine.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, acetyl-L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism. It is unclear if such an interaction would occur with propionyl-L-carnitine.

Likelihood Possible Evidence B
Warfarin (Coumadin)

Theoretically, propionyl-L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine, the parent compound of propionyl-L-carnitine, might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with propionyl-L-carnitine and warfarin.

Likelihood Possible Evidence D
Propionyl-L-Carnitine HCl full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Quadra Lean, from the product label.

RSP

See all RSP products
Name
RSP Nutrition
Street Address
PO Box 398776
City
Miami Beach
State
FL
ZipCode
33239
Phone Number
877-814-2544
Web Address
www.rspnutrition.com
Pharmacist Counseling Corner

Quadra Lean by RSP: Common Questions

Does Quadra Lean by RSP interact with any medications?
Yes. Based on its ingredients, Quadra Lean has a known interaction with 792 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Quadra Lean contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Quadra Lean help me lose weight?
The main ingredients—Garcinia and Raspberry Ketones—don't have enough reliable evidence to prove they work for weight loss. The carnitine compounds are effective for carnitine deficiency but are only possibly effective for related metabolic conditions. You'd need to verify this works for you rather than assume the label claim.
What's the fishy smell I might notice?
The carnitine ingredients (L-Carnitine, Acetyl-L-Carnitine, and Propionyl-L-Carnitine) can produce a metabolite that causes a fish-like odor in urine, breath, and sweat. It's harmless but can be noticeable at higher doses.
Can I take this if I'm pregnant or breastfeeding?
No, not safely based on current data. Raspberry Ketones and Garcinia should be avoided during pregnancy and lactation—there isn't enough safety information. L-Carnitine safety during pregnancy is unknown, so you'd need to talk with your doctor or midwife first. While breastfeeding, L-Carnitine is possibly safe, but the other ingredients carry too much uncertainty.
What side effects should I watch for?
Most common are stomach upset, nausea, diarrhea, and abdominal discomfort from the carnitine compounds. Acetyl-L-Carnitine may cause agitation, insomnia, or headache. Raspberry Ketones and Garcinia carry rarer but more serious risks: heart palpitations, elevated blood pressure, and (very rarely) liver injury or mood changes. Stop and contact your doctor if you develop chest pain, shortness of breath, or unusual bruising.
Does it interact with my antidepressant?
Possibly. Both Garcinia and Acetyl-L-Carnitine may increase serotonergic side effects when combined with antidepressants, raising the theoretical risk of serotonin syndrome (agitation, confusion, rapid heart rate, fever). Use the medication checker on this page or ask your pharmacist before starting.
I take warfarin for blood clots. Is Quadra Lean safe?
No, not without close monitoring. Multiple ingredients in this product—all three carnitine forms and Raspberry Ketones—may increase warfarin's blood-thinning effects or change how much warfarin you need. Talk to your doctor or pharmacist before taking it; your INR (blood clot measure) would need to be checked more often.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Quadra Lean label
Go deeper

The Full Monographs Behind Quadra Lean’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Raspberry Ketone

Interacts with 174 drugs

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence that it helps people lose weight. Most cla...

Read the full Raspberry Ketone monograph → Herb & supplement monograph

Garcinia

Interacts with 704 drugs

Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific evidence is weak and mixed, with most studies...

Read the full Garcinia monograph → Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph → Herb & supplement monograph

Acetyl-l-carnitine

Interacts with 203 drugs

Acetyl-L-carnitine is a form of the amino acid carnitine that the body uses to help produce energy in cells. It is most studied for nerve pain and memory-related conditions, though the evide...

Read the full Acetyl-l-carnitine monograph → Herb & supplement monograph

Propionyl-l-carnitine

Interacts with 19 drugs

Propionyl-l-carnitine is a form of the amino acid derivative carnitine that the body uses to help turn fat into energy, and it is studied mostly for circulation problems like peripheral arte...

Read the full Propionyl-l-carnitine monograph →
Sources

Sources & How We Checked

Quadra Lean's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 123 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-carnitine 41 references
  1. Ellaway CM, Williams K, Leonard H, et al. Rett syndrome: randomized controlled trial of L-carnitine. J Child Neurol 1999;14:162-7. PubMed
  2. Anon. Carnitor (levocarnitine) package insert. Sigma-Tau Pharmaceuticals Inc, Gaithersburg, MD. December 1999.
  3. Cherchi A, Lai C, Angelino F, et al. Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo-controlled, crossover study. Int J Clin Pharmacol Ther Toxicol 1985;23:569-72.
  4. Plioplys AV, Plioplys S. Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. Neuropsychobiology 1997;35:16-23. PubMed
  5. Benvenga S, Ruggeri RM, Russo A, et al. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Meta
  6. Martinez E, Domingo P, Roca-Cusachs A. Potentiation of acenocoumarol action by L-carnitine. J Intern Med 1993;233:94.
  7. Bachmann HU, Hoffmann A. Interaction of food supplement L-carnitine with oral anticoagulant acenocoumarol. Swiss Med Wkly 2004;134:385. PubMed
  8. Evans AM, Fornasini G. Pharmacokinetics of L-carnitine. Clin Pharmacokinet 2003;42:941-67. PubMed
  9. 12761 Benvenga S, Amato A, Calvani M, Trimarchi F. Effects of carnitine on thyroid hormone action. Ann N Y Acad Sci 2004;1033:158-67. PubMed
  10. Ciacci C, Peluso G, Iannoni E, et al. L-Carnitine in the treatment of fatigue in adult celiac disease patients: a pilot study. Dig Liver Dis 2007;39:922-8. PubMed
  11. Cruciani RA, Dvorkin E, Homel P, et al. Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. J Pain Symptom Manage 2006;32:551-9. PubMed
  12. Lebrun C, Alchaar H, Candito M, et al. Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue. Mult Scler 2006;12:321-4. PubMed
  13. Malaguarnera M, Cammalleri L, Gargante MP, et al. L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial. Am J Clin Nutr 2007;86:1738-44. PubMed
  14. Mantovani G, Maccio A, Madeddu C, et al. Randomized phase III clinical trial of five different arms of treatment in 322 patients with cancer cachexia. Oncologist 2010;15:200-11.
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Raspberry Ketone 4 references
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Acetyl-l-carnitine 22 references
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Garcinia 44 references
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Propionyl-l-carnitine 12 references
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  2. Bartels GL, Remme WJ, den Hartog FR, et al. Additional anti-ischemic effects of long-term L-propionylcarnitine in anginal patients treated with conventional antianginal therapy. Cardiovasc Drugs Ther 1995;9:749-53.
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