Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Reversitol V2 Ingredients & Drug Interactions

by iForce Nutrition

Reversitol V2 label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Reversitol V2 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Reversitol V2 is a dietary supplement by iForce Nutrition with 5 active ingredients. Its ingredients are commonly taken for boosting testosterone, reducing estrogen (aromatase inhibition), athletic and bodybuilding performance.Based on those ingredients, 910 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Trans Resveratrol, Indole 3 Carbinol, Long Jack 100:1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Reversitol V2 by iForce Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Reversitol V2 by iForce Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Reversitol V2 by iForce Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “S.E.R.M. Matrix Proprietary Blend” is a proprietary blend — the label gives one combined amount (200 mg) without saying how much of each component you get.
  • “Estrogen Modulation Matrix (EMM) Proprietary Blend” is a proprietary blend — the label gives one combined amount (160 mg) without saying how much of each component you get.

Reversitol V2 contains 5 active ingredients. The main one is trans resveratrol, a polyphenol from plants.

You'll also find indole-3-carbinol (a compound from cruciferous vegetables like broccoli), 7-methoxyflavone (a flavonoid), ellagic acid (a polyphenol from berries and pomegranate), and long jack (an herbal extract also called eurycoma longifolia). The product also includes a proprietary S.E.R.M.

Matrix blend and an Estrogen Modulation Matrix blend — their exact component amounts aren't disclosed, but the individual ingredients in them are listed separately. Rice flour and magnesium stearate are included as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: optimize hormone production and testosterone.
  • We looked for evidence on: Age-related testosterone deficiency, Athletic performance, Erectile dysfunction (ED), Male Infertility, Muscle strength, Sexual desire — and 3 related terms.
  • The strongest evidence on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire (Natural Medicines).
  • Also on file: Eurycoma Longifolia is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Eurycoma Longifolia is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Muscle strength, Age-related testosterone deficiency, Male Infertility.

The evidence for resveratrol shows it's possibly effective for obesity and allergic rhinitis (hay fever), but possibly ineffective for cardiovascular disease and high cholesterol. For indole-3-carbinol, breast cancer, colorectal cancer, cervical dysplasia, liver disease, and fibromyalgia — the evidence isn't established enough to rate.

Ellagic acid shows insufficient evidence to rate for bladder cancer, cognitive function, diabetes, melasma, and polycystic ovary syndrome. Long jack is possibly effective for sexual desire but possibly ineffective for athletic performance; evidence is insufficient to rate it for back pain, osteoporosis, and diabetes.

The evidence for 7-methoxyflavone isn't established in the data we hold.

The evidence, ingredient by ingredient 7-methoxyflavone Ellagic Acid Resveratrol Indole-3-carbinol Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Resveratrol is generally well tolerated at typical supplement doses, but higher doses may cause digestive upset — diarrhea, gastrointestinal discomfort, and loose stools are the most common oral side effects. A small number of people taking higher doses have reported headache, fatigue, and memory loss, though a cause-and-effect link hasn't been proven.

A rare rash has also been reported and resolved after stopping. The safety data advises against concentrated resveratrol supplements during pregnancy and while breastfeeding.

Indole-3-carbinol is well tolerated orally but can cause diarrhea, nausea, rash, and at higher doses unsteadiness and tremor — these resolved when doses were lowered. The safety data advises against it during pregnancy and while breastfeeding.

Ellagic acid is generally safe in foods, but concentrated supplements are not well studied; a small number of people in one trial had nausea and diarrhea. The safety data advises against concentrated supplements during pregnancy and breastfeeding.

Long Jack is generally tolerated short-term in studies, though long-term safety is uncertain; it may increase testosterone and related side effects like acne and liver stress. The safety data advises against it during pregnancy and while breastfeeding.

We hold no safety data on file for 7-methoxyflavone, but the label advises against it due to unknown safety and possible hormonal effects during pregnancy and breastfeeding.

Side effects, ingredient by ingredient 7-methoxyflavone Ellagic Acid Resveratrol Indole-3-carbinol Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Resveratrol, Indole-3-carbinol, Ellagic Acid, Eurycoma Longifolia, 7-methoxyflavone.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 911 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact medications before starting, especially if you take blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel) — resveratrol and indole-3-carbinol may increase bleeding risk. If you take diabetes medications, ellagic acid might lower your blood sugar too much.

Heart or blood pressure drugs metabolized by your liver (including propranolol) may be affected by multiple ingredients here. Testosterone therapy or aromatase inhibitors (breast cancer drugs) could interact with the 7-methoxyflavone and long jack.

Any drug metabolized by CYP1A2, CYP2C19, CYP2A6, or CYP3A4 liver pathways deserves a quick check — the ingredients here may theoretically affect levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is marketed for hormonal balance and antioxidant support, but evidence is mixed — resveratrol shows promise for obesity and hay fever, while most other claims lack solid proof. If you take blood thinners, diabetes medications, heart or blood pressure drugs, testosterone therapy, or breast cancer medications, you need to check with your pharmacist first.

