Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Reishi Mushroom Buddha Blend Ingredients & Drug Interactions

by Raw Forest Foods

Reishi Mushroom Buddha Blend label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Reishi Mushroom Buddha Blend against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Reishi Mushroom Buddha Blend is a dietary supplement by Raw Forest Foods with 2 active ingredients. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Fruiting Body Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Reishi Mushroom Buddha Blend by Raw Forest Foods

Ask about any prescription or over-the-counter medication and we check it for interactions with Reishi Mushroom Buddha Blend by Raw Forest Foods — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Reishi Mushroom Buddha Blend by Raw Forest Foods

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This blend contains 2 active ingredients: reishi fruiting body extract and reishi. Reishi is a medicinal mushroom traditionally used in herbal medicine.

The product also contains maltodextrin, an inactive filler. We could not review the 'Reishi' ingredient listed separately — we hold no data for it — so we can only speak to the reishi fruiting body extract component.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Reishi Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: mushroom of longevity and well-being.
  • We looked for evidence on: Aging, Stress, Insomnia, Psychological well-being, Cardiovascular disease (CVD), Hyperlipidemia — and 4 related terms.
  • The closest evidence on file: Reishi Mushroom is rated "Possibly Ineffective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Reishi Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Chronic fatigue syndrome (CFS), Cancer-related fatigue, Insomnia, and more.

The evidence for reishi fruiting body extract is limited. For high cholesterol (hyperlipidemia), it's rated possibly ineffective.

For altitude sickness, Alzheimer disease, and athletic performance, there isn't enough reliable evidence yet to say whether it works. Our data doesn't include effectiveness ratings for the second 'Reishi' ingredient.

The evidence, ingredient by ingredient Reishi Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Reishi fruiting body extract is generally well tolerated in the short term, though long-term safety hasn't been well studied. Common side effects include dizziness, dry mouth, itching, nausea, rash, and stomach upset.

Some people report sore throat or runny nose, and respiratory allergy to reishi spores can occur. Rare effects include insomnia and headache.

During pregnancy, the safety data advises against use of reishi fruiting body extract. The same applies to breastfeeding.

We hold no pregnancy or breastfeeding data for the second 'Reishi' ingredient listed, so talk with your doctor or pharmacist for personalized guidance on that component.

Side effects, ingredient by ingredient Reishi Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Reishi Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 375 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this product, double-check if you take blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel) — reishi may raise bleeding risk, especially at higher doses. Also check blood pressure medications (like lisinopril or amlodipine) and diabetes drugs (like metformin or insulin), as reishi can add to their effects.

Use the search tool below with your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Reishi Mushroom Buddha Blend may interest people exploring traditional herbal support, but it's not proven effective for high cholesterol and lacks solid evidence for several other uses. If you take blood thinners, blood pressure medications, or diabetes medications, check with your pharmacist first — the reishi extract can interact with all three.

Avoid it during pregnancy and while breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Reishi Mushroom Buddha Blend, straight from the product label.

Brand Raw Forest Foods
Barcode (UPC) 850004627419
Net contents 2.47 Ounce(s); 70 Gram(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 337184
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Reishi Mushroom Buddha Blend by Raw Forest Foods, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
35
UPC/BARCODE
850004627419
IngredientAmount% DV
Reishi Fruiting Body Extract1000 mg--
Reishi1000 mg--

Other ingredients: Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

The mushroom of longevity Ready to use

Founded in 2010, RAW Forest Foods is your home for tonic and adaptogenic herbs and supplements. We proudly - artfully and professionally - craft products meeting our own discerningly high standards, which we share with you. Using hand-selected, premier ingredients, and formulated by our master herbalist, we invite you to Discover the Infinite Power Within.

No fillers, drying agents, and never irradiated. This product is GMO free.

No fillers, drying agents, and never irradiated.

Vegan

Formula

Cracked cell wall raw reishi spores fortified with reishi fruiting body standardized to 30% polysaccharides

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults use 2 grams (roughly 1/2 teaspoon) per serving, preferably on an empty stomach, taken 1-2 times per day. As with all dietary supplements, please consult a qualified healthcare practitioner prior to use. This expertly prepared blend of powders is ready to use. Simply add the desired amount to several ounces of warm water, stir, and enjoy.

