Interactions on record — worth a quick check against your medications. Based on 9 of 11 ingredients. Check your meds →
Dietary supplement

Relaxed Mind Ingredients & Drug Interactions

by Yogi

Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Relaxed Mind is a dietary supplement by Yogi with 11 active ingredients. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 1,427 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Sage, organic Gotu Kola, Stevia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Relaxed Mind by Yogi

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 11 active ingredients.
  • “Proprietary Blend of Herbs” is a proprietary blend — the label gives one combined amount (1,784 mg) without saying how much of each component you get.

Yogi Relaxed Mind is a tea blend with 11 active herbal ingredients: a proprietary blend of herbs plus stevia, nettle, skullcap, lavender, sage, gotu kola, chrysanthemum, lemon myrtle, blackberry, shankhpushpi, and helichrysum. Several of these — nettle, skullcap, lavender, sage, and gotu kola — have traditionally been used for calming or stress-related purposes.

The formula also contains inactive flavoring ingredients (boysenberry and lavender flavors) that are not medicinal components.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: relaxation and stress relief.
  • We looked for evidence on: Anxiety, Generalized anxiety disorder (GAD), Insomnia, Nervous tension, Sleep quality, Calming.
  • The closest evidence on file: Gotu Kola is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD) (Natural Medicines).
  • Also on file: Lavender is rated "Insufficient Reliable Evidence To Rate" for Pre-procedural anxiety, Insomnia, Perioperative anxiety.
  • Also on file: Skullcap is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Insomnia.

The evidence for this product's effectiveness is mixed and limited. Sage is possibly effective for menopausal symptoms, high cholesterol, and cognitive function; lavender is possibly effective for period pain; and nettle is possibly effective for blood sugar control in diabetes.

However, the other key ingredients — stevia, skullcap, gotu kola, chrysanthemum, lemon myrtle, blackberry, shankhpushpi, and helichrysum — lack sufficient reliable evidence to rate them for relaxation or stress relief. Most of the traditional uses claimed for products like this have not been well studied in humans.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 9 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these herbs are generally well tolerated in typical short-term use, though side effects do occur. Stevia may cause headache, dizziness, numbness, nausea, abdominal bloating, or muscle pain (usually mild and temporary).

Nettle commonly causes constipation or diarrhea. Skullcap can cause sedation, cognitive impairment, and digestive disturbances.

Lavender may cause headache, nausea, constipation, or diarrhea. Sage can cause nausea, vomiting, abdominal pain, diarrhea, or dizziness.

Gotu kola may cause stomach upset and nausea. Serious adverse effects are rare across all these herbs, but case reports exist for liver injury (gotu kola) and allergic reactions (stevia, lavender, chrysanthemum).

Pregnancy safety is a significant concern: nettle, skullcap, sage, and gotu kola all lack sufficient safety data or carry warnings against use in pregnancy — talk with your doctor before using this product if you are pregnant or breastfeeding.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 9 matched ingredients can interact with medications — Sage, Stinging Nettle, Stevia, Gotu Kola, Lavender, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications; lithium.
  • For scale: 1,428 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you use any CNS depressants (Moderate severity) — that includes sedatives, sleep aids, anti-anxiety medications, and opioid pain relievers. Also discuss it if you take blood sugar medications, blood pressure drugs, lithium, blood thinners like warfarin, liver-toxic medications, hormone therapies (including birth control and hormone replacement), or any drugs that are metabolized by your liver's CYP450 enzymes (CYP2D6, CYP2C19, CYP2C9, CYP3A4) or the P-glycoprotein transporter — your pharmacist can tell you if yours fit these categories.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Yogi Relaxed Mind is aimed at people seeking herbal support for relaxation, but the scientific evidence for its effectiveness is sparse. Because it contains multiple herbs that interact with CNS depressants, blood sugar medications, blood thinners, and other common drugs, and because pregnancy safety is not well established, this is one to clear with your own doctor or pharmacist before you start — especially if you take any prescription medications, manage diabetes, use blood pressure or mood medications, or are pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Relaxed Mind, straight from the product label.

Brand Yogi
Barcode (UPC) 076950450226
Net contents 16 Tea Bag(s); 1.12 Oz(s); 32 Gram(s)
Market status On market
Date entered into DSLD May 24, 2017
DSLD ID 73196
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Relaxed Mind by Yogi, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tea Bag(s)
Maximum serving Sizes:
2 Tea Bag(s)
UPC/BARCODE
076950450226
IngredientAmount% DV
Proprietary Blend of Herbs1784 mg--
Stevia0 NP--
organic Nettle0 NP--
organic Skullcap0 NP--
organic Lavender0 NP--
organic Sage0 NP--
organic Gotu Kola0 NP--
Chrysanthemum0 NP--
organic Lemon Myrtle0 NP--
organic Blackberry0 NP--
organic Shankhpushpi0 NP--
organic Helichrysum0 NP--

Other ingredients: natural Boysenberry flavor, organic Lavender flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Quality Assurance International Certified organic

OU

V vegan

Certified circle B corporation

Non GMO Project Verified nongmoproject.org

Formula

Circle U

Made with organic sage leaf

Yogi’s blissful blend begins with helichrysum, used in western herbalism for centuries and believed by herbalists to uplift the subconscious. Then we add shankpushpi, used in Auyrveda to support cognition. We finish this unique formula with aromatic lavender and organic sage, herbs traditionally used to balance your mood and nurture creativity.