Pregnant or breastfeeding women should avoid all of these ingredients. Talk to your pharmacist or doctor before starting, especially if you're on any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Reversitol V2, straight from the product label.

Brand iForce Nutrition
Net contents 84 Capsule(s)
Market status On market
Date entered into DSLD Nov 25, 2011
DSLD ID 2429
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Reversitol V2 by iForce Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
84
IngredientAmount% DV
Trans Resveratrol0 NP--
Indole 3 Carbinol0 NP--
S.E.R.M. Matrix Proprietary Blend200 mg--
7-Methoxy-2-phenyl-chromen-4-one0 NP--
Ellagic Acid 95%0 NP--
Estrogen Modulation Matrix (EMM) Proprietary Blend160 mg--
Long Jack 100:10 NP--

Other ingredients: Rice Flour, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 3 capsules per day. One capsule upon waking and 2 capsules just before bed. Use this product for 4-8 weeks followed by an off period of 4 weeks before resuming use.

Precautions

KEEP OUT OF REACH OF CHILDREN.

Do not take this product if you are subject to “prohibited substance” testing by a sports organizations or other administrative body.

Do not use if safety seal is broken or missing.

Warnings: This product is only intended to be consumed by healthy adult males, 21 years of age or older. NOT intended for women. Consult with your physician before using this or any other dietary supplement product. Do not use this product without consulting your physician if you are using any prescription or over the counter medication or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAO-B inhibitor or any other medication. Immediately discontinue use and consult your physician if you experience any adverse reaction to this product. Do not exceed recommended serving.

FDA Disclaimer Statement

† These statements have not been evaluated by the Food and Drug administration. This product is not intended to treat, diagnose, cure or prevent any disease.

General Statements

Athletes across the world trust Reversitol V2 to help them optimize hormone production, which is important for optimal performance, muscle mass, and strength. Supplementing your diet with Reversitol V2 may promote optimization of key anabolic and anti-catabolic hormones through key ingredients, while helping your body balance hormones that can hinder your gains and reduce your body’s anabolic potential.

HORMONAL REGULATOR

Key Ingredients in Reversitol V2 have been shown to: • Help Stimulate Natural Testosterone Production † • Act as s Natural S.E.R.M. † • Act as a Natural Myotropic Amplifier †

NOW 40% MORE FREE!

STATE OF THE ART HORMONAL OPTIMIZER

Visit www.iFORCEnutrition.com for details.

Brand IP Statement(s)

FOR PEAK PERFORMANCE STACK THESE iFORCE PRODUCTS: Maximize(TM) - Preworkout Powerhouse Protodrol V2(TM) - Anabolic Maximizer Hemavol(TM) - Plasma Volumizer

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Reversitol V2 by iForce Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Reversitol V2 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Reversitol V2 by iForce Nutrition

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container84 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

S.E.R.M. Matrix Proprietary Blend

200 mg per serving

Estrogen Modulation Matrix (EMM) Proprietary Blend

160 mg per serving

Other (inactive) ingredients: Rice Flour, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Reversitol V2 by iForce Nutrition Drug Interactions

Want to check YOUR meds against Reversitol V2?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
910Drugs
909 Moderate 1 Minor

Ingredients driving the most interactions

Trans Resveratrol 822
Indole 3 Carbinol 294
Long Jack 100:1 248
Ellagic Acid 95% 86
7-Methoxy-2-phenyl-chromen-4-one 12

Individual Drug Interactions

The ingredients in Reversitol V2 interact with 910 drugs. Click any drug to see the details.

5 of the 5 ingredients in Reversitol V2 interact with drugs. Each result below shows which ingredient is responsible. Trans Resveratrol Indole 3 Carbinol Long Jack 100:1 Ellagic Acid 95% 7-Methoxy-2-phenyl-chromen-4-one

Each ingredient & the kinds of drugs it affects

For each ingredient in Reversitol V2 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Trans Resveratrol5 drug types · 822 drugs

Anticoagulant/Antiplatelet Drugs

Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.

Likelihood Possible Evidence D
Trans Resveratrol full monograph & interactions

Indole 3 Carbinol3 drug types · 294 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, indole-3-carbinol might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro research shows that indole-3-carbinol inhibits platelet aggregation.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, indole-3-carbinol might increase the metabolism of CYP1A2 substrates and lower serum concentrations.
Animal research shows that indole-3-carbinol induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Estrogens

Indole-3-carbinol might interfere with the effects of estrogen therapy.
Preliminary clinical and in vitro evidence shows that indole-3-carbinol has antiestrogenic activity.

