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Dietary supplement

Red Reishi Mushroom Ingredients & Drug Interactions

by Brain Forza

Red Reishi Mushroom label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Red Reishi Mushroom against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Red Reishi Mushroom is a dietary supplement by Brain Forza with 1 active ingredient. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Mushroom. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Red Reishi Mushroom by Brain Forza

Ask about any prescription or over-the-counter medication and we check it for interactions with Red Reishi Mushroom by Brain Forza — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Red Reishi Mushroom by Brain Forza

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: reishi mushroom, a fungus traditionally used in herbal medicine. The capsule also holds two inactive ingredients—pullulan and organic sorghum—which are fillers and binders that hold the capsule together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Reishi Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Immune support, stress and sleep.
  • We looked for evidence on: Insomnia, Stress, Psychological well-being, Chronic fatigue syndrome (CFS), Cancer-related fatigue, Anxiety — and 2 related terms.
  • The closest evidence on file: Reishi Mushroom is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS) (Natural Medicines).
  • Also on file: Reishi Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cancer-related fatigue, Insomnia, Stress, Psychological well-being.

The evidence for reishi mushroom is mixed. For high cholesterol (hyperlipidemia), it's rated possibly ineffective—the data doesn't support its use for that purpose.

For other conditions—altitude sickness, Alzheimer disease, and athletic performance—there isn't enough reliable evidence to say whether it works. The facts we hold don't establish effectiveness for any of those uses.

The evidence, ingredient by ingredient Reishi Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Reishi mushroom is generally well tolerated in the short term, but we don't have solid long-term safety data. Common side effects when taken by mouth include dizziness, dry mouth, itching, nausea, rash, and stomach upset.

Some people report sore throat and runny nose, and respiratory allergies to reishi spores can occur. Rarely, insomnia and headache have been reported.

During pregnancy and breastfeeding, there isn't enough safety data, so the safety information advises against use. If you're pregnant or nursing and interested in reishi, talk with your pharmacist or doctor about what's right for your situation.

Side effects, ingredient by ingredient Reishi Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Reishi Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 375 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Red Reishi Mushroom, double-check with your pharmacist if you take any blood thinners (anticoagulant/antiplatelet drugs), blood pressure medications (antihypertensive drugs), or diabetes drugs (antidiabetes drugs). All three have documented Moderate interactions with reishi mushroom.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Reishi mushroom is generally well tolerated short-term, but it does interact with blood thinners, blood pressure pills, and diabetes medications—all Moderate concerns. If you take any of those drugs, check your exact medications with the tool on this page before starting.

Pregnant or nursing? You'll want to talk with your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Red Reishi Mushroom, straight from the product label.

Brand Brain Forza
Barcode (UPC) 857056006032
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 318007
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic, Halal, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Red Reishi Mushroom by Brain Forza, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
857056006032
IngredientAmount% DV
Reishi Mushroom1500 mg--

Other ingredients: Pullulan, organic Sorghum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one capsule three times daily with water or, three capsules once daily with water.

Precautions

Allergens: Manufactured in a facility that processes wheat, gluten, soy, milk, egg, shellfish and tree nut ingredients.

Warning: This product is for adults only. Keep out of reach of children.

Always contact a physician if you are taking medication, have a medical condition, or are pregnant or nursing.

Formulation

Certified Organic

Gluten Free

Certified Organic by CCOF

Longevity & immune support Cardiovascular health support Supports immune system

100% grown in the USA

No rice or oatmeal - our mushrooms are grown on an ancient grain superfood which yields 95%+ mushroom tissue each batch. Brain Forza organic mushrooms are non-GMO, lab-grown, certified organic, full-spectrum and 100% made and grown in the USA. Lab-grown and toxin-free

100% Made and grown in the USA Lab-grown and toxin-free

Full-spectrum Organic

Certified Organic by CCOF

Made in: California

Formula

Halal & Kosher Compliant

Made with organic full-spectrum multi-reishi mushrooms

Brain Forza Mushrooms Brain Forza organic mushrooms are non-GMO, lab-grown, certified organic, full-spectrum and 100% made and grown in the USA.

