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Dietary supplement

Red Reishi (Lingzhi) Powder Ingredients & Drug Interactions

by BareOrganics

Red Reishi (Lingzhi) Powder label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Red Reishi (Lingzhi) Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Red Reishi (Lingzhi) Powder is a dietary supplement by BareOrganics with 1 active ingredient. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Red Reishi Mushroom powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Red Reishi (Lingzhi) Powder by BareOrganics

Ask about any prescription or over-the-counter medication and we check it for interactions with Red Reishi (Lingzhi) Powder by BareOrganics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Red Reishi (Lingzhi) Powder by BareOrganics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains one active ingredient: organic Red Reishi Mushroom. Reishi (also called lingzhi) is a mushroom used in traditional medicine, and this product delivers it in powder form with no added inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Reishi Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support longevity and healthy immune system.
  • We looked for evidence on: Aging, Stress, Insomnia, Psychological well-being, immune function, general wellness.
  • The closest evidence on file: Reishi Mushroom is rated "Insufficient Reliable Evidence To Rate" for Insomnia (Natural Medicines).
  • Also on file: Reishi Mushroom is rated "Insufficient Reliable Evidence To Rate" for Stress, Psychological well-being, Aging.

The evidence for reishi mushroom's effectiveness is mixed. For high cholesterol (hyperlipidemia), it's rated possibly ineffective.

For other uses — altitude sickness, Alzheimer's disease, and athletic performance — there isn't enough reliable evidence yet to say whether it works. If you're considering reishi for a specific health concern, talk with your doctor or pharmacist about what the current evidence actually shows for your situation.

The evidence, ingredient by ingredient Reishi Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Reishi mushroom is generally well tolerated in the short term, though long-term safety hasn't been well studied. The most common side effects are dizziness, dry mouth, itching, nausea, rash, and stomach upset.

Some people may experience respiratory allergy to reishi spores, with sore throat and runny nose reported. Rare symptoms include insomnia and headache.

The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know whether it's safe for you or your baby. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Reishi Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Reishi Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 375 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on blood thinners (anticoagulants or antiplatelet drugs), blood pressure medications (antihypertensives), or diabetes drugs. Reishi can interact with all three categories, and dose matters — higher amounts carry greater risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Red Reishi Powder may be worth considering if you're interested in traditional mushroom supplements and don't have concerns with blood pressure, bleeding, or diabetes medications. If you take any blood thinners, blood pressure drugs, or diabetes medications, you'll need to check with your doctor or pharmacist first — the dose you take matters, and individual effects vary.

Pregnant and breastfeeding people should avoid it until they've talked it over with their healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Red Reishi (Lingzhi) Powder, straight from the product label.

Brand BareOrganics
Barcode (UPC) 818423028743
Net contents 4 Ounce(s); 114 Gram(s)
Market status On market
Date entered into DSLD Sep 24, 2021
DSLD ID 254900
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Red Reishi (Lingzhi) Powder by BareOrganics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gram(s)
Maximum serving Sizes:
1 Gram(s)
Servings per container
114
UPC/BARCODE
818423028743
IngredientAmount% DV
organic Red Reishi Mushroom powder1 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Easy peel label

Visit www.bareorganics.com for great recipes and ideas.

Raw

Superfoods to nourish your life.

BPA Free Reusable Container

This container is reusable, BPA free, 100% recyclable, microwave and top shelf dishwasher safe. Let's reduce landfill waste! How do you repurpose your BareOrganics containers? #BarelyUsedBareO

Formula

Raw Organic Red Reishi Powder

Kosher

Mushroom of immortality

Star-K (Kosher)

Keto & Paleo Friendly

Formulation

Red Reishi is known as the "mushroom of immortality" as it is thought to support longevity. They also support a healthy immune system and contain valuable polysaccharides and antioxidants.

Benefits: Longevity and wellness.