Precautions

Warning: Not for use by those under the age of 18, who are pregnant or nursing, or who are allergic or adverse to any of the ingredients contained within. Keep out of the reach of children.

Warning: Not for use by those under the age of 18, who are pregnant or nursing, or who are allergic or adverse to any of the ingredients contained within.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool dry place.

Seals/Symbols

Vegan

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Reishi Mushroom Buddha Blend by Raw Forest Foods label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Reishi Mushroom Buddha Blend label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Reishi Mushroom Buddha Blend by Raw Forest Foods

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container35 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Reishi Fruiting Body Extract

Interacts with
375 drugs
1000 mg per serving Form: Ganoderma lucidum Fruiting Body Extract, Polysaccharides

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...

Reishi Fruiting Body Extract monograph & interactions

Reishi

Interacts with
375 drugs
1000 mg per serving Form: Ganoderma lucidum, Ganoderma lucidum

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...

Reishi monograph & interactions

Other (inactive) ingredients: Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Reishi Mushroom Buddha Blend by Raw Forest Foods Drug Interactions

Want to check YOUR meds against Reishi Mushroom Buddha Blend?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
375Drugs
375 Moderate

Ingredients driving the most interactions

Reishi Fruiting Body Extract 375

Individual Drug Interactions

The ingredients in Reishi Mushroom Buddha Blend interact with 375 drugs. Click any drug to see the details.

1 of the 2 ingredients in Reishi Mushroom Buddha Blend interact with drugs. Each result below shows which ingredient is responsible. Reishi Fruiting Body Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Reishi Mushroom Buddha Blend with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi Fruiting Body Extract3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi Fruiting Body Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Reishi Mushroom Buddha Blend, from the product label.

Raw Forest Foods

See all Raw Forest Foods products
Name
RAW Forest Foods
Street Address
PO Box 102
City
Burlington
State
VT
ZipCode
05402
Phone Number
802-349-1347
Web Address
www.rawforestfoods.com
Pharmacist Counseling Corner

Reishi Mushroom Buddha Blend by Raw Forest Foods: Common Questions

Does Reishi Mushroom Buddha Blend by Raw Forest Foods interact with any medications?
Yes. Based on its ingredients, Reishi Mushroom Buddha Blend has a known interaction with 375 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Reishi Mushroom Buddha Blend contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is reishi, and what's it supposed to do?
Reishi is a medicinal mushroom used traditionally in herbal medicine. This product contains reishi fruiting body extract. The evidence doesn't establish that it works for high cholesterol, and there isn't enough reliable data yet to say whether it helps with altitude sickness, Alzheimer disease, or athletic performance.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against use of the reishi fruiting body extract during pregnancy and while breastfeeding. There isn't enough data to know either way for the other ingredient listed. Talk with your doctor or pharmacist about what's right for you.
What side effects might I notice?
Most people tolerate it without trouble, but dizziness, dry mouth, itching, nausea, rash, and stomach upset are the most common. Some report sore throat or runny nose, and rarely, insomnia or headache. Respiratory allergy to reishi spores is possible.
Is this safe to use long-term?
It's generally well tolerated in the short term, but long-term safety hasn't been well studied, so we don't have good data on how safe it is over months or years. Talk with your pharmacist if you're planning to use it regularly.
Why does the label list 'Reishi' twice — as 'Reishi Fruiting Body Extract' and just 'Reishi'?
The product does list two ingredients that both relate to reishi. We hold interaction and safety data only for the reishi fruiting body extract; we have no data on file for the ingredient listed simply as 'Reishi.' Your pharmacist can help clarify what that second ingredient is.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Reishi Mushroom Buddha Blend is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Reishi Mushroom Buddha Blend label
Go deeper

The Full Monographs Behind Reishi Mushroom Buddha Blend’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph →
Sources

Sources & How We Checked

Reishi Mushroom Buddha Blend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Reishi Mushroom 17 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
  3. Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
  4. Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
  5. Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
  6. Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
  7. Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
  8. Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
  9. Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
  10. Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
  11. Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
  12. Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
  13. Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
  14. Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
  15. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
  16. Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
  17. Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.

See these in context on the Reishi Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team