Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Quick Brain Nootropic Ingredients & Drug Interactions

by Life Extension

Quick Brain Nootropic label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Quick Brain Nootropic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Quick Brain Nootropic is a dietary supplement by Life Extension with 4 active ingredients. Its ingredients are commonly taken for wound healing, varicose veins and poor circulation, anxiety and stress.Based on those ingredients, 1,192 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BaCognize Ultra Bacopa extract, Gotu Kola extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Quick Brain Nootropic by Life Extension

Ask about any prescription or over-the-counter medication and we check it for interactions with Quick Brain Nootropic by Life Extension — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Quick Brain Nootropic by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Quick Brain Nootropic contains 4 active ingredients. Gotu kola extract and bacopa extract (the trademarked BaCognize Ultra form) are the primary components; both have been used traditionally to support cognitive function.

The product also includes two marigold extracts: FloraGLO Marigold extract and plain Marigold extract. The capsules also contain inactive ingredients—microcrystalline cellulose, vegetable cellulose, maltodextrin, modified starch, starch, and silica—which serve as binders and fillers.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: memory and cognitive brain health.
  • We looked for evidence on: Cognitive function, Cognitive impairment, Attention deficit-hyperactivity disorder (ADHD), Wound healing, memory decline, mental clarity — and 1 related terms.
  • The closest evidence on file: Gotu Kola is rated "Possibly Ineffective" for Cognitive function (Natural Medicines).
  • Also on file: Gotu Kola is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Wound healing.
  • Also on file: Bacopa is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function, Cognitive impairment.

The evidence for this product's ingredients on brain function is limited. Bacopa and gotu kola are both rated with insufficient reliable evidence for cognitive function and Alzheimer disease.

Gotu kola shows possibly effective evidence only for venous insufficiency and burns, with possibly ineffective evidence for radiation dermatitis. The marigold extracts have no effectiveness ratings on file.

If you're looking for established cognitive support, the data we hold does not confirm that these ingredients deliver it.

The evidence, ingredient by ingredient Gotu Kola Bacopa Tagetes

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gotu kola is generally well tolerated short-term, but long-term safety data are thin and there are rare reports of liver toxicity—though it's unclear whether gotu kola was the cause in those cases. Most common side effects are gastric irritation and nausea.

Bacopa is also generally well tolerated in studies, though gastrointestinal side effects (abdominal cramps, diarrhea, nausea, bloating) occur in a small number of users, and some have reported drowsiness or insomnia. The marigold extracts are considered low-risk in food amounts, though topical use can cause contact dermatitis.

Pregnancy and breastfeeding data are scarce. Gotu kola is rated possibly safe in pregnancy but should be avoided while breastfeeding due to unknown safety.

Bacopa and the marigold extracts lack enough safety information—the data advises against medicinal use in both pregnancy and breastfeeding. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Gotu Kola Bacopa Tagetes

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Gotu Kola, Bacopa.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1,193 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check your medications with your doctor or pharmacist if you take hepatotoxic drugs (drugs that can damage the liver), CNS depressants (sedatives, sleep aids, pain relievers), anticholinergic or cholinergic drugs, drugs metabolized by liver enzymes (CYP1A2, CYP2C19, CYP2C9, or CYP3A4 substrates), cevimeline for Sjogren syndrome, or thyroid hormone. Altogether, these interactions span 1,193 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Quick Brain Nootropic is built on two traditional cognitive herbs, but the evidence that they work for that purpose isn't solid. More importantly, both gotu kola and bacopa interact with medications through multiple pathways.

If you take prescription drugs—especially those for the liver, central nervous system, brain, or thyroid—have your doctor or pharmacist review your medication list against this product before you start. Pregnant or breastfeeding women should check with their healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Quick Brain Nootropic, straight from the product label.

Brand Life Extension
Barcode (UPC) 737870240600
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 233011
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Quick Brain Nootropic by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
737870240600
IngredientAmount% DV
Gotu Kola extract250 mg--
BaCognize Ultra Bacopa extract150 mg--
FloraGLO Marigold extract100 mg--
Marigold extract52 mg--

Other ingredients: Microcrystalline Cellulose, Vegetable Cellulose, Maltodextrin, Starch-modified, Starch, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) capsule daily, or as recommended by a healthcare practitioner.

