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Dietary supplement

Raw Apple Cider Vinegar 1500 mg Ingredients & Drug Interactions

by HerbTonics

Raw Apple Cider Vinegar 1500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Raw Apple Cider Vinegar 1500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Raw Apple Cider Vinegar 1500 mg is a dietary supplement by HerbTonics with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 162 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Apple Cider Vinegar. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Raw Apple Cider Vinegar 1500 mg by HerbTonics

Ask about any prescription or over-the-counter medication and we check it for interactions with Raw Apple Cider Vinegar 1500 mg by HerbTonics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Raw Apple Cider Vinegar 1500 mg by HerbTonics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: apple cider vinegar at 1500 mg per capsule. The capsule itself is made from cellulose, an inactive filler.

Apple cider vinegar is a fermented vinegar product derived from apples. It's used as a supplement for a range of purposes, though the evidence for most claims remains limited.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Apple Cider Vinegar product and its label doesn't state a use — see Apple Cider Vinegar's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold does not establish that apple cider vinegar is effective for acne, athletic performance, cognitive function, dental plaque, depression, or atopic dermatitis (eczema). Our data rates all of these uses as having insufficient reliable evidence to rate its benefit.

If you're considering this supplement for one of these purposes, talk it over with your doctor or pharmacist about whether the current research supports your specific goal.

The evidence, ingredient by ingredient Apple Cider Vinegar

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

In food amounts, apple cider vinegar is generally well tolerated. When used orally for short-term medicinal purposes, it also seems to be well tolerated.

However, there is limited safety data on large supplement doses, and long-term use in larger amounts may be unsafe. Serious side effects are rare but have been reported with long-term heavy use: one documented case involved someone who ingested 250 mL (about 8 ounces) daily for 6 years and developed low potassium, elevated renin levels, and osteoporosis.

Topical use carries risk of chemical burns and skin irritation. Because of these concerns, avoid large medicinal or unpasteurized amounts unless your doctor approves.

Side effects, ingredient by ingredient Apple Cider Vinegar

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Apple Cider Vinegar.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 162 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take digoxin (a heart medication), diuretic drugs (water pills), insulin, or antidiabetes drugs. The first three carry Moderate interaction concerns; the last is Minor but still worth confirming.

These are the medication types we have documented interactions for with apple cider vinegar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Raw Apple Cider Vinegar 1500 mg might appeal to someone looking to experiment with a common household supplement, but the evidence for its effectiveness in treating specific conditions isn't established in our data. You should be careful if you take digoxin, diuretics, insulin, or diabetes medications—the documented interactions are real and worth discussing with your doctor or pharmacist before you start.

Talk it over with them to make sure this supplement fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Raw Apple Cider Vinegar 1500 mg, straight from the product label.

Brand HerbTonics
Barcode (UPC) X001R6KHSH
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 287066
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Raw Apple Cider Vinegar 1500 mg by HerbTonics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetable Capsule(s)
Maximum serving Sizes:
2 Vegetable Capsule(s)
Servings per container
60
UPC/BARCODE
X001R6KHSH
IngredientAmount% DV
Apple Cider Vinegar1500 mg--

Other ingredients: Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

100% Natural

Non-GMO

Helps healthy digestion Promotes detoxification Natural weight management aid Puts the body into ketosis

Gluten free Dairy free

Unfiltered

Healthy detoxifying agent Supports weight management

No fillers No additives No artificial colors or flavors, chemical preservatives, dairy, soy, or gluten

Suggested/Recommended/Usage/Directions

Instructions: As a dietary supplement, adults should take one (1) or two (2) capsules before a meal, or as directed by a physician.

Apple Cider Vinegar should always be taken in conjunction with a healthy diet and a regular exercise program.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Apple Cider Vinegar With the mother

FDA Statement of Identity

Dietary supplement

Brand IP Statement(s)

HerbTonics For a healthier you!

Seals/Symbols

FDA Registered Facility Good Manufacturing Practices GMP Certified Made in the USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Raw Apple Cider Vinegar 1500 mg by HerbTonics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Raw Apple Cider Vinegar 1500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Raw Apple Cider Vinegar 1500 mg by HerbTonics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetable Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Apple Cider Vinegar

Interacts with
162 drugs
1500 mg per serving

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar monograph & interactions

Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Raw Apple Cider Vinegar 1500 mg by HerbTonics Drug Interactions

Want to check YOUR meds against Raw Apple Cider Vinegar 1500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
162Drugs
89 Moderate 73 Minor

Ingredients driving the most interactions

Apple Cider Vinegar 162

Individual Drug Interactions

The ingredients in Raw Apple Cider Vinegar 1500 mg interact with 162 drugs. Click any drug to see the details.

