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Dietary supplement

Rehmannia 4:1 Extract Powder Ingredients & Drug Interactions

by TerraVita Premium Collection

Rehmannia 4:1 Extract Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Rehmannia 4:1 Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Rehmannia 4:1 Extract Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for kidney and adrenal support, anemia and blood building (traditional), inflammatory conditions.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rehmannia Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Rehmannia 4:1 Extract Powder by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Rehmannia 4:1 Extract Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Rehmannia 4:1 Extract Powder by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: rehmannia extract in powder form, a 4:1 concentration. Rehmannia is a root used in traditional Chinese medicine; this extract form makes it more concentrated than the whole plant material.

There are no other inactive ingredients in this powder.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Rehmannia's overall clinical evidence instead.

Moderate

Some clinical evidence supports Rehmannia for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Chronic kidney disease (CKD) — rated "Possibly Effective" (Natural Medicines).

In our data, rehmannia rates as possibly effective for chronic kidney disease (CKD). For aplastic anemia, atopic disease, osteoporosis, diabetes, and diabetic nephropathy, the evidence is too sparse or mixed to rate — we can't say whether it works for those conditions.

If any of these are reasons you're considering it, that's worth discussing with your doctor, since the science here isn't settled.

The evidence, ingredient by ingredient Rehmannia

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rehmannia is used in traditional medicine but human safety data are limited, and product quality varies from maker to maker. There isn't enough safety information to recommend it during pregnancy or while breastfeeding — if either applies to you, talk with your doctor or pharmacist before taking it.

No adverse effects were reported in the data we hold, but that doesn't mean none can occur; always watch for unusual symptoms when you start something new.

Side effects, ingredient by ingredient Rehmannia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rehmannia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you're on blood pressure medications or diabetes drugs. Moderate-severity interactions are documented for both categories — rehmannia may intensify their effects and cause low blood pressure or low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and some safety-information gaps remain.

Rehmannia may help with chronic kidney disease, though evidence for other uses is uncertain. If you take blood pressure or diabetes medications, you'll need to clear this with your doctor or pharmacist first — the risk of dangerously low blood pressure or blood sugar is real.

Pregnant or breastfeeding? Check with your healthcare provider before starting.

Because human safety data are limited, it's worth a conversation with your own doctor to see if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rehmannia 4:1 Extract Powder, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435212827
Net contents 4 Ounce(s)
Market status On market
Date entered into DSLD Apr 21, 2023
DSLD ID 289820
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rehmannia 4:1 Extract Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
113
UPC/BARCODE
064435212827
IngredientAmount% DV
Rehmannia Extract, Powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Rehmannia 4:1 Extract Powder by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Rehmannia 4:1 Extract Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Rehmannia 4:1 Extract Powder by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container113 Amounts shown are per serving.

Rehmannia Extract, Powder

Interacts with
258 drugs
1000 mg per serving

Rehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human eviden...

Rehmannia Extract, Powder monograph & interactions
Interaction report

Rehmannia 4:1 Extract Powder by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Rehmannia 4:1 Extract Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
258Drugs
258 Moderate

Ingredients driving the most interactions

Rehmannia Extract, Powder 258

Individual Drug Interactions

The ingredients in Rehmannia 4:1 Extract Powder interact with 258 drugs. Click any drug to see the details.

1 of the 1 ingredient in Rehmannia 4:1 Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Rehmannia Extract, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Rehmannia 4:1 Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rehmannia Extract, Powder2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).

Likelihood Possible Evidence D
Rehmannia Extract, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Rehmannia 4:1 Extract Powder, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Rehmannia 4:1 Extract Powder by TerraVita Premium Collection: Common Questions

Does Rehmannia 4:1 Extract Powder by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Rehmannia 4:1 Extract Powder has a known interaction with 258 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rehmannia 4:1 Extract Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant?
There isn't enough safety information to know either way — the data advises against it during pregnancy. Talk with your doctor or pharmacist before taking it; they can help you weigh the risks and benefits for your situation.
What is rehmannia used for?
In traditional medicine, rehmannia is used for several conditions. In our data, it rates as possibly effective for chronic kidney disease, though the evidence for diabetes, osteoporosis, atopic disease, aplastic anemia, and diabetic nephropathy isn't established yet.
Can I take this if I'm breastfeeding?
There isn't enough safety information — the data advises against it while breastfeeding. Check with your doctor or pharmacist before starting to make sure it's appropriate for you.
Will this lower my blood sugar?
Animal research suggests rehmannia may lower blood sugar, which is why there's a documented Moderate risk if you take diabetes medications. If you're diabetic, your doctor or pharmacist needs to review this with you before you start.
What are the side effects?
No adverse effects were reported in the data we have. That said, because human safety information is limited for rehmannia, you should watch for any unusual symptoms when you start taking it and report them to your healthcare provider.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Rehmannia 4:1 Extract Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rehmannia 4:1 Extract Powder label
Go deeper

The Full Monographs Behind Rehmannia 4:1 Extract Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rehmannia

Interacts with 258 drugs

Rehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human evidence for most modern uses is limited, so i...

Read the full Rehmannia monograph →
Sources

Sources & How We Checked

Rehmannia 4:1 Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rehmannia 3 references
  1. Zhang R, Zhou J, Jia Z, et al. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. J Ethnopharmacol 2004;90:39-43. PubMed
  2. Zhang RX, Li MX, Jia ZP. Rehmannia glutinosa: review of botany, chemistry and pharmacology. J Ethnopharmacol 2008;117(2):199-214. PubMed
  3. Chao CH, Hsu JL, Chen MF, et al. Anti-hypertensive effects of Radix Rehmanniae and its active ingredients. Nat Prod Res. 2020;34(11):1547-1552.

See these in context on the Rehmannia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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