Likelihood Possible Evidence D
Indole 3 Carbinol full monograph & interactions

Long Jack 100:15 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
Long Jack 100:1 full monograph & interactions

Ellagic Acid 95%1 drug type · 86 drugs

Antidiabetes Drugs

Some clinical research shows that ellagic acid reduces fasting and postprandial glucose levels in patients with type 2 diabetes who are on stable doses of hypoglycemic agents such as metformin. Theoretically, taking ellagic acid with antidiabetes drugs might increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Ellagic Acid 95% full monograph & interactions

7-Methoxy-2-phenyl-chromen-4-one2 drug types · 12 drugs

Aromatase Inhibitors

In vitro evidence shows that 7-methoxyflavone inhibits aromatase. Theoretically, 7-methoxyflavone might have an additive effects when used with other aromatase inhibitors, potentially increasing the therapeutic effects and adverse effects associated with these drugs. Some aromatase inhibitors include anastrozole (Arimidex), exemestane (Aromasin), and letrozole (Femara).

Likelihood Possible Evidence D
Testosterone

In vitro evidence shows that 7-methoxyflavone inhbits aromatase. Inhibiting aromatase reduces the conversion of testosterone and other androgens to estrogens. Theoretically, use of 7-methoxyflavone with testosterone might increase the effects and side effects of testosterone therapy.

Likelihood Possible Evidence D
7-Methoxy-2-phenyl-chromen-4-one full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Reversitol V2, from the product label.

iForce Nutrition

See all iForce Nutrition products
Name
Tribravus Enterprises, LLC
City
Escondido
State
CA
ZipCode
92029
Phone Number
1-877-743-6460
Web Address
www.iforcenutrition.com
Pharmacist Counseling Corner

Reversitol V2 by iForce Nutrition: Common Questions

Does Reversitol V2 by iForce Nutrition interact with any medications?
Yes. Based on its ingredients, Reversitol V2 has a known interaction with 910 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Reversitol V2 contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Reversitol V2 if I'm pregnant or breastfeeding?
The safety data advises against all of these ingredients during pregnancy and breastfeeding. There isn't enough information to know if they're safe at supplement doses for you or your baby, so talk with your doctor or pharmacist for personalized advice.
What are the most common side effects of this product?
Digestive upset is the most common issue — resveratrol and indole-3-carbinol can both cause diarrhea and gastrointestinal discomfort. At higher doses, indole-3-carbinol has been linked to unsteadiness and tremor, though these went away when the dose was reduced. A small number of people have reported nausea, rash, headache, and fatigue.
Does this product actually work for weight loss?
Resveratrol, the main ingredient here, is possibly effective for obesity based on the evidence we have. That means some research supports it, but the proof isn't rock solid yet. It's not a replacement for diet and exercise.
Can I take this with my blood pressure medication?
Long jack may reduce the effectiveness of propranolol specifically — it lowered blood levels in one small study. Other ingredients may theoretically affect how your liver breaks down blood pressure drugs. Check with your pharmacist about your exact medication before starting.
What is indole-3-carbinol?
It's a natural compound found in cruciferous vegetables like broccoli, cabbage, and Brussels sprouts. In this supplement it's concentrated into a higher dose than you'd get from food alone.
Can I take this if I'm on hormone therapy or birth control?
Indole-3-carbinol has antiestrogenic activity and might interfere with estrogen therapy or birth control effectiveness. Talk to your doctor or pharmacist before adding this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Reversitol V2 label
Go deeper

The Full Monographs Behind Reversitol V2’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

7-methoxyflavone

Interacts with 12 drugs

7-Methoxyflavone is a lab-made or plant-derived flavonoid marketed mainly in testosterone-boosting and bodybuilding supplements based on the idea that it blocks the aromatase enzyme. However...

Read the full 7-methoxyflavone monograph → Herb & supplement monograph

Ellagic Acid

Interacts with 86 drugs

Ellagic acid is a natural plant compound (a polyphenol) found in foods like pomegranates, raspberries, strawberries, and walnuts. It is studied mostly in laboratory and animal research for a...

Read the full Ellagic Acid monograph → Herb & supplement monograph

Resveratrol

Interacts with 822 drugs

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While lab and animal studies are promising, s...

Read the full Resveratrol monograph → Herb & supplement monograph

Indole-3-carbinol

Interacts with 294 drugs

Indole-3-carbinol (I3C) is a compound formed when you eat cruciferous vegetables like broccoli and cabbage, and it is sold as a supplement mainly for hormone-related and cell-protective effe...

Read the full Indole-3-carbinol monograph → Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph →
Sources

Sources & How We Checked

Reversitol V2's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 47 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Resveratrol 24 references
  1. Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
  2. Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
  3. Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
  4. Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
  5. Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
  6. Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
  7. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
  8. Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
  9. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
  10. Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
  11. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
  12. Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
  13. Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
  14. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
  15. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
  16. Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
  17. Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
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7-methoxyflavone 1 reference
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Ellagic Acid 9 references
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Eurycoma Longifolia 4 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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