1 daily

Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Warning: Reproductive Harm - www.P65Warnings.ca.gov.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

BACOGNIZE ULTRA is a registered trademark of Verdure Sciences, Inc. FloraGLO is a registered trademark of Kemin Industries, Inc.

Formulation

Gluten free

Non GMO LE Certified

Enhanced neural processing, learning and retention

Seals/Symbols

Non GMO LE Certified

FDA Statement of Identity

Dietary Supplement

Storage

Store tightly closed in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Quick Brain Nootropic by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Quick Brain Nootropic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Quick Brain Nootropic by Life Extension

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Gotu Kola extract

Interacts with
579 drugs
250 mg per serving Form: Asiaticosides

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...

Gotu Kola extract monograph & interactions

BaCognize Ultra Bacopa extract

Interacts with
930 drugs
150 mg per serving Form: Bacopa Glycosides

Bacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for s...

BaCognize Ultra Bacopa extract monograph & interactions

FloraGLO Marigold extract

No known
interactions
100 mg per serving Form: Lutein, Zeaxanthin

Tagetes (marigold) is a group of flowering plants used in traditional medicine and as a source of plant pigments like lutein. Human evidence for most...

FloraGLO Marigold extract monograph & interactions

Marigold extract

No known
interactions
52 mg per serving Form: Zeaxanthin

Tagetes (marigold) is a group of flowering plants used in traditional medicine and as a source of plant pigments like lutein. Human evidence for most...

Marigold extract monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Vegetable Cellulose, Maltodextrin, Starch-modified, Starch, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Quick Brain Nootropic by Life Extension Drug Interactions

Want to check YOUR meds against Quick Brain Nootropic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,192Drugs
1,179 Moderate 13 Minor

Ingredients driving the most interactions

BaCognize Ultra Bacopa extract 930
Gotu Kola extract 579

Individual Drug Interactions

The ingredients in Quick Brain Nootropic interact with 1,192 drugs. Click any drug to see the details.

2 of the 4 ingredients in Quick Brain Nootropic interact with drugs. Each result below shows which ingredient is responsible. BaCognize Ultra Bacopa extract Gotu Kola extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Quick Brain Nootropic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

BaCognize Ultra Bacopa extract8 drug types · 930 drugs

Anticholinergic Drugs

Theoretically, concurrent use might decrease the effectiveness of both agents.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels, which could counteract the effects of anticholinergic drugs. Similarly, anticholinergic drugs might counteract the cholinergic effects of bacopa.

Likelihood Possible Evidence D
Cevimeline (Evoxac)

Theoretically, bacopa might increase the effects and adverse effects of cevimeline.
In one case, a 58-year-old female taking cevimeline long-term for Sjogren syndrome experienced hyperhidrosis, malaise, nausea, and tachycardia shortly after taking a single dose of bacopa. Symptoms resolved after two days. Cevimeline is metabolized by cytochrome P450 (CYP) 2D6 and CYP3A4, and researchers theorize that bacopa may have inhibited these isoenzymes. However, it is unclear if bacopa causes clinically significant inhibition of either CYP2D6 or CYP3A4.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels. Theoretically, this could result in additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Research on the effects of bacopa extracts on CYP1A2 enzymes is conflicting. Some in vitro evidence shows that bacopa extract can moderately and non-competitively inhibit CYP1A2, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
In vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C19 enzymes. It is not known whether this is clinically significant.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Research on the effect of bacopa extracts on CYP2C9 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C9, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Research on the effects of bacopa extracts on CYP3A4 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and competitively inhibit CYP3A4, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, bacopa might have additive effects when used with thyroid hormone.
Animal research suggests that bacopa increases thyroxine (T4) levels in mice by about 40%.

Likelihood Possible Evidence D
BaCognize Ultra Bacopa extract full monograph & interactions

Gotu Kola extract2 drug types · 579 drugs

Cns Depressants

Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.