Formulation

V vegan

Quality Assurance International Certified organic

Non GMO

Caffeine free

Certified organic by QAI, Inc.

General Statements

Recyclable Compostable tea bags

100% Recycled paper board

To help protect our forests and reduce landfill burden, Yogi tea cartons use 100% recycled paperboard, 55% post consumer waste, and are printed with environmentally-friendly vegetable-based inks.

Love our tea as much as we do or we’ll gladly refund your money. Inspire us and yourself at www.yogiproducts.com

Recyclable Non-irradiated Oxygen-bleached tea bags Please recycle this box.

Yoga for clarity of mind Sit cross-legged or in a chair with spine straight and feet flat. Close your eyes and block left nostril with left hand. Take deep, slow breaths through the right nostril. Continue 1 to 3 minutes with focus on your breath. A clear mind opens the window to happiness. Before doing this exercise or participating in any exercise program, consult your physician.

Our story began in 1969 when Yogi Bhajan, an inspirational teacher of holistic living, started teaching yoga in the west. He shared with his students his wisdom and knowledge of healthy living and the beneficial properties of herbs, all while serving a comforting and aromatic spiced tea they affectionately named “Yogi Tea”.

Promotes tranquility

Center yourself with Relaxed Mind Soothe your mind and refresh your spirit with our fragrant Relaxed Mind.

Relax and enjoy this soothing and sophisticated one-of-a-kind blend that may bring you to a state of pure relaxation and tranquility.

Brand IP Statement(s)

2014 East West Tea Company, LLC

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Get the most out of every cup Bring water just to boiling and steep 5 to 10 minutes. For a stronger tea, use 2 tea bags.

Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant.

See for yourself

Relaxed Mind by Yogi label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Relaxed Mind by Yogi

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tea Bag(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend of Herbs

1784 mg per serving

Other (inactive) ingredients: Natural Boysenberry flavor, Organic Lavender flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Relaxed Mind by Yogi Drug Interactions

Want to check YOUR meds against Relaxed Mind?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,427Drugs
1,427 Moderate

Ingredients driving the most interactions

organic Sage 1,296
Stevia 259

Each ingredient & the kinds of drugs it affects

For each ingredient in Relaxed Mind with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Sage14 drug types · 1,296 drugs

Anticholinergic Drugs

Theoretically, sage might decrease the clinical effects of anticholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.

Likelihood Possible Evidence D
Anticonvulsants

Theoretically, sage might interfere with the clinical effects of anticonvulsant drugs.
Some species of sage can cause convulsions when consumed in large quantities.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking sage with antidiabetes drugs might increase the risk of hypoglycemia.
In patients with polycystic ovary syndrome (PCOS) or inadequately controlled type 2 diabetes, common sage (Salvia officinalis) has demonstrated hypoglycemic activity. However, other clinical research in patients with inadequately controlled type 2 diabetes shows that common sage extract does not lower fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Animal research suggests that common sage (Salvia officinalis) can cause prolonged blood pressure reduction. However, clinical research suggests that Spanish sage (Salvia lavandulaefolia) can increase blood pressure in some people with hypertension. Until more is known, use with caution.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking sage might increase the sedative and adverse effects of benzodiazepines.
In vitro evidence suggests that certain components of common sage (Salvia officinalis) can bind to benzodiazepine receptors. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, sage might have additive effects when used with cholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Some constituents of sage have CNS depressant activity.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C19.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C9.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2D6. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Animal research suggests that drinking common sage (Salvia officinalis) tea increases the expression of CYP2E1. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP3A4. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, sage might interfere with hormone therapy.
In vitro evidence suggests that geraniol, a constituent of Spanish sage (Salvia lavandulaefolia), exerts estrogenic activity. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, sage might increase levels of drugs transported by P-glycoprotein.
In vitro research suggests that common sage (Salvia officinalis) can inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.

Likelihood Possible Evidence D

organic Gotu Kola2 drug types · 579 drugs

Cns Depressants

Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.

Likelihood Possible Evidence D

Stevia3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D

organic Skullcap1 drug type · 248 drugs

Cns Depressants

Theoretically, skullcap can have additive effects when used with other CNS depressants.
Animal and clinical research suggests that skullcap can cause sedation and cognitive impairment.

Likelihood Possible Evidence D

organic Lavender1 drug type · 248 drugs

Cns Depressants

Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Laboratory research suggests that lavender has sedative effects. However, clinical studies in patients taking oral lavender oil (Silexan) 160 mg for 10 weeks or taking lavender flower powder 1 gram daily for 2 months have not reported side effects of drowsiness, sedation, or sleepiness. There is still some concern that higher doses or different preparations of lavender might have additive effects with CNS depressant medications.

