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Dietary supplement

Tribulus 2400 Ingredients & Drug Interactions

by iForce Nutrition

Tribulus 2400 label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tribulus 2400 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tribulus 2400 is a dietary supplement by iForce Nutrition with 1 active ingredient. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Proprietary Tribulus 2400 Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Tribulus 2400 by iForce Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Tribulus 2400 by iForce Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tribulus 2400 by iForce Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Tribulus 2400 Blend” is a proprietary blend — the label gives one combined amount (800 mg) without saying how much of each component you get.

Tribulus 2400 contains one active ingredient: a Bulgarian Tribulus terrestris extract in a proprietary blend at 2400 mg per serving. The capsules also include rice flour and magnesium stearate as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Increased testosterone, sex drive, muscle strength.
  • We looked for evidence on: Athletic performance, Erectile dysfunction (ED), Exercise-induced muscle damage, Male infertility, Premature ejaculation, Sexual dysfunction — and 4 related terms.
  • The strongest evidence on file: Tribulus is rated "Possibly Effective" for Sexual dysfunction (Natural Medicines).
  • Also on file: Tribulus is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Premature ejaculation, Male infertility, Exercise-induced muscle damage.

Tribulus terrestris is rated possibly effective for sexual dysfunction. The evidence for athletic performance is rated possibly ineffective — don't expect it to boost strength or endurance.

For benign prostatic hyperplasia (enlarged prostate), there isn't enough reliable evidence to rate it either way.

The evidence, ingredient by ingredient Tribulus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tribulus is generally well tolerated in the short term for healthy adults, though long-term safety data are limited. Gastrointestinal side effects like stomach pain, nausea, and diarrhea can occur, though in one study they happened at similar rates in people taking tribulus and those on placebo.

Rare serious effects reported include liver and kidney injury and seizures; one case involved very high intake over just two days. Avoid this product during pregnancy because it may affect hormones and safety isn't established.

Also avoid it while breastfeeding — there isn't enough reliable safety data.

Side effects, ingredient by ingredient Tribulus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tribulus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take blood pressure pills (antihypertensives), diabetes drugs, or lithium — all carry Moderate interaction risk with tribulus. Use the checker below to search your exact medications before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Tribulus may help with sexual function, though the evidence is modest. If you take blood pressure pills, diabetes medications, or lithium, talk to your pharmacist before adding this — the interactions can be serious.

For most other people, it's generally well tolerated short-term, but long-term safety is still unclear.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tribulus 2400, straight from the product label.

Brand iForce Nutrition
Barcode (UPC) 854503001398
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2017
DSLD ID 74686
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tribulus 2400 by iForce Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
854503001398
IngredientAmount% DV
Proprietary Tribulus 2400 Blend800 mg--
Bulgarian Tribulus terrestris extract0 NP--

Other ingredients: Rice Flour, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Ultra high potency Bulgarian Tribulus extract

Tribulus 2400 features a specific form of Bulgarian Tribulus Terrestris that is know for superior amounts of active saponins and protodioscin.

General Statements

Xtreme series

We live it, we breath it! Join the movement at www.iforcenation.com

These actives are the driving force behind Tribulus 2400's ability to promote rapid testosterone production and muscle gains!

Tribulus is scientifically proven to increase the production of leutinizing hormone, or LH.

By boosting the output of LH, your body will also increase its output of testosterone, which may support increased muscle mass and strength, and improved muscle recovery and endurance!

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule upon waking, 1 capsule mid-day, and 1 capsule prior to sleep. Continue use for 8-12 weeks.

FDA Disclaimer Statement

These statements have not been regulated by the Food and Drug Administration. This product is not intended to diagnose, treat, or cure any disease.

Brand IP Statement(s)

Supplementing Your Diet With iForce Nutrition's Ultra High Potency Tribulus 2400 May Promote: Increased testosterone & leutinizing hormone production Increased sex drive Increased muscle strength and power

This makes Tribulus 2400 more potent and more effective than lesser quality extracts on the market that will not deliver gains.

Precautions

Important Exceeding the recommended servings, not following the directions, or not following the warnings may lead to unwanted effects.

Warnings this product is only intended to be consumed by healthy individuals 18 years of age or older.

Pregnant or nursing women should not use this product. Consult with your health care provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product or if you have any pre-existing medical condition including but not limited to: High or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking MAO-B inhibitors or any other medication, including but not limited to MAOI's, SSRI's or any other compounds with serotonergic activity.

Do not combine with alcohol. Discontinue use and immediately consult your health care professional of you experience any adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing. User assumes all risks, liabilities or consequences respecting testing.

Keep out of reach of children.

Storage

Please store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tribulus 2400 by iForce Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tribulus 2400 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tribulus 2400 by iForce Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Proprietary Tribulus 2400 Blend

Interacts with
259 drugs
800 mg per serving

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims...

Proprietary Tribulus 2400 Blend monograph & interactions

Other (inactive) ingredients: Rice Flour, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tribulus 2400 by iForce Nutrition Drug Interactions

Want to check YOUR meds against Tribulus 2400?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
259 Moderate

Ingredients driving the most interactions

Proprietary Tribulus 2400 Blend 259

Individual Drug Interactions

The ingredients in Tribulus 2400 interact with 259 drugs. Click any drug to see the details.

1 of the 1 ingredient in Tribulus 2400 interact with drugs. Each result below shows which ingredient is responsible. Proprietary Tribulus 2400 Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Tribulus 2400 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Proprietary Tribulus 2400 Blend3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Proprietary Tribulus 2400 Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tribulus 2400, from the product label.

iForce Nutrition

See all iForce Nutrition products
Name
Tribravus Enterprises, LLC
City
Vista
State
CA
ZipCode
92081
Phone Number
1-877-743-6460
Web Address
www.iforcenutrition.com
Pharmacist Counseling Corner

Tribulus 2400 by iForce Nutrition: Common Questions

Does Tribulus 2400 by iForce Nutrition interact with any medications?
Yes. Based on its ingredients, Tribulus 2400 has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tribulus 2400 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does tribulus really help with sexual function?
Tribulus terrestris is rated possibly effective for sexual dysfunction, which means some clinical evidence supports it, but the data aren't rock-solid. It's worth a try if you're interested, but manage your expectations.
Can I take this if I'm trying to build muscle or improve athletic performance?
For athletic performance, tribulus is rated possibly ineffective — the evidence doesn't support using it for strength or endurance gains. It's not the supplement for that goal.
What side effects should I watch for?
Most people tolerate it well. You might notice stomach upset — pain, cramping, nausea, diarrhea, or constipation — though studies show these happen about as often with placebo. Serious effects like liver or kidney injury are rare but have been reported.
Is it safe to take tribulus long-term?
Short-term use in healthy adults is generally well tolerated, but reliable long-term safety data are limited. If you're thinking of taking it for months or years, check with your pharmacist first.
Can I use this if I'm pregnant or breastfeeding?
No — avoid it during pregnancy because it may affect hormones and safety isn't established. Also avoid it while breastfeeding because there isn't enough safety data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tribulus 2400 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tribulus 2400 label
Go deeper

The Full Monographs Behind Tribulus 2400’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph →
Sources

Sources & How We Checked

Tribulus 2400's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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