1 of the 1 ingredient in Raw Apple Cider Vinegar 1500 mg interact with drugs. Each result below shows which ingredient is responsible. Apple Cider Vinegar

Each ingredient & the kinds of drugs it affects

For each ingredient in Raw Apple Cider Vinegar 1500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Raw Apple Cider Vinegar 1500 mg, from the product label.

HerbTonics

See all HerbTonics products
Name
Herbtonics
City
Twinsburg
State
Ohio
ZipCode
44087
Phone Number
1-800-706-2790
Web Address
www.herbtonics.com
Pharmacist Counseling Corner

Raw Apple Cider Vinegar 1500 mg by HerbTonics: Common Questions

Does Raw Apple Cider Vinegar 1500 mg by HerbTonics interact with any medications?
Yes. Based on its ingredients, Raw Apple Cider Vinegar 1500 mg has a known interaction with 162 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Raw Apple Cider Vinegar 1500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does apple cider vinegar actually work for acne or skin problems?
The evidence we hold rates apple cider vinegar as having insufficient reliable evidence for acne and atopic dermatitis (eczema). We can't say whether it works based on the data we hold. If you're interested in using it for skin, talk it over with your doctor first—especially since topical use carries a risk of chemical burns.
Is it safe to take every day for a long time?
In food amounts, yes. But when used as a large supplement dose long-term, safety data is limited, and serious effects like low potassium and bone loss have been reported in rare cases after years of heavy use. Stick to amounts your doctor approves, and don't use large doses or unpasteurized vinegar without checking with them first.
Can I take this if I'm on water pills or a heart medication?
No—not without talking to your doctor first. This product can interact with diuretics (water pills) and digoxin (heart medication) by lowering your potassium, which can cause real problems. Your doctor needs to know you're considering it so they can decide if it's safe for you.
What if I have diabetes and take insulin or diabetes medication?
Talk to your doctor or pharmacist before starting. Apple cider vinegar might lower blood sugar, so combining it with diabetes medication could increase the risk of low blood sugar. Your healthcare provider can advise whether it's safe for your specific situation.
Why should I avoid applying this topically?
There are published reports of chemical burns from topical apple cider vinegar, even from a single application. One case involved a teenager who applied it for 3 days to remove a skin growth and ended up with redness, irritation, and skin erosion. It's not worth the risk.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Raw Apple Cider Vinegar 1500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Raw Apple Cider Vinegar 1500 mg label
Go deeper

The Full Monographs Behind Raw Apple Cider Vinegar 1500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph →
Sources

Sources & How We Checked

Raw Apple Cider Vinegar 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Apple Cider Vinegar 11 references
  1. Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
  2. Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
  3. Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol 2007;7:46. PubMed
  4. Johnston CS, Kim CM, Buller AJ. Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes. Diabetes Care 2004;27:281-2. PubMed
  5. Lhotta, K., Hofle, G., Gasser, R., and Finkenstedt, G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80(2):242-243. PubMed
  6. Bunick CG, Lott JP, Warren CB, et al. Chemical burn from topical apple cider vinegar. J Am Acad Dermatol 2012;67(4):e143-4. PubMed
  7. Feldstein S, Afshar M, Krakowski AC. Chemical Burn from Vinegar Following an Internet-based Protocol for Self-removal of Nevi. J Clin Aesthet Dermatol. 2015 Jun;8(6):50.
  8. Luu LA, Flowers RH, Kellams AL, et al. Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity. Pediatr Dermatol. 2019;36(5):634-639. PubMed
  9. Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC Complement Med Ther 2021;21(1):179. PubMed
  10. Feise NK, Johnston CS. Commercial vinegar tablets do not display the same physiological benefits for managing postprandial glucose concentrations as liquid vinegar. J Nutr Metab 2020;2020:9098739. PubMed
  11. Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh A. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized contro

See these in context on the Apple Cider Vinegar monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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