Likelihood Unlikely Evidence D

organic Nettle4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Relaxed Mind, from the product label.

Yogi

See all Yogi products
Name
YOGI A product of East West Tea Company, LLC
Street Address
950 International Way
City
Springfield
State
OR
ZipCode
97477
Web Address
www.yogiproducts.com
Pharmacist Counseling Corner

Relaxed Mind by Yogi: Common Questions

Does Relaxed Mind by Yogi interact with any medications?
Yes. Based on its ingredients, Relaxed Mind has a known interaction with 1,427 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Relaxed Mind contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Safety data are limited or concerning for most of the herbs in this blend. Nettle, skullcap, and sage carry warnings against pregnancy use; gotu kola's pregnancy safety is unclear; and several others lack enough information to know either way. Talk with your doctor or pharmacist before using this product if you are pregnant, breastfeeding, or planning to become pregnant — they can weigh the risks and benefits for your situation.
What is this tea supposed to do?
Yogi Relaxed Mind is marketed as a blend to support relaxation and calm. However, the scientific evidence that these specific herbs work for stress or anxiety is weak or absent. Some ingredients like sage and lavender have been studied for other uses (menopausal symptoms, period pain, cholesterol), but not much human research backs their use for relaxation.
Will this make me sleepy?
Skullcap, lavender, sage, and gotu kola all have sedative properties and can cause drowsiness, especially at higher doses. If you're sensitive to these effects or need to stay alert, start cautiously and avoid combining this tea with other sedating medications or alcohol without first talking to your doctor.
What side effects might I experience?
Most people tolerate these herbs well, but common mild effects include headache, nausea, stomach upset, diarrhea, or constipation. Some people report dizziness, numbness, or muscle aching. Serious side effects like allergic reactions or liver injury are rare but have been reported. Stop use and contact your healthcare provider if you develop unusual symptoms or yellowing of the skin or eyes.
Is stevia in this product safe?
Purified stevia used as a sweetener in food amounts is generally considered safe. However, whole-leaf stevia and high-dose supplements are less well studied. The amount in this tea should be modest, but if you have concerns — especially if you take lithium or blood sugar medications — check with your pharmacist first.
What exactly is in the 'proprietary blend'?
The product contains a proprietary blend of herbs whose exact amounts are not disclosed; you'll see only the total ingredient list. This means you cannot know the individual strength of each herb, making it harder to predict effects or interactions. If you need precise dosing information, contact the manufacturer directly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Relaxed Mind label
Go deeper

The Full Monographs Behind Relaxed Mind’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Herb & supplement monograph

Stinging Nettle

Interacts with 164 drugs

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...

Read the full Stinging Nettle monograph →
Herb & supplement monograph

Skullcap

Interacts with 248 drugs

American skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited. It is generally considered relatively safe for short-term us...

Read the full Skullcap monograph →
Herb & supplement monograph

Lavender

Interacts with 248 drugs

Lavender is a fragrant herb most popular for promoting relaxation, easing anxiety, and supporting sleep, with some encouraging evidence for a standardized oral lavender oil product for anxie...

Read the full Lavender monograph →
Herb & supplement monograph

Sage

Interacts with 1,296 drugs

Sage is a common kitchen herb that is generally safe in food amounts and is traditionally used for sore throats, digestion, sweating, and memory. Some early research is encouraging for sore...

Read the full Sage monograph →
Herb & supplement monograph

Gotu Kola

Interacts with 579 drugs

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...

Read the full Gotu Kola monograph →
Herb & supplement monograph

Chrysanthemum

Chrysanthemum flowers are most often used as a soothing tea in traditional Chinese medicine and as a folk remedy for eye irritation, colds, and minor inflammation. Solid human evidence for t...

Read the full Chrysanthemum monograph →
Herb & supplement monograph

Blackberry

Blackberry is a common edible berry that is safe and nutritious as a food, rich in vitamin C, fiber, and antioxidant plant compounds. The leaves and root have a long history of traditional u...

Read the full Blackberry monograph →
Herb & supplement monograph

Sandy Everlasting

Sandy Everlasting (Helichrysum arenarium) is a yellow-flowered plant used in traditional European herbal medicine, mainly for digestive and liver-related complaints. Human evidence for its b...

Read the full Sandy Everlasting monograph →
Sources

Sources & How We Checked

Relaxed Mind's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 130 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Stinging Nettle 23 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  5. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
  8. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
  9. Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
  10. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8. PubMed
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Skullcap 3 references
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Lavender 20 references
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Sage 27 references
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Gotu Kola 18 references
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Chrysanthemum 25 references
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Blackberry 1 reference
  1. Antioxidants: In Depth — NIH NCCIH Source

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Sandy Everlasting 3 references
  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source
  3. About Herbs, Botanicals & Other Products — Memorial Sloan Kettering Cancer Center Source

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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