Likelihood Possible Evidence D
Gotu Kola extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Quick Brain Nootropic, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

Quick Brain Nootropic by Life Extension: Common Questions

Does Quick Brain Nootropic by Life Extension interact with any medications?
Yes. Based on its ingredients, Quick Brain Nootropic has a known interaction with 1,192 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Quick Brain Nootropic contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me think more clearly?
The evidence isn't there yet. Bacopa and gotu kola are both rated with insufficient reliable evidence for cognitive function. Gotu kola is rated possibly ineffective for Alzheimer disease. If you're looking for proven cognitive support, the data we hold doesn't confirm these ingredients deliver it.
Can I take this if I'm pregnant?
Not without talking to your doctor first. Gotu kola is rated possibly safe in pregnancy, but bacopa and the marigold extracts lack enough safety data—the facts advise against their medicinal use in pregnancy. Check with your healthcare provider to discuss your individual situation.
What are the most common side effects?
Gotu kola may cause gastric irritation and nausea. Bacopa more often causes gastrointestinal upset—abdominal cramps, diarrhea, nausea, and bloating—in a small number of users. Some people also report drowsiness or insomnia with bacopa. The marigolds are generally well tolerated when taken by mouth.
Is it safe to take this with my blood pressure or heart medication?
That depends on your exact drug. Many blood pressure and heart medications are processed by liver enzymes that bacopa may affect, and some are cholinergic or anticholinergic—categories where bacopa has documented interactions. Use the interaction checker on this page with your specific medications, and confirm with your pharmacist or doctor before starting.
What is bacopa supposed to do?
Bacopa has been used traditionally to support memory and brain function, but our data shows insufficient reliable evidence for cognitive function, ADHD, or other brain-related uses. It does seem to affect how your body processes certain medications and increases acetylcholine, a brain chemical involved in memory and attention.
Can I take this while breastfeeding?
No—the facts advise against it. Gotu kola, bacopa, and both marigold extracts lack enough safety data during breastfeeding. Talk with your doctor or pharmacist about whether it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Quick Brain Nootropic label
Go deeper

The Full Monographs Behind Quick Brain Nootropic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gotu Kola

Interacts with 579 drugs

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...

Read the full Gotu Kola monograph → Herb & supplement monograph

Bacopa

Interacts with 930 drugs

Bacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for several weeks, but the evidence is limite...

Read the full Bacopa monograph → Herb & supplement monograph

Tagetes

Tagetes (marigold) is a group of flowering plants used in traditional medicine and as a source of plant pigments like lutein. Human evidence for most health benefits is very limited, and the...

Read the full Tagetes monograph →
Sources

Sources & How We Checked

Quick Brain Nootropic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gotu Kola 18 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
  3. Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
  4. Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
  5. Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
  6. Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
  7. Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
  8. Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
  9. Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
  10. Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
  11. Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
  12. Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
  13. Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
  14. Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
  15. Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
  16. Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
  17. Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
  18. Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed

See these in context on the Gotu Kola monograph →

Bacopa 12 references
  1. Stough C, Lloyd J, Clarke J, et al. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology 2001;156:481-4..
  2. Yadav SK, Jain AK, Tripathi SN, Gupta JP. Irritable bowel syndrome: therapeutic evaluation of indigenous drugs. Indian J Med Res 1989;90:496-503..
  3. Morgan A, Stevens J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. J Altern Complement Med 2010;16:753-9.
  4. Kar, A., Panda, S., and Bharti, S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. J Ethnopharmacol. 2002;81(2):281-285. PubMed
  5. Mukherjee, G. D. and Dey, C. D. Clinical trial on Brahmi. I. J.Exp.Med.Sci. 1966;10(1):5-11.
  6. Kar A, Pandit S, Mukherjee K, Bahadur S, Mukherjee PK. Safety assessment of selected medicinal food plants used in Ayurveda through CYP450 enzyme inhibition study. J Sci Food Agric 2017;97(1):333-40. doi: 10.1002/jsfa.7739. PubMed
  7. Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014;151(1):528-35. PubMed
  8. Ramasamy S, Kiew LV, Chung LY. Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents. Molecules 2014;19(2):2588-601. PubMed
  9. Prabhakar S, Vishnu VY, Modi M, et al. Efficacy of Bacopa monnieri (Brahmi) and donepezil in Alzheimer's disease and mild cognitive impairment: a randomized double-blind parallel phase 2b study. Ann Indian Acad Neurol 2020;23(6):767-73. PubMed
  10. Acquarulo B, Tandon P, Macica CM. Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report. J Med Case Rep 2022;16(1):253. PubMed
  11. Keegan AP, Stough C, Paris D, et al. Bacopa monnieri supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderl
  12. Yaworski AM, Blyumin M, Chang T, Mammen AL, Greene M. Necrotizing myopathy with elevated anti-HMGCR antibodies following exposure to the supplement Bacopa. Muscle Nerve 2023;67(2):E1-E3.

See these in context on the Bacopa monograph →

Tagetes 1 reference
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.

See these in context on the Tagetes monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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