Our mushrooms are pure, real mushroom tissue - no freeze dried water extract. Ganoderma Mushrooms Use of Ganoderma strains date back as far as 4,000 years, appearing in ancient Chinese and Japanese artwork. Reishi supports overall wellness and longevity.

Halal & Kosher Compliant

Seals/Symbols

CCOF Certified Organic

Made in the USA

General Statements

Organic Mushrooms

About Brain Forza Brain Forza has specialized in making the best organic mushroom and adaptogen powdered products since 2010. Above all, we prioritize quality and science. We are driven by our goal to make the most functional super supplements on the market. Find us and tag us online @brainforza #brainforza

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Red Reishi Mushroom by Brain Forza label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Red Reishi Mushroom label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Red Reishi Mushroom by Brain Forza

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Reishi Mushroom

Interacts with
375 drugs
1500 mg per serving Form: Ganoderma applanatum, Ganoderma applanatum, Ganoderma applanatum, Ganoderma applanatum, Ganoderma lucidum, Ganoderma lucidum, Ganoderma lucidum, Ganoderma lucidum, Ganoderma tsugae, Ganoderma tsugae, Ganoderma tsugae, Ganoderma tsugae

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...

Reishi Mushroom monograph & interactions

Other (inactive) ingredients: Pullulan, Organic Sorghum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Red Reishi Mushroom by Brain Forza Drug Interactions

Want to check YOUR meds against Red Reishi Mushroom?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
375Drugs
375 Moderate

Ingredients driving the most interactions

Reishi Mushroom 375

Individual Drug Interactions

The ingredients in Red Reishi Mushroom interact with 375 drugs. Click any drug to see the details.

1 of the 1 ingredient in Red Reishi Mushroom interact with drugs. Each result below shows which ingredient is responsible. Reishi Mushroom

Each ingredient & the kinds of drugs it affects

For each ingredient in Red Reishi Mushroom with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi Mushroom3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi Mushroom full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Red Reishi Mushroom, from the product label.

Brain Forza

See all Brain Forza products
Name
Brain Forza Labs Inc.
Street Address
200-871 Coronado Center Dr.
City
Henderson
State
NV
ZipCode
89052
Web Address
brainforza.com
Pharmacist Counseling Corner

Red Reishi Mushroom by Brain Forza: Common Questions

Does Red Reishi Mushroom by Brain Forza interact with any medications?
Yes. Based on its ingredients, Red Reishi Mushroom has a known interaction with 375 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Red Reishi Mushroom contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take reishi if I'm pregnant?
There isn't enough safety data to know either way. The safety information advises against use during pregnancy. Talk with your pharmacist or doctor about your personal situation before starting.
Can I take reishi while breastfeeding?
There isn't enough safety data to know either way. The safety information advises against use while breastfeeding. Chat with your pharmacist or doctor before you start.
What are the most common side effects?
The most common ones when taken by mouth are dizziness, dry mouth, itching, nausea, rash, and stomach upset. Some people also report sore throat and runny nose. Respiratory allergies to reishi spores can occur, and rarely, insomnia or headache.
Does reishi mushroom work for high cholesterol?
No—it's rated possibly ineffective for that use. The evidence doesn't support taking it for cholesterol.
Is long-term use of reishi mushroom safe?
Short-term use is generally well tolerated, but we don't have solid data on how safe it is over the long haul. If you're thinking about taking it for months or longer, it's worth discussing with your pharmacist.
What dose of reishi might affect bleeding?
A dose of 1.5 grams daily doesn't seem to affect how your blood clots, but 3 grams daily does appear to increase bleeding risk. This is why we flag reishi as a concern if you take blood thinners.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Red Reishi Mushroom label
Go deeper

The Full Monographs Behind Red Reishi Mushroom’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph →
Sources

Sources & How We Checked

Red Reishi Mushroom's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Reishi Mushroom 17 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
  3. Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
  4. Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
  5. Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
  6. Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
  7. Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
  8. Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
  9. Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
  10. Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
  11. Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
  12. Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
  13. Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
  14. Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
  15. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
  16. Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
  17. Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.

See these in context on the Reishi Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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