Organic

Vegan

Non-GMO Gluten-Free

Healthy immunity

USDA Organic Certified Organic by: CCOF

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested Use: Sprinkle 1 scoop on foods, steep in hot water as a tea or add to your favorite smoothie.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

USDA Organic

Star-K (Kosher)

Precautions

Note: Silica packet included to help maintain freshness. Do not consume.

Warning: If you are pregnant or lactating, consult a healthcare professional before using this product.

Keep out of reach of children.

Do not use this product if tamper-evident seal has been removed or is broken.

Storage

Store in a cool, dry place away from sunlight and moisture.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Red Reishi (Lingzhi) Powder by BareOrganics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Red Reishi (Lingzhi) Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Red Reishi (Lingzhi) Powder by BareOrganics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Gram(s) Dosage formPowder Servings per container114 Amounts shown are per serving.

Organic Red Reishi Mushroom powder

Interacts with
375 drugs
1 Gram(s) per serving

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...

Organic Red Reishi Mushroom powder monograph & interactions
Interaction report

Red Reishi (Lingzhi) Powder by BareOrganics Drug Interactions

Want to check YOUR meds against Red Reishi (Lingzhi) Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
375Drugs
375 Moderate

Ingredients driving the most interactions

organic Red Reishi Mushroom powder 375

Individual Drug Interactions

The ingredients in Red Reishi (Lingzhi) Powder interact with 375 drugs. Click any drug to see the details.

1 of the 1 ingredient in Red Reishi (Lingzhi) Powder interact with drugs. Each result below shows which ingredient is responsible. organic Red Reishi Mushroom powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Red Reishi (Lingzhi) Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Red Reishi Mushroom powder3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
organic Red Reishi Mushroom powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Red Reishi (Lingzhi) Powder, from the product label.

BareOrganics

See all BareOrganics products
Name
BareOrganics
Street Address
9160 E. Bahia Dr.
City
Scottsdale
State
AZ
ZipCode
85260
Web Address
www.bareorganics.com
Pharmacist Counseling Corner

Red Reishi (Lingzhi) Powder by BareOrganics: Common Questions

Does Red Reishi (Lingzhi) Powder by BareOrganics interact with any medications?
Yes. Based on its ingredients, Red Reishi (Lingzhi) Powder has a known interaction with 375 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Red Reishi (Lingzhi) Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Red Reishi if I'm pregnant or breastfeeding?
The safety data advises against it. There isn't enough information to know whether reishi is safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist before taking it if you're pregnant, planning pregnancy, or nursing.
What are the most common side effects?
Most people experience dizziness, dry mouth, itching, nausea, rash, or stomach upset. Some may have respiratory allergy symptoms like sore throat or runny nose. Rare effects include insomnia and headache. Stop and check with your pharmacist if anything bothers you.
Does reishi mushroom actually work for high cholesterol?
No — it's rated possibly ineffective for that. For other uses like Alzheimer's disease, athletic performance, or altitude sickness, there isn't enough reliable evidence yet to say whether it helps.
Is it safe to take long-term?
Short-term use is generally well tolerated, but long-term safety hasn't been well studied. If you're thinking of taking it regularly, check with your doctor or pharmacist about whether it's right for you over time.
Can I take this with my blood pressure medication?
Reishi may lower blood pressure, so combining it with blood pressure drugs could theoretically drop your pressure too low. Check with your doctor or pharmacist before adding this to your routine.
What is Red Reishi mushroom used for?
Reishi, or lingzhi, is a mushroom used in traditional medicine. This product is a powder form, though the evidence for what it actually does in the body is still limited for most claims.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Red Reishi (Lingzhi) Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Red Reishi (Lingzhi) Powder label
Go deeper

The Full Monographs Behind Red Reishi (Lingzhi) Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph →
Sources

Sources & How We Checked

Red Reishi (Lingzhi) Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Reishi Mushroom 17 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
  3. Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
  4. Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
  5. Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
  6. Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
  7. Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
  8. Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
  9. Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
  10. Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
  11. Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
  12. Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
  13. Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
  14. Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
  15. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
  16. Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
  17. Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.

See these in context on the